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An add-on training program involving breathing exercises, cold exposure, and meditation attenuates inflammation and disease activity in axial spondyloarthritis – A proof of concept trial

English version

Autoři: G. A. Buijze ^aff001; H. M. Y. De Jong ^aff002; M. Kox ^aff003; M. G. van de Sande ^aff002; D. Van Schaardenburg ^aff002; R. M. Van Vugt ^aff005; C. D. Popa ^aff006; P. Pickkers ^aff003; D. L. P. Baeten ^aff002
Působiště autorů: Department of Orthopaedic Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands ^aff001; Department of Rheumatology and Clinical Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam Rheumatology and Immunology Center, Amsterdam, The Netherlands ^aff002; Department of Intensive Care Medicine, Nijmegen Institute for Infection, Inflammation and Immunity, RadboudUMC Nijmegen, Nijmegen, The Netherlands ^aff003; Reade, Amsterdam Rheumatology and Immunology Center, Amsterdam, The Netherlands ^aff004; Department of Rheumatology and Clinical Immunology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands ^aff005; Department of Rheumatology, Sint Maartenskliniek, Nijmegen, The Netherlands ^aff006; Department of Rheumatology, RadboudUMC Nijmegen, Nijmegen, The Netherlands ^aff007
Vyšlo v časopise: PLoS ONE 14(12)
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pone.0225749

Souhrn

Objectives

The primary objective of this trial was to assess safety and anti-inflammatory effects of an add-on training program involving breathing exercises, cold exposure, and meditation in patients with axial spondyloarthritis

Methods

This study was an open-label, randomised, one-way crossover clinical proof-of-concept trial. Twenty-four patients with moderately active axial spondyloarthritis(ASDAS >2.1) and hs-CRP ≥5mg/L were included and randomised to an intervention (n = 13) and control group (n = 11) group that additionally received the intervention after the control period. The intervention period lasted for 8 weeks. The primary endpoint was safety, secondary endpoints were change in hs-CRP, serum calprotectin levels and ESR over the 8-week period. Exploratory endpoints included disease activity measured by ASDAS-CRP and BASDAI, quality of life (SF-36, EQ-5D, EQ-5D VAS), and hospital anxiety and depression (HADS).

Results

We found no significant differences in adverse events between groups, with one serious adverse event occurring 8 weeks after end of the intervention and judged ‘unrelated’. During the 8-week intervention period, there was a significant decline of ESR from (median [interquartile range] to 16 [9–26.5] to 9 [5–23] mm/hr, p = 0.040, whereas no effect was found in the control group (from 14 [8.3–27.3] to 16 [5–37] m/hr, p = 0.406). ASDAS-CRP declined from 3.1 [2.5–3.6] to 2.3 [1.9–3.2] in the intervention group (p = 0.044). A similar trend was observed for serum calprotectin (p = 0.064 in the intervention group versus p = 0.182 in the control group), but not for hs-CRP.

Conclusions

This proof-of-concept study in axial spondyloarthritis met its primary endpoint with no safety signals during the intervention. There was a significant decrease in ESR levels and ASDAS-CRP upon the add-on training program in the intervention group. These findings warrant full-scale randomised controlled trials of this novel therapeutic approach in patients with inflammatory conditions.

Trial registration

ClinicalTrials.gov; NCT02744014

Klíčová slova:

Immune response – Quality of life – Adverse events – Exercise – Inflammatory bowel disease – Inflammatory diseases – NSAIDs – Breathing

Zdroje

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2. Kox M, van Eijk LT, Zwaag J, van den Wildenberg J, Sweep FCGJ, van der Hoeven JG, et al. Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans. Proc Natl Acad Sci U S A. 2014;111(20):7379–84. doi: 10.1073/pnas.1322174111 24799686

3. Dougados M, Baeten D. Spondyloarthritis. Lancet. 2011;377(9783):2127–37. doi: 10.1016/S0140-6736(11)60071-8 21684383

4. Ambarus C, Yeremenko N, Tak PP, Baeten D. Pathogenesis of spondyloarthritis. Curr Opin Rheumatol. 2012;24(4):351–8. doi: 10.1097/BOR.0b013e3283534df4 22488076

5. van Tok MN, Satumtira N, Dorris M, Pots D, Slobodin G, van de Sande MG, et al. Innate immune activation can trigger experimental spondyloarthritis in HLA-B27/Huβ2m Transgenic Rats. Front Immunol. 2017;8(AUG):1–12.

6. Rudwaleit M, van der Heijde D, Landewé R, Listing J, Akkoc N, Brandt J, et al. The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis. 2009;68(6):777–83. doi: 10.1136/ard.2009.108233 19297344

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Článek Late Glacial rapid climate change and human response in the Westernmost Mediterranean (Iberia and Morocco)

Článek The role of endothelial MERTK during the inflammatory response in lungs

Článek Significant hearing loss in Fabry disease: Study of the Danish nationwide cohort prior to treatment

Článek Establishment of chemosensitivity tests in triple-negative and BRCA-mutated breast cancer patient-derived xenograft models

Článek An epidemiological study of visceral leishmaniasis in North East Ethiopia using serological and leishmanin skin tests

Článek Dissociations of oral foci of infections with infectious complications and survival after haematopoietic stem cell transplantation

Článek Latin American consumption of major food groups: Results from the ELANS study

Článek The seroconversion rate of QuantiFERON-TB Gold In-Tube test in psoriatic patients receiving secukinumab and ixekizumab, the anti-interleukin-17A monoclonal antibodies

Článek Does prior knowledge of food fraud affect consumer behavior? Evidence from an incentivized economic experiment

Článek Isolation and characterization of the EgWRI1 promoter from oil palm (Elaeis guineensis Jacq.) and its response to environmental stress and ethylene

Článek Bridge to neuroscience workshop: An effective educational tool to introduce principles of neuroscience to Hispanics students

Článek Plasma metabolites as possible biomarkers for diagnosis of breast cancer

Článek Investigating gene expression profiles of whole blood and peripheral blood mononuclear cells using multiple collection and processing methods

Článek Altitude and human disturbance are associated with helminth diversity in an endangered primate, Procolobus gordonorum

Článek “My mother in-law forced my husband to divorce me”: Experiences of women with infertility in Zamfara State of Nigeria

Článek The technological, organizational and environmental determinants of adoption of mobile health applications (m-health) by hospitals in Kenya

Článek Reaction-diffusion memory unit: Modeling of sensitization, habituation and dishabituation in the brain

Článek Early rise in central venous pressure during a spontaneous breathing trial: A promising test to identify patients at high risk of weaning failure?

Článek The computational analyses of handwriting in individuals with psychopathic personality disorder

Článek Consumption of psychoactive substances in prison: Between initiation and improvement, what trajectories occur after incarceration? COSMOS study data

Článek Prevalence of damaged and missing teeth among women in the southern plains of Nepal: Findings of a simplified assessment tool

Článek A global model for predicting the arrival of imported dengue infections

Článek Anxiety reduction through art therapy in women. Exploring stress regulation and executive functioning as underlying neurocognitive mechanisms

Článek The properties and formation mechanism of oat β-glucan mixed gels with different molecular weight composition induced by high-pressure processing

Článek Acceptability of early childhood obesity prediction models to New Zealand families

Článek Abundance of ethnically biased microsatellites in human gene regions

Článek Analysing trajectories of a longitudinal exposure: A causal perspective on common methods in lifecourse research

Článek Malaria screening at the workplace in Cameroon

Článek Genetic and morphological divergence in the warm-water planktonic foraminifera genus Globigerinoides

Článek The association between chronic periodontitis and oral Helicobacter pylori: A meta-analysis

Článek Using species distribution models to predict potential hot-spots for Rift Valley Fever establishment in the United Kingdom

Článek Disturbance study of seismic vibrator reaction mass and piston

Článek Gene expression is associated with virulence in murine macrophages infected with Leptospira spp

Článek Polysubstance use patterns and novel synthetics: A cluster analysis from three U.S. cities

Článek Vernonia polysphaera Baker: Anti-inflammatory activity in vivo and inhibitory effect in LPS-stimulated RAW 264.7 cells

Článek Cost-effectiveness of prenatal screening and diagnostic strategies for Down syndrome: A microsimulation modeling analysis

Článek Prevalence of drug–drug interaction in atrial fibrillation patients based on a large claims data

Článek The logic of basic education provision and public goods preferences in Chinese fiscal federalism

Článek The Black identity, hair product use, and breast cancer scale

Článek Diversity and distribution of microbial communities in floral nectar of two night-blooming plants of the Sonoran Desert

Článek Examining differences in cigarette smoking prevalence among young adults across national surveillance surveys

Článek Reversed metabolic reprogramming as a measure of cancer treatment efficacy in rat C6 glioma model

Článek Impact of perceived distances on international tourism

Článek Effect of diabetes on incidence of peritoneal dialysis-associated peritonitis

Článek The prognostic value of myeloid derived suppressor cell level in hepatocellular carcinoma: A systematic review and meta-analysis

Článek Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis

Článek Alligators in the abyss: The first experimental reptilian food fall in the deep ocean

Článek A novel power-driven fractional accumulated grey model and its application in forecasting wind energy consumption of China

Článek Long-term ambient hydrocarbons exposure and incidence of ischemic stroke

Článek Chronic unexplained nausea in adults: Prevalence, impact on quality of life, and underlying organic diseases in a cohort of 5096 subjects comprehensively investigated

Článek Evaluation of a nanophosphor lateral-flow assay for self-testing for herpes simplex virus type 2 seropositivity

Článek Normal and altered masticatory load impact on the range of craniofacial shape variation: An analysis of pre-Hispanic and modern populations of the American Southern Cone

Článek Assessing recall of personal sun exposure by integrating UV dosimeter and self-reported data with a network flow framework

Článek Quantification of speech and synchrony in the conversation of adults with autism spectrum disorder

Článek Genome-wide association study of drought tolerance and biomass allocation in wheat

Článek An examination of the association between early initiation of substance use and interrelated multilevel risk and protective factors among adolescents

Článek Pelagic tunicates at shallow hydrothermal vents of Kueishantao

Článek Aegicetus gehennae, a new late Eocene protocetid (Cetacea, Archaeoceti) from Wadi Al Hitan, Egypt, and the transition to tail-powered swimming in whales

Článek Changing landscape configuration demands ecological planning: Retrospect and prospect for megaherbivores of North Bengal

Článek Analyzing linguistic variation and change using gamification web apps: The case of German-speaking Europe

Článek Factors associated with condom use among HIV-positive women living in Atlanta, Georgia

Článek Watered-down biodiversity? A comparison of metabarcoding results from DNA extracted from matched water and bulk tissue biomonitoring samples

Článek Identification and impact of stable prognostic biochemical markers for cold-induced sweetening resistance on selection efficiency in potato (Solanum tuberosum L.) breeding programs

Článek What do we really know about the appropriateness of radiation emitting imaging for low back pain in primary and emergency care? A systematic review and meta-analysis of medical record reviews

Článek Naïve/Effector CD4 T cell ratio as a useful predictive marker of immune reconstitution in late presenter HIV patients: A multicenter study

Článek C5aR agonist enhances phagocytosis of fibrillar and non-fibrillar Aβ amyloid and preserves memory in a mouse model of familial Alzheimer’s disease

Článek Channel-spatial attention network for fewshot classification

Článek The evolution and genetic diversity of avian influenza A(H9N2) viruses in Cambodia, 2015 – 2016

Článek Withdrawn medicines included in the essential medicines lists of 136 countries

Článek The optimal delivery time and order quantity in an oligopoly market with time-sensitive customers

Článek Feature identification in time-indexed model output

Článek Influence of microwave-assisted dehydration on morphological integrity and viability of cat ovarian tissues: First steps toward long-term preservation of complex biomaterials at supra-zero temperatures

Článek Healing The Past By Nurturing The Future: A qualitative systematic review and meta-synthesis of pregnancy, birth and early postpartum experiences and views of parents with a history of childhood maltreatment

Článek Relationship between land surface temperature and fraction of anthropized area in the Atlantic forest region, Brazil

Článek The coevolution of contagion and behavior with increasing and decreasing awareness

Článek Seeking snow and breathing hard – Behavioral tactics in high elevation mammals to combat warming temperatures

Článek A simplistic approach of algal biofuels production from wastewater using a Hybrid Anaerobic Baffled Reactor and Photobioreactor (HABR-PBR) System

Článek Viral load testing among women on ‘option B+’ in Mazowe, Zimbabwe: How well are we doing?

Článek Application of enhanced assimilable organic carbon method across operational drinking water systems

Článek Interactions of pharmaceutical companies with world countries, cancers and rare diseases from Wikipedia network analysis

Článek New fossils of Elateridae (Insecta, Coleoptera) from Early Cretaceous Jinju Formation (South Korea) with their implications to evolutionary diversity of extinct Protagrypninae

Článek Establishment of normative ranges of the healthy human immune system with comprehensive polychromatic flow cytometry profiling

Článek Variations of training load, monotony, and strain and dose-response relationships with maximal aerobic speed, maximal oxygen uptake, and isokinetic strength in professional soccer players

Článek NF-κB-mediated regulation of rat CYP2E1 by two independent signaling pathways

Článek Transcranial magnetic stimulation induced early silent period and rebound activity re-examined

Článek Heterogenous wealth effects of minimum unit price on purchase of alcohol: Evidence using scanner data

Článek Effectiveness of integrative medicine group visits in chronic pain and depressive symptoms: A randomized controlled trial

Článek Associations between adverse childhood family environments and blood pressure differ between men and women

Článek Comparative analysis of the vaginal microbiome of pregnant women with either Trichomonas vaginalis or Chlamydia trachomatis

Článek Colorectal cancer incidence among young adults in England: Trends by anatomical sub-site and deprivation

Článek Assessing service and treatment needs and barriers of youth who use illicit and non-medical prescription drugs in Northern Ontario, Canada

Článek Diet and feeding strategy of Northeast Atlantic mackerel (Scombrus scomber) in Icelandic waters

Článek Agricultural intensification was associated with crop diversification in India (1947-2014)

Článek IL-18/IL-37/IP-10 signalling complex as a potential biomarker for discriminating active and latent TB

Článek Lie prevalence, lie characteristics and strategies of self-reported good liars

Článek Prevalent, persistent anal HPV infection and squamous intraepithelial lesions: Findings from a cohort of men living with HIV in South Africa

Článek Assessment of the real-world safety profile of vedolizumab using the United States Food and Drug Administration adverse event reporting system

Článek Machine learning approach to single nucleotide polymorphism-based asthma prediction

Článek Local risk perception enhances epidemic control

Článek Immuno-metabolic profile of human macrophages after Leishmania and Trypanosoma cruzi infection

Článek Phylogenetic position of the ‘extinct’ Fijian coconut moth, Levuana iridescens (Lepidoptera: Zygaenidae)

Článek Association between cardiovascular diseases and pregnancy-induced hypertensive disorders in a population of Cameroonian women at Yaoundé: A case-control study

Článek Location of sources in reaction-diffusion equations using support vector machines

Článek Methylsulfonylmethane increases osteogenesis and regulates the mineralization of the matrix by transglutaminase 2 in SHED cells

Článek Four months vitamin D supplementation to vitamin D insufficient individuals does not improve muscular strength: A randomized controlled trial

