Learning efficient haptic shape exploration with a rigid tactile sensor array
Authors:
Sascha Fleer aff001; Alexandra Moringen aff001; Roberta L. Klatzky aff002; Helge Ritter aff001
Authors place of work:
Neuroinformatics Group, Bielefeld University, Bielefeld, Germany
aff001; Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
aff002
Published in the journal:
PLoS ONE 15(1)
Category:
Research Article
doi:
https://doi.org/10.1371/journal.pone.0226880
Summary
Haptic exploration is a key skill for both robots and humans to discriminate and handle unknown objects or to recognize familiar objects. Its active nature is evident in humans who from early on reliably acquire sophisticated sensory-motor capabilities for active exploratory touch and directed manual exploration that associates surfaces and object properties with their spatial locations. This is in stark contrast to robotics. In this field, the relative lack of good real-world interaction models—along with very restricted sensors and a scarcity of suitable training data to leverage machine learning methods—has so far rendered haptic exploration a largely underdeveloped skill. In robot vision however, deep learning approaches and an abundance of available training data have triggered huge advances. In the present work, we connect recent advances in recurrent models of visual attention with previous insights about the organisation of human haptic search behavior, exploratory procedures and haptic glances for a novel architecture that learns a generative model of haptic exploration in a simulated three-dimensional environment. This environment contains a set of rigid static objects representing a selection of one-dimensional local shape features embedded in a 3D space: an edge, a flat and a convex surface. The proposed algorithm simultaneously optimizes main perception-action loop components: feature extraction, integration of features over time, and the control strategy, while continuously acquiring data online. Inspired by the Recurrent Attention Model, we formalize the target task of haptic object identification in a reinforcement learning framework and reward the learner in the case of success only. We perform a multi-module neural network training, including a feature extractor and a recurrent neural network module aiding pose control for storing and combining sequential sensory data. The resulting haptic meta-controller for the rigid 16 × 16 tactile sensor array moving in a physics-driven simulation environment, called the Haptic Attention Model, performs a sequence of haptic glances, and outputs corresponding force measurements. The resulting method has been successfully tested with four different objects. It achieved results close to 100% while performing object contour exploration that has been optimized for its own sensor morphology.
Keywords:
Learning – Employment – Machine learning algorithms – machine learning – Recurrent neural networks – Touch – Robots – Tactile sensation
Introduction
While the sense of touch is central to human life, tactile capabilities of robots are currently hardly developed. This stark contrast becomes even more apparent if one compares touch and vision: while good camera sensors have become affordable and ubiquitous items and huge image and video databases together with deep learning have brought computer vision close (some would argue on par) to human vision [1–3], comparable advances in robot touch are widely lacking [4–7].
One reason is the very limited maturity of tactile sensors as compared with human skin. A second and deeper reason is that touch differs from vision in an important way: while looking at an object leaves its state unaffected, touch requires physical contact, coupling the sensor and the object in potentially complex and rich ways that usually also change the position, orientation or even the shape of the object. Human haptics makes active and sophisticated use of this richness to lend us skills such as haptic exploration, discrimination, manipulation and more. Large parts of these tasks are hard or impossible to model sufficiently accurately to replicate them on robots, thereby calling again for machine learning approaches similar to those that were highly successful in vision. However, the highly interactive nature of touch makes not only the learning problem itself much more difficult but also creates a problem for the availability of meaningful training data, since information about interactive haptics is much harder to capture in databases of static tactile patterns. As a consequence, learning approaches for the modality of interactive touch are still largely in their infancy and tactile skills enabling robots to establish and control rich and safe contact with objects or even humans are still a largely unsolved challenge which severely limits the use of robots in both domestic and industrial applications.
In this work we focus on using machine learning for the synthesis of one central and important haptic skill: the discrimination of unknown object shapes through a sequence of actively controlled haptic contacts between a sensor and the object surface. Our approach builds on recent advances that show how a deep network can be made to learn to integrate a sequence of visual observations to discriminate visual patterns. We extend this approach from the visual to the haptic domain and—by taking inspiration from insights about the organization of haptical exploration in humans—we create a potentially interesting new bridge between a computational understanding of interactive touch in robotics and in human haptics.
In humans, haptic capabilities are available at birth, for example, those that are necessary for a neonate to nurse. Over the course of early development, increasingly sophisticated haptic exploration comes on-line, as children acquire motor control and the ability to focus attention. By pre-school age, children demonstrate adult-like patterns of exploration [8] that they gate according to contextual demands [9]. This developmental process results in a small set of optimized action patterns, widely known under the term exploratory procedures (EPs) [10]. Humans use EPs to extract properties such as texture, hardness, weight, volume, or local shape features.
Under some circumstances, the level of complexity in haptic exploration can be effectively reduced to what was termed the haptic glance by Klatzky and Ledermann [11]. Specifically, they define the haptic glance as brief, spatially constrained contact that involves little or no movement of the fingers. In the same work they pose the question how the information from a haptic glance is translated into effective manipulation. Following this work, we are interested in a connection/transition between a haptic glance and an exploratory procedure. We propose that a haptic glance constitutes an atomic, primitive exploratory entity. We furthermore assume that an EP can be represented by a sequence of such primitives, if parameterization of each individual haptic glance is chosen in an optimal way. On a long-term scale, we are targeting the question: How can one model optimal control of haptic glances for optimal task-specific haptic exploration of an unknown object or scene? Will the resulting sequence of haptic glances emerge as a full EP? In order to answer this question affirmatively, such a control model should ideally contain a strategy to efficiently extract task-specific cues based on previously available information (if any), and integrate these over time. For computational purposes we make the following assumptions. Firstly, we assume that a haptic glance—being the simplest haptically directed action—is a foundation for any more complex haptic behavior, including haptic exploratory procedures of any type. Therefore, it is our goal to learn an optimal sequence of haptic glances, adapted to a given task and a sensor morphology that is provided beforehand and is specific for a given robot platform. Secondly, we assume that a haptic glance is defined by a tuple consisting of a pressure profile yielded by the tactile sensor at contact and the corresponding sensor pose.
Robots, like humans, benefit from haptic sensors in order to find, identify, and manipulate objects. Tactile sensing applications in robotics are built out of two different categories [12]. The first one is called “perception for action”, which utilizes the tactile information to solve dexterous manipulation tasks including grasping, slip prevention. The second category, which has recently become a popular area of research, is named “action for perception”, dealing with recognition and exploration [13–15]. Recent developments have added machine learning techniques in order to learn exploration strategies, feature extraction or a better estimation of different quantities. One class of methods is reinforcement learning, a biologically inspired class of learning methods in which the agent learns by gathering data through the active exploring of the environment [16]. It is applied to teach a robot dexterous manipulation [17, 18] or to use learned exploration strategies in the form of tactile skills in order to facilitate exploration as studied for surface classification [15].
The approach employed in this work provides one possible solution to a typically puzzling question: how to couple optimization of both above-mentioned directions, “perception for action”, and “action for perception”. In computer vision, the analogous question has already been investigated by measures of recurrent models of visual attention (RAM) [19, 20]. RAM acquires image glimpses by controlling the movement of a simulated eye within the image. The modeling approach is inspired by the fact that humans are not perceiving their environment as a whole image. Instead, they see only parts of the scene, while the location of the fixations depends on the current task [21, 22]. The model gathers information about the environment directed by image-based and task-dependent saliency cues [23, 24]. Information extracted from these foveal “glimpses” is then combined in order to get an accumulated understanding of the visible scene. RAM applied to control of the sequences of haptic glances optimizes both above-mentioned directions simultaneously in a series of iterative steps, and enables us to find an optimal solution for a given tactile end-effector, with respect to its own constraints and the spatio-temporal resolution of the acquired data.
Inspired by this work, we present a framework that is able to identify four different objects using a tactile sensor array within a simulated environment. The object classification and pose control are formalized as a sequential decision-making process within a reinforcement learning framework, where an artificial agent is able to perform multiple haptic glances before the final estimation of the object’s class. During the training of a multi-component deep neural network, we learn how to control the pose of the rigid tactile sensor in a way that is beneficial for the classification task. To enable integration of information gained through multiple haptic glances, we employ a recurrent neural network as one building block of this architecture. The next section describes the simulation setup and the employed algorithm, together with the training procedure. After presenting the conducted experiments, we summarize and discuss the obtained results.
Scenario and experimental setup
To develop an efficient haptic controller that can enable a robot to identify objects with a sequence of haptic glances, we perform a comprehensive experimental investigation in Gazebo (see S1 Code), a physics-driven simulation environment. The simulation consists of two main parts as illustrated in Fig 1.
The tactile sensor array—Myrmex
The first part is a floating standalone tactile sensor array, modeled to resemble the Myrmex [25] sensor in order to ease the transfer to a real robot in future experiments. It is constructed out of a circular end-effector mount (red) with a square sensitive zone (black). In simulation, one side of the sensor contains a square-shaped array of 16 × 16 cells covering a surface of 64 cm2, whose values are computed to approximately resemble the values of the real sensor array (see S2 Code). Contacts at collision are estimated by Gazebo’s physics engine ODE according to inter-penetration of objects (intrinsic compliance) and to default local surface parameters. An example of the contact information available in Gazebo and its characteristics are shown in S1 Video.
