#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#
preLekára.sk / Odborné časopisy / PLOS One / 2020 - 1

Antenatal depression and its association with adverse birth outcomes in low and middle-income countries: A systematic review and meta-analysis

English version

Autoři: Abel Fekadu Dadi aff001;  Emma R. Miller aff002;  Lillian Mwanri aff002
Působiště autorů: Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia aff001;  College of Medicine and Public Health, Flinders University, Health Sciences Building, Adelaide, South Australia aff002
Vyšlo v časopise: PLoS ONE 15(1)
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pone.0227323

Souhrn

Background

Depression in pregnancy (antenatal depression) in many low and middle-income countries is not well documented and has not been given priority for intervention due to competing urgencies and the belief that it does not immediately cause fatalities, which mainly emanated from lack of comprehensive research on the area. To fill this research gap, this systematic review was conducted to investigate the burden of antenatal depression and its consequences on birth outcomes in low -⁠ and middle-income countries.

Methods

We systematically searched the databases: CINHAL, MEDLINE, EMCare, PubMed, PSyc Info, Psychiatry online, and Scopus for studies conducted in low and middle-income countries about antenatal depression and its association with adverse birth outcomes. We have included observational studies (case control, cross-sectional and cohort studies), written in English-language, scored in the range of “good quality” on the Newcastle Ottawa Scale (NOS), and were published between January 1, 2007 and December 31, 2017. Studies were excluded if a standardized approach was not used to measure main outcomes, they were conducted on restricted (high risk) populations, or had fair to poor quality score on NOS. We used Higgins and Egger’s to test for heterogeneity and publication bias. Primary estimates were pooled using a random effect meta-analysis. The study protocol was registered in PROSPERO with protocol number CRD42017082624.

Result

We included 64 studies (with 44, 035 women) on antenatal depression and nine studies (with 5,540 women) on adverse birth outcomes. Antenatal depression was higher in the lower-income countries (Pooled Prevalence (PP) = 34.0%; 95%CI: 33.1%-34.9%) compared to the middle-income countries (PP = 22.7%, 95%CI: 20.1%-25.2%) and increased over the three trimesters. Pregnant women with a history of economic difficulties, poor marital relationships, common mental disorders, poor social support, bad obstetric history, and exposure to violence were more likely to report antenatal depression. The risk of having preterm birth (2.41; 1.47–3.56) and low birth weight (1.66; 1.06–2.61) was higher in depressed mothers compared to mothers without depression.

Conclusions

Antenatal depression was higher in low-income countries than in middle-income countries and was found to be a risk factor for low birth weight and preterm births. The economic, maternal, and psychosocial risk factors were responsible for the occurrence of antenatal depression. While there could be competing priority agenda to juggle for health policymakers in low-income countries, interventions for antenatal depression should be reprioritized as vitally important in order to prevent the poor maternal and perinatal outcomes identified in this review.

Klíčová slova:

Birth – Pregnancy – Birth weight – Systematic reviews – Depression – Medical risk factors – Preterm birth – Economic history

Zdroje

1. WHO. Depression and other common mental disorders: global health estimates. World Health Organization; 2017.

2. Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A, et al. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. 2016;388(10053):1459–544.

3. Vos T, Allen C, Arora M, Barber RM, Bhutta ZA, Brown A, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. 2016;388(10053):1545–602.

4. GBD. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The lancet. 2015(388):1459–544.

5. Sunday EM, Okoli PC, Dinwoke VO. Level of awareness and treatment of anxiety and depression during pregnancy in southeast Nigeria. S Afr J Psychiatr. 2018;24 : 1192. doi: 10.4102/sajpsychiatry.v24i0.1192 30473881

6. Mukherjee S, Trepka M, Pierre-Victor D, Bahelah R, Avent T. Racial/Ethnic Disparities in Antenatal Depression in the United States: A Systematic Review. Maternal & Child Health Journal. 2016;20(9):1780–97.

7. Chatillon O, Even C. [Antepartum depression: prevalence, diagnosis and treatment]. Encephale. 2010;36(6):443–51. doi: 10.1016/j.encep.2010.02.004 21130227

8. Mitchell-Jones N, Gallos I, Farren J, Tobias A, Bottomley C, Bourne T. Psychological morbidity associated with hyperemesis gravidarum: a systematic review and meta-analysis: BJOG: An International Journal of Obstetrics and Gynaecology. 124(1) (pp 20–30), 2017.