Článek Hyperglycemia induces key genetic and phenotypic changes in human liver epithelial HepG2 cells which parallel the Leprdb/J mouse model of non-alcoholic fatty liver disease (NAFLD)

Článek Preoperative and operation-related risk factors for postoperative nosocomial infections in pediatric patients: A retrospective cohort study

Článek Differences between individuals with schizophrenia or obsessive-compulsive disorder and healthy controls in social cognition and mindfulness skills: A controlled study

Článek Variations by sex and age in the association between alcohol use and depressed mood among Thai adolescents

Článek Undernutrition is associated with perturbations in T cell-, B cell-, monocyte- and dendritic cell- subsets in latent Mycobacterium tuberculosis infection

Článek RNA-sequencing reveals that STRN, ZNF484 and WNK1 add to the value of mitochondrial MT-COI and COX10 as markers of unstable coronary artery disease

Článek Human gut microbiota is associated with HIV-reactive immunoglobulin at baseline and following HIV vaccination

Článek Is un stylo sharper than une épée? Investigating the interaction of sound symbolism and grammatical gender in English and French speakers

Článek Shifting perceptions of female genital cutting in a Swedish migration context

Článek Nucleotide composition affects codon usage toward the 3'-end

Článek Effects of continuity of care on the postradiotherapy survival of working-age patients with oral cavity cancer: A nationwide population-based cohort study in Taiwan

Článek Self-reported attitudes, knowledge and skills of using evidence-based medicine in daily health care practice: A national survey among students of medicine and health sciences in Hungary

Článek Development of refractive error in children treated for retinopathy of prematurity with anti-vascular endothelial growth factor (anti-VEGF) agents: A meta-analysis and systematic review

Článek High diversity of coralline algae in New Zealand revealed: Knowledge gaps and implications for future research

Článek Electromyographic characteristics of pelvic floor muscles in women with stress urinary incontinence following sEMG-assisted biofeedback training and Pilates exercises

Článek Up on the roof and down in the dirt: Differences in substrate properties (SOM, potassium, phosphorus and pH) and their relationships to each other between sedum and wildflower green roofs

Článek Sap flow of Salix psammophila and its principal influencing factors at different slope positions in the Mu Us desert

Článek Does in vitro selection of biocontrol agents guarantee success in planta? A study case of wheat protection against Fusarium seedling blight by soil bacteria

Článek Highly multiplexed quantitative PCR-based platform for evaluation of chicken immune responses

Článek Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments

Článek Research trends in farmers’ mental health: A scoping review of mental health outcomes and interventions among farming populations worldwide

Článek HR-pQCT imaging in children, adolescents and young adults: Systematic review and subgroup meta-analysis of normative data

Článek Limits in reliability of leg-spring and joint stiffness measures during single-leg hopping within a sled-based system

Článek Genomic and phylogenetic analysis of choriolysins, and biological activity of hatching liquid in the flatfish Senegalese sole

Článek Physical activity levels in adults and elderly from triaxial and uniaxial accelerometry. The Tromsø Study

Článek Pathologic changes and immune responses against Coxiella burnetii in mice following infection via non-invasive intratracheal inoculation

Článek 4D perfusion CT of prostate cancer for image-guided radiotherapy planning: A proof of concept study

Článek Rapid wound healing in a reef manta ray masks the extent of vessel strike

Článek Motor vehicle crash reconstruction: Does it relate to the heterogeneity of whiplash recovery?

Článek Frequency and determinants of health care utilization for symptomatic reproductive tract infections in rural Indian women: A cross-sectional study

Článek BPRF: Blockchain-based privacy-preserving reputation framework for participatory sensing systems

Článek Gang confrontation: The case of Medellin (Colombia)

Článek Adaptive smartphone-based sensor fusion for estimating competitive rowing kinematic metrics

Článek Prevalence of Cryptococcal Antigenemia and associated factors among HIV/AIDS patients on second-line antiretroviral therapy at two hospitals in Western Oromia, Ethiopia

Článek Characterization of the cecal microbiome composition of Wenchang chickens before and after fattening

Článek A leader-follower model for discrete competitive facility location problem under the partially proportional rule with a threshold

Článek Process elements contributing to community mobilization for HIV risk reduction and gender equality in rural South Africa

Článek Hidden dynamics of soccer leagues: The predictive ‘power’ of partial standings

Článek Quantitative dynamics of Salmonella and E. coli in feces of feedlot cattle treated with ceftiofur and chlortetracycline

Článek Diet of the brown bear in Himalaya: Combining classical and molecular genetic techniques

Článek Multiscale analysis for patterns of Zika virus genotype emergence, spread, and consequence

Článek Incidences of community onset severe sepsis, Sepsis-3 sepsis, and bacteremia in Sweden – A prospective population-based study

Článek Antiphagocytic protein 1 increases the susceptibility of Cryptococcus neoformans to amphotericin B and fluconazole

Článek Towards text mining therapeutic change: A systematic review of text-based methods for Therapeutic Change Process Research

Článek Intrinsic group behaviour II: On the dependence of triad spatial dynamics on social and personal features; and on the effect of social interaction on small group dynamics

Článek Association between circulating neuregulin4 levels and diabetes mellitus: A meta-analysis of observational studies

Článek Impact of relational leadership on employees’ unethical pro-organizational behavior: A survey based on tourism companies in four countries

Článek Using morphological attributes for the fast assessment of nutritional responses of Buddhist pine (Podocarpus macrophyllus [Thunb.] D. Don) seedlings to exponential fertilization

Článek Student engagement, assessed using heart rate, shows no reset following active learning sessions in lectures

Článek Direct costs of illness of patients with chronic cough in rural Malawi—Experiences from Dowa and Ntchisi districts

Článek Bone spoons for prehistoric babies: Detection of human teeth marks on the Neolithic artefacts from the site Grad-Starčevo (Serbia)

Článek Identifying and characterizing extrapolation in multivariate response data

Článek Clinically-defined preoperative serum phosphorus abnormalities and outcomes of coronary artery bypass grafting: Retrospective analysis using inverse probability weighting adjustment

Článek My experiences with kidney care: A qualitative study of adults in the Northern Territory of Australia living with chronic kidney disease, dialysis and transplantation

Článek Anemia and associated factors among type-2 diabetes mellitus patients attending public hospitals in Harari Region, Eastern Ethiopia

Článek The KLDpT activation loop motif is critical for MARK kinase activity

Článek Pro-renin receptor suppresses mitochondrial biogenesis and function via AMPK/SIRT-1/ PGC-1α pathway in diabetic kidney

Článek Evaluation of upconverting nanoparticles towards heart theranostics

Článek Severe childhood anemia and emergency blood transfusion in Gadarif Hospital, eastern Sudan

Článek Gender differences in the effect of self-rated health (SRH) on all-cause mortality and specific causes of mortality among individuals aged 50 years and older

Článek PyLandStats: An open-source Pythonic library to compute landscape metrics

Článek Snow avalanche deaths in Switzerland from 1995 to 2014—Results of a nation-wide linkage study

Článek Cashew nuts (Anacardium occidentale L.) decrease visceral fat, yet augment glucose in dyslipidemic rats

Článek Generation of targeted homozygosity in the genome of human induced pluripotent stem cells

Článek Pathways to care and outcomes among hospitalised HIV-seropositive persons with cryptococcal meningitis in South Africa

Článek Fungicides, herbicides and bees: A systematic review of existing research and methods

Článek The risk of active tuberculosis among individuals living in tuberculosis-affected households in the Republic of Korea, 2015

Článek Intraoperative ketorolac in high-risk breast cancer patients. A prospective, randomized, placebo-controlled clinical trial

Článek Comparative study of the composition of cultivated, naturally grown Cordyceps sinensis, and stiff worms across different sampling years

Článek Factors affecting the spread of multiple information in social networks

Článek Non-structural carbohydrates in maize with different nitrogen tolerance are affected by nitrogen addition

Článek Network dynamics of Broca’s area during word selection

Článek Is less readable liked better? The case of font readability in poetry appreciation

Článek An expanded rating curve model to estimate river discharge during tidal influences across the progressive-mixed-standing wave systems

Článek Neuroimaging modality fusion in Alzheimer’s classification using convolutional neural networks

Článek Ginkgo biloba extract increases neurite outgrowth and activates the Akt/mTOR pathway

Článek Systematic review and meta-analysis comparing Adjustable Transobturator Male System (ATOMS) and Adjustable Continence Therapy (ProACT) for male stress incontinence

Článek Men and women differ in their perception of gender bias in research institutions

Článek Visual inspection of vaccine storage conditions in general practices: A study of 75 vaccine refrigerators

Článek Serum procalcitonin as an independent diagnostic markers of bacteremia in febrile patients with hematologic malignancies

Článek New physiological bench test reproducing nocturnal breathing pattern of patients with sleep disordered breathing

Článek Respiratory syncytial virus exhibits differential tropism for distinct human placental cell types with Hofbauer cells acting as a permissive reservoir for infection

Článek Correlation analysis of physical fitness and retinal microvasculature by OCT angiography in healthy adults

Článek Non-spherical particles in optical tweezers: A numerical solution

Článek Polyvinylalcohol-carbazate (PVAC) reduces red blood cell hemolysis

Článek Single nucleotide polymorphisms associated with susceptibility for development of colorectal cancer: Case-control study in a Basque population

Článek Fragment-based design of small molecule PCSK9 inhibitors using simulated annealing of chemical potential simulations

Článek Development and validation of the Scale of Motives for Using Social Networking Sites (SMU-SNS) for adolescents and youths

Článek Formation of a structurally-stable conformation by the intrinsically disordered MYC:TRRAP complex

Článek Generation of swine movement network and analysis of efficient mitigation strategies for African swine fever virus

Článek Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats

Článek The Determinants of Household Food Waste Generation and its Associated Caloric and Nutrient Losses: The Case of Lebanon

Článek Housekeeping gene validation for RT-qPCR studies on synovial fibroblasts derived from healthy and osteoarthritic patients with focus on mechanical loading

Článek Does historical land use affect the regional distribution of fleshy-fruited woody plants?

Článek ABO blood group and risk of newly diagnosed nonalcoholic fatty liver disease: A case-control study in Han Chinese population

Článek Circulation of influenza virus from 2009 to 2018 in Cameroon: 10 years of surveillance data

Článek Parametric CAD modeling for open source scientific hardware: Comparing OpenSCAD and FreeCAD Python scripts

Článek The diversity and abundance of fungi and bacteria on the healthy and dandruff affected human scalp

Článek Interferometric fluorescence cross correlation spectroscopy

Článek Fatty acid profiling of 75 Indian snack samples highlights overall low trans fatty acid content with high polyunsaturated fatty acid content in some samples

Článek Evaluating the impact of setting delineators in tunnels based on drivers’ visual characteristics

Článek Quinolone nonsusceptibility among enteric pathogens isolated from international travelers – Foodborne Diseases Active Surveillance Network (FoodNet) and National Antimicrobial Monitoring System (NARMS), 10 United States sites, 2004 – 2014

Článek Influence of Debaryomyces hansenii on bacterial lactase gene diversity in intestinal mucosa of mice with antibiotic-associated diarrhea

Článek Food from faeces: Evaluating the efficacy of scat DNA metabarcoding in dietary analyses

Článek Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells

Článek Prediction model for dengue fever based on interactive effects between multiple meteorological factors in Guangdong, China (2008–2016)

Článek Antihypertensive treatment and risk of cardiovascular mortality in patients with chronic kidney disease diagnosed based on the presence of proteinuria and renal function: A large longitudinal study in Japan

Článek Circadian misalignment alters insulin sensitivity during the light phase and shifts glucose tolerance rhythms in female mice

Článek Commonly missed nursing cares in the obstetrics and gynecologic wards of Tigray general hospitals; Northern Ethiopia

Článek Preparedness for colorectal cancer surgery and recovery through a person-centred information and communication intervention – A quasi-experimental longitudinal design

Článek Detrended Fluctuation Analysis in the prediction of type 2 diabetes mellitus in patients at risk: Model optimization and comparison with other metrics

Článek A co-registration investigation of inter-word spacing and parafoveal preview: Eye movements and fixation-related potentials

Článek Wireless intravesical device for real-time bladder pressure measurement: Study of consecutive voiding in awake minipigs

Článek Sequence analyses at mitochondrial and nuclear loci reveal a novel Theileria sp. and aid in the phylogenetic resolution of piroplasms from Australian marsupials and ticks

Článek Use of three points to determine the accuracy of guided implantation

Článek Citric-acid dialysate improves the calcification propensity of hemodialysis patients: A multicenter prospective randomized cross-over trial

Článek Plasmacytoid dendritic cell and myeloid dendritic cell function in ageing: A comparison between elderly and young adult women

Článek Predicting the replicability of social science lab experiments

Článek Lomax exponential distribution with an application to real-life data

Článek Territoriality and the organization of technology during the Last Glacial Maximum in southwestern Europe

Článek Global longitudinal strain can predict heart failure exacerbation in stable outpatients with ischemic left ventricular systolic dysfunction

Článek Barriers to chronic Hepatitis B treatment and care in Ghana: A qualitative study with people with Hepatitis B and healthcare providers

Článek The evaluation of the Woman’s Condom marketing approach: What value did peer-led interpersonal communication add to the promotion of a new female condom in urban Lusaka?

Článek Discovery of genomic variations by whole-genome resequencing of the North American Araucana chicken

Článek A siRNA mediated hepatic dpp4 knockdown affects lipid, but not glucose metabolism in diabetic mice

Článek Central sensitization in knee osteoarthritis and fibromyalgia: Beyond depression and anxiety

Článek A Bayesian Monte Carlo approach for predicting the spread of infectious diseases

Článek Clinical and epidemiological characteristics of imported dengue fever among inbound passengers: Infrared thermometer–based active surveillance at an international airport

Článek Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots

Článek Impact of oral probiotic Lactobacillus acidophilus vaccine strains on the immune response and gut microbiome of mice

Článek An investigation of the equine epidermal growth factor system during hyperinsulinemic laminitis

Článek Ranking hospitals when performance and risk factors are correlated: A simulation-based comparison of risk adjustment approaches for binary outcomes

Článek The effect of carbohydrate sources: Sucrose, invert sugar and components of mānuka honey, on core bacteria in the digestive tract of adult honey bees (Apis mellifera)

Článek Runs of Homozygosity and NetView analyses provide new insight into the genome-wide diversity and admixture of three German cattle breeds

Článek Backward compatibility of whole genome sequencing data with MLVA typing using a new MLVAtype shiny application for Vibrio cholerae

Článek Total sleep deprivation increases pain sensitivity, impairs conditioned pain modulation and facilitates temporal summation of pain in healthy participants

Článek Dynamics of essential interaction between firms on financial reports

Článek Drug overdose among women in intimate relationships: The role of partner violence, adversity and relationship dependencies

Článek California condor microbiomes: Bacterial variety and functional properties in captive-bred individuals

Článek Using baited remote underwater videos (BRUVs) to characterize chondrichthyan communities in a global biodiversity hotspot

Článek Evaluation of the potential of a new ribavirin analog impairing the dissemination of ovarian cancer cells

Článek Molecular characterization of fowl adenovirus isolate of Malaysia attenuated in chicken embryo liver cells and its pathogenicity and immunogenicity in chickens

Článek Prolonged fasting followed by refeeding modifies proteome profile and parvalbumin expression in the fast-twitch muscle of pacu (Piaractus mesopotamicus)

Článek Influence of a neck compression collar on cerebrovascular and autonomic function in men and women

Článek Visceral leishmaniasis in Northeast Brazil: What is the impact of HIV on this protozoan infection?