Each contact defined by its position and force vector, generates a Gaussian distribution around the contact center with amplitude depending only on the normal force. The standard deviation is arbitrarily fixed to mimic the deformation of the sensitive foam on the real sensor. Mixing the distributions creates a 16 × 16 tactile pressure image, that is represented as an array of floating point values contrary to the real sensor with only 4096 levels of pressure. When measuring the collision with an edge as it is illustrated in Fig 1, we expect to see a line. However, due to the limitations of the collision library, we acquire the image presented in the bottom left corner. In Fig 2 the tactile image for a contact with a cuboid is shown for both the simulated Myrmex sensor (Fig 2(a)), and the real sensor (Fig 2(b)). The collision library libccd used by the ODE simulation engine of Gazebo can generate only two contact points at a time (see S1 Video). Consequently, it is not possible to produce an edge in the resulting tactile image. On the contrary, the real sensor produces a tactile image in which the expected line of contact is visible.
Communication with the simulated sensor in Gazebo is performed via a ROS-interface (see S3 Code).
Stimulus material
The second part is the stimulus material. It exists as a static set of 3D objects that are distributed in the simulation environment, but also in the form of real 3D wooden building blocks with 3D elementary shapes carved on top. Our current set of elementary shape types consists of approximately 60 prototypes. A combination of such building blocks forms the so-called Modular Haptic Stimulus Board (MHSB) (see S2 Video for design and applications and S1 Project for the MHSB project web-site). By rearranging the blocks, MHSBs of different sizes and different shape configurations have been previously employed in a range of studies of haptic exploration and search in humans (e.g., [26–28]). Through its modularity, MHSB enables a flexible experimental design resulting in a wide range of 3D shape landscapes.
All shapes within the current setup are rigid, stationary and have the same height. Building blocks employed for this experiment, 9 × 9 cm each, were chosen, firstly, to suit the size of the real Myrmex sensor and the restrictions of its control with the real KUKA robot arm. For this work, we have chosen a set of objects locally representing basic types of one-dimensional curvature features, e.g. edge, flat descendent/horizontal surface, and a convex surface. Due to the fact that concave surfaces may be more challenging for the simulated sensor, we are omitting them in the current work. This one-dimensional curvature design enabled us to constrain parameterization of haptic glances to two dimensions, translation and rotation along one axis, together with the linear arrangement of the shapes, without loss of generality. In case new features are considered within the experimental stimulus design, new types of control parameters as well as new output have to be used for an implementation of the haptic glance controller. For example, in case objects are equal w.r.t. the curvature and can be differentiated based on height only (a set of cuboids of different heights), a haptic glance controller needs to output the height of collision with the object as well as the pressure profile.
Haptic control of the simulated Myrmex
Haptic control consists of two parts, a low-level controller that performs haptic glances and a higher-level controller that provides parameterization for the low-level controller and is responsible for solving the task.
The high-level meta-controller—HAM
The process of haptic exploration is operated by the so-called meta-controller: the Haptic Attention Model (HAM). It is represented by a deep neural network and is described in detail in the Methods Section. Its main task is to classify the given object, while constantly providing a new expedient target pose ξ = (xg, yg, zg, e1, e2, e3) of the sensor, including three position coordinates (xg, yg, zg) and three orientations (e1, e2, e3), to the low-level controller for further exploration. It performs the optimization for the parameterization of haptic glances based on the state of the networks’ working memory, a representation of the previously acquired haptic data. For proof of concept, we restricted the number of parameters that have to be provided by the HAM to the position along the x-axis and the angle around the y-axis. Before the execution of the haptic glance, the sensor is positioned at a specific pose where xg and the Euler angle e2 are specified by the output of the network l → = ( x g , e 2 ) ⊤. For the sake of readability, the alterable position xg is called x and the angle e2 is called φ in the following sections.
The low-level haptic glance controller
Without loss of generality, we use a simplified and naive representation of the low-level controller as illustrated in Fig 3. It executes a primitive haptic interaction specified by two parameters which are provided by the HAM. Given a pose, it outputs the acquired pressure, g : ( x , φ ) → p →. An execution of the glance controller moves Myrmex from a predefined (x, y, z)-position down along the z-axis. To this end, it gradually decreases its height—indicated by the value z—while keeping both the orientation and the (x, y) position constant until a collision with an object takes place (see S3 Video). Upon collision with the object, handled by the physics engine with minimal penetration when the overall pressure level on the sensor reaches a certain threshold, the motion stops and the sensor outputs its readings. To compute it, the forces applied to the 16 × 16 sensor cells of the Myrmex sensor are summed up. The threshold value is reached, when an overall force of 2 N is distributed over the contact surface of the Myrmex, i.e. 2 N/64 cm2 = 312.5 Pa. The main feature of this controller, implemented with the “hand of god” plugin (see S4 Code), is the constant sustainment of the sensor’s orientation and the (x, y) position up to the time of collision. This is realized by switching off the gravity and continuously holding the sensor pose at a predefined value against the impact of any impulses. By this means, the full control of both the pose parameters and the resulting tactile measurement is guaranteed. Additionally, this restricted implementation resembles the movement of the sensor when attached to a robot arm.
In this work, determined by the type of tactile sensing available as well as the restricted design of the haptic object properties, the haptic glance controller employed by the network is parameterized only by the pose. However, the parameterization may be extended, or, alternatively, a set of differently parameterized haptic glance controllers, similar to a functional basis, may be employed by the network. An example of an extension would be a function g ^ : ( x , φ ) → ( p → , h ) that maps from the pose to the tuple containing both the pressure and the corresponding height. Such parameterization is necessary in case the stimuli differ in height. If we further extend the shape complexity from the one-dimensional to a two-dimensional curvature feature, two orientation parameters instead of one will account for the data acquisition, i.e. g ^ : ( x , φ x , φ y ) → ( p → , h ).
Classification task
During training and classification, the agent is always presented with one out of four objects. It explores the restricted object space with the sensor by performing a predefined number of haptic glances. In order to learn an exploration policy that is independent of the object’s pose within the global coordinate system, we introduce exploration zones illustrated with dashed lines in Fig 1. Exploration zones are pre-defined regions with their own local coordinate systems, in which the objects are placed for exploration. After specification of the exploration zone, two out of six pose parameters of the tactile sensor can be modified by the high-level meta-controller as explained in the previous section. To preclude learning the absolute position of the object, its coordinates within the simulation space are mapped to an exploration zone x ∈ [−1, 1], corresponding to the range in which the output of the neural network lies. Due to the location of the pressure-sensitive surface on only one side of the Myrmex, rotations are performed within the range φ ∈ [−π/2, + π/2]. Further rotation will not yield contact information between the object and the sensor surface. The acquired pressure information is employed not only to classify the given object but also to determine the next position and orientation of the sensor in the next exploration step.
Methods
Reinforcement learning is a well-known class of machine learning algorithms for solving sequential decision-making problems through maximization of a cumulative scalar-valued reward function [16]. To formalize our task as a reinforcement learning problem, the artificial agent receives a reward of r = 1 for a correctly classified object and a reward of r = 0 otherwise. We then use the standard formulation of a Markov decision process defined by the tuple (S, A, PA, R, γ, S0), where S denotes the set of states and A the set of admissible actions. PA is the set of transition matrices, one for each action a ∈ A with matrix elements P s → , s → s ′ a specifying the probability to end up in state s → ′ after taking action a from state s →. Finally, r ∈ R ⊂ R is a scalar valued reward the agent receives after ending up in s → s ′, γ the discount factor and S0 ⊆ S is the set of starting states. The goal is to find an optimal policy π: S → A that maximizes the discounted future reward
The discount factor γ ∈ [0, 1) balances the weighting between present rewards and rewards that lie increasingly in the future.
A neural network with a set of weights θ can be employed to solve a reinforcement learning task, i.e., its output should maximize a given reward function Rt. In this case we can perform a gradient-based policy optimization with the help of the REINFORCE update rule [29, 30]. The general rule for updating the corresponding weights θ of the network is thus given by
The details of the application of these equations to our work is described in the section below.
The haptic attention model
In the following, the architecture of our designed high-level meta-controller, called the haptic attention model is described in detail. An overview of the interaction loop between the network and the simulation is displayed in Fig 4. Inspired by the architectures in [19, 20], the meta-controller network is constructed from three modules which are described in detail in the following subsections (See also S5 Code). A vector s → = ( x , φ , p → ) ⊤ consisting of the sensor pose (x, φ) and the corresponding pressure profile acquired by Myrmex performing a haptic glance in Gazebo is used as the sensory input for the network. The 16 × 16 pressure matrix is flattened to a normalized pressure vector p → with dim ( p → ) = 256. For the normalization we employ the L2-norm. Apart from the considerations of numerical stability during network training (no small/large numbers and no large differences), the normalization is performed in order to get rid of artifacts in the data caused by the method chosen to perform a haptic glance in simulation. These artifacts are specific to moving the floating Myrmex towards an object at an unknown position in tiny discrete steps, which is likely to produce a different strength of signal depending on the distance between the sensor and the object in the last step prior to collision. Therefore, normalization is performed in order to achieve a comparable pressure profile for a given pose, independent of the force, whose absolute strength in this particular case is a simulation artifact.
First, the input is processed through the tactile network, which combines the recorded pressure profile p → with its corresponding location x and orientation φ into one single feature vector. The features s → are then propagated through a long short-term memory (LSTM) network [31]. This kind of neural network belongs to the class of “recurrent neural networks” which have the ability to store, combine and process sequential data. It is constructed using hidden states of 256 neurons. The LSTM provides features to the object classifier and to the location network that in turn provides a new pose. Although the classification of the object can be done within each glance, we usually refer to the classification result after the final glance.
If not stated otherwise, all layers are connected through rectified linear units (ReLu) [32] as activation functions. The linear layers of the whole model are all built out of 64 neurons. For more information about (recurrent) neural networks see e.g., [33].