9. Biaggi A, Conroy S, Pawlby S, Pariante CM. Identifying the women at risk of antenatal anxiety and depression: A systematic review. Journal of Affective Disorders. 2016;191 : 62–77. doi: 10.1016/j.jad.2015.11.014 26650969

10. Gelaye B, Rondon MB, Araya R, Williams MA. Epidemiology of maternal depression, risk factors, and child outcomes in low-income and middle-income countries. The Lancet Psychiatry. 2016;3(10):973–82. doi: 10.1016/S2215-0366(16)30284-X 27650773

11. Woody CA, Ferrari AJ, Siskind DJ, Whiteford HA, Harris MG. A systematic review and meta-regression of the prevalence and incidence of perinatal depression. J Affect Disord. 2017;219 : 86–92. doi: 10.1016/j.jad.2017.05.003 28531848

12. Slomian J, Honvo G, Emonts P, Reginster J-Y, Bruyère O. Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes. Womens Health (Lond). 2019;15 : 1745506519844044.

13. Li J, Mao J, Du Y, Morris JL, Gong G, Xiong X. Health-related quality of life among pregnant women with and without depression in Hubei, China. Matern Child Health J. 2012;16(7):1355–63. doi: 10.1007/s10995-011-0900-z 22045020

14. Franke K, Bergh Bvd, de Rooij SR, Roseboom TJ, Nathanielsz PW, Witte OW, et al. Effects of Prenatal Stress on Structural Brain Development and Aging in Humans. bioRxiv. 2017 Jan 1 : 148916.

15. Sikander S, Ahmad I, Bates LM, Gallis J, Hagaman A, O'Donnell K, et al. Cohort Profile: Perinatal depression and child socioemotional development; the Bachpan cohort study from rural Pakistan. BMJ Open. 2019;9(5).

16. Wen DJ, Poh JS, Ni SN, Chong YS, Chen H, Kwek K, et al. Influences of prenatal and postnatal maternal depression on amygdala volume and microstructure in young children. Translational Psychiatry. 2017;7(4).

17. Latendresse G, Wong B, Dyer J, Wilson B, Baksh L, Hogue C. Duration of Maternal Stress and Depression. Nursing Research. 2015;64(5):331–41. doi: 10.1097/NNR.0000000000000117 26325275

18. Diego MA, Field T, Hernandez-Reif M, Schanberg S, Kuhn C, Gonzalez-Quintero VH. Prenatal depression restricts fetal growth. Early Human Development. 2009;85(1):65–70. doi: 10.1016/j.earlhumdev.2008.07.002 18723301

19. Field T, Diego M, Hernandez-rief M, Figueiredo B, Schanberg. Kuhn C, et al. Chronic prenatal depression and neonatal outcome. International Journal of Neuroscience. 2008;118(1):95–103. doi: 10.1080/00207450601042144 18041608

20. Stringer E, Johnson J, Jackson C, Meltzer-Brody S. 646: Antenatal depression in an urban population of pregnant adolescents and young adults may contribute to preterm birth. American Journal of Obstetrics & Gynecology. 2016;214(1):S344.

21. Kim DR, Sockol LE, Sammel MD, Kelly C, Moseley M, Epperson C. Elevated risk of adverse obstetric outcomes in pregnant women with depression. Archives of Women's Mental Health. 2013;16(6):475–82. doi: 10.1007/s00737-013-0371-x 23934018

22. Feinberg ME, Jones DE, Roettger ME, Hostetler ML, Sakuma KL, Paul IM, et al. Preventive Effects on Birth Outcomes: Buffering Impact of Maternal Stress, Depression, and Anxiety. Matern Child Health J. 2016;20(1):56–65. doi: 10.1007/s10995-015-1801-3 26194453

23. Raisanen S, Lehto SM, Nielsen HS, Gissler M, Kramer MR, Heinonen S. Risk factors for and perinatal outcomes of major depression during pregnancy: a population-based analysis during 2002–2010 in Finland. BMJ Open. 2014;4(11)