Článek βC1, pathogenicity determinant encoded by Cotton leaf curl Multan betasatellite, interacts with calmodulin-like protein 11 (Gh-CML11) in Gossypium hirsutum

Článek Expanded eligibility for HIV testing increases HIV diagnoses—A cross-sectional study in seven health facilities in western Kenya

Článek Clinically useful limited sampling strategy to estimate area under the concentration-time curve of once-daily tacrolimus in adult Japanese kidney transplant recipients

Článek Re-introduction of dengue virus serotype 2 in the state of Rio de Janeiro after almost a decade of epidemiological silence

Článek The salivary gland proteome of root-galling grape phylloxera (Daktulosphaira vitifoliae Fitch) feeding on Vitis spp.

Článek Efficacy of antimalarial drugs for treatment of uncomplicated falciparum malaria in Asian region: A network meta-analysis

Článek A study of the impact of data sharing on article citations using journal policies as a natural experiment

Článek The higher they go the harder they could fall: The impact of risk-glorifying commercials on risk behavior

Článek Optimization of TripleTOF spectral simulation and library searching for confident localization of phosphorylation sites

Článek Evidence for pre-climacteric activation of AOX transcription during cold-induced conditioning to ripen in European pear (Pyrus communis L.)

Článek Expression of myeloid Src-family kinases is associated with poor prognosis in AML and influences Flt3-ITD kinase inhibitor acquired resistance

Článek Modeling record scores in the snatch and its variations in the long-term training of young weightlifters

Článek Women with metabolic syndrome show similar health benefits from high-intensity interval training than men

Článek Long-term tracking demonstrates effectiveness of a partnership-led training program to advance the careers of biomedical researchers from underrepresented groups

Článek Serological evidence of arboviruses and coccidia infecting horses in the Amazonian region of Brazil

Článek Do cancer stem cells exist? A pilot study combining a systematic review with the hierarchy-of-hypotheses approach

Článek Diversity of a cytokinin dehydrogenase gene in wild and cultivated barley

Článek PyRates—A Python framework for rate-based neural simulations

Článek Interdependence of balance mechanisms during bipedal locomotion

Článek Ecological interdependencies and resource competition: The role of information and communication in promoting effective collaboration in complex management situations

Článek Quaking-induced conversion of prion protein on a thermal mixer accelerates detection in brains infected with transmissible spongiform encephalopathy agents

Článek A new finite element based parameter to predict bone fracture

Článek Clinical, imaging features and outcome in internal carotid artery versus middle cerebral artery disease

Článek The association of weight status and weight perception with number of confidants in adolescents

Článek Smoking trajectories and risk of stroke until age of 50 years – The Northern Finland Birth Cohort 1966

Článek Discoidin domain Receptor 2: A determinant of metabolic syndrome-associated arterial fibrosis in non-human primates

Článek L-lysine protects C2C12 myotubes and 3T3-L1 adipocytes against high glucose damages and stresses

Článek IGF-1-enhanced miR-513a-5p signaling desensitizes glioma cells to temozolomide by targeting the NEDD4L-inhibited Wnt/β-catenin pathway

Článek Performance, complexity and dynamics of force maintenance and modulation in young and older adults

Článek Selection of appropriate reference genes for quantitative real-time reverse transcription PCR in Betula platyphylla under salt and osmotic stress conditions

Článek A method for complete plant taxon and site inventories in large forest areas with the help of orienteering maps, as exemplified by target forests in Switzerland

Článek Bilateral Parkinson’s disease model rats exhibit hyperalgesia to subcutaneous formalin administration into the vibrissa pad

Článek Microbial diversity and mineral composition of weathered serpentine rock of the Khalilovsky massif

Článek Interaction strength in plant-pollinator networks: Are we using the right measure?

Článek Erastin, a ferroptosis-inducing agent, sensitized cancer cells to X-ray irradiation via glutathione starvation in vitro and in vivo

Článek Psychometric properties of the PERMA Profiler for measuring wellbeing in Australian adults

Článek Host-mediated microbiome engineering (HMME) of drought tolerance in the wheat rhizosphere

Článek Trust development as an expectancy-learning process: Testing contingency effects

Článek Mutation analysis of annual sediment discharge at Wu Long station in Wu Jiang River Basin from 1960 to 2016

Článek Improving distribution models of riparian vegetation with mobile laser scanning and hydraulic modelling

Článek Skeletal muscle alterations in tachycardia-induced heart failure are linked to deficient natriuretic peptide signalling and are attenuated by RAS-/NEP-inhibition

Článek Comprehensive value assessment of drugs using a multi-criteria decision analysis: An example of targeted therapies for metastatic colorectal cancer treatment

Článek Leisure-time physical activity and sports in the Brazilian population: A social disparity analysis

Článek Robot-assisted unicompartmental knee arthroplasty can reduce radiologic outliers compared to conventional techniques

Článek Causes of inferior relative survival after testicular germ cell tumor diagnosed 1953–2015: A population-based prospective cohort study

Článek Mystery or method? Evaluating claims of increased energy expenditure during a ketogenic diet

Článek Commentary on: Abundance and distribution of microplastics within surface sediments of a key shellfish growing region of Canada

Článek The genetic and environmental effects on school grades in late childhood and adolescence

Článek Metabolic power in hurling with respect to position and halves of match-play

Článek Local, nonlinear effects of cGMP and Ca2+ reduce single photon response variability in retinal rods

Článek Personality traits and risky behavior among motorcyclists: An exploratory study

Článek The long-term arterial assist intermittent pneumatic compression generating venous flow obstruction is responsible for improvement of arterial flow in ischemic legs

Článek Human-nature relationships in context. Experiential, psychological, and contextual dimensions that shape children’s desire to protect nature

Článek The spatio-temporal patterns of the topsoil organic carbon density and its influencing factors based on different estimation models in the grassland of Qinghai-Tibet Plateau

Článek INT reduction is a valid proxy for eukaryotic plankton respiration despite the inherent toxicity of INT and differences in cell wall structure

Článek Gestational diabetes mellitus diagnosed at 24 to 28 weeks of gestation in older and obese Women: Is it too late?

Článek Hermetia illucens in diets for zebrafish (Danio rerio): A study of bacterial diversity by using PCR-DGGE and metagenomic sequencing

Článek Thermotolerant Campylobacter spp. in chicken and bovine meat in Italy: Prevalence, level of contamination and molecular characterization of isolates

Článek Prognostic value of maximum standard uptake value, metabolic tumor volume, and total lesion glycolysis of positron emission tomography/computed tomography in patients with breast cancer: A systematic review and meta-analysis

Článek Understanding the variability of handheld spectral-domain optical coherence tomography measurements in supine infants

Článek Helicobacter pylori antibody and pepsinogen testing for predicting gastric microbiome abundance

Článek Outcome of bimodality definitive chemoradiation does not differ from that of trimodality upfront neck dissection followed by adjuvant treatment for >6 cm lymph node (N3) head and neck cancer

Článek Belief in conspiracy theories: The predictive role of schizotypy, Machiavellianism, and primary psychopathy

Článek Does seed size mediate sex-specific reproduction costs in the Callosobruchus maculatus bean beetle?

Článek Characters matter: How narratives shape affective responses to risk communication

Článek First-4-week erythrocyte sedimentation rate variability predicts erythrocyte sedimentation rate trajectories and clinical course among patients with pyogenic vertebral osteomyelitis

Článek Walking with head-mounted virtual and augmented reality devices: Effects on position control and gait biomechanics

Článek Cohort Profile: The Dutch Perined-Lifelines birth cohort

Článek Accelerated development of rice stripe virus-resistant, near-isogenic rice lines through marker-assisted backcrossing

Článek Physical determinants of vault performance and their age-related differences across male junior and elite top-level gymnasts

Článek The transcriptome analysis of the Arabidopsis thaliana in response to the Vibrio vulnificus by RNA-sequencing

Článek Stable depletion of RUNX1-ETO in Kasumi-1 cells induces expression and enhanced proteolytic activity of Cathepsin G and Neutrophil Elastase

Článek Overweight and obesity are associated with clustering of metabolic risk factors in early pregnancy and the risk of GDM

Článek Genome-wide association mapping of total antioxidant capacity, phenols, tannins, and flavonoids in a panel of Sorghum bicolor and S. bicolor × S. halepense populations using multi-locus models

Článek Choosing important health outcomes for comparative effectiveness research: 5th annual update to a systematic review of core outcome sets for research

Článek Balancing fire risk and human thermal comfort in fire-prone urban landscapes

Článek Low-rank graph optimization for multi-view dimensionality reduction

Článek Time optimal entrainment control for circadian rhythm

Článek Why do football clubs fail financially? A financial distress prediction model for European professional football industry

Článek Reconstruction error based deep neural networks for coronary heart disease risk prediction

Článek Exploring the geography of serious mental illness and type 2 diabetes comorbidity in Illawarra—Shoalhaven, Australia (2010 -2017)

Článek To be or not to be an inclusive teacher: Are empathy and social dominance relevant factors to positive attitudes towards inclusive education?

Článek Seasonality of deaths with respect to age and cause in Chitral District Pakistan

Článek Myalgic encephalomyelitis/chronic fatigue Syndrome (ME/CFS): Investigating care practices pointed out to disparities in diagnosis and treatment across European Union

Článek Poor nutrition for under-five children from poor households in Ethiopia: Evidence from 2016 Demographic and Health Survey

Článek The effect of a curriculum-based physical activity intervention on accelerometer-assessed physical activity in schoolchildren: A non-randomised mixed methods controlled before-and-after study

Článek Safety and immune cell kinetics after donor natural killer cell infusion following haploidentical stem cell transplantation in children with recurrent neuroblastoma

Článek On-site blood culture incubation shortens the time to knowledge of positivity and microbiological results in septic patients

Článek In vivo ultrasound thermal ablation control using echo decorrelation imaging in rabbit liver and VX2 tumor

Článek Genome wide identification and characterization of microsatellite markers in black pepper (Piper nigrum): A valuable resource for boosting genomics applications

Článek Child behaviour and subsequent changes in body weight, composition and shape

Článek RBM3 and CIRP expressions in targeted temperature management treated cardiac arrest patients—A prospective single center study

Článek Segmentation of distal airways using structural analysis

Článek A single intra-articular injection of 2.0% non-chemically modified sodium hyaluronate vs 0.8% hylan G-F 20 in the treatment of symptomatic knee osteoarthritis: A 6-month, multicenter, randomized, controlled non-inferiority trial

Článek What effort is required in retrieving self-defining memories? Specific autonomic responses for integrative and non-integrative memories

Článek Influence of pre-pregnancy body mass index (p-BMI) and gestational weight gain (GWG) on DNA methylation and protein expression of obesogenic genes in umbilical vein

Článek Early recovery after endoscopic totally extraperitoneal (TEP) hernia repair in athletes with inguinal disruption: A prospective cohort study

Článek Extending the information content of the MALDI analysis of biological fluids via multi-million shot analysis

Článek Effects of the performance parameters of a wheelchair on the changes in the position of the centre of gravity of the human body in dynamic condition

Článek An analysis of atmospheric water vapor variations over a complex agricultural region using airborne imaging spectrometry

Článek Factors influencing harmonized health data collection, sharing and linkage in Denmark and Switzerland: A systematic review

Článek Intracerebroventricular administration of the thyroid hormone analog TRIAC increases its brain content in the absence of MCT8

Článek Gaze direction reveals implicit item and source memory in older adults

Článek Social influences on smoking cessation in mid-life: Prospective cohort of UK women

Článek Cord compression defined by MRI is the driving factor behind the decision to operate in Degenerative Cervical Myelopathy despite poor correlation with disease severity

Článek Characterization of testis-specific serine/threonine kinase 1-like (TSSK1-like) gene and expression patterns in diploid and triploid Pacific abalone (Haliotis discus hannai; Gastropoda; Mollusca) males

Článek Eavesdropping on dolphins: Investigating the habits of bottlenose dolphins (Tursiops truncatus) through fixed acoustic stations

Článek Modeling narrative structure and dynamics with networks, sentiment analysis, and topic modeling

Článek Screening colonoscopy and flexible sigmoidoscopy for reduction of colorectal cancer incidence: A case-control study

Článek Focal inputs are a potential origin of local field potential (LFP) in the brain regions without laminar structure

Článek Emergency Department visits due to intoxications in a Dutch university hospital: Occurrence, characteristics and health care costs

Článek The effects of isobaric and hyperbaric bupivacaine on maternal hemodynamic changes post spinal anesthesia for elective cesarean delivery: A prospective cohort study

Článek Child protection, domestic violence, and ethnic minorities: Narrative results from a mixed methods study in Australia

Článek Long-term outcome in patients after treatment for Cushing’s disease in childhood

Článek The effects of diurnal intermittent fasting on proinflammatory cytokine levels while controlling for sleep/wake pattern, meal composition and energy expenditure

Článek Snord94 expression level alters methylation at C62 in snRNA U6

Článek Gender differences in the interaction effect of cumulative risk and problem-focused coping on depression among adult employees

Článek The relation between local and distal muscle fat infiltration in chronic whiplash using magnetic resonance imaging

Článek Prevalence of hypothermia on admission to recovery room remains high despite a large use of forced-air warming devices: Findings of a non-randomized observational multicenter and pragmatic study on perioperative hypothermia prevalence in France

Článek De novo transcriptome analysis and identification of genes associated with immunity, detoxification and energy metabolism from the fat body of the tephritid gall fly, Procecidochares utilis

Článek Linking surveillance and clinical data for evaluating trends in bloodstream infection rates in neonatal units in England

Článek Women’s decision-making power and undernutrition in their children under age five in the Democratic Republic of the Congo: A cross-sectional study

Článek Ocular surface and tear film changes in workers exposed to organic solvents used in the dry-cleaning industry

Článek The interferon-gamma pathway is selectively up-regulated in the liver of patients with secondary hemophagocytic lymphohistiocytosis

Článek Serotonin modulates behavior-related neural activity of RID interneuron in Caenorhabditis elegans

Článek Risk factors of post-discharge under-five mortality among Danish children 1997-2016: A register-based study

Článek Apologies as signals for change? Implicit theories of personality and reactions to apologies during the #MeToo movement

Článek Correction: Modeling the natural history of fatty liver using lifestyle–related risk factors: Effects of body mass index (BMI) on the life–course of fatty liver

Článek Knee joint biomechanics in transtibial amputees in gait, cycling, and elliptical training

Článek The polarity protein Dlg5 regulates collective cell migration during Drosophila oogenesis

Článek Resolving fluorescent species by their brightness and diffusion using correlated photon-counting histograms

Článek Rapid loss of flight in the Aldabra white-throated rail

Článek Effects of acupuncture at Pericardium-6 and Stomach-36 on nausea, sedation and gastrointestinal motility in healthy dogs administered intravenous lidocaine infusions

Článek Classification of flavors in cigarillos and little cigars and their variable cellular and acellular oxidative and cytotoxic responses

Článek Image denoising via a non-local patch graph total variation

Článek Chemogenomic profiling to understand the antifungal action of a bioactive aurone compound

Článek Short-term treatment with a peroxisome proliferator-activated receptor α agonist influences plasma one-carbon metabolites and B-vitamin status in rats

Článek Elevation, an emotion for prosocial contagion, is experienced more strongly by those with greater expectations of the cooperativeness of others

Článek Efficient delipidation of a recombinant lung surfactant lipopeptide analogue by liquid-gel chromatography

Článek Isobaric mass tagging and triple quadrupole mass spectrometry to determine lipid biomarker candidates for Alzheimer's disease

Článek Awareness of polycystic ovary syndrome among obstetrician-gynecologists and endocrinologists in Northern Europe

Článek Maternal death review and surveillance: The case of Central Hospital, Benin City, Nigeria

Článek Assessing insomnia management in community pharmacy setting in Jordan: A simulated patient approach

Článek Mapping the EORTC QLQ-C30 and QLQ-H&N35 to the EQ-5D for head and neck cancer: Can disease-specific utilities be obtained?