The tactile network
The tactile network is displayed in detail in Fig 5. It combines the tactile response of the sensor p → with the corresponding location x and angle φ. An important choice is the approach used to combine what (i.e., the pressure p) with where (i.e., position x and orientation φ). While [19] use an element-wise addition of the two features, [20, 34] suggest using element-wise multiplication. In this work, based on the performed tests, we concatenate the two resulting types of features followed by two additional linear layers. In this way, we do not impose a specific inner structure on the combination process, but let the network resolve this issue on its own.
The location network
The location network is designed to output the pose of the next haptic glance. The feature vector that is used as the input to this module is the output that is generated by the LSTM unit. It thus implicitly integrates shape information yielded by the previously performed glances. A stochastic location policy is modeled using two Gaussian distributions for position and orientation, respectively with variable mean μ and standard deviation σ as shown in Fig 6.
The features of the LSTM are propagated through a linear layer that outputs the mean μ(θ)∈[−1, 1] and the standard deviation σ(θ) of the Gaussian θ is referring to the corresponding weights of the model that are necessary to generate the desired output, which is in this case μ or σ. The extent of exploration of the location policy is given by the size of the Gaussian’s standard deviation σ. While for large σ, the raw location of the glance, given by μ, is imprecise, the location has more precision for smaller σ.
The two above-mentioned pipelines are used for computing a distinct μ and σ for the position and for orientation. The used activation function for the output layers are chosen to limit the resulting values to a reasonable range. While the tanh is used as the activation function to generate the mean within the desired range, the softplus function [35] is implemented as the activation function for the standard deviation. The output values μ(θ) and σ(θ) are then used to compute the new location and orientation by sampling from the respective 1-dimensional Gaussians for each of the desired variables.
To ensure that the location and position of the sensor remain within the predefined space around the to-be-classified object and also that the orientation remains within its boundaries, the sampled values of the Gaussians N ( q ; μ , σ ) are again restricted to the range q ∈ [−1, 1]. Thus, if q is sampled outside this range, it is resampled. The new pose vector is then given as
The classification network
In order to classify a given object, the generated feature vector of the LSTM is not only transferred to the location network, but also propagated through a different linear layer that is then used for classification. To achieve this, the softmax-function is utilized to encode the predicted class-affiliation of the current object o in a probability density π ( o | τ → 1 : s ; θ t ), representing the current policy of the reinforcement learning agent. Here, τ → 1 : S ( θ t ) encodes the accumulated LSTM feature vector after S glances, using the current set of weights θt at training step t. For classification, the class o with the highest probability
Training
For each training step, a new batch of size 64 is generated, where the to-be-classified objects o are uniformly chosen from the set of all four available objects. The target loss function L, used for training, is composed of two different components: classification and location. The update rule for both parts is derived from the REINFORCE algorithm. For the classification component of the loss, we see the designed model as a reinforcement learner which has to choose the right action in order to classify the given object. For classifying the object correctly it receives a reward r = 1, and r = 0 otherwise. The predicted probability of correctly identifying the target object o after S glances is then given as π ( o | τ → 1 : S ; θ ). To this end, the categorical cross-entropy can be used to compute the loss.
For learning the means μx and μφ of the location component of the policy, the characteristic eligibility as outlined in Eq (3) is used. σx and σφ are learned by applying Eq (4). The hybrid update rule is then given by
The function π(o) gives the computed classification probability that the to-be-classified object is object o, while yo is 1 if o corresponds to the correct object and 0 otherwise.
The parameter β controls the contribution of the different parts of the update. While for β = 1 both parts of the update contribute equally to the weight update, a smaller factor of β < 1 assigns more resources to the classification part. For β = 0, the part of the update that involves the location network is completely omitted [34].
The baseline layer is updated separately, using the mean-squared error. Instead of training the baseline only on the accumulated tactile information of the last glance τ → 1 : S, the training can be improved by also using all included sub-sequences τ → 1 : s with s ≤ S [34]. This leads to the loss function
The overall network model is trained using stochastic gradient descent with Nesterov momentum [36, 37]. The chosen learning rate of α0 decays towards αmin every training-step t with a decay factor of δα and a step-size of T according to
Due to the design of the network that generates a location for the next haptic glance, no fixed training set can be used to train the classifier. The current batch specifies only the to-be-classified objects, while the first pressure-location pair is chosen by the first random glance for each object. The location for any further glance is chosen by the current state of the location policy of the network.
Experiments
To perform an empirical examination of the validity of the network architecture, we perform a series of evaluations with a focus on each one of the three modules: the LSTM, the location network, and the tactile network. The core of the evaluation approach focuses on the recurrent LSTM unit that plays a central role in feature extraction and integration. Our hypothesis is that by employing LSTM we increase both the classification accuracy and the efficiency of the pose control. To test the efficiency of the LSTM on both tasks, the classification accuracy is computed while training the network on a varying number of glances. In addition to the final classification accuracy, the individual classification accuracies after each glance are evaluated. To demonstrate the efficiency of using a recurrent unit instead of a simple linear hidden layer, the experiment is repeated with the LSTM replaced by a linear layer of the same size (i.e., 256 neurons).
The second part of the evaluation is dedicated to the pose control by the location network. We evaluate it during the learning process, and compare the results against a model with a random location choice. To this end, we omit the location network and provide the model with new locations x ∈ [−1, 1] and orientations φ ∈ [−π/2, π/2] that are sampled from a uniform distribution. For training, only the classification part of Eq (6) is used to create the weight update, while β is set to 0.
In the third part of the evaluation, the different approaches for combining the tactile information with its corresponding location (What & Where) are compared.
All models are trained for 50 ⋅ 103 steps. In order to measure the performance after a certain number of training steps, the training is stopped. This is followed by estimation of the mean classification accuracy of 100 newly generated batches, using the currently available policy. In our experiments, the “classification accuracy” or “classification performance” is defined as the probability of the model to correctly classify the current object. To obtain a statistically correct measure of the accuracy, each experiment is repeated 10 times. For the final evaluation, the mean accuracy of these experiments is computed with the standard deviation of the mean as the accuracy measure error.
Hyperparameters
Table 1 lists the hyperparameters that are used for all experiments. The parameters are chosen according to random search [38] with a fixed number of 3 glances, followed by additional manual tuning. The weights of all layers are initialized using He normal initialization [39] with a bias of 0.
Creation of the dataset
In order to perform quick optimization and testing, we conducted multiple experiments on a pre-recorded dataset D o (see S1 Dataset) generated in Gazebo, previous to the experimental runs, for each object o. The dataset contains tuples d o = ( x , φ , p → ). Here p → is the normalized pressure-vector p →, x ∈ [−1, 1] the respective position of the sensor within the location space and φ ∈ [−π/2, π/2] the angle. For each object the recording of the tuples do starts with the position x = −1 and the orientation φ = −π/2. These two parameters are then both incremented with a step size of Δx = 0.01 and Δφ = π ⋅ 0.01, leading to 201 × 201 prerecorded data-points do for each object. The complete dataset has then a size of roughly 161 ⋅ 103 data-points that can be picked to approximate the sensor pose generated by the location network. For a new pair (x, φ) generated by the network, the closest data-point do is selected from the pre-recorded data set.
Results
The main results of the conducted experiments are summarized in Table 2. It displays the classification accuracies for all three variants of the architecture as described above and shows the corresponding results for an increasing number of glances. The full meta-controller model π M contains all trained components including the LSTM module and the location network. The random location policy approach πrloc substitutes the location network with a random location generator. πMLP substitutes the LSTM unit with a linear layer of the same size with a ReLu as its activation function. As the neural network is now built out of linear layers only, it can be seen as a multi-layer perceptron (MLP). In the last column, labeled 〈πMLP〉, the classification performance of πMLP is evaluated by averaging over all conducted glances.
The “full model” π M (see column 1) reaches a classification accuracy of about 99.4% on the pre-recorded dataset. While the accuracy using one random glance is only ≈ 55%, it continuously improves when more glances can be executed. Granting the model just one more glance leads to an accuracy of about 83%. Overall, accuracy improvement for the full model is faster than for the other two tested architectures, up to its convergence after about 6 glances are performed.
Column 2 presents the results of the random location policy. It starts from the same performance as the full model (since the first glance is random in both policies) and from there approaches its asymptotic performance more slowly, making its performance inferior when only 2 to 6 glances can be invested. Thus, our model is able to learn to efficiently extract important information when the number of possible interactions with the given object are limited.
If the recurrent LSTM unit is replaced with a linear layer of the same size (column 3), the classification accuracy does not rise beyond 67%, constituting the worst result. Due to missing recurrent connection, and the fact that the accuracy is evaluated only after the last glance, the MLP-based architecture πMLP is optimized based only on the last glance, and therefore does not improve after two glances.
However, by averaging its output according to
Fig 7 shows the time course of learning of the model for the different numbers of performed glances. Additionally, the individual classification accuracy for each glance within one classification event that uses 10 glances is visualized in Fig 8. The accuracy of the individual glances within a classification event differs from the ones in Fig 7.
Fig 9 presents a detailed performance comparison between the πrloc and the full model π M. Here, one can again see that a huge performance gap exists when the model is able to execute only a small number of glances and that this gap is progressively closed as the number of glances is increased. Fig 9 shows that the impact of the learned location policy is more visible when the model is trained on a smaller number of glances. The model π M learns to classify objects based on limited information more efficiently.
Table 3 lists the best classification accuracies of the model using 3 glances for the different ways of combining the normalized pressure vector p → with the corresponding location l →. The procedure to combine the two sets of features via concatenation and then processing the result through two layers gives slightly better results than the element-wise addition, but clearly outperforms the approaches of element-wise multiplication and the concatenation approach using one layer.