24. Quispel C, Bangma M, Kazemier BM, Steegers EAP, Hoogendijk WJG, Papatsonis DNM, et al. The role of depressive symptoms in the pathway of demographic and psychosocial risks to preterm birth and small for gestational age. Midwifery. 2014;30(8):919–25. doi: 10.1016/j.midw.2014.03.008 24742634

25. Szegda K, Bertone-Johnson ER, Pekow P, Powers S, Markenson G, Dole N, et al. Depression during pregnancy and adverse birth outcomes among predominantly puerto rican women. Maternal and child health journal. 2017 Apr 1;21(4):942–52. doi: 10.1007/s10995-016-2195-6 27995411

26. Chang HY, Keyes KM, Lee KS, Choi IA, Kim SJ, Kim KW, et al. Prenatal maternal depression is associated with low birth weight through shorter gestational age in term infants in Korea. Early Human Development. 2014;90(1):15–20. doi: 10.1016/j.earlhumdev.2013.11.006 24331828

27. Husain N, Munshi T, Jafri F, Husain M, Parveen A, Saeed Q, et al. Antenatal depression is not associated with low birth weight: A study from urban Pakistan. Frontiers in psychiatry. 2014 Dec 10;5 : 175. doi: 10.3389/fpsyt.2014.00175 25540627

28. Saeed A, Raana T, Saeed AM, Humayun A. Effect of antenatal depression on maternal dietary intake and neonatal outcome: a prospective cohort. Nutrition Journal. 2016;15(1):64. doi: 10.1186/s12937-016-0184-7 27401187

29. Stewart DE. Depression during Pregnancy. New England Journal of Medicine. 2011;365(17):1605–11. doi: 10.1056/NEJMcp1102730 22029982

30. Amiel Castro RT, Pinard Anderman C, Glover V, O’Connor TG, Ehlert U, Kammerer M. Associated symptoms of depression: patterns of change during pregnancy. Archives of Women's Mental Health. 2017;20(1):123–8. doi: 10.1007/s00737-016-0685-6 27878386

31. Araujo DM, Vilarim MM, Sabroza AR, Nardi AE. [Depression during pregnancy and low birth weight: a systematic literature review]. Cad Saude Publica. 2010;26(2):219–27. doi: 10.1590/s0102-311x2010000200002 20396838

32. Hanlon C, Medhin G, Alem A, Tesfaye F, Lakew Z, Worku B, et al. Impact of antenatal common mental disorders upon perinatal outcomes in Ethiopia: The P-MaMiE population-based cohort study. Tropical Medicine and International Health. 2009;14(2):156–66. doi: 10.1111/j.1365-3156.2008.02198.x 19187514

33. Gelaye B, Rondon M, Araya R, Williams MA. Epidemiology of maternal depression, risk factors, and child outcomes in low-income and middle-income countries. The lancet Psychiatry. 2016;3(10):973–82. doi: 10.1016/S2215-0366(16)30284-X 27650773

34. Bae J-M. A suggestion for quality assessment in systematic reviews of observational studies in nutritional epidemiology. Epidemiology and Health. 2016;38.

35. Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25(9):603–5. doi: 10.1007/s10654-010-9491-z 20652370

36. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA. 2000;283(15):2008–12. doi: 10.1001/jama.283.15.2008 10789670

37. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. Bmj. 1997;315(7109):629–34. doi: 10.1136/bmj.315.7109.629 9310563

38. Loannidis JP. Interpretation of tests of heterogeneity and bias in meta-analysis. Journal of evaluation in clinical practice. 2008;14(5):951–7. doi: 10.1111/j.1365-2753.2008.00986.x 19018930

39. Duval S, Tweedie R. Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics. 2000;56(2):455–63. doi: 10.1111/j.0006-341x.2000.00455.x 10877304

40. Galbraith RF. Graphical display of estimates having differing standard errors. Technometrics. 1988;30(3):271–81.

41. Higgins J, Thompson S, Deeks J, Altman D. Statistical heterogeneity in systematic reviews of clinical trials: a critical appraisal of guidelines and practice. Journal of health services research & policy. 2002;7(1):51–61.

42. Fletcher J. What is heterogeneity and is it important? BMJ: British Medical Journal. 2007;334(7584):94–6. doi: 10.1136/bmj.39057.406644.68 17218716

43. Stata A. Stata Base Reference Manual Release 14. 2015.

44. Adewuya AO, Ola BA, Aloba OO, Dada AO, Fasoto OO. Prevalence and correlates of depression in late pregnancy among Nigerian women. Depression & Anxiety. 2007;24(1):15–21.