Článek Increasing sika deer population density may change resource use by larval dung beetles

Článek The fertile grounds of reproductive activism in The Gambia: A qualitative study of local key stakeholders’ understandings and heterogeneous actions related to infertility

Článek Subtle changes in striatal muscarinic M1 and M4 receptor expression in the DYT1 knock-in mouse model of dystonia

Článek Using evidence when planning for trial recruitment: An international perspective from time-poor trialists

Článek Molecular identification of Ehrlichia, Anaplasma, Babesia and Theileria in African elephants and their ticks

Článek Does educational level predict hearing aid self-efficacy in experienced older adult hearing aid users from Latin America? Validation process of the Spanish version of the MARS-HA questionnaire

Článek Psychometric properties of the Portuguese version of the National Eye Institute Visual Function Questionnaire-25

Článek Chlamydiaceae in wild, feral and domestic pigeons in Switzerland and insight into population dynamics by Chlamydia psittaci multilocus sequence typing

Článek Longitudinal Doppler references for monochorionic twins and comparison with singletons

Článek Survey on Chlamydiaceae in cloacal swabs from Swiss turkeys demonstrates absence of Chlamydia psittaci and low occurrence of Chlamydia gallinacean

Článek Computational singular perturbation analysis of brain lactate metabolism

Článek Reproductive life-history strategies in a species-rich assemblage of Amazonian electric fishes

Článek Analyzing and interpreting spatial and temporal variability of the United States county population distributions using Taylor's law

Článek Direct comparison of retinal structure and function in retinitis pigmentosa by co-registering microperimetry and optical coherence tomography

Článek Cattle intestinal microbiota shifts following Escherichia coli O157:H7 vaccination and colonizationtravel

Článek The genetic diversity and population structure of Sophora alopecuroides (Faboideae) as determined by microsatellite markers developed from transcriptome

Článek Significant reduction of vancomycin resistant E. faecium in the Norwegian broiler population coincided with measures taken by the broiler industry to reduce antimicrobial resistant bacteria

Článek Dual-hemispheric transcranial direct current stimulation (tDCS) over primary motor cortex does not affect movement selection

Článek Pharmacological or genetic targeting of Transient Receptor Potential (TRP) channels can disrupt the planarian escape response

Článek Establishment and characterization of transformed goat primary cells by expression of simian virus 40 large T antigen for orf virus propagations

Článek Flax rust infection transcriptomics reveals a transcriptional profile that may be indicative for rust Avr genes

Článek Optimizing sgRNA length to improve target specificity and efficiency for the GGTA1 gene using the CRISPR/Cas9 gene editing system

Článek Diversity of A(H5N1) clade 2.3.2.1c avian influenza viruses with evidence of reassortment in Cambodia, 2014-2016

Článek The effects of kinesiology taping on experimentally-induced thermal and mechanical pain in otherwise pain-free healthy humans: A randomised controlled repeated-measures laboratory study

Článek Tobacco and E-cigarette use among cancer survivors in the United States

Článek Sharing of gut microbial strains between selected individual sets of twins cohabitating for decades

Článek Loading… loading… The influence of download time on information search

Článek Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide

Článek Echolocation while drinking: Pulse-timing strategies by high- and low-frequency FM bats

Článek A novel one-class classification approach to accurately predict disease-gene association in acute myeloid leukemia cancer

Článek Characterization and quantitative trait locus mapping of late-flowering from a Thai soybean cultivar introduced into a photoperiod-insensitive genetic background

Článek Plasmodium falciparum infection dysregulates placental autophagy

Článek Intraocular pressure elevation after subtenon triamcinolone acetonide injection; Multicentre retrospective cohort study in Japan

Článek Generalized nonlinear Schrödinger equations describing the Second Harmonic Generation of femtosecond pulse, containing a few cycles, and their integrals of motion

Článek Community perception of abortion, women who abort and abortifacients in Kisumu and Nairobi counties, Kenya

Článek Expression of Concern: Synthesized multiple antigenic polypeptide vaccine based on B-cell epitopes of human heparanase could elicit a potent antimetastatic effect on human hepatocellular carcinoma in vivo

Článek The Salmonella type III effector SpvC triggers the reverse transmigration of infected cells into the bloodstream

Článek Spatial patterns of tuberculosis and HIV co-infection in Ethiopia

Článek Serum PCSK6 and corin levels are not associated with cardiovascular outcomes in patients undergoing coronary angiography

Článek On a remarkable sexual dimorphic trait in the Characiformes related to the olfactory organ and description of a new miniature species of Tyttobrycon Géry (Characiformes: Characidae)

Článek Effect of integrating a video intervention on parenting practices and related parental self-efficacy regarding health behaviours within the Feel4Diabetes-study in Belgian primary schoolchildren from vulnerable families: A cluster randomized trial

Článek Type 2 diabetes care: Improvement by standardization at a diabetes rehabilitation clinic. An observational report

Článek Regulating pharmacists as contraception providers: A qualitative study from Coastal Kenya on injectable contraception provision to youth

Článek The impact of familial risk and early life adversity on emotion and reward processing networks in youth at-risk for bipolar disorder

Článek Melanism evolution in the cat family is influenced by intraspecific communication under low visibility

Článek Gene expression profiles classifying clinical stages of tuberculosis and monitoring treatment responses in Ethiopian HIV-negative and HIV-positive cohorts

Článek Selection of valid reference genes for quantitative real-time PCR in Cotesia chilonis (Hymenoptera: Braconidae) exposed to different temperatures

Článek Magnitude of surgical site infection and its associated factors among patients who underwent a surgical procedure at Wolaita Sodo University Teaching and Referral Hospital, South Ethiopia

Článek Kyasanur Forest Disease vaccination coverage and its perceived barriers in Goa, India—A mixed methods operational research

Článek Maternal psychosocial risk factors and lower respiratory tract infection (LRTI) during infancy in a South African birth cohort

Článek Ameliorating effects of Gö6976, a pharmacological agent that inhibits protein kinase D, on collagen-induced arthritis

Článek Regional hypothermia improves gastric microcirculatory oxygenation during hemorrhage in dogs

Článek Dynamical comparison between Drosha and Dicer reveals functional motion similarities and dissimilarities

Článek Retraction: Circulating FoxP3+ regulatory T and interleukin17-producing Th17 cells actively influence HBV clearance in de novo Hepatitis B virus infected patients after orthotopic liver transplantation

Článek Correction: Data in question: A survey of European biobank professionals on ethical, legal and societal challenges of biobank research

Článek Expression of HIF-1α is related to a poor prognosis and tamoxifen resistance in contralateral breast cancer

Článek Metabolic responses of wheat seedlings to osmotic stress induced by various osmolytes under iso-osmotic conditions

Článek A δ2H Isoscape of blackberry as an example application for determining the geographic origins of plant materials in New Zealand

Článek Fiber visualization for preoperative glioma assessment: Tractography versus local connectivity mapping

Článek Amiselimod (MT-1303), a novel sphingosine 1-phosphate receptor-1 functional antagonist, inhibits progress of chronic colitis induced by transfer of CD4+CD45RBhigh T cells

Článek Insights of organic fertilizer micro flora of bovine manure and their useful potentials in sustainable agriculture

Článek A scalable culturing system for the marine annelid Platynereis dumerilii

Článek Is parity a cause of tooth loss? Perceptions of northern Nigerian Hausa women

Článek Low-diversity bacterial microbiota in Southern Ocean representatives of lanternfish genera Electrona, Protomyctophum and Gymnoscopelus (family Myctophidae)

Článek Bacteriologically-confirmed pulmonary tuberculosis in an Ethiopian prison: Prevalence from screening of entrant and resident prisoners

Článek Multi-objective AGV scheduling in an automatic sorting system of an unmanned (intelligent) warehouse by using two adaptive genetic algorithms and a multi-adaptive genetic algorithm

Článek Identification of novel non-myelin biomarkers in multiple sclerosis using an improved phage-display approach

Článek PTH1-34 improves bone healing by promoting angiogenesis and facilitating MSCs migration and differentiation in a stabilized fracture mouse model

Článek Micro-RNA signatures in monozygotic twins discordant for congenital heart defects

Článek Aspirin enhances sensitization to the egg-white allergen ovalbumin in rats

Článek HCV incidence is associated with injecting partner age and HCV serostatus mixing in young adults who inject drugs in San Francisco

Článek Adherence is associated with a favorable outcome after lung transplantation

Článek Selection and validation of reference genes desirable for gene expression analysis by qRT-PCR in MeJA-treated ginseng hairy roots

Článek Availability, prices and affordability of essential medicines for treatment of diabetes and hypertension in private pharmacies in Zambia

Článek Amnestic mild cognitive impairment in Parkinson’s disease: White matter structural changes and mechanisms

Článek Menagerie: A text-mining tool to support animal-human translation in neurodegeneration research

Článek Profusion of G-quadruplexes on both subunits of metazoan ribosomes

Článek Analysis of genome-wide DNA arrays reveals the genomic population structure and diversity in autochthonous Greek goat breeds

Článek Impact of human-derived hemoglobin based oxygen vesicles as a machine perfusion solution for liver donation after cardiac death in a pig model

Článek Microbial diversity within the digestive tract contents of Dezhou donkeys

Článek Nexrutine and exercise similarly prevent high grade prostate tumors in transgenic mouse model

Článek Shannon entropy approach reveals relevant genes in Alzheimer’s disease

Článek Experimental hut evaluation of DawaPlus 3.0 LN and DawaPlus 4.0 LN treated with deltamethrin and PBO against free-flying populations of Anopheles gambiae s.l. in Vallée du Kou, Burkina Faso

Článek Induction of miR 21 impairs the anti-Leishmania response through inhibition of IL-12 in canine splenic leukocytes

Článek Ultra-deep massively parallel sequencing with unique molecular identifier tagging achieves comparable performance to droplet digital PCR for detection and quantification of circulating tumor DNA from lung cancer patients

Článek Pupillometry evaluation of melanopsin retinal ganglion cell function and sleep-wake activity in pre-symptomatic Alzheimer’s disease

Článek Sickness absence and disability pension before and after first childbirth and in nulliparous women by numerical gender segregation of occupations: A Swedish population-based longitudinal cohort study

Článek New insights into intranuclear inclusions in thyroid carcinoma: Association with autophagy and with BRAFV600E mutation

Článek Effects of medium chain triglycerides supplementation on insulin sensitivity and beta cell function: A feasibility study

Článek The impact of mental health recovery narratives on recipients experiencing mental health problems: Qualitative analysis and change model

Článek Not so unique to Primates: The independent adaptive evolution of TRIM5 in Lagomorpha lineage

Článek Distributed forecasting and ant colony optimization for the bike-sharing rebalancing problem with unserved demands

Článek Chronic dietary supplementation with kynurenic acid, a neuroactive metabolite of tryptophan, decreased body weight without negative influence on densitometry and mandibular bone biomechanical endurance in young rats

Článek Higher neuron densities in the cerebral cortex and larger cerebellums may limit dive times of delphinids compared to deep-diving toothed whales

Článek Individual variation in migratory movements of chinstrap penguins leads to widespread occupancy of ice-free winter habitats over the continental shelf and deep ocean basins of the Southern Ocean

Článek Correction: Anabolic steroids among resistance training practitioners

Článek Correction: Incidence of sexually transmitted infections in men who have sex with men and who are at substantial risk of HIV infection – A meta-analysis of data from trials and observational studies of HIV pre-exposure prophylaxis

Článek Retraction: Multidrug-Resistance Related Long Non-Coding RNA Expression Profile Analysis of Gastric Cancer

Článek The effect of emotional information from eyes on empathy for pain: A subliminal ERP study

Článek NKL homeobox gene activities in normal and malignant myeloid cells

Článek Personal distress as a mediator between self-esteem, self-efficacy, loneliness and problematic video gaming in female and male emerging adult gamers

Článek Prevalence of vitamin D deficiency in women from southern Brazil and association with vitamin D-binding protein levels and GC-DBP gene polymorphisms

Článek Balance control mechanisms do not benefit from successive stimulation of different sensory systems

Článek Measuring individual differences in cognitive abilities in the lab and on the web

Článek Correction: Improving the impact of HIV pre-exposure prophylaxis implementation in small urban centers among men who have sex with men: An agent-based modelling study

Článek Objective sleep assessment in >80,000 UK mid-life adults: Associations with sociodemographic characteristics, physical activity and caffeine

Článek Self-reported traffic-related air pollution and respiratory symptoms among adults in an area with modest levels of traffic

Článek A hierarchical loss and its problems when classifying non-hierarchically

Článek Cross-cultural examination of the Big Five Personality Trait Short Questionnaire: Measurement invariance testing and associations with mental health

Článek A geographically weighted random forest approach for evaluate forest change drivers in the Northern Ecuadorian Amazon

Článek Spatial genetic structure and diversity of natural populations of Aesculus hippocastanum L. in Greece

Článek Anemia in patients with diabetic foot ulcer and its impact on disease outcome among Nigerians: Results from the MEDFUN study

Článek The effectiveness of physiotherapy interventions on pain and quality of life in adults with persistent post-surgical pain compared to usual care: A systematic review

Článek Association between anxiety and non-coding genetic variants of the galanin neuropeptide

Článek Evaluating the effectiveness of HOCl application on odor reduction and earthworm population growth during vermicomposting of food waste employing Eisenia fetida

Článek What is known about the quality of out-of-hospital emergency medical services in the Arabian Gulf States? A systematic review

Článek Impact of dietary patterns, individual and workplace characteristics on blood pressure status among civil servants in Bida and Wushishi communities of Niger State, Nigeria

Článek Robust detection of event-related potentials in a user-voluntary short-term imagery task

Článek Microbiota composition of the dorsal patch of reproductive male Leptonycteris yerbabuenae

Článek Characteristics of the gut microbiota in professional martial arts athletes: A comparison between different competition levels

Článek Interpreting social determinants: Emergent properties and adolescent risk behaviour

Článek Tulathromycin treatment does not affect bacterial dissemination or clearance of Brucella melitensis 16M following experimental infection of goats

Článek Hydrogenotrophic methanogens of the mammalian gut: Functionally similar, thermodynamically different—A modelling approach

Článek Gene delivery of a modified antibody to Aβ reduces progression of murine Alzheimer’s disease