Discussion
The performed evaluations demonstrated that the proposed model is able to classify the objects with an accuracy of nearly 100% by actively acquiring an optimized sequence of tactile sensor measurements. In this approach the data is generated on-the-fly by haptic interaction with the environment, performed by means of haptic glances and directed by the history of previous tactile events. The results of the conducted experiments show that the full network architecture π M, including the recurrent LSTM network and the location network, is capable of controlling the execution of haptic glances in the most efficient way. The architecture performs better with a trained location network than with a random location policy πrloc. Employing the LSTM to represent the sequence history yields better performance in comparison to the memory-less architecture πMLP. Here, the location network only slightly improves the location w.r.t. the task-relevant information with the increasing number of glances. In comparison with π M, a good but less efficient performance of the 〈πMLP〉 that accumulates individual classification decisions may be due to the averaging out of noise with the increasing number of glances. Therefore, both recurrence and an optimized location control are likely to be necessary ingredients of an efficient haptic exploration model in our scenario. These results may be constrained by the simplicity of the 3D shapes considered in the experiment. For an extensive evaluation of the proposed approach, the creation of data sets with a greater number of different objects would be necessary, including stimuli that are more challenging to differentiate without an optimized control strategy. For the described case, we expect that the efficiency and accuracy trends would become more evident.
The network architecture π M merely fuses and accumulates the data, whose representation is optimized with the goal to achieve the most accurate and efficient execution for a given task. Therefore, it provides a general interface, which has a capacity to accommodate for different types of haptic glance parameterizations. However, our approach to parameterization and control was deliberately very rudimentary in this work. The currently employed minimalistic haptic glance is controlled by a one-dimensional translation and rotation, characterized by a uni-variate pressure output. This simplification was coupled to the experimental design targeting exploration of one-dimensional curvature features. Other types of haptic glance controller parameterizations are desirable, in case other features than the curvature need to be explored. On the one hand, both the number, type of the control parameters and the outputs are very likely to be determined bottom-up by the features of the 3D environment in which haptic interaction is performed. On the other hand, they are determined in a top-down fashion by the task of the interaction. It remains an open question how to automatically derive the minimal parameterization and the output of the haptic glance controller depending on the features of the environment, the task, the available degrees of freedom of the employed device and its tactile capabilities.
The modularity of our model should, however, provide the functionality to adapt to more complex sensor devices as different modules of the HAM just have to be extended to cope with the increasing number of control dimensions. In the current configuration, our model has a total number of 741248 trainable weights. Within the simplest case, for each additional trainable parameter that is provided to the low-level haptic glance controller an additional output stream with at least one additional linear layer (with e.g. 64 neurons) has to be added to the location network. While this procedure does not necessarily lead to a significant increase in the number of trainable weights, too many additional control parameters might exceed the memory and processing capacity of the LSTM network. The LSTM network contains—in contrast to the linear layers—a large amount of the trainable weights. A necessary amplification of its size or the addition of a second LSTM network in order to increase performance might have a higher impact on the model’s size and its training time. While the designed hybrid loss might be a reasonable approach when only two control parameters have to be adapted, a higher number could slow down the convergence process of the model. One possible way out of this dilemma might be to separately train the classification and control part of the HAM with different loss functions that share the achieved reward.
Conclusion and future work
In this work we have proposed the first implementation of a controller, inspired by the concept of haptic glances. Provided a pose parameter as an input, a floating tactile sensor array touches the surface at the specified location and yields the resulting pressure vector. We have trained a meta-controller network architecture to perform an efficient haptic exploration of 3D shapes by optimally parametrizing the haptic glance controller to perform a sequence of glances and identify 3D objects. Tests of the architecture have been successfully performed in a physics-driven simulation environment.
The structure of the meta-controller includes a mechanism that accumulates the data acquired during execution of the task and parameterizes the future haptic glances based on the optimized representation of this data. However, the current mechanism performing this temporal integration—based on an LSTM and inspired by the functionality of the working memory—may not be sufficient for an execution of a more complex task consisting of multiple task stages, such as e.g. haptic search, or a contact-rich object manipulation. In such tasks, it may be necessary to save the representation of data existing in the working memory to a long-term memory, from which this information could be retrieved at a later stage in the task execution. To this end, the meta-controller needs to communicate with an extra structure, based on e.g. hashing, such as Neural Turing Machine [40] to access features acquired at multiple previous time slots during interaction with the target topology.
To support our claim that the resulting policy can enable a robot equipped with a tactile sensor to perform efficient object identification by touch, we see performing tests with a (simulated) robot platform, equipped with a Myrmex tactile sensor array as our next task. Furthermore, we will extend our experimental design with the second curvature dimension and, corresponding to this, an extra degree of freedom in our haptic glance controller.
Due to the fact that the pose is sampled from a Gaussian distribution, it is highly unlikely that the same position or orientation is sustained during the exploration. Therefore, the current approach results in a jumpy energy-inefficient exploration trajectory which makes a more energy-efficient policy desirable. Consequently, the meta-controller optimization should be extended to enable a smoother trajectory generation. This may be possible by a careful shaping of the reward function or a further refinement of the location network.
Beyond performing haptic object identification, we believe that the developed procedure may be applied to enable a robot to perform complex manipulation tasks that heavily rely on haptics. Execution of a more complex tasks such as above-mentioned haptic search commonly involve multiple types of strategies, targeting exploration of different types of haptic features, e.g. movability or rigidity. This may be possible by implementing a set of low-level haptic glance controllers characterized by different parameterizations and outputs accompanied by a gating mechanism that enables the overall model to switch between them.
Supporting information
S1 Code [docx]
Gazebo.
S2 Code [docx]
Myrmex simulation.
S3 Code [docx]
ROS.
S4 Code [docx]
The “hand of god” plugin.
S5 Code [docx]
The haptic attention model.
S1 Video [mp4]
Contact information in Gazebo.
S2 Video [docx]
Modular Haptic Stimulus Board (MHSB).
S3 Video [mp4]
Gazebo simulation—Haptic glance controller.
S1 Project [docx]
Modular Haptic Stimulus Board (MHSB).
S1 Dataset [docx]
Recorded dataset of glance locations and the corresponding pressure data.
Zdroje
1. Szegedy C, Liu W, Jia Y, Sermanet P, Reed SE, Anguelov D, et al. Going Deeper with Convolutions. CoRR. 2014;abs/1409.4842.
2. He K, Zhang X, Ren S, Sun J. Deep Residual Learning for Image Recognition. CoRR. 2015;abs/1512.0.
3. Levine S, Pastor P, Pastor P, Krizhevsky A, Ibarz J, Ibarz J, et al. Learning hand-eye coordination for robotic grasping with deep learning and large-scale data collection. The International Journal of Robotics Research. 2017;37(4-5):421–436. doi: 10.1177/0278364917710318
4. Okamura A, Cutkosky M. Feature Detection for Haptic Exploration with Robotic Fingers. vol. 20; 2001.
5. Martins R, Ferreira JF, Dias J. Touch attention Bayesian models for robotic active haptic exploration of heterogeneous surfaces. CoRR. 2014;abs/1409.6.
6. Tian S, Ebert F, Jayaraman D, Mudigonda M, Finn C, Calandra R, et al. Manipulation by Feel: Touch-Based Control with Deep Predictive Models. arxiv. 2019;.
7. Lee MA, Zhu Y, Srinivasan K, Shah P, Savarese S, Fei-Fei L, et al. Making Sense of Vision and Touch: Self-Supervised Learning of Multimodal Representations for Contact-Rich Tasks. arxiv. 2019;.
8. Kalagher H, Jones SS. Young children’s haptic exploratory procedures. Journal of Experimental Child Psychology. 2011;110(4):592–602. https://doi.org/10.1016/j.jecp.2011.06.007 21783203
9. Klatzky RL, Lederman SJ, Mankinen JM. Visual and haptic exploratory procedures in children’s judgments about tool function. The Development of Haptic Perception. 2005;28(3):240–249.
10. Klatzky RL, Lederman SJ, Reed CL. There’s more to touch than meets the eye: the salience of object attributes for hpatics with and without vision. Journal of Experimental Psychology. 1987;.
11. Klatzky RL, Lederman SJ. Identifying objects from a haptic glance. Perception & Psychophysics. 1995;57(8):1111–1123. doi: 10.3758/BF03208368
12. Fishel JA, Loeb GE. Bayesian Exploration for Intelligent Identification of Textures. Frontiers in Neurorobotics. 2012;6. doi: 10.3389/fnbot.2012.00004
13. Chu V, McMahon I, Riano L, McDonald CG, He Q, Perez-Tejada JM, et al. Using robotic exploratory procedures to learn the meaning of haptic adjectives. In: 2013 IEEE International Conference on Robotics and Automation (ICRA). IEEE; 2013. p. 3048–3055.
14. Chu V, McMahon I, Riano L, McDonald CG, He Q, Perez-Tejada JM, et al. Robotic learning of haptic adjectives through physical interaction. Robotics and Autonomous Systems. 2015;63 : 279–292. https://doi.org/10.1016/j.robot.2014.09.021
15. Pape L, Oddo CM, Controzzi M, Cipriani C, Förster A, Carrozza MC, et al. Learning tactile skills through curious exploration. Frontiers in Neurorobotics. 2012;6. doi: 10.3389/fnbot.2012.00006 22837748
16. Sutton RS, Barto AG. Reinforcement learning: An introduction. second edtion ed. MIT Press; 2018.
17. van Hoof H, Hermans T, Neumann G, Peters J. Learning robot in-hand manipulation with tactile features. In: 2015 IEEE-RAS 15th International Conference on Humanoid Robots (Humanoids); 2015. p. 121–127.