45. Esimai O, Fatoye F, Quiah A, Vidal O, Momoh R. Antepartum anxiety and depressive symptoms: a study of Nigerian women during the three trimesters of pregnancy. J Obstet Gynaecol. 2008;28.

46. Gausia K, Fisher C, Ali M, Oosthuizen J. Antenatal depression and suicidal ideation among rural Bangladeshi women: a community-based study. Archives of Women's Mental Health. 2009;12(5):351–8. doi: 10.1007/s00737-009-0080-7 19468825

47. Luna Matos ML, Salinas Pielago J, Luna Figueroa A. [Major depression in pregnant women served by the National Materno-Perinatal Institute in Lima, Peru]. Pan American Journal of Public Health. 2009;26(4):310–4. doi: 10.1590/s1020-49892009001000004 20107678

48. Mitsuhiro SS, Chalem E, Moraes Barros MC, Guinsburg R, Laranjeira R. Brief report: Prevalence of psychiatric disorders in pregnant teenagers. Journal of Adolescence. 2009;32(3):747–52. doi: 10.1016/j.adolescence.2008.12.001 19349073

49. Pereira PK, Lovisi GM, Pilowsky DL, Lima LA, Legay LF. Depression during pregnancy: prevalence and risk factors among women attending a public health clinic in Rio de Janeiro, Brazil. Cadernos de Saude Publica. 2009;25(12):2725–36. doi: 10.1590/s0102-311x2009001200019 20191163

50. Pottinger AM, Trotman-Edwards H, Younger N. Detecting depression during pregnancy and associated lifestyle practices and concerns among women in a hospital-based obstetric clinic in Jamaica. General Hospital Psychiatry. 2009;31(3):254–61. doi: 10.1016/j.genhosppsych.2009.02.002 19410104

51. Golbasi Z, Kelleci M, Kisacik G, Cetin A. Prevalence and Correlates of Depression in Pregnancy Among Turkish Women. Maternal and Child Health Journal. 2010;14(4):485–91. doi: 10.1007/s10995-009-0459-0 19238527

52. Silva RA, Jansen K, Souza LD, Moraes IG, Tomasi E, Silva GD, et al. Depression during pregnancy in the Brazilian public health care system. Brazilian Journal of Psychiatry. 2010 Jun;32(2):139–44 doi: 10.1590/s1516-44462010000200008 20658053

53. Kaaya SF, Mbwambo JK, Kilonzo GP, Van Den Borne H, Leshabari MT, Fawzi MC, et al. Socio-economic and partner relationship factors associated with antenatal depressive morbidity among pregnant women in Dar es Salaam, Tanzania. Tanzania journal of health research. 2010;12(1):23–35. doi: 10.4314/thrb.v12i1.56276 20737826

54. Mohammad KI, Gamble J, Creedy DK. Prevalence and factors associated with the development of antenatal and postnatal depression among Jordanian women. Midwifery. 2011;27(6)

55. Nasreen HE, Kabir ZN, Forsell Y, Edhborg M. Prevalence and associated factors of depressive and anxiety symptoms during pregnancy: a population based study in rural Bangladesh. BMC Womens Health. 2011;11 : 22. doi: 10.1186/1472-6874-11-22 21635722

56. Lau Y, Yin L, Wang Y. Antenatal Depressive Symptomatology, Family Conflict and Social Support Among Chengdu Chinese Women. Maternal & Child Health Journal. 2011;15(8):1416–26.

57. Senturk V, Abas M, Berksun O, Stewart R. Social support and antenatal depression in extended and nuclear family environments in Turkey: a cross-sectional survey. BMC Psychiatry. 2011;11.

58. Faisal-Cury A, Savoia MG, Menezes PR. Coping style and depressive symptomatology during pregnancy in a private setting sample. The Spanish journal of psychology. 2012;15(1):295–305. doi: 10.5209/rev_sjop.2012.v15.n1.37336 22379719

59. Melo EF Jr, Cecatti JG, Pacagnella RC, Leite DFB, Vulcani DE, Makuch MY. The prevalence of perinatal depression and its associated factors in two different settings in Brazil. Journal of Affective Disorders. 2012;136(3):1204–8. doi: 10.1016/j.jad.2011.11.023 22169251

60. Hartley M, Tomlinson M, Greco E, Comulada WS, Stewart J, le Roux I, et al. Depressed mood in pregnancy: Prevalence and correlates in two Cape Town peri-urban settlements. Reproductive Health. 2011;8(1):9.