Článek Flock sensitivity and specificity of pooled fecal qPCR and pooled serum ELISA for screening ovine paratuberculosis

Článek Disrupted resting-state brain functional network in methamphetamine abusers: A brain source space study by EEG

Článek Steady expression of high oleic acid in peanut bred by marker-assisted backcrossing for fatty acid desaturase mutant alleles and its effect on seed germination along with other seedling traits

Článek DNA metabarcoding-based diet survey for the Eurasian otter (Lutra lutra): Development of a Eurasian otter-specific blocking oligonucleotide for 12S rRNA gene sequencing for vertebrates

Článek Dynamics of photosynthetic responses in 10 rubber tree (Hevea brasiliensis) clones in Colombian Amazon: Implications for breeding strategies

Článek Inferring disease severity in rheumatoid arthritis using predictive modeling in administrative claims databases

Článek An evaluation of different classification algorithms for protein sequence-based reverse vaccinology prediction

Článek Detecting false intentions using unanticipated questions

Článek In vitro activity and In vivo efficacy of Isoliquiritigenin against Staphylococcus xylosus ATCC 700404 by IGPD target

Článek When risk becomes illness: The personal and social consequences of cervical intraepithelial neoplasia medical surveillance

Článek Sperm DNA integrity in adult survivors of paediatric leukemia and lymphoma: A pilot study on the impact of age and type of treatment

Článek Swaying slower reduces the destabilizing effects of a compliant surface on voluntary sway dynamics

Článek Dye diffusion during laparoscopic tubal patency tests may suggest a lymphatic contribution to dissemination in endometriosis: A prospective, observational study

Článek Intra-individual correlations between quantitative THK-5351 PET and MRI-derived cortical volume in Alzheimer’s disease differ according to disease severity and amyloid positivity

Článek Assessment of the role of Trichomonas tenax in the etiopathogenesis of human periodontitis: A systematic review

Článek Root and alveolar bone changes in first premolars adjacent to the traction of buccal versus palatal maxillary impacted canines

Článek Investigating multisite pain as a predictor of self-reported falls and falls requiring health care use in an older population: A prospective cohort study

Článek The socio-economic status gradient in median lifespan by birth cohorts: Evidence from Dutch Olympic athletes born between 1852 and 1947

Článek Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening

Článek Brief group-delivered motivational interviewing is equally effective as brief group-delivered cognitive-behavioral therapy at reducing alcohol use in risky college drinkers

Článek Predicting the occurrence of surgical site infections using text mining and machine learning

Článek Organic carbon sequestration in sediments of subtropical Florida lakes

Článek Reliability of isokinetic knee strength measurements in children: A systematic review and meta-analysis

Článek Plasma concentration of neurofilament light chain protein decreases after switching from tenofovir disoproxil fumarate to tenofovir alafenamide fumarate

Článek Revealing the assembly of filamentous proteins with scanning transmission electron microscopy

Článek Effects of treated wastewater on the ecotoxicity of small streams – Unravelling the contribution of chemicals causing effects

Článek Air quality and obesity at older ages in China: The role of duration, severity and pollutants

Článek Breeding French bulldogs so that they breathe well—A long way to go

Článek A network-centric approach for estimating trust between open source software developers

Článek A novel scoring system to predict the requirement for surgical intervention in victims of motor vehicle crashes: Development and validation using independent cohorts

Článek Prediction of overt hepatic encephalopathy by the continuous reaction time method and the portosystemic encephalopathy syndrome test in clinically mentally unimpaired patients with cirrhosis

Článek Attentional capture by Pavlovian reward-signalling distractors in visual search persists when rewards are removed

Článek Validation of risk factors for recurrence of renal cell carcinoma: Results from a large single-institution series

Článek Real world, big data cost of pharmaceutical treatment for rheumatoid arthritis in Greece

Článek Does training with amplitude modulated tones affect tone-vocoded speech perception?

Článek Accuracy of the Cosmed K5 portable calorimeter

Článek Non-invasive diagnostic criteria of hepatocellular carcinoma: Comparison of diagnostic accuracy of updated LI-RADS with clinical practice guidelines of OPTN-UNOS, AASLD, NCCN, EASL-EORTC, and KLSCG-NCC

Článek Omentin-1 in diabetes mellitus: A systematic review and meta-analysis

Článek Immunological recovery, failure and factors associated with CD-4 T-cells progression over time, among adolescents and adults living with HIV on Antiretroviral Therapy in Northern Ethiopia: A retrospective cross sectional study

Článek Correction: Examining the relationship between socio-economic status, WASH practices and wasting

Článek Prediction of poor outcome after hypoxic-ischemic brain injury by diffusion-weighted imaging: A systematic review and meta-analysis

Článek Correction: Change in left inferior frontal connectivity with less unexpected harmonic cadence by musical expertise

Článek Absence of posture-dependent and posture-congruent memory effects on the recall of action sentences

Článek Identifiability and numerical algebraic geometry

Článek Co-infection of cattle with Fasciola hepatica or F. gigantica and Mycobacterium bovis: A systematic review

Článek High maternal self-efficacy is associated with meeting Institute of Medicine gestational weight gain recommendations

Článek Isolation of endothelial cells, pericytes and astrocytes from mouse brain

Článek Effects of metformin administration on endocrine-metabolic parameters, visceral adiposity and cardiovascular risk factors in children with obesity and risk markers for metabolic syndrome: A pilot study

Článek Physiological impact of nanoporous acupuncture needles: Laser Doppler perfusion imaging in healthy volunteers

Článek A world map of evidence-based medicine: Density equalizing mapping of the Cochrane database of systematic reviews

Článek Common trust and personal safety issues: A systematic review on the acceptability of health and social interventions for persons with lived experience of homelessness

Článek Implications of monocular vision for racing drivers

Článek Effect of arteriovenous access closure and timing on kidney function in kidney transplant recipients

Článek Expression of Concern: Activation of Notch Signaling Is Required for Cholangiocarcinoma Progression and Is Enhanced by Inactivation of p53 In Vivo

Článek Correction: Calorie information and dieting status modulate reward and control activation during the evaluation of food images

Článek Immune responses to a HSV-2 polynucleotide immunotherapy COR-1 in HSV-2 positive subjects: A randomized double blinded phase I/IIa trial

Článek What Twitter teaches us about patient-provider communication on pain

Článek Development of a computer-aided design software for the quantitative evaluation of aesthetic damage

Článek Microtubules are necessary for proper Reticulon localization during mitosis

Článek Human perception and biosignal-based identification of posed and spontaneous smiles

Článek State of household need for caregivers and determinants of psychological burden among caregivers of older people in Thailand: An analysis from national surveys on older persons

Článek Dietary habits of the black-necked swan Cygnus melancoryphus (Birds: Anatidae) and variability of the aquatic macrophyte cover in the Río Cruces wetland, southern Chile

Článek Improving emotional health and self-esteem of Malaysian adolescents living in orphanages through Life Skills Education program: A multi-centre randomized control trial

Článek Radiocarbon, Bayesian chronological modeling and early European metal circulation in the sixteenth-century AD Mohawk River Valley, USA

Článek Economic evaluation of HPV DNA test as primary screening method for cervical cancer: A health policy discussion in Greece

Článek Clonality testing in the lymph nodes from dogs with lymphadenomegaly due to Leishmania infantum infection

Článek Transcriptome landscape of Rafflesia cantleyi floral buds reveals insights into the roles of transcription factors and phytohormones in flower development

Článek Comparison of 6-week PMTCT outcomes for HIV-exposed and HIV-unexposed infants in the era of lifelong ART: Results from an observational prospective cohort study

Článek Sex differences in physical performance by age, educational level, ethnic groups and birth cohort: The Longitudinal Aging Study Amsterdam

Článek HIV-1 proteins gp120 and tat induce the epithelial–mesenchymal transition in oral and genital mucosal epithelial cells

Článek Correction: Intraperitoneal administration of follistatin promotes adipocyte browning in high-fat diet-induced obese mice

Článek Inflammatory mediators and lung abnormalities in HIV: A systematic review

Článek An investigation of machine learning methods in delta-radiomics feature analysis

Článek Differences in receipt of opioid agonist treatment and time to enter treatment for opioid use disorder among specialty addiction programs in the United States, 2014-17

Článek Intensity-modulated ventricular irradiation for intracranial germ-cell tumors: Survival analysis and impact of salvage re-irradiation

Článek Personalized breast cancer screening strategies: A systematic review and quality assessment

Článek The shifting epidemiology and serotype distribution of invasive pneumococcal disease in Ontario, Canada, 2007-2017

Článek Backwashing performance of self-cleaning screen filters in drip irrigation systems

Článek Hierarchical cluster analysis to identify the homogeneous desertification management units

Článek MicroRNA-710 regulates multiple pathways of carcinogenesis in murine metastatic breast cancer

Článek MicroRNA profiling in canine multicentric lymphoma

Článek Early impact of agropastoral activities and climate on the littoral landscape of Corsica since mid-Holocene

Článek Barriers and facilitators for caregiver involvement in the home care of people with pressure injuries: A qualitative study

Článek Evaluating mob stocking for beef cattle in a temperate grassland

Článek Suicide among physicians and health-care workers: A systematic review and meta-analysis

Článek Survival kinetics of Listeria monocytogenes on chickpeas, sesame seeds, pine nuts, and black pepper as affected by relative humidity storage conditions

Článek Free thiol groups on poly(aspartamide) based hydrogels facilitate tooth-derived progenitor cell proliferation and differentiation

Článek Acute and chronic traumatic diaphragmatic hernia: 10 years’ experience

Článek Application of DArT seq derived SNP tags for comparative genome analysis in fishes; An alternative pipeline using sequence data from a non-traditional model species, Macquaria ambigua

Článek Dipole-wind interactions under gap wind jet conditions in the Gulf of Tehuantepec, Mexico: A surface drifter and satellite database analysis

Článek PfmPif97-like regulated by Pfm-miR-9b-5p participates in shell formation in Pinctada fucata martensii

Článek Synapsin 1 promotes Aβ generation via BACE1 modulation

Článek Predictive utility of the C-reactive protein to albumin ratio in early allograft dysfunction in living donor liver transplantation: A retrospective observational cohort study

Článek Effects of SCUBA bubbles on counts of roving piscivores in a large remote marine protected area

Článek Examining practice effects in repeated measurements of vibration perception thresholds on finger pulps of healthy individuals – Is it possible to improve your results over a clinically relevant test interval?

Článek Analysis of gut microbiota of obese individuals with type 2 diabetes and healthy individuals

Článek The evaluation of AMSR-E soil moisture data in atmospheric modeling using a suitable time series iteration to derive land surface fluxes over the Tibetan Plateau

Článek Comparison of plasma fatty acid binding protein 4 concentration in venous and capillary blood

Článek Nonalcoholic fatty liver disease and hepatic fibrosis among perinatally HIV-monoinfected Asian adolescents receiving antiretroviral therapy

Článek Environmental enrichment effects after early stress on behavior and functional brain networks in adult rats

Článek Correction: Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies

Článek Developmental expression of human tau in Drosophila melanogaster glial cells induces motor deficits and disrupts maintenance of PNS axonal integrity, without affecting synapse formation

Článek TRPC3 determines osmosensitive [Ca2+]i signaling in the collecting duct and contributes to urinary concentration

Článek Correction: May the change of platelet to lymphocyte ratio be a prognostic factor for T3-T4 laryngeal squamous cell carcinoma: A retrospective study

Článek Awareness, willingness to use, and history of HIV PrEP use among gay, bisexual, and other men who have sex with men in Nigeria

Článek Odor quality profile is partially influenced by verbal cues

Článek A novel assessment for Readiness Evaluation during Simulated Dismounted Operations: A reliability study

Článek Cognitive bias modification for energy drink cues

Článek Contribution of ROS and metabolic status to neonatal and adult CD8+ T cell activation

Článek Correction: Assessment of lung function in successfully treated tuberculosis reveals high burden of ventilatory defects and COPD

Článek Verification of mesenchymal stem cell injection therapy for interstitial cystitis in a rat model

Článek Vertical transmission of HIV among pregnant women who initially had false–negative rapid HIV tests in four South African antenatal clinics

Článek Tapped out or barely tapped? Recommendations for how to harness the vast and largely unused potential of the Mechanical Turk participant pool

Článek Are lizards sensitive to anomalous seasonal temperatures? Long-term thermobiological variability in a subtropical species

Článek Mutation spectrums of TSC1 and TSC2 in Chinese women with lymphangioleiomyomatosis (LAM)

Článek “That’s all Fake”: Health professionals stigma and physical healthcare of people living with Serious Mental Illness

Článek On the interpretation of the atmospheric mechanism transporting the environmental trigger of Kawasaki Disease

Článek Comparison of the Panther Fusion and Allplex assays for the detection of respiratory viruses in clinical samples

Článek Acute kidney injury in Ugandan children with severe malaria is associated with long-term behavioral problems

Článek Rho-associated kinase and zipper-interacting protein kinase, but not myosin light chain kinase, are involved in the regulation of myosin phosphorylation in serum-stimulated human arterial smooth muscle cells

Článek Use of detailed family history data to improve risk prediction,with application to breast cancer screening

Článek The promise of open survey questions—The validation of text-based job satisfaction measures

Článek Measuring within-day cognitive performance using the experience sampling method: A pilot study in a healthy population

Článek Shifts in trait-based and taxonomic macrofauna community structure along a 27-year time-series in the south-eastern North Sea

Článek Plasma biomarkers of inflammation, coagulation, and brain injury as predictors of delirium duration in older hospitalized patients

Článek Factors associated with repeat rectal Neisseria gonorrhoeae and Chlamydia trachomatis screening following inconclusive nucleic acid amplification testing: A potential missed opportunity for screening

Článek Beyond Buddhism and animism: A psychometric test of the structure of Burmese Theravada Buddhism

Článek Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases

Článek Assessment of the perceived safety culture in the petrochemical industry in Japan: A cross-sectional study

Článek The Intersection of Human Disturbance and Diel Activity, with Potential Consequences on Trophic Interactions

Článek Levels of caspase-3 and histidine-rich glycoprotein in the embryo secretome as biomarkers of good-quality day-2 embryos and high-quality blastocysts

Článek Improving accuracy for finite element modeling of endovascular coiling of intracranial aneurysm

Článek Drought stress and re-watering affect the abundance of TIP aquaporin transcripts in barley

Článek Intra- and inter-task reliability of spatial attention measures in healthy older adults

Článek Genome-wide comparisons of gene expression in adult versus elderly burn patients

Článek Challenges to generating political prioritization for adolescent sexual and reproductive health in Kenya: A qualitative study

Článek Chronic atrophic gastritis and intestinal metaplasia surrounding diffuse-type gastric cancer: Are they just bystanders in the process of carcinogenesis?

Článek GLAMbox: A Python toolbox for investigating the association between gaze allocation and decision behaviour

Článek Correction: Rapid visual categorization is not guided by early salience-based selection

Článek Oxygen inhalation improves postoperative survival in ketamine-xylazine anaesthetised rats: An observational study

Článek An inter-island comparison of Darwin’s finches reveals the impact of habitat, host phylogeny, and island on the gut microbiome

Článek The use of opioids in low acuity pediatric trauma patients

Článek The acute myeloid leukemia associated AML1-ETO fusion protein alters the transcriptome and cellular progression in a single-oncogene expressing in vitro induced pluripotent stem cell based granulocyte differentiation model

Článek Primary Epstein-Barr virus infection with and without infectious mononucleosis

Článek “Disruptive behavior” in the operating room: A prospective observational study of triggers and effects of tense communication episodes in surgical teams

Článek Measuring affect-related cognitive bias: Do mice in opposite affective states react differently to negative and positive stimuli?