18. Rajeswaran A, Kumar V, Gupta A, Schulman J, Todorov E, Levine S. Learning Complex Dexterous Manipulation with Deep Reinforcement Learning and Demonstrations. CoRR. 2017;abs/1709.10087.
19. Mnih V, Heess N, Graves A, Kavukcuoglu K. Recurrent Models of Visual Attention. CoRR. 2014;abs/1406.6247.
20. Ba J, Mnih V, Kavukcuoglu K. Multiple Object Recognition with Visual Attention. CoRR. 2014;abs/1412.7755.
21. Hayhoe M, Ballard D. Eye movements in natural behavior. Trends in Cognitive Sciences. 2005;9(4):188–194. doi: 10.1016/j.tics.2005.02.009 15808501
22. Mathe S, Sminchisescu C. Action from still image dataset and inverse optimal control to learn task specific visual scanpaths. In: Advances in neural information processing systems; 2013. p. 1923–1931.
23. Itti L, Koch C, Niebur E. A model of saliency-based visual attention for rapid scene analysis. IEEE Transactions on pattern analysis and machine intelligence. 1998;20(11):1254–1259. doi: 10.1109/34.730558
24. Itti L, Koch C. Computational modelling of visual attention. Nature Reviews Neuroscience. 2001;2(3):194–203. doi: 10.1038/35058500 11256080
25. Schurmann C, Koiva R, Haschke R, Ritter H. A modular high-speed tactile sensor for human manipulation research. In: 2011 IEEE World Haptics Conference (WHC 2011). IEEE; 2011. p. 339–344.
26. Moringen A, Krieger K, Haschke R, Ritter H. Haptic Search for Complex 3D Shapes Subject to Geometric Transformations or Partial Occlusion. In: IEEE World Haptics; 2017.
27. Krieger K, Moringen A, Haschke R, Ritter H. Shape Features of the Search Target Modulate Hand Velocity, Posture and Pressure during Haptic Search in a 3D Display. In: Lecture Notes in Computer Science. Springer; 2016.
28. Moringen A, Haschke R, Ritter H. Search Procedures during Haptic Search in an Unstructured 3D Display. In: IEEE Haptics Symposium; 2016.
29. Williams RJ. Toward a theory of reinforcement-learning connectionist systems. Technical Report NU-CCS-88-3, Northeastern University. 1988;.
30. Williams RJ. Simple statistical gradient-following algorithms for connectionist reinforcement learning. Machine Learning. 1992;8(3-4):229–256. doi: 10.1007/BF00992696
31. Hochreiter S, Schmidhuber J. Long short-term memory. MIT Press. 1997;9(8):1735–1780.
32. Krizhevsky A, Sutskever I, Hinton GE. Imagenet classification with deep convolutional neural networks. In: Advances in neural information processing systems; 2012. p. 1097–1105.
33. Goodfellow I, Bengio Y, Courville A. Deep learning. MIT press; 2016.
34. Larochelle H, Hinton GE. Learning to combine foveal glimpses with a third-order Boltzmann machine. In: Lafferty JD, Williams CKI, Shawe-Taylor J, Zemel RS, Culotta A, editors. Advances in Neural Information Processing Systems 23. Curran Associates, Inc.; 2010. p. 1243–1251.
35. Dugas C, Bengio Y, Bélisle F, Nadeau C, Garcia R. Incorporating second-order functional knowledge for better option pricing. In: Advances in neural information processing systems; 2001. p. 472–478.
36. Nesterov Y. A method for solving the convex programming problem with convergence rate O(1/k2). In: Dokl. Akad. Nauk SSSR; 1983. p. 543–547.
37. Nesterov Y. Introductory Lectures on Convex Optimization: A Basic Course. Applied Optimization. Springer US; 2013.
38. Bergstra J, Bengio Y. Random search for hyper-parameter optimization. Journal of Machine Learning Research. 2012;13(Feb):281–305.
39. He K, Zhang X, Ren S, Sun J. Delving deep into rectifiers: Surpassing human-level performance on imagenet classification. In: Proceedings of the IEEE international conference on computer vision; 2015. p. 1026–1034.
40. Graves A, Wayne G, Danihelka I. Neural Turing Machines. CoRR. 2014;abs/1410.5401.
Článok vyšiel v časopise
PLOS One
2020 Číslo 1
- Masturbační chování žen v ČR − dotazníková studie
- Naděje budí časná diagnostika Parkinsonovy choroby založená na pachu kůže
- Je Fuchsova endotelová dystrofie rohovky neurodegenerativní onemocnění?
- Dieta MIND zpomaluje stárnutí mozku
- Účastník studie fáze I po dvou dnech ve stadiu klinické smrti zemřel
-
Všetky články tohto čísla
- ETAPOD: A forecast model for prediction of black pod disease outbreak in Nigeria
- Disparate effects of antibiotic-induced microbiome change and enhanced fitness in Daphnia magna
- Deliver on Your Own: Disrespectful Maternity Care in rural Kenya
- Number of days required to estimate physical activity constructs objectively measured in different age groups: Findings from three Brazilian (Pelotas) population-based birth cohorts
- Exploring the mechanism of olfactory recognition in the initial stage by modeling the emission spectrum of electron transfer
- Risk of complications among diabetics self-reporting oral health status in Canada: A population-based cohort study
- Practical considerations in the use of a porcine model (Sus scrofa domesticus) to assess prevention of postoperative peritubal adhesions
- Transcriptional Differences in Peanut (Arachis hypogaea L.) Seeds at the Freshly Harvested, After-ripening and Newly Germinated Seed Stages: Insights into the Regulatory Networks of Seed Dormancy Release and Germination
- Identifying maintenance hosts for infection with Dichelobacter nodosus in free-ranging wild ruminants in Switzerland: A prevalence study
- Model order reduction for left ventricular mechanics via congruency training
- Production, purification and evaluation of biodegradation potential of PHB depolymerase of Stenotrophomonas sp. RZS7
- The impact of a wireless audio system on communication in robotic-assisted laparoscopic surgery: A prospective controlled trial
- Seroprevalence of viral and vector-borne bacterial pathogens in domestic dogs (Canis familiaris) in northern Botswana
- Musical expertise generalizes to superior temporal scaling in a Morse code tapping task
- Cross-cultural adaptation and psychometric evaluation of the Yoruba version of Oswestry disability index
- Post-transcriptional regulation of Rad51c by miR-222 contributes cellular transformation
- Can scientists fill the science journalism void? Online public engagement with science stories authored by scientists
- Retention and predictors of attrition among patients who started antiretroviral therapy in Zimbabwe’s national antiretroviral therapy programme between 2012 and 2015
- Prognostics for pain in osteoarthritis: Do clinical measures predict pain after total joint replacement?
- Effects of Transcranial Direct Current Stimulation on GABA and Glx in Children: A pilot study
- Evaluation of rice wild relatives as a source of traits for adaptation to iron toxicity and enhanced grain quality
- Brief communication: Long-term absence of Langerhans cells alters the gene expression profile of keratinocytes and dendritic epidermal T cells
- APOBEC3B reporter myeloma cell lines identify DNA damage response pathways leading to APOBEC3B expression
- Morphological diversity within a core collection of subterranean clover (Trifolium subterraneum L.): Lessons in pasture adaptation from the wild
- Feasibility of real-time in vivo 89Zr-DFO-labeled CAR T-cell trafficking using PET imaging
- Repository-based plasmid design
- A new method of recording from the giant fiber of Drosophila melanogaster shows that the strength of its auditory inputs remains constant with age
- Aberrant cervical innate immunity predicts onset of dysbiosis and sexually transmitted infections in women of reproductive age
- Safe mobility, socioeconomic inequalities, and aging: A 12-year multilevel interrupted time-series analysis of road traffic death rates in a Latin American country
- THAP11F80L cobalamin disorder-associated mutation reveals normal and pathogenic THAP11 functions in gene expression and cell proliferation
- Lesion of striatal patches disrupts habitual behaviors and increases behavioral variability
- A clinical method for estimating the modulus of elasticity of the human cornea in vivo
- Patient perceived value of teleophthalmology in an urban, low income US population with diabetes
- Evidence in support of chromosomal sex influencing plasma based metabolome vs APOE genotype influencing brain metabolome profile in humanized APOE male and female mice
- Accelerated sparsity based reconstruction of compressively sensed multichannel EEG signals
- Microvesicles from Lactobacillus reuteri (DSM-17938) completely reproduce modulation of gut motility by bacteria in mice
- Dense carbon-nanotube coating scaffolds stimulate osteogenic differentiation of mesenchymal stem cells
- Gamma Knife radiosurgery for vestibular schwannomas: Evaluation of planning using the sphericity degree of the target volume
- Purification and molecular characterization of phospholipase, antigen 5 and hyaluronidases from the venom of the Asian hornet (Vespa velutina)
- Why are animal source foods rarely consumed by 6-23 months old children in rural communities of Northern Ethiopia? A qualitative study
- A study to better understand under-utilization of laboratory tests for antenatal care in Senegal
- Physicians’ perspectives regarding non-medical switching of prescription medications: Results of an internet e-survey
- Effectiveness of information technology–enabled ‘SMART Eating’ health promotion intervention: A cluster randomized controlled trial
- Cauda Equina Syndrome Core Outcome Set (CESCOS): An international patient and healthcare professional consensus for research studies
- A new species of Macrocypraea (Gastropoda, Cypraeidae) from Trindade Island, Brazil, including phenotypic differentiation from remaining congeneric species
- Long term conjugated linoleic acid supplementation modestly improved growth performance but induced testicular tissue apoptosis and reduced sperm quality in male rabbit
- A new approach to the temporal significance of house orientations in European Early Neolithic settlements
- Persistence of chikungunya ECSA genotype and local outbreak in an upper medium class neighborhood in Northeast Brazil
- In vivo elongation of thin filaments results in heart failure
- Disparity in depressive symptoms between heterosexual and sexual minority men in China: The role of social support
- Effect of classroom intervention on student food selection and plate waste: Evidence from a randomized control trial
- Mating strategy is determinant of adenovirus prevalence in European bats
- Preventing HIV and HSV-2 through knowledge and attitudes: A replication study of a multi-component community-based intervention in Zimbabwe
- Randomized clinical trial analyzing maintenance of peripheral venous catheters in an internal medicine unit: Heparin vs. saline
- Patient-related factors may influence nursing perception of sleep in the Intensive Care Unit
- A randomized trial of a behavioral intervention to decrease hospital length of stay by decreasing bedrest
- Color image segmentation using adaptive hierarchical-histogram thresholding
- The role of demographic history and selection in shaping genetic diversity of the Galápagos penguin (Spheniscus mendiculus)
- Attitudes towards animal study registries and their characteristics: An online survey of three cohorts of animal researchers
- Risk perception and behavioral change during epidemics: Comparing models of individual and collective learning
- Risk factors for third-generation cephalosporin resistant Enterobacteriaceae in gestational urine cultures: A retrospective cohort study based on centralized electronic health records
- Residential neighbourhood greenspace is associated with reduced risk of cardiovascular disease: A prospective cohort study
- Potential socioeconomic impacts from ocean acidification and climate change effects on Atlantic Canadian fisheries
- Prevention and control of cholera with household and community water, sanitation and hygiene (WASH) interventions: A scoping review of current international guidelines