61. Rochat TJ, Tomlinson M, Barnighausen T, Newell ML, Stein A. The prevalence and clinical presentation of antenatal depression in rural South Africa. Journal of Affective Disorders. 2011;135(1–3):362–73. doi: 10.1016/j.jad.2011.08.011 21880372

62. Ajinkya S, Jadhav PR, Srivastava NN. Depression during pregnancy: Prevalence and obstetric risk factors among pregnant women attending a tertiary care hospital in Navi Mumbai. Industrial Psychiatry Journal. 2013;22(1):37–40. doi: 10.4103/0972-6748.123615 24459372

63. Fisher J, Tran T, Duc Tran T, Dwyer T, Nguyen T, Casey GJ, et al. Prevalence and risk factors for symptoms of common mental disorders in early and late pregnancy in Vietnamese women: A prospective population-based study. Journal of Affective Disorders. 2013;146(2):213–9. doi: 10.1016/j.jad.2012.09.007 23026129

64. Silva R, Jansen K, Souza L, Quevedo L, Barbosa L, Moraes I, et al. Sociodemographic risk factors of perinatal depression: a cohort study in the public health care system. Revista Brasileira de Psiquiatria. 2012;34(2):143–8. doi: 10.1590/s1516-44462012000200005 22729409

65. Lara MA, Natera-Rey G, Berenzon S, Juarez-Garcia F, Villatoro-Velazquez JA, Nieto L, et al. Intimate partner violence and depressive symptoms in pregnant Mexican women: national survey results. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion. 2014;66(5):431–8. 25695386

66. Manikkam L, Burns JK. Antenatal depression and its risk factors: an urban prevalence study in KwaZulu-Natal. S Afr Med J. 2012;102.

67. Fadzil A, Balakrishnan K, Razali R, Sidi H, Malapan T, Japaraj RP, et al. Risk factors for depression and anxiety among pregnant women in Hospital Tuanku Bainun, Ipoh, Malaysia: Asia-Pacific Psychiatry. 5 (pp 7–13), 2013. doi: 10.1111/appy.12036 23857831

68. Jeong H-G, Lim J-S, Lee M-S, Kim S-H, Jung I-K, Joe S-H. The association of psychosocial factors and obstetric history with depression in pregnant women: Focus on the role of emotional support. General Hospital Psychiatry. 2013;35(4):354–8. doi: 10.1016/j.genhosppsych.2013.02.009 23541804

69. Bindt C, Guo N, Bonle MT, Appiah-Poku J, Hinz R, Barthel D, et al. No association between antenatal common mental disorders in low-obstetric risk women and adverse birth outcomes in their offspring: results from the CDS study in Ghana and Cote D'Ivoire. PLoS One. 2013;8(11).

70. Dibaba Y, Fantahun M, Hindin MJ. The association of unwanted pregnancy and social support with depressive symptoms in pregnancy: evidence from rural Southwestern Ethiopia. BMC pregnancy and childbirth. 2013;13.

71. Assefa Gemta W. Prevalence and factors associated with antenatal depression among women following antenatal care at Shashemane health facilities, South Ethiopia. Annals of Global Health. 2015;81(1):90.

72. Guo N, Bindt C, Te Bonle M, Appiah-Poku J, Hinz R, Barthel D, et al. Association of antepartum and postpartum depression in Ghanaian and Ivorian women with febrile illness in their offspring: a prospective birth cohort study. Am J Epidemiol. 2013;178(9):1394–402. doi: 10.1093/aje/kwt142 24013202

73. Dmitrovic BK, Dugalić MG, Balkoski GN, Dmitrovic A, Soldatovic I. Frequency of perinatal depression in Serbia and associated risk factors. International Journal of Social Psychiatry. 2013;60(6):528–32. doi: 10.1177/0020764013511067 24300083

74. Abujilban SK, Abuidhail J, Al-Modallal H, Hamaideh S, Mosemli O. Predictors of Antenatal Depression Among Jordanian Pregnant Women in Their Third Trimester. Health Care for Women International. 2014;35(2):200–15. doi: 10.1080/07399332.2013.817411 24020729

75. Aktas S, Yesilcicek Calik K. Factors Affecting Depression During Pregnancy and the Correlation Between Social Support and Pregnancy Depression. Iranian Red Crescent Medical Journal. 2015;17(9).