Článek Impaired cardiac performance, protein synthesis, and mitochondrial function in tumor-bearing mice

Článek Determinants of speeding among new generations of car drivers from the Arabian Peninsula. An investigation based among Omani drivers using the theory of planned behaviour

Článek Modulation of protective reflex cough by acute immune driven inflammation of lower airways in anesthetized rabbits

Článek KRAS and NRAS mutational gene profile of metastatic colorectal cancer patients in Jordan

Článek Successional, spatial, and seasonal changes in seed rain in the Atlantic forest of southern Bahia, Brazil

Článek Ultrasound microbubble potentiated enhancement of hyperthermia-effect in tumours

Článek Introgression of a cry1Ab transgene into open pollinated maize and its effect on Cry protein concentration and target pest survival

Článek Benefits of VISION Max automated cross-matching in comparison with manual cross-matching: A multidimensional analysis

Článek An explorative study identifies miRNA signatures for the diagnosis of non-celiac wheat sensitivity

Článek Effects of long-term statin-treatment on coronary atherosclerosis in patients with inflammatory joint diseases

Článek Connectivity differences between Gulf War Illness (GWI) phenotypes during a test of attention

Článek Native speakers like affixes, L2 speakers like letters? An overt visual priming study investigating the role of orthography in L2 morphological processing

Článek A partial genome assembly of the miniature parasitoid wasp, Megaphragma amalphitanum

Článek Can we learn from the ecology of the Bohemian gentian and save another closely related species of Gentianella?

Článek Are we prepared? The development of performance indicators for public health emergency preparedness using a modified Delphi approach

Článek Racial discrimination in medical care settings and opioid pain reliever misuse in a U.S. cohort: 1992 to 2015

Článek Applying circuit theory and landscape linkage maps to reintroduction planning for California Condors

Článek An improved understanding of ungulate population dynamics using count data: Insights from western Montana

Článek Pediatric trainees systematically under-report duty hour violations compared to electronic health record defined shifts

Článek An exclusive human milk diet for very low birth weight newborns—A cost-effectiveness and EVPI study for Germany

Článek Investigating unexplained genetic variation and its expression in the arbuscular mycorrhizal fungus Rhizophagus irregularis: A comparison of whole genome and RAD sequencing data

Článek Disease activity and damage in patients with primary Sjogren’s syndrome: Prognostic value of salivary gland ultrasonography

Článek A low-loss and compact single-layer butler matrix for a 5G base station antenna

Článek Response of rhizosphere bacterial community of Taxus chinensis var. mairei to temperature changes

Článek Choosing and enjoying violence in narratives

Článek Phylogeography, genetic diversity, and population structure of Nile crocodile populations at the fringes of the southern African distribution

Článek Association between workplace bullying and burnout, professional quality of life, and turnover intention among clinical nurses

Článek Factors predictive of the success of tuberculosis treatment: A systematic review with meta-analysis

Článek Area extraction and spatiotemporal characteristics of winter wheat–summer maize in Shandong Province using NDVI time series

Článek Caring for the elderly: A person-centered segmentation approach for exploring the association between health care needs, mental health care use, and costs in Germany

Článek Potentially inappropriate medication in older participants of the Berlin Aging Study II (BASE-II) – Sex differences and associations with morbidity and medication use

Článek Previously implanted mitral surgical prosthesis in patients undergoing transcatheter aortic valve implantation: Procedural outcome and morphologic assessment using multidetector computed tomography

Článek Towards elimination of measles and rubella in Italy: Progress and challenges

Článek Molecular characterization of pulmonary defenses against bacterial invasion in allergic asthma: The role of Foxa2 in regulation of β-defensin 1

Článek A validation of machine learning-based risk scores in the prehospital setting

Článek Early life starvation has stronger intra-generational than transgenerational effects on key life-history traits and consumption measures in a sawfly

Článek Longitudinal changes in plasma hemopexin and alpha-1-microglobulin concentrations in women with and without clinical risk factors for pre-eclampsia

Článek Feasibility of thin-slice abdominal CT in overweight patients using a vendor neutral image-based denoising algorithm: Assessment of image noise, contrast, and quality

Článek Women's abortion seeking behavior under restrictive abortion laws in Mexico

Článek Understanding the combining ability for physiological traits in soybean

Článek Second language learning induces grey matter volume increase in people with multiple sclerosis

Článek Increased performance of DNA metabarcoding of macroinvertebrates by taxonomic sorting

Článek Hybrid denture acrylic composites with nanozirconia and electrospun polystyrene fibers

Článek Predictive sampling effort and species-area relationship models for estimating richness in fragmented landscapes

Článek The mixture toxicity of heavy metals on Photobacterium phosphoreum and its modeling by ion characteristics-based QSAR

Článek Exogenous melatonin reduces the inhibitory effect of osmotic stress on photosynthesis in soybean

Článek Comparative analysis of ascorbate peroxidases (APXs) from selected plants with a special focus on Oryza sativa employing public databases

Článek The microbiota composition of the offspring of patients with gestational diabetes mellitus (GDM)

Článek Analysis of 13,312 benthic invertebrate samples from German streams reveals minor deviations in ecological status class between abundance and presence/absence data

Článek Extending the use of the World Health Organisations’ water sanitation and hygiene assessment tool for surveys in hospitals – from WASH-FIT to WASH-FAST

Článek Measuring subjective social status in children of diverse societies

Článek The effect of gut passage by waterbirds on the seed coat and pericarp of diaspores lacking “external flesh”: Evidence for widespread adaptation to endozoochory in angiosperms

Článek Cost effectiveness of therapeutic drug monitoring for imatinib administration in chronic myeloid leukemia

Článek Tissue ACE phenotyping in lung cancer

Článek Risk factors in the illness-death model: Simulation study and the partial differential equation about incidence and prevalence

Článek Association of cord blood methylation with neonatal leptin: An epigenome wide association study

Článek Clonality, spatial structure, and pathogenic variation in Fusarium fujikuroi from rain-fed rice in southern Laos

Článek Effect of Iodine treatments on Ocimum basilicum L.: Biofortification, phenolics production and essential oil composition

Článek In Vitro detection of Chronic Wasting Disease (CWD) prions in semen and reproductive tissues of white tailed deer bucks (Odocoileus virginianus)

Článek Thermodilution vs estimated Fick cardiac output measurement in an elderly cohort of patients: A single-centre experience

Článek Association between depressive symptoms and poor sleep quality among Han and Manchu ethnicities in a large, rural, Chinese population

Článek Application of pharmacogenomics and bioinformatics to exemplify the utility of human ex vivo organoculture models in the field of precision medicine

Článek Adherence to dietary guidelines for the Spanish population and risk of overweight/obesity in the SUN cohort

Článek Impact on mortality of being seropositive for hepatitis C virus antibodies among blood donors in Brazil: A twenty-year study

Článek Dietary intake as a predictor for all-cause mortality in hemodialysis subjects (NUGE-HD study)

Článek Rats’ (Rattus norvegicus) tool manipulation ability exceeds simple patterned behavior

Článek Luminescent and fluorescent triple reporter plasmid constructs for Wnt, Hedgehog and Notch pathway

Článek A lab-on-a-chip for rapid miRNA extraction

Článek Ghost hunting in the nonlinear dynamic machine

Článek Dysregulation of sterol regulatory element-binding protein 2 gene in HIV treatment-experienced individuals

Článek Evaluation of bacteriophage as an adjunct therapy for treatment of peri-prosthetic joint infection caused by Staphylococcus aureus

Článek Neuronal and glial DNA methylation and gene expression changes in early epileptogenesis

Článek Kinetics of the thermal inactivation and the refolding of bacterial luciferases in Bacillus subtilis and in Escherichia coli differ

Článek The use of back propagation neural networks and 18F-Florbetapir PET for early detection of Alzheimer’s disease using Alzheimer’s Disease Neuroimaging Initiative database

Článek Refinement of metabolite detection in cystic fibrosis sputum reveals heme correlates with lung function decline

Článek Labeling surface proteins with high specificity: Intrinsic limitations of phosphopantetheinyl transferase systems

Článek Irradiation dose response under hypoxia for the application of the sterile insect technique in Drosophila suzukii

Článek Neutrophils remain detrimentally active in hydroxyurea-treated patients with sickle cell disease

Článek Correction: Enhancing genomic selection by fitting large-effect SNPs as fixed effects and a genotype-by-environment effect using a maize BC1F3:4population

Článek Binding and functional profiling of antibody mutants guides selection of optimal candidates as antibody drug conjugates

Článek DUSTBot: A duplex and stealthy P2P-based botnet in the Bitcoin network

Článek Force-stabilizing synergies can be retained by coordinating sensory-blocked and sensory-intact digits

Článek Temperature time series analysis at Yucatan using natural and horizontal visibility algorithms

Článek Genome-wide identification and expression profile of the MADS-box gene family in Erigeron breviscapus

Článek Evaluating the international standards gap for the use of acupuncture needles by physiotherapists and chiropractors: A policy analysis

Článek Analyses with double knockouts of the Bmpr1a and Bmpr1b genes demonstrate that BMP signaling is involved in the formation of precerebellar mossy fiber nuclei derived from the rhombic lip

Článek The protein architecture in Bacteria and Archaea identifies a set of promiscuous and ancient domains

Článek Utility of preoperative electrophysiological testing of the facial nerve in patients with vestibular schwannoma

Článek Dynamics of plasma micronutrient concentrations and their correlation with serum proteins and thyroid hormones in patients with paracoccidioidomycosis

Článek Equity in aid allocation and distribution: A qualitative study of key stakeholders in Northern Uganda

Článek Health-related quality of life and intensity-specific physical activity in high-risk adults attending a behavior change service within primary care

Článek Syphilis among adult males with a history of male-to-male sexual contact living with diagnosed HIV in New York State (excluding New York City): The challenge of intersecting epidemics

Článek Entropy of human leukocyte antigen and killer-cell immunoglobulin-like receptor systems in immune-mediated disorders: A pilot study on multiple sclerosis

Článek Insights into fungal diversity of a shallow-water hydrothermal vent field at Kueishan Island, Taiwan by culture-based and metabarcoding analyses

Článek Predicting Abundances of Aedes mcintoshi, a primary Rift Valley fever virus mosquito vector

Článek Self-association of human beta-galactocerebrosidase: Dependence on pH, salt, and surfactant

Článek Lowbush blueberry fruit yield and growth response to inorganic and organic N-fertilization when competing with two common weed species

Článek Copy number-based quantification assay for non-invasive detection of PVT1-derived transcripts

Článek Association between religiosity and depression varies with age and sex among adults in South America: Evidence from the CESCAS I study

Článek Recall accuracy of weekly automated surveys of health care utilization and infectious disease symptoms among infants over the first year of life

Článek Physiological response of North China red elder container seedlings to inoculation with plant growth-promoting rhizobacteria under drought stress

Článek Acute kidney injury – A frequent and serious complication after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction

Článek Neurotherapeutic effects of Ginkgo biloba extract and its terpene trilactone, ginkgolide B, on sciatic crush injury model: A new evidence

Článek Clinical utility of mono-exponential model diffusion weighted imaging using two b-values compared to the bi- or stretched exponential model for the diagnosis of biliary atresia in infant liver MRI

Článek Optical coherence tomography angiography reveals progressive worsening of retinal vascular geometry in diabetic retinopathy and improved geometry after panretinal photocoagulation

Článek Comparison of standard and alternative methods for chest compressions in a single rescuer infant CPR: A prospective simulation study

Článek Characterization of the physical properties of electron-beam-irradiated white rice and starch during short-term storage

Článek Colonic bacterial composition is sex-specific in aged CD-1 mice fed diets varying in fat quality

Článek The nature of the ligand’s side chain interacting with the S1'-subsite of metallocarboxypeptidase T (from Thermoactinomyces vulgaris) determines the geometry of the tetrahedral transition complex

Článek Clarithromycin use and the risk of mortality and cardiovascular events: A systematic review and meta-analysis

Článek Droplet digital PCR assays for the quantification of brown trout (Salmo trutta) and Arctic char (Salvelinus alpinus) from environmental DNA collected in the water of mountain lakes

Článek Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene

Článek Estimation of membrane bending modulus of stiffness tuned human red blood cells from micropore filtration studies

Článek Retrospective analysis of central venous catheters in elective intracranial surgery - Is there any benefit?

Článek Clinical impact of visceral-to-subcutaneous fat ratio in patients with acute aortic dissection

Článek Correction: Are viral-infections associated with Ménière’s Disease? A systematic review and meta-analysis of molecular-markers of viral-infection in case-controlled observational studies of MD

Článek Epidemiology of cardiovascular diseases related admissions in a referral hospital in the South West region of Cameroon: A cross-sectional study in sub-Saharan Africa

Článek Tankyrase inhibition sensitizes cells to CDK4 blockade

Článek Spelling performance on the web and in the lab

Článek Heteroxanthin as a pigment biomarker for Gonyostomum semen (Raphidophyceae)

Článek Sexually transmitted founder HIV-1 viruses are relatively resistant to Langerhans cell-mediated restriction

Článek High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans

Článek Correction: Safety and efficacy of tacrolimus-coated silicone plates as an alternative to mitomycin C in a rabbit model of conjunctival fibrosis

Článek Correction: Uncertainty analysis of species distribution models

Článek Correction: Testosterone deficiency reduces the effects of late cardiac remodeling after acute myocardial infarction in rats

Článek Correction: Trends and predictors of mother-to-child transmission of HIV in an era of protocol changes: Findings from two large health facilities in North East Nigeria

Článek Habitat quality, configuration and context effects on roe deer fecundity across a forested landscape mosaic

Článek Recording behaviour of indoor-housed farm animals automatically using machine vision technology: A systematic review

Článek Correction: Influence of three artificial light sources on oviposition and half-life of the Black Soldier Fly, Hermetia illucens (Diptera: Stratiomyidae): Improving small-scale indoor rearing

Článek Lead-I ECG for detecting atrial fibrillation in patients attending primary care with an irregular pulse using single-time point testing: A systematic review and economic evaluation

Článek External validation of clinical prediction rules for complications and mortality following Clostridioides difficile infection

Článek Vitamin D deficiency at the time of delivery – Prevalence and risk of postpartum infections

Článek Changing perioperative prophylaxis during antibiotic therapy and iterative debridement for orthopedic infections?