- Female finches prefer courtship signals indicating male vigor and neuromuscular ability
- The effect of spatial position and age within an egg-clutch on embryonic development and key metabolic enzymes in two clownfish species, Amphiprion ocellaris and Amphiprion frenatus
- The impact of translated reminder letters and phone calls on mammography screening booking rates: Two randomised controlled trials
- Application of a genetic algorithm to the keyboard layout problem
- Design and evaluation of a laboratory-based wheelchair castor testing protocol using community data
- Relationship between diabetic macular edema and choroidal layer thickness
- Evaluation of the predictive ability of ultrasound-based assessment of breast cancer using BI-RADS natural language reporting against commercial transcriptome-based tests
- A Comprehensive Data Gathering Network Architecture in Large-Scale Visual Sensor Networks
- Recovery of health-related quality of life after burn injuries: An individual participant data meta-analysis
- Modeling aggressive market order placements with Hawkes factor models
- Role of ecology in shaping external nasal morphology in bats and implications for olfactory tracking
- High expression of olfactomedin-4 is correlated with chemoresistance and poor prognosis in pancreatic cancer
- Development and validation of a prognostic model predicting symptomatic hemorrhagic transformation in acute ischemic stroke at scale in the OHDSI network
- Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction
- Tofu intake is inversely associated with risk of breast cancer: A meta-analysis of observational studies
- Influence of light on the infection of Aureococcus anophagefferens CCMP 1984 by a “giant virus”
- Temporal ordering of input modulates connectivity formation in a developmental neuronal network model of the cortex
- Healthy lifestyle index and its association with hypertension among community adults in Sri Lanka: A cross-sectional study
- From organ to cell: Multi-level telomere length assessment in patients with idiopathic pulmonary fibrosis
- How do critical care staff respond to organisational challenge? A qualitative exploration into personality types and cognitive processing in critical care
- Effects of supplemental creatine and guanidinoacetic acid on spatial memory and the brain of weaned Yucatan miniature pigs
- Community-Based Health Planning and Services Plus programme in Ghana: A qualitative study with stakeholders in two Systems Learning Districts on improving the implementation of primary health care
- An investigation of transportation practices in an Ontario swine system using descriptive network analysis
- Comparison of gridded precipitation datasets for rainfall-runoff and inundation modeling in the Mekong River Basin
- Functional interactions in patients with hemianopia: A graph theory-based connectivity study of resting fMRI signal
- The effects of dual-task cognitive interference on gait and turning in Huntington’s disease
- Effects of Allium hookeri on gut microbiome related to growth performance in young broiler chickens
- Novel imaging biomarkers for mapping the impact of mild mitochondrial uncoupling in the outer retina in vivo
- Hyperkalemia treatment modalities: A descriptive observational study focused on medication and healthcare resource utilization
- Long term impact of PositiveLinks: Clinic-deployed mobile technology to improve engagement with HIV care
- Comparison of post-transplantation diabetes mellitus incidence and risk factors between kidney and liver transplantation patients
- A definition-by-example approach and visual language for activity patterns in engineering disciplines
- A network analysis revealed the essential and common downstream proteins related to inguinal hernia
- Use of conventional cardiac troponin assay for diagnosis of non-ST-elevation myocardial infarction: ‘The Ottawa Troponin Pathway’
- Identification and characterization of miRNAs involved in cold acclimation of zebrafish ZF4 cells
- Research on motion planning for an indoor spray arm based on an improved potential field method
- Detailed analysis of the transverse arch of hallux valgus feet with and without pain using weightbearing ultrasound imaging and precise force sensors
- Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling
- Apolipoprotein-AI mimetic peptides D-4F and L-5F decrease hepatic inflammation and increase insulin sensitivity in C57BL/6 mice
- Treating patients with driving phobia by virtual reality exposure therapy – a pilot study
- Efficient processing of raster and vector data
- Therapeutic hypothermia after out of hospital cardiac arrest improve 1-year survival rate for selective patients
- Carotid plaques and neurological impairment in patients with acute cerebral infarction
- Deep learning based image reconstruction algorithm for limited-angle translational computed tomography
- Association between coffee drinking and telomere length in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
- Hyperbaric oxygen preconditioning and the role of NADPH oxidase inhibition in postischemic acute kidney injury induced in spontaneously hypertensive rats
- Rad51 paralogs and the risk of unselected breast cancer: A case-control study
- Diagnostic differences in respiratory breathing patterns and work of breathing indices in children with Duchenne muscular dystrophy
- The role of narrative in collaborative reasoning and intelligence analysis: A case study
- Proportions of CD4 test results indicating advanced HIV disease remain consistently high at primary health care facilities across four high HIV burden countries
- Modelling of amino acid turnover in the horse during training and racing: A basis for developing a novel supplementation strategy
- Single-modal and multi-modal false arrhythmia alarm reduction using attention-based convolutional and recurrent neural networks
- Eye-gaze information input based on pupillary response to visual stimulus with luminance modulation
- Trends of litter decomposition and soil organic matter stocks across forested swamp environments of the southeastern US
- Post mortem evaluation of inflammation, oxidative stress, and PPARγ activation in a nonhuman primate model of cardiac sympathetic neurodegeneration
- Were ancient foxes far more carnivorous than recent ones?—Carnassial morphological evidence
- Disruption in daily eating-fasting and activity-rest cycles in Indian adolescents attending school
- Plasma proteome profiling of freshwater and seawater life stages of rainbow trout (Oncorhynchus mykiss)
- Percent amplitude of fluctuation: A simple measure for resting-state fMRI signal at single voxel level
- Antimicrobial activity of Asteraceae species against bacterial pathogens isolated from postmenopausal women
- Are changes in depressive symptoms, general health and residential area socio-economic status associated with trajectories of waist circumference and body mass index?
- Extracellular vesicles of U937 macrophage cell line infected with DENV-2 induce activation in endothelial cells EA.hy926
- Link-centric analysis of variation by demographics in mobile phone communication patterns
- Tobacco smoking and health-related quality of life among university students: Mediating effect of depression
- The Shapley value for a fair division of group discounts for coordinating cooling loads
- Incidence of hospital-acquired pressure ulcers in patients with "minimal risk" according to the "Norton-MI" scale
- Lipoprotein(a) plasma levels are not associated with survival after acute coronary syndromes: An observational cohort study
- Use of Nanotrap particles for the capture and enrichment of Zika, chikungunya and dengue viruses in urine
- Pancreatic secretory trypsin inhibitor reduces multi-organ injury caused by gut ischemia/reperfusion in mice
- Biochemical characterization of Ty1 retrotransposon protease
- Lateral pressure equalisation as a principle for designing support surfaces to prevent deep tissue pressure ulcers
- The validation of the Beijing version of the Montreal Cognitive Assessment in Chinese patients undergoing hemodialysis
- Inflammasome expression is higher in ovarian tumors than in normal ovary
- HCV genotype profile in Brazil of mono-infected and HIV co-infected individuals: A survey representative of an entire country
- Engaging with change: Information and communication technology professionals’ perspectives on change at the mid-point in the UK/EU Brexit process
- Adherence to iron-folic acid supplement and associated factors among antenatal care attending pregnant mothers in governmental health institutions of Adwa town, Tigray, Ethiopia: Cross-sectional study
- Flower, seed, and fruit development in three Tunisian species of Polygonum: Implications for their taxonomy and evolution of distyly in Polygonaceae
- Development of a risk score for prediction of poor treatment outcomes among patients with multidrug-resistant tuberculosis
- Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virus
- Aqueous extract from Mangifera indica Linn. (Anacardiaceae) leaves exerts long-term hypoglycemic effect, increases insulin sensitivity and plasma insulin levels on diabetic Wistar rats
- Discovery of Jogalong virus, a novel hepacivirus identified in a Culex annulirostris (Skuse) mosquito from the Kimberley region of Western Australia
- Clinical, cytogenetic and molecular genetic characterization of a tandem fusion translocation in a male Holstein cattle with congenital hypospadias and a ventricular septal defect
- Detection of Torque Teno Virus (TTV) and TTV-Like Minivirus in patients with presumed infectious endophthalmitis in India
- CD4 rate of increase is preferred to CD4 threshold for predicting outcomes among virologically suppressed HIV-infected adults on antiretroviral therapy
- Estimating the basic reproduction number of a pathogen in a single host when only a single founder successfully infects
- What drugs modify the risk of iatrogenic impulse-control disorders in Parkinson’s disease? A preliminary pharmacoepidemiologic study
- Evaluating emotional distress and health-related quality of life in patients with heart failure and their family caregivers: Testing dyadic dynamics using the Actor-Partner Interdependence Model
- Community- and trophic-level responses of soil nematodes to removal of a non-native tree at different stages of invasion
- Association of ECG parameters with late gadolinium enhancement and outcome in patients with clinical suspicion of acute or subacute myocarditis referred for CMR imaging
- Catchment-scale export of antibiotic resistance genes and bacteria from an agricultural watershed in central Iowa
- Impact of multi-drug resistant bacteria on economic and clinical outcomes of healthcare-associated infections in adults: Systematic review and meta-analysis
- Characterization of a universal screening approach for congenital CMV infection based on a highly-sensitive, quantitative, multiplex real-time PCR assay
- Proof-of-concept for a non-invasive, portable, and wireless device for cardiovascular monitoring in pediatric patients
- On PTV definition for glioblastoma based on fiber tracking of diffusion tensor imaging data
- Genes associated with body weight gain and feed intake identified by meta-analysis of the mesenteric fat from crossbred beef steers
- Intraoperative computed tomography imaging for dose calculation in intraoperative electron radiation therapy: Initial clinical observations
- Human lung epithelial BEAS-2B cells exhibit characteristics of mesenchymal stem cells
- Simple non-mydriatic retinal photography is feasible and demonstrates retinal microvascular dilation in Chronic Obstructive Pulmonary Disease (COPD)
- Maternal depressive symptoms and children’s cognitive development: Does early childcare and child’s sex matter?