76. Stewart RC, Umar E, Tomenson B, Creed F. A cross-sectional study of antenatal depression and associated factors in Malawi. Archives of Women's Mental Health. 2014;17(2):145–54. doi: 10.1007/s00737-013-0387-2 24240635

77. Weobong B, Soremekun S, Ten Asbroek AH, Amenga-Etego S, Danso S, Owusu-Agyei S, et al. Prevalence and determinants of antenatal depression among pregnant women in a predominantly rural population in Ghana: The DON population-based study. Journal of Affective Disorders. 2014;165 : 1–7. doi: 10.1016/j.jad.2014.04.009 24882170

78. Waqas A, Raza N, Lodhi HW, Muhammad Z, Jamal M, Rehman A. Psychosocial factors of antenatal anxiety and depression in Pakistan: is social support a mediator? PLoS ONE; 2015;10(1).

79. Barrios YV, Gelaye B, Zhong Q, Nicolaidis C, Rondon MB, Garcia PJ, et al. Association of childhood physical and sexual abuse with intimate partner violence, poor general health and depressive symptoms among pregnant women.[Erratum appears in PLoS One. 2015;10(3)

80. De Oliveira Fonseca-Machado M, Alves LC, dos Santos Monteiro JC, Stefanello J, Nakano AMS, Haas VJ, et al. Depressive disorder in pregnant Latin women: Does intimate partner violence matter? Journal of Clinical Nursing. 2015;24(9–10):1289–99. doi: 10.1111/jocn.12728 25581085

81. Abdelhai R, Mosleh H. Screening for antepartum anxiety and depression and their association with domestic violence among Egyptian pregnant women. Journal of the Egyptian Public Health Association. 2015;90(3):101–8. doi: 10.1097/01.EPX.0000471670.64665.8f 26544838

82. Mahenge B, Stockl H, Likindikoki S, Kaaya S, Mbwambo J. The prevalence of mental health morbidity and its associated factors among women attending a prenatal clinic in Tanzania. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. 2015;130(3):261–5.

83. Rwakarema M, Premji SS, Nyanza EC, Riziki P, Palacios-Derflingher L. Antenatal depression is associated with pregnancy-related anxiety, partner relations, and wealth in women in Northern Tanzania: a cross-sectional study. BMC Women's Health. 2015;15 : 68. doi: 10.1186/s12905-015-0225-y 26329331

84. Heyningen TV, Myer L, Onah M, Tomlinson M, Field S, Honikman S. Antenatal depression and adversity in urban South Africa. Journal of Affective Disorders. 2016;203 : 121–9. doi: 10.1016/j.jad.2016.05.052 27285725

85. Biratu A, Haile D. Prevalence of antenatal depression and associated factors among pregnant women in Addis Ababa, Ethiopia: a cross-sectional study. Reprod Health. 2015;12 : 99. doi: 10.1186/s12978-015-0092-x 26514827

86. Bavle AD, Chandahalli AS, Phatak AS, Rangaiah N, Kuthandahalli SM, Nagendra PN. Antenatal Depression in a Tertiary Care Hospital. Indian Journal of Psychological Medicine. 2016;38(1):31–5. doi: 10.4103/0253-7176.175101 27011399

87. George C, Lalitha AR, Antony A, Kumar AV, Jacob KS. Antenatal depression in coastal South India: Prevalence and risk factors in the community. International Journal of Social Psychiatry. 2016;62(2):141–7. doi: 10.1177/0020764015607919 26443716

88. Moshki M, Cheravi K. Relationships among depression during pregnancy, social support and health locus of control among Iranian pregnant women. International Journal of Social Psychiatry. 2016;62(2):148–55. doi: 10.1177/0020764015612119 26582784