Článek Tyrphostin AG490 reduces inflammation and fibrosis in neonatal obstructive nephropathy

Článek Evaluation of antibiotic susceptibility patterns of pathogens isolated from routine laboratory specimens at Ndola Teaching Hospital: A retrospective study

Článek Age-period-cohort analysis with a constant-relative-variation constraint for an apportionment of period and cohort slopes

Článek Early neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society

Článek Improving graphs of cycles approach to structural similarity of molecules

Článek Heterotrimeric G-alpha subunits Gpa11 and Gpa12 define a transduction pathway that control spore size and virulence in Mucor circinelloides

Článek Clinical outcome of admitted HIV/AIDS patients in Ethiopian tertiary care settings: A prospective cohort study

Článek How the size of the to-be-learned material influences the encoding and later retrieval of associative memories: A pupillometric assessment

Článek "Tremendous financial burden": Crowdfunding for organ transplantation costs in Canada

Článek Stochastically modeling multiscale stationary biological processes

Článek Distribution of aerophilous diatom communities associated with terrestrial green macroalgae in the South Shetland Islands, Maritime Antarctica

Článek An eye-tracking approach to Autonomous sensory meridian response (ASMR): The physiology and nature of tingles in relation to the pupil

Článek Structural diversity in the atomic resolution 3D fingerprint of the titin M-band segment

Článek AlleleProfileR: A versatile tool to identify and profile sequence variants in edited genomes

Článek Spike culture derived wheat (Triticum aestivum L.) variants exhibit improved resistance to multiple chemotypes of Fusarium graminearum

Článek N-acetyl cysteine attenuates oxidative stress and glutathione-dependent redox imbalance caused by high glucose/high palmitic acid treatment in pancreatic Rin-5F cells

Článek Neurofilaments in blood is a new promising preclinical biomarker for the screening of natural scrapie in sheep

Článek Comparative transcriptome reveals the potential modulation mechanisms of estradiol affecting ovarian development of female Portunus trituberculatus

Článek Determinants of Group B streptococcal virulence potential amongst vaginal clinical isolates from pregnant women

Článek Identification of QTLs for resistance to maize rough dwarf disease using two connected RIL populations in maize

Článek Retraction: Ramentaceone, a Naphthoquinone Derived from Drosera sp., Induces Apoptosis by Suppressing PI3K/Akt Signaling in Breast Cancer Cells

Článek Correction: Differences in energy and nutritional content of menu items served by popular UK chain restaurants with versus without voluntary menu labelling: A cross-sectional study

Článek Correction: Cross-presentation of a spread-defective MCMV is sufficient to prime the majority of virus-specific CD8+ T cells

Článek Correction: An observational study comparing HPV prevalence and type distribution between HPV-vaccinated and -unvaccinated girls after introduction of school-based HPV vaccination in Norway

Článek Aortic pressure and forward and backward wave components in children, adolescents and young-adults: Agreement between brachial oscillometry, radial and carotid tonometry data and analysis of factors associated with their differences

Článek Clinical ethics consultation among Italian ethics committee: A mixed method study

Článek Epidemiology of tick-borne encephalitis in China, 2007- 2018

Článek Narrative warmth and quantitative competence: Message type affects impressions of a speaker

Článek Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains

Článek Comparison of quality control methods for automated diffusion tensor imaging analysis pipelines

Článek Self-efficacy, procrastination, and burnout in post-secondary faculty: An international longitudinal analysis

Článek Should social disconnectedness be included in primary-care screening for cardiometabolic disease? A systematic review of the relationship between everyday stress, social connectedness, and allostatic load

Článek Fast and accurate quantification of insertion-site specific transgene levels from raw seed samples using solid-state nanopore technology

Článek Maternal employment and child nutritional status in Uganda

Článek Correction: Saiga horn user characteristics, motivations, and purchasing behaviour in Singapore

Článek Disparities in survival by stage after surgery between pancreatic head and body/tail in patients with nonmetastatic pancreatic cancer

Článek Acknowledgements are not just thank you notes: A qualitative analysis of acknowledgements content in scientific articles and reviews published in 2015

Článek Interocular asymmetry of the superonasal retinal nerve fibre layer thickness and blood vessel diameter in healthy subjects

Článek Does it still fit? – Adapting affordance judgments to altered body properties in young and older adults

Článek Health-related quality of life in patients with atrial fibrillation: The role of symptoms, comorbidities, and the type of atrial fibrillation

Článek A systems approach identifies Enhancer of Zeste Homolog 2 (EZH2) as a protective factor in epilepsy

Článek Statistical learning and the uncertainty of melody and bass line in music

Článek The association between childhood maltreatment and empathic perspective taking is moderated by the 5-HTT linked polymorphic region: Another example of “differential susceptibility”

Článek Household air pollution and arthritis in low-and middle-income countries: Cross-sectional evidence from the World Health Organization’s study on Global Ageing and Adult Health

Článek Firefighters’ occupational stress and its correlations with cardiorespiratory fitness, arterial stiffness, heart rate variability, and sleep quality

Článek Diagnostic utility of CT for small bowel obstruction: Systematic review and meta-analysis

Článek Clinical nurses’ beliefs, knowledge, organizational readiness and level of implementation of evidence-based practice: The first step to creating an evidence-based practice culture

Článek Attitude and behaviour of Dutch Otorhinolaryngologists to Evidence Based Medicine

Článek Electronic cigarettes and insulin resistance in animals and humans: Results of a controlled animal study and the National Health and Nutrition Examination Survey (NHANES 2013-2016)

Článek Cytogenetics of the small-sized fish, Copeina guttata (Characiformes, Lebiasinidae): Novel insights into the karyotype differentiation of the family

Článek Infant rhesus macaque (Macaca mulatta) personality and subjective well-being

Článek Potential effects of ursodeoxycholic acid on accelerating cutaneous wound healing

Článek Healthcare utilization and costs of cardiopulmonary complications following cardiac surgery in the United States

Článek Prediction of train wheel diameter based on Gaussian process regression optimized using a fast simulated annealing algorithm

Článek Comparative de novo transcriptomics and untargeted metabolomic analyses elucidate complicated mechanisms regulating celery (Apium graveolens L.) responses to selenium stimuli

Článek Cognitive dysfunction in mice lacking proper glucocorticoid receptor dimerization

Článek Prevalence, awareness, treatment and control of hypertension and sodium intake in Zhejiang Province, China: A cross-sectional survey in 2017

Článek Autofluorescence spectroscopy in redox monitoring across cell confluencies

Článek Impact of mycoplasma pneumonia infection on urticaria: A nationwide, population-based retrospective cohort study in Taiwan

Článek Correction: Dual pathway for metabolic engineering of Escherichia coli to produce the highly valuable hydroxytyrosol

Článek Rapid label-free analysis of Opisthorchis viverrini eggs in fecal specimens using confocal Raman spectroscopy

Článek Associations of systemic, serum lipid and lipoprotein metabolic pathway gene variations with polypoidal choroidal vasculopathy in China

Článek MRI-guided, transrectal, intraprostatic steam application as potential focal therapeutic modality for prostatic diseases in a large animal translational model: A feasibility follow-up study

Článek Predicting breast cancer risk using personal health data and machine learning models

Článek External validation of the relative fat mass (RFM) index in adults from north-west Mexico using different reference methods

Článek A study on separation of the protein structural types in amino acid sequence feature spaces

Článek α-Lipoic acid prevents against cisplatin cytotoxicity via activation of the NRF2/HO-1 antioxidant pathway

Článek A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans

Článek The effect of prioritization over cognitive-motor interference in people with relapsing-remitting multiple sclerosis and healthy controls

Článek Ionomic and transcriptomic analyses of two cotton cultivars (Gossypium hirsutum L.) provide insights into the ion balance mechanism of cotton under salt stress

Článek Soluble lytic transglycosylase SLT of Francisella novicida is involved in intracellular growth and immune suppression

Článek Glucocorticoid and dietary effects on mucosal microbiota in canine inflammatory bowel disease

Článek Zoonotic Babesia: A scoping review of the global evidence

Článek Utility of citizen science data: A case study in land-based shark fishing

Článek Response of cassava cultivars to African cassava mosaic virus infection across a range of inoculum doses and plant ages

Článek Correction: Risk factors for tooth loss in adults: A population-based prospective cohort study

Článek Dynamic deformation of femur during medial compartment knee osteoarthritis

Článek A novel ε-sensitive correlation indistinguishable scheme for publishing location data

Článek Interaction between BDNF val66met polymorphism and personality on long-term cardiac outcomes in patients with acute coronary syndrome

Článek What factors do make quality improvement work in primary health care? Experiences of maternal health quality improvement teams in three Puskesmas in Indonesia

Článek Social anxiety changes the way we move—A social approach-avoidance task in a virtual reality CAVE system

Článek Evaluation of a savings-led family-based economic empowerment intervention for AIDS-affected adolescents in Uganda: A four-year follow-up on efficacy and cost-effectiveness

Článek From sea monsters to charismatic megafauna: Changes in perception and use of large marine animals

Článek Association between IQ and FMR1 protein (FMRP) across the spectrum of CGG repeat expansions

Článek Impact of sports activity on Polish adults: Self-reported health, social capital & attitudes

Článek Hold your breath – Differential behavioral and sensory acuity of mosquitoes to acetone and carbon dioxide

Článek Comparative analysis of eight DNA extraction methods for molecular research in mealybugs

Článek Age-dependent survival rate of the colonial Little Tern (Sternula albifrons)

Článek The metabotropic glutamate receptor subtype 1 regulates development and maintenance of lemniscal synaptic connectivity in the somatosensory thalamus

Článek Impact of HFE variants and sex in lung cancer

Článek Study of congenital Morgagnian cataracts in Holstein calves

Článek Decreasing prevalence of contamination with extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) in retail chicken meat in the Netherlands

Článek Screening of differentially expressed immune-related genes from spleen of broilers fed with probiotic Bacillus cereus PAS38 based on suppression subtractive hybridization

Článek Factors governing the performance of Auxiliary Nurse Midwives in India: A study in Pune district

Článek Writing in the air: Facilitative effects of finger writing in older adults

Článek Enzymatic production of bioactive peptides from scotta, an exhausted by-product of ricotta cheese processing

Článek Effect of endometriosis on the fecal bacteriota composition of mice during the acute phase of lesion formation

Článek Experimental infection of lambs with tick-borne encephalitis virus and co-infection with Anaplasma phagocytophilum

Článek Leishmania amazonensis resistance in murine macrophages: Analysis of possible mechanisms

Článek Comparison between the induced membrane technique and distraction osteogenesis in treating segmental bone defects: An experimental study in a rat model

Článek A dengue fever predicting model based on Baidu search index data and climate data in South China

Článek Revierparks as an integrated green network in Germany: An option for Amman?

Článek Detection and analysis of pulse waves during sleep via wrist-worn actigraphy

Článek From dangerous branches to urban banyan: Facilitating aerial root growth of Ficus rubiginosa

Článek Unilateral versus bilateral pedicle screw fixation in lumbar fusion: A systematic review of overlapping meta-analyses

Článek Edible ectomycorrhizal fungi and Cistaceae. A study on compatibility and fungal ecological strategies

Článek Physical space interacts with clonal fragmentation and nutrient availability to affect the growth of Salvinia natans

Článek Odd haemoglobins in odd-toed ungulates: Impact of selected haemoglobin characteristics of the white rhinoceros (Ceratotherium simum) on the monitoring of the arterial oxygen saturation of haemoglobin

Článek Somatic mutations in intracranial arteriovenous malformations

Článek Clinical feasibility of NGS liquid biopsy analysis in NSCLC patients

Článek Thrombospondin-I is a critical modulator in non-alcoholic steatohepatitis (NASH)

Článek Chemical analysis of Hg0-containing Hindu religious objects

Článek Hipk is required for JAK/STAT activity during development and tumorigenesis

Článek Transfer of skin microbiota between two dissimilar autologous microenvironments: A pilot study

Článek Correction: MiR-4524b-5p/WTX/β-catenin axis functions as a regulator of metastasis in cervical cancer

Článek Complete chloroplast genomes of two Siraitia Merrill species: Comparative analysis, positive selection and novel molecular marker development

Článek Lower levels of proteinuria are associated with elevated mortality in incident dialysis patients

Článek Optimising medication data collection in a large-scale clinical trial

Článek Personal response to immune checkpoint inhibitors of patients with advanced melanoma explained by a computational model of cellular immunity, tumor growth, and drug

Článek Hypofibrinolysis induced by tranexamic acid does not influence inflammation and mortality in a polymicrobial sepsis model

Článek Correction: Dose-dependent adverse effects of salinomycin on male reproductive organs and fertility in mice

Článek Endocrine profile of the VCD-induced perimenopausal model rat

Článek Inhibition of complement activation, myeloperoxidase, NET formation and oxidant activity by PIC1 peptide variants

Článek Domestication may affect the maternal mRNA profile in unfertilized eggs, potentially impacting the embryonic development of Eurasian perch (Perca fluviatilis)

Článek Intrauterine growth patterns in rural Ethiopia compared with WHO and INTERGROWTH-21st growth standards: A community-based longitudinal study

Článek Remote ischaemic conditioning and early changes in plasma creatinine as markers of one year kidney graft function—A follow-up of the CONTEXT study

Článek Validation of Plasmodium vivax centromere and promoter activities using Plasmodium yoelii

Článek Variation in neophobia among cliff swallows at different colonies

Článek Soil C, N, and P distribution as affected by plant communities in the Yellow River Delta, China

Článek Community-based sero-prevalence of hepatitis B and C infections in South Omo Zone, Southern Ethiopia

Článek Birth asphyxia and its associated factors among newborns in public hospital, northeast Amhara, Ethiopia

Článek Enhancement in dopamine reduces generous behaviour in women

Článek Correction: Risk factors for postoperative meningitis after microsurgery for vestibular schwannoma

Článek Correction: Evolution of high tooth replacement rates in theropod dinosaurs

Článek Hepatic sinusoidal hemophagocytosis with and without hemophagocytic lymphohistiocytosis

Článek Efficient intra mode decision for low complexity HEVC screen content compression

Článek Feature selection for helpfulness prediction of online product reviews: An empirical study

Článek Structure and age-dependent growth of the chicken liver together with liver fat quantification: A comparison between a dual-purpose and a broiler chicken line

Článek Important features of retail shoes for women with rheumatoid arthritis: A Delphi consensus survey

Článek The impact of gut microbiota manipulation with antibiotics on colon tumorigenesis in a murine model

Článek The characteristic of patulous eustachian tube patients diagnosed by the JOS diagnostic criteria

Článek Nine years of in situ soil warming and topography impact the temperature sensitivity and basal respiration rate of the forest floor in a Canadian boreal forest

Článek A novel model for malaria prediction based on ensemble algorithms

Článek “Because at school, you can become somebody” – The perceived health and economic returns on secondary schooling in rural Burkina Faso

Článek Experiences of health services and unmet care needs of people with late-stage Parkinson’s in England: A qualitative study

Článek Electrochemical analysis of uric acid excretion to the intestinal lumen: Effect of serum uric acid-lowering drugs and 5/6 nephrectomy on intestinal uric acid levels

Článek Does completion of sputum smear monitoring have an effect on treatment success and cure rate among adult tuberculosis patients in rural Eastern Uganda? A propensity score-matched analysis

Článek Identifying fetal yawns based on temporal dynamics of mouth openings: A preterm neonate model using support vector machines (SVMs)

Článek Hepatitis B virus seromarkers among HIV infected adults on ART: An unmet need for HBV screening in eastern Ethiopia

Článek Assessment of knowledge and practice of breast self-examination among reproductive age women in Akatsi South district of Volta region of Ghana

Článek Evaluation of quantitative biosensor for glucose-6-phosphate dehydrogenase activity detection

Článek Antibiotic treatment adequacy and death among patients with Pseudomonas aeruginosa airway infection

Článek Effects of experimentally induced fatigue on healthy older adults’ gait: A systematic review

Článek Monounsaturated fatty acids protect against palmitate-induced lipoapoptosis in human umbilical vein endothelial cells

Článek An assessment of the utility and repeatability of the renal resistive index in horses

Článek Analysis of center of mass acceleration and muscle activation in hemiplegic paralysis during quiet standing

Článek The association between dengue incidences and provincial-level weather variables in Thailand from 2001 to 2014

Článek Asylum seekers’ perspectives on vaccination and screening policies after their arrival in Greece and The Netherlands

Článek A new, fast method to search for morphological convergence with shape data

Článek Zinc thiazole enhances defense enzyme activities and increases pathogen resistance to Ralstonia solanacearum in peanut (Arachis hypogaea) under salt stress

Článek Effect of thermal control of dry fomites on regulating the survival of human pathogenic bacteria responsible for nosocomial infections

Článek Spatial dynamics in the classroom: Does seating choice matter?