- Evaluation of a bioengineered ACL matrix’s osteointegration with BMP-2 supplementation
- Psychosocial profiles of physical activity fluctuation in office employees: A latent profile analysis
- Prevalence and characteristics of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) isolated from chicken meat in the province of Quebec, Canada
- Soluble AXL as a marker of disease progression and survival in melanoma
- Using machine learning methods to determine a typology of patients with HIV-HCV infection to be treated with antivirals
- Gender differences influence over insomnia in Korean population: A cross-sectional study
- Impact of scion/rootstock reciprocal effects on metabolomics of fruit juice and phloem sap in grafted Citrus reticulata
- Adapting cognitive diagnosis computerized adaptive testing item selection rules to traditional item response theory
- Autumn shifts in cold tolerance metabolites in overwintering adult mountain pine beetles
- Umbilical cord separation time, predictors and healing complications in newborns with dry care
- Analysis of attitudinal components towards statistics among students from different academic degrees
- Effects of fatigue induced by repeated-sprint on kicking accuracy and velocity in female soccer players
- A pre-clinical validation plan to evaluate analytical sensitivities of molecular diagnostics such as BD MAX MDR-TB, Xpert MTB/Rif Ultra and FluoroType MTB
- Leadership for success in transforming medical abortion policy in Canada
- Clinical correlates associated with the long-term response of bipolar disorder patients to lithium, valproate or lamotrigine: A retrospective study
- Forecasting stock prices with long-short term memory neural network based on attention mechanism
- On the genus Crossaster (Echinodermata: Asteroidea) and its distribution
- Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds
- An integrated vitamin E-coated polymer hybrid nanoplatform: A lucrative option for an enhanced in vitro macrophage retention for an anti-hepatitis B therapeutic prospect
- The effect of strontium and silicon substituted hydroxyapatite electrochemical coatings on bone ingrowth and osseointegration of selective laser sintered porous metal implants
- Molecular prevalence of Bartonella, Babesia, and hemotropic Mycoplasma species in dogs with hemangiosarcoma from across the United States
- Color discrimination and gas chromatography-mass spectrometry fingerprint based on chemometrics analysis for the quality evaluation of Schizonepetae Spica
- Comparisons of recurrence-free survival and overall survival between microwave versus radiofrequency ablation treatment for hepatocellular carcinoma: A multiple centers retrospective cohort study with propensity score matching
- Oral misoprostol, low dose vaginal misoprostol, and vaginal dinoprostone for labor induction: Randomized controlled trial
- The association between dietary patterns before and in early pregnancy and the risk of gestational diabetes mellitus (GDM): Data from the Malaysian SECOST cohort
- Dynamic Extreme Aneuploidy (DEA) in the vegetable pathogen Phytophthora capsici and the potential for rapid asexual evolution
- Assertive, trainable and older dogs are perceived as more dominant in multi-dog households
- Prediction of Uropathogens by Flow Cytometry and Dip-stick Test Results of Urine Through Multivariable Logistic Regression Analysis
- Interleukin 6 is increased in preclinical HNSCC models of acquired cetuximab resistance, but is not required for maintenance of resistance
- Impact of viral disease hypophagia on pig jejunal function and integrity
- Molecular evidence for horizontal transmission of chelonid alphaherpesvirus 5 at green turtle (Chelonia mydas) foraging grounds in Queensland, Australia
- Evaluation and validation of 2D biomechanical models of the knee for radiograph-based preoperative planning in total knee arthroplasty
- Soil-Transmitted Helminth infections reduction in Bhutan: A report of 29 years of deworming
- cagA gene EPIYA motif genetic characterization from Colombian Helicobacter pylori isolates: Standardization of a molecular test for rapid clinical laboratory detection
- Spectral characteristics of urine from patients with end-stage kidney disease analyzed using Raman Chemometric Urinalysis (Rametrix)
- Fast quantitative time lapse displacement imaging of endothelial cell invasion
- Two novel mutations in MSX1 causing oligodontia
- Dome-shaped macula in children and adolescents
- Targeted transcriptomic study of the implication of central metabolic pathways in mannosylerythritol lipids biosynthesis in Pseudozyma antarctica T-34
- Preliminary evidences of the presence of extracellular DNA single stranded forms in soil
- A comparison of quality of life between patients treated with different dialysis modalities in Taiwan
- Comparison of Monocyte Distribution Width (MDW) and Procalcitonin for early recognition of sepsis
- Morphological association between the muscles and bones in the craniofacial region
- Transcriptome analysis of Actinidia chinensis in response to Botryosphaeria dothidea infection
- Comparative study on skin protection activity of polyphenol-rich extract and polysaccharide-rich extract from Sargassum vachellianum
- Real-world data about emotional stress, disability and need for social care in a German IBD patient cohort
- The regenerative compatibility: A synergy between healthy ecosystems, environmental attitudes, and restorative experiences
- Antenatal depression and its association with adverse birth outcomes in low and middle-income countries: A systematic review and meta-analysis
- Perceptions of risk and influences of choice in pregnant women with obesity. An evidence synthesis of qualitative research
- The role of refugee and migrant migration status on medication adherence: Mediation through illness perceptions
- Sexual risk classes among youth experiencing homelessness: Relation to childhood adversities, current mental symptoms, substance use, and HIV testing
- Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells
- Novel broad-spectrum activity-based probes to profile malarial cysteine proteases
- Association between opioid analgesic therapy and initiation of buprenorphine management: An analysis of prescription drug monitoring program data
- Effect of a community-based approach of iron and folic acid supplementation on compliance by pregnant women in Kiambu County, Kenya: A quasi-experimental study
- Improvement project in higher education institutions: A BPEP-based model
- An updated evaluation of serum sHER2, CA15.3, and CEA levels as biomarkers for the response of patients with metastatic breast cancer to trastuzumab-based therapies
- Genome-wide association study of metabolic syndrome in Korean populations
- Drug therapy problems and treatment satisfaction among ambulatory patients with epilepsy in a specialized hospital in Ethiopia
- Plasma kynurenines and prognosis in patients with heart failure
- Occurrence and distribution of anthropogenic persistent organic pollutants in coastal sediments and mud shrimps from the wetland of central Taiwan
- Intensified visual clutter induces increased sympathetic signalling, poorer postural control, and faster torsional eye movements during visual rotation
- Gut microbiota composition alterations are associated with the onset of diabetes in kidney transplant recipients
- Shock index and TIMI risk index as valuable prognostic tools in patients with acute coronary syndrome complicated by cardiogenic shock
- Merit overrules theory of mind when young children share resources with others
- Metabolic analysis of amino acids and vitamin B6 pathways in lymphoma survivors with cancer related chronic fatigue
- Immunopathogenesis of canine chronic ulcerative stomatitis
- Generalizing findings from a randomized controlled trial to a real-world study of the iLookOut, an online education program to improve early childhood care and education providers’ knowledge and attitudes about reporting child maltreatment
- When and what to test for: A cost-effectiveness analysis of febrile illness test-and-treat strategies in the era of responsible antibiotic use
- Comparison of effects and safety in providing controlled hypotension during surgery between dexmedetomidine and magnesium sulphate: A meta-analysis of randomized controlled trials
- The gene encoding the ketogenic enzyme HMGCS2 displays a unique expression during gonad development in mice
- Efficacy of a mitochondrion-targeting agent for reducing the level of urinary protein in rats with puromycin aminonucleoside-induced minimal-change nephrotic syndrome
- Association of endothelial nitric oxide synthase (NOS3) gene polymorphisms with primary open-angle glaucoma in a Saudi cohort
- Antitrust analysis with upward pricing pressure and cost efficiencies
- Natural selection contributes to food web stability
- Pyramiding QTLs controlling tolerance against drought, salinity, and submergence in rice through marker assisted breeding
- Diversity and plant growth-promoting functions of diazotrophic/N-scavenging bacteria isolated from the soils and rhizospheres of two species of Solanum
- Sofosbuvir-based regimen for genotype 2 HCV infected patients in Taiwan: A real world experience
- The virulence domain of Shigella IcsA contains a subregion with specific host cell adhesion function
- Sequencing artifacts derived from a library preparation method using enzymatic fragmentation
- Quantitative analysis of adsorption and desorption of volatile organic compounds on reusable zeolite filters using gas chromatography
- Quo vadis Pantanal? Expected precipitation extremes and drought dynamics from changing sea surface temperature
- Cloud-computing and machine learning in support of country-level land cover and ecosystem extent mapping in Liberia and Gabon
- The Brief Measure of Emotional Preoperative Stress (B-MEPS) as a new predictive tool for postoperative pain: A prospective observational cohort study
- The impact of diabetes mellitus medication on the incidence of endogenous endophthalmitis
- Correction: Chl1 DNA helicase and Scc2 function in chromosome condensation through cohesin deposition
- Clinical and pathological features of thrombotic microangiopathy influencing long-term kidney transplant outcomes
- Occupational exposure to particulate matter from air pollution in the outdoor workplaces in Almaty during the cold season
- Morphological adjustment in free-living Steinernema feltiae infective juveniles to increasing concentration of Nemafric-BL phytonematicide
- Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis
- Concurrent lipidomics and proteomics on malignant plasma cells from multiple myeloma patients: Probing the lipid metabolome
- Retraction: SDR9C7 Promotes Lymph Node Metastases in Patients with Esophageal Squamous Cell Carcinoma
- Association between tuberculosis and depression on negative outcomes of tuberculosis treatment: A systematic review and meta-analysis
- Bioluminescent imaging of Arabidopsis thaliana using an enhanced Nano-lantern luminescence reporter system
- Biosynthetic pathway of indole-3-acetic acid in ectomycorrhizal fungi collected from northern Thailand
- Sex-specific and opposite modulatory aspects revealed by PPI network and pathway analysis of ischemic stroke in humans
- Control of the microsporidian parasite Nosema ceranae in honey bees (Apis mellifera) using nutraceutical and immuno-stimulatory compounds
- Role of donor genotype in RT-QuIC seeding activity of chronic wasting disease prions using human and bank vole substrates
- Oral magnesium supplementation for leg cramps in pregnancy—An observational controlled trial
- Health care professionals’ knowledge of commonly used sedative, analgesic and neuromuscular drugs: A single center (Rambam Health Care Campus), prospective, observational survey
- Campylobacter portucalensis sp. nov., a new species of Campylobacter isolated from the preputial mucosa of bulls
- Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice
- Sleep quality and sex modify the relationships between trait energy and fatigue on state energy and fatigue
- The role of peer, parental, and school norms in predicting adolescents’ attitudes and behaviours of majority and different minority ethnic groups in Croatia
- Availability, prices and affordability of selected antibiotics and medicines against non-communicable diseases in western Cameroon and northeast DR Congo
- The effect of mutations derived from mouse-adapted H3N2 seasonal influenza A virus to pathogenicity and host adaptation
- Detection of posttraumatic pneumothorax using electrical impedance tomography—An observer-blinded study in pigs with blunt chest trauma
- Educators’ perceptions of organisational readiness for implementation of a pre-adolescent transdisciplinary school health intervention for inter-generational outcomes
- Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA
- The effects of sport expertise and shot results on basketball players’ action anticipation
- Framework and algorithms for identifying honest blocks in blockchain
- Exploring the impact of terminology differences in blood and organ donor decision making
- Platelet indices significantly correlate with liver fibrosis in HCV-infected patients
- The nitrate content of fresh and cooked vegetables and their health-related risks
- Bioreactor for mobilization of mesenchymal stem/stromal cells into scaffolds under mechanical stimulation: Preliminary results
- Non-gradient and genotype-dependent patterns of RSV gene expression
- Multiplex real-time PCR for the detection of Clavibacter michiganensis subsp. michiganensis, Pseudomonas syringae pv. tomato and pathogenic Xanthomonas species on tomato plants
- The 24-hour urinary cortisol in post-traumatic stress disorder: A meta-analysis
- Drug-eluting versus bare-metal stents for first myocardial infarction in patients with atrial fibrillation: A nationwide population-based cohort study
- Health-related quality of life among patients with type 2 diabetes mellitus in Eastern Province, Saudi Arabia: A cross-sectional study
- “I like the way I am, but I feel like I could get a little bit bigger”: Perceptions of body image among adolescents and youth living with HIV in Durban, South Africa
- Nanoparticle-based ‘turn-on’ scattering and post-sample fluorescence for ultrasensitive detection of water pollution in wider window
- Insights into the strategy of micro-environmental adaptation: Transcriptomic analysis of two alvinocaridid shrimps at a hydrothermal vent
- Thirty-day readmission after medical-surgical hospitalization for people who experience imprisonment in Ontario, Canada: A retrospective cohort study
- Hyper-spectral response and estimation model of soil degradation in Kenli County, the Yellow River Delta
- The association of telomere length and telomerase activity with adverse outcomes in older patients with non-ST-elevation acute coronary syndrome
- Construction of a high-density genetic map and fine mapping of a candidate gene locus for a novel branched-spike mutant in barley
- Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease
- Natural hybridization between Phyllagathis and Sporoxeia species produces a hybrid without reproductive organs
- The impact of peer attachment on prosocial behavior, emotional difficulties and conduct problems in adolescence: The mediating role of empathy
- Diagnostic performance of serum interferon gamma, matrix metalloproteinases, and periostin measurements for pulmonary tuberculosis in Japanese patients with pneumonia
- Characterization of black patina from the Tiber River embankments using Next-Generation Sequencing
- Problem gambling, associations with comorbid health conditions, substance use, and behavioural addictions: Opportunities for pathways to treatment
- Nanosheet wrapping-assisted coverslip-free imaging for looking deeper into a tissue at high resolution
- Validity of cerebrovascular ICD-9-CM codes in healthcare administrative databases. The Umbria Data-Value Project
- Torque teno virus viral load is related to age, CMV infection and HLA type but not to Alzheimer's disease
- Associations of cigarette smoking and burden of thoracic aortic calcification in asymptomatic individuals: A dose-response relationship
- Transforming assessment of speech in children with cleft palate via online crowdsourcing
- Human-raptor conflict in rural settlements of Colombia
- Assessment of peritoneal microbial features and tumor marker levels as potential diagnostic tools for ovarian cancer
- Deficiency syndromes in top predators associated with large-scale changes in the Baltic Sea ecosystem
- Perceived relative social status and cognitive load influence acceptance of unfair offers in the Ultimatum Game
- Hepatitis B and C virus infection among HIV patients within the public and private healthcare systems in Chile: A cross-sectional serosurvey
- Retraction: Oncogenic Fibulin-5 Promotes Nasopharyngeal Carcinoma Cell Metastasis through the FLJ10540/AKT Pathway and Correlates with Poor Prognosis
- From seed to flour: Sowing sustainability in the use of cantaloupe melon residue (Cucumis melo L. var. reticulatus)
- Core Scientific Dataset Model: A lightweight and portable model and file format for multi-dimensional scientific data
- Accounting for measurement error to assess the effect of air pollution on omic signals
- Leucine zipper transcription factor-like 1 binds adaptor protein complex-1 and 2 and participates in trafficking of transferrin receptor 1
- Barriers for tuberculosis case finding in Southwest Ethiopia: A qualitative study
- Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia
- A lower psoas muscle volume was associated with a higher rate of recurrence in male clear cell renal cell carcinoma
- Two angles of overqualification-the deviant behavior and creative performance: The role of career and survival job
- Cost-utility analysis of de-escalating biological disease-modifying anti-rheumatic drugs in patients with rheumatoid arthritis
- Efficient estimation of stereo thresholds: What slope should be assumed for the psychometric function?
- Learning efficient haptic shape exploration with a rigid tactile sensor array
- Effects of dietary supplementation with a microalga (Schizochytrium sp.) on the hemato-immunological, and intestinal histological parameters and gut microbiota of Nile tilapia in net cages
- Regional versus local wind speed and direction at a narrow beach with a high and steep foredune
- Fragmented QRS complex in patients with systemic lupus erythematosus at the time of diagnosis and its relationship with disease activity
- Severe thiamine deficiency in eastern Baltic cod (Gadus morhua)
- Transfer entropy as a variable selection methodology of cryptocurrencies in the framework of a high dimensional predictive model
- Psychometric validation of Czech version of the Sport Motivation Scale
- Correction: Multiple innate antibacterial immune defense elements are correlated in diverse ungulate species
- Recognition of personality disorder and anxiety disorder comorbidity in patients treated for depression in secondary psychiatric care
- Correction: Strategies for achieving high sequencing accuracy for low diversity samples and avoiding sample bleeding using illumina platform
- PLOS One
- Archív čísel
- Aktuálne číslo
- Informácie o časopise
Najčítanejšie v tomto čísle
- Psychometric validation of Czech version of the Sport Motivation Scale
- Comparison of Monocyte Distribution Width (MDW) and Procalcitonin for early recognition of sepsis
- Effects of supplemental creatine and guanidinoacetic acid on spatial memory and the brain of weaned Yucatan miniature pigs
- The Brief Measure of Emotional Preoperative Stress (B-MEPS) as a new predictive tool for postoperative pain: A prospective observational cohort study