Článek Hematologic profile of Amazon river dolphins Inia geoffrensis and its variation during acute capture stress

Článek Association between body mass index and asthma severity in Arab pediatric population: A retrospective study

Článek Toxic trajectories under future climate conditions

Článek Bioassay- and metabolomics-guided screening of bioactive soil actinomycetes from the ancient city of Ihnasia, Egypt

Článek Awareness of treatment: A source of bias in subjective grading of ocular complications

Článek Genome-wide identification and expression analysis of the PHD-finger gene family in Solanum tuberosum

Článek Exploring functional core bacteria in fermentation of a traditional Chinese food, Aspergillus-type douchi

Článek Folk theories of gender and anti-transgender attitudes: Gender differences and policy preferences

Článek Lower S-adenosylmethionine levels and DNA hypomethylation of placental growth factor (PlGF) in placental tissue of early-onset preeclampsia-complicated pregnancies

Článek Simulating the route of the Tang-Tibet Ancient Road for one branch of the Silk Road across the Qinghai-Tibet Plateau

Článek Evaluation of the ecological niche model approach in spatial conservation prioritization

Článek Important gene–gene interaction of TNF-α and VDR on osteoporosis in community-dwelling elders

Článek Traffic light labelling could prevent mortality from noncommunicable diseases in Canada: A scenario modelling study

Článek Choice-induced inter-trial inhibition is modulated by idiosyncratic choice-consistency

Článek HomeSTEAD’s physical activity and screen media practices and beliefs survey: Instrument development and integrated conceptual model

Článek What nature separated, and human joined together: About a spontaneous hybridization between two allopatric dogwood species (Cornus controversa and C. alternifolia)

Článek Cell sources of inflammatory mediators present in bone marrow areas inside the meniscus

Článek The effects of exercise variation in muscle thickness, maximal strength and motivation in resistance trained men

Článek High prevalence of abnormal menstruation among women living with HIV in Canada

Článek A quantitative engineering study of ecosystem robustness using thermodynamic power cycles as case studies

Článek External morphology and developmental changes of tarsal tips and mouthparts of the invasive spotted lanternfly, Lycorma delicatula (Hemiptera: Fulgoridae)

Článek Small joint arthrodesis technique using a dowel bone graft in a rabbit model

Článek An investigation of far and near transfer in a gamified visual learning paradigm

Článek Isolation and characterization of fowl aviadenovirus serotype 11 from chickens with inclusion body hepatitis in Morocco

Článek Translocation of Mycobacterium tuberculosis after experimental ingestion

Článek Health literacy as a mediator of the relationship between socioeconomic status and health: A cross-sectional study in a population-based sample in Florence

Článek Genomic insights on heterogeneous resistance to vancomycin and teicoplanin in Methicillin-resistant Staphylococcus aureus: A first report from South India

Článek “I am alive; my baby is alive”: Understanding reasons for satisfaction and dissatisfaction with maternal health care services in the context of user fee removal policy in Nigeria

Článek A systems biology approach uncovers a gene co-expression network associated with cell wall degradability in maize

Článek Correction: DNA barcodes corroborating identification of mosquito species and multiplex real-time PCR differentiating Culex pipiens complex and Culex torrentium in Iran

Článek Heterogeneous root zone salinity mitigates salt injury to Sorghum bicolor (L.) Moench in a split-root system

Článek Effects and cost-effectiveness of postoperative oral analgesics for additional postoperative pain relief in children and adolescents undergoing dental treatment: Health technology assessment including a systematic review

Článek Spatial ecology of coyotes in the urbanizing landscape of the Cuyahoga Valley, Ohio

Článek The role of gadolinium in magnetic resonance imaging for early prostate cancer diagnosis: A diagnostic accuracy study

Článek Modeling succinate dehydrogenase loss disorders in C. elegans through effects on hypoxia-inducible factor

Článek The association of parents’ behaviors related to salt with 24 h urinary sodium excretion of their children: A Spanish cross-sectional study

Článek Transcriptional changes during hepatic ischemia-reperfusion in the rat

Článek NAT2 gene polymorphisms and endometriosis risk: A PRISMA-compliant meta-analysis

Článek Effects of lutein supplementation in age-related macular degeneration

Článek Correction: Genetic susceptibility to angiotensin-converting enzyme-inhibitor induced angioedema: A systematic review and evaluation of methodological approaches

Článek Recovery cycles of posterior root-muscle reflexes evoked by transcutaneous spinal cord stimulation and of the H reflex in individuals with intact and injured spinal cord

Článek Virulence beneath the fleece; a tale of foot-and-mouth disease virus pathogenesis in sheep

Článek The delay of motherhood: Reasons, determinants, time used to achieve pregnancy, and maternal anxiety level

Článek Glycated albumin as a diagnostic tool in diabetes: An alternative or an additional test?

Článek Quantification of circulating cell-free DNA (cfDNA) in urine using a newborn piglet model of asphyxia

Článek Correction: Elevated levels of eEF1A2 protein expression in triple negative breast cancer relate with poor prognosis

Článek Inhibiting the copper efflux system in microbes as a novel approach for developing antibiotics

Článek Rapid pathogen identification and antimicrobial susceptibility testing in in vitro endophthalmitis with matrix assisted laser desorption-ionization Time-of-Flight Mass Spectrometry and VITEK 2 without prior culture

Článek Identification of loci of functional relevance to Barrett’s esophagus and esophageal adenocarcinoma: Cross-referencing of expression quantitative trait loci data from disease-relevant tissues with genetic association data

Článek Inter- and intraspecific diversity of food legumes among households and communities in Ethiopia

Článek Walking-speed estimation using a single inertial measurement unit for the older adults

Článek The relationship between glutathione levels in leukocytes and ocular clinical parameters in glaucoma

Článek The home field advantage of modern plant breeding

Článek High concentrations of middle ear antimicrobial peptides and proteins and proinflammatory cytokines are associated with detection of middle ear pathogens in children with recurrent acute otitis media

Článek A modern approach to identifying and characterizing child asthma and wheeze phenotypes based on clinical data

Článek Validation of a novel time-to-event nest density estimator on passerines: An example using Brewer’s sparrows (Spizella breweri)

Článek Use of GeneXpert and the role of an expert panel in improving clinical diagnosis of smear-negative tuberculosis cases

Článek Heat-induced hyperthermia impacts the follicular fluid proteome of the periovulatory follicle in lactating dairy cows

Článek One-shot phase-recovery using a cellphone RGB camera on a Jamin-Lebedeff microscope

Článek Change of surfactant protein D and A after renal ischemia reperfusion injury

Článek Antibiotic saving effect of combination therapy through synergistic interactions between well-characterized chito-oligosaccharides and commercial antifungals against medically relevant yeasts

Článek Impact of the change in the antitubercular regimen from three to four drugs on cure and frequency of adverse reactions in tuberculosis patients from Brazil: A retrospective cohort study

Článek Ontogenic mRNA expression of RNA modification writers, erasers, and readers in mouse liver

Článek Intrinsic and extrinsic factors associated with sputum characteristics of presumed tuberculosis patients

Článek Vaccination with a live-attenuated small-colony variant improves the humoral and cell-mediated responses against Staphylococcus aureus

Článek A versatile modular vector set for optimizing protein expression among bacterial, yeast, insect and mammalian hosts

Článek Rapid evolution of prey maintains predator diversity

Článek Correction: Consumption of rice, acceptability and sensory qualities of fortified rice amongst consumers of social safety net rice in Nepal

Článek Indicators to distinguish symptom accentuators from symptom producers in individuals with a diagnosed adjustment disorder: A pilot study on inconsistency subtypes using SIMS and MMPI-2-RF

Článek Postural stability of 5-year-old girls and boys with different body heights

Článek The association between exposure to interferon-beta during pregnancy and birth measurements in offspring of women with multiple sclerosis

Článek Variations in neurotoxicity and proteome profile of Malayan krait (Bungarus candidus) venoms

Článek Altered functional connectivity density in the brains of hemodialysis end-stage renal disease patients: An in vivo resting-state functional MRI study

Článek Transboundary movements of foot-and-mouth disease from India to Sri Lanka: A common pattern is shared by serotypes O and C

Článek Medical and productivity costs after trauma

Článek Defining pharmacists' roles in disasters: A Delphi study

Článek Comprehensive assessment of tissue and serum parameters of bone metabolism in a series of orthopaedic patients

Článek Predictors of alcohol use transitions among drug-using youth presenting to an urban emergency department

Článek Longitudinal changes in structural lung abnormalities using MDCT in chronic obstructive pulmonary disease with asthma-like features

Článek Endocannabinoid 2-arachidonoylglycerol is elevated in the coronary circulation during acute coronary syndrome

Článek Contextual factors and sporting success: The relationship between birth date and place of early development on the progression of Jamaican track and field athletes from junior to senior level

Článek Potential application of Aloe Vera-derived plant-based cell in powering wireless device for remote sensor activation

Článek Retraction: Inhibition of reactive gliosis prevents neovascular growth in the mouse model of oxygen-induced retinopathy

Článek Measuring and addressing the childhood tuberculosis reporting gaps in Pakistan: The first ever national inventory study among children

Článek Arterial blood gas analysis in dogs with bronchomalacia

Článek Trends in the incidence of thymoma, thymic carcinoma, and thymic neuroendocrine tumor in the United States

Článek Optogenetic inhibition of ventral hippocampal neurons alleviates associative motor learning dysfunction in a rodent model of schizophrenia

Článek Safe and effective subcutaneous adipolysis in minipigs by a collagenase derivative

Článek The correlation between optical coherence tomography retinal shape irregularity and axial length

Článek Length of gestation and birth weight are associated with indices of combined kidney biomarkers in early childhood

Článek Essential oil-incorporated carbon nanotubes filters for bacterial removal and inactivation

Článek Domiciliary high-flow treatment in patients with COPD and chronic hypoxic failure: In whom can we reduce exacerbations and hospitalizations?

Článek Comprehensive analysis of putative dihydroflavonol 4-reductase gene family in tea plant

Článek Comparative proteomic analysis of mitochondria isolated from Euglena gracilis under aerobic and hypoxic conditions

Článek Secreted metabolite-mediated interactions between rhizosphere bacteria and Trichoderma biocontrol agents

Článek Experimental evidence of subtle victim blame in the absence of explicit blame

Článek Effects of different fatigue locations on upper body kinematics and inter-joint coordination in a repetitive pointing task

Článek Cannula and circuit management in peripheral extracorporeal membrane oxygenation: An international survey of 45 countries

Článek Economic evaluations of screening strategies for the early detection of colorectal cancer in the average-risk population: A systematic literature review

Článek Vitreous levels of Lipocalin-2 on patients with primary rhegmatogenous retinal detachment

Článek Light intensity and spectrum affect metabolism of glutathione and amino acids at transcriptional level

Článek The potential role of acrolein in plant ferroptosis-like cell death

Článek General practitioners’ consultation counts and associated factors in Swiss primary care – A retrospective observational study

Článek Potential of mesenchymal- and cardiac progenitor cells for therapeutic targeting of B-cells and antibody responses in end-stage heart failure

Článek Correction: Constitutive expression of an A-5 subgroup member in the DREB transcription factor subfamily from Ammopiptanthus mongolicus enhanced abiotic stress tolerance and anthocyanin accumulation in transgenic Arabidopsis

Článek A single institution experience of the treatment of pancreatic ductal carcinoma: The demand and the role of radiation therapy

Článek Correction: Intestinal mucosal injury induced by obstructive jaundice is associated with activation of TLR4/TRAF6/NF-κB pathways

Článek Relationship between scapular initial position and scapular movement during dynamic motions

Článek Correction: The circadian rhythm of bladder clock genes in the spontaneously hypersensitive rat

Článek Applications of machine learning in decision analysis for dose management for dofetilide

Článek Retraction: Nuclear factor kappa-B signaling is integral to ocular neovascularization in ischemia-independent microenvironment

Článek Using archaeological and geomorphological evidence for the establishment of a relative chronology and evolution pattern for Holocene landslides

Článek Who reported having a high-strain job, low-strain job, active job and passive job? The WIRUS Screening study

Článek Longitudinal monitoring of KRAS-mutated circulating tumor DNA enables the prediction of prognosis and therapeutic responses in patients with pancreatic cancer

Článek Retraction: Epigenetic Silencing of Peroxisome Proliferator-Activated Receptor γ Is a Biomarker for Colorectal Cancer Progression and Adverse Patients’ Outcome

Článek Correction: Severe cases of seasonal influenza in Russia in 2017-2018

Článek Differences between occupational and non-occupational-related motor vehicle collisions in West Virginia: A cross-sectional and spatial analysis

Článek Expression of concern: Zinc transporter 8 (ZnT8) expression is reduced by ischemic insults: A potential therapeutic target to prevent ischemic retinopathy

Článek Correction: Cattle intestinal microbiota shifts following Escherichia coli O157:H7 vaccination and colonization

Článek Correction: Development of UV spectrophotometry methods for concurrent quantification of amlodipine and celecoxib by manipulation of ratio spectra in pure and pharmaceutical formulation

Článek Correction: Modelling of the breadth of expression from promoter architectures identifies pro-housekeeping transcription factors

Článek Correction: Development of rice conidiation media for Ustilaginoidea virens

Článek Retraction: The Nexus between VEGF and NFκB Orchestrates a Hypoxia-Independent Neovasculogenesis

Článek Correction: Foraging strategies are maintained despite workforce reduction: A multidisciplinary survey on the pollen collected by a social pollinator

Článek Retraction: MicroRNA-493 Suppresses Tumor Growth, Invasion and Metastasis of Lung cancer by Regulating E2F1

Článek Correction: On the trail of Scandinavia’s early metallurgy: Provenance, transfer and mixing

Článek Correction: Novel insights into the morphology of Plesiochelys bigleri from the early Kimmeridgian of Northwestern Switzerland

Článek Correction: Supplementation of diet with non-digestible oligosaccharides alters the intestinal microbiota, but not arthritis development, in IL-1 receptor antagonist deficient mice

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2019 Číslo 12

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Získaná hemofilie - Povědomí o nemoci a její diagnostika

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Eozinofilní granulomatóza s polyangiitidou

Autori: doc. MUDr. Martina Doubková, Ph.D.

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