89. Padmapriya N, Bernard JY, Liang S, Loy SL, Shen Z, Kwek K, et al. Association of physical activity and sedentary behavior with depression and anxiety symptoms during pregnancy in a multiethnic cohort of Asian women. Archives of Women's Mental Health. 2016;19(6):1119–28. doi: 10.1007/s00737-016-0664-y 27664104

90. Alvarado-Esquivel C, Sifuentes-Alvarez A, Salas-Martinez C. Unhappiness with the fetal gender is associated with depression in adult pregnant women attending prenatal care in a public hospital in Durango, Mexico. International Journal of Biomedical Science. 2016;12(1):36–41. 27127452

91. de Jesus Silva MM, Carvalho Leite EPR, Nogueira DA, Clapis MJ. Depression in pregnancy. Prevalence and associated factors. Investigacion & Educacion en Enfermeria. 2016;34(2):342–50.

92. de Moraes EV, Campos RN, Avelino MM. Depressive symptoms in pregnancy: The influence of social, psychological and obstetric aspects. Revista Brasileira de Ginecologia e Obstetricia. 2016;38(6):293–300. doi: 10.1055/s-0036-1585072 27399924

93. Målqvist M, Clarke K, Matsebula T, Bergman M, Tomlinson M. Screening for Antepartum Depression Through Community Health Outreach in Swaziland. Journal of Community Health. 2016;41(5):946–52. doi: 10.1007/s10900-016-0175-9 26942766

94. Thompson O, Ajayi I. Prevalence of Antenatal Depression and Associated Risk Factors among Pregnant Women Attending Antenatal Clinics in Abeokuta North Local Government Area, Nigeria. Depression Research and Treatment. 2016.

95. Ayele TA, Azale T, Alemu K, Abdissa Z, Mulat H, Fekadu A. Prevalence and Associated Factors of Antenatal Depression among Women Attending Antenatal Care Service at Gondar University Hospital, Northwest Ethiopia. PLOS ONE. 2016;11(5)

96. Bisetegn TA, Mihretie G, Muche T. Prevalence and predictors of depression among pregnant women in debretabor town, northwest Ethiopia. PLoS ONE. 2016;11(9).

97. Bitew T, Hanlon C, Kebede E, Medhin G, Fekadu A. Antenatal depressive symptoms and maternal health care utilisation: a population-based study of pregnant women in Ethiopia. BMC Pregnancy & Childbirth. 2016;16(1):301.

98. Gelaye B, Addae G, Neway B, Larrabure-Torrealva GT, Qiu C, Stoner L, et al. Poor sleep quality, antepartum depression and suicidal ideation among pregnant women. Journal of Affective Disorders. 2017;209 : 195–200. doi: 10.1016/j.jad.2016.11.020 27930912

99. Hu HQ, Zhang J, Zhao W, Tian T, Huang AQ, Wang LL. [The occurrence and determinants of anxiety and depression symptoms in women of six counties/ districts in China during pregnancy]. Chung-Hua Yu Fang i Hsueh Tsa Chih [Chinese Journal of Preventive Medicine]. 2017;51(1):47–52. doi: 10.3760/cma.j.issn.0253-9624.2017.01.010 28056270

100. Shidhaye P, Shidhaye R, Phalke V. Association of gender disadvantage factors and gender preference with antenatal depression in women: a cross-sectional study from rural Maharashtra. Social Psychiatry & Psychiatric Epidemiology. 2017;09 : 09.

101. Coll CD, da Silveira MF, Bassani DG, Netsi E, Wehrmeister FC, Barros FC, et al. Antenatal depressive symptoms among pregnant women: Evidence from a Southern Brazilian population-based cohort study. Journal of Affective Disorders. 2017;209 : 140–6. doi: 10.1016/j.jad.2016.11.031 27914247

102. Mossie TB, Sibhatu AK, Dargie A, Ayele AD. Prevalence of Antenatal Depressive Symptoms and Associated Factors among Pregnant Women in Maichew, North Ethiopia: An Institution Based Study. Ethiopian Journal of Health Sciences. 2017;27(1):59–66. doi: 10.4314/ejhs.v27i1.8 28458491

103. Sahile MA, Segni MT, Awoke T, Bekele D. Prevalence and predictors of antenatal depressive symptoms among women attending Adama Hospital Antenatal Clinic, Adama, Ethiopia. International Journal of Nursing and Midwifery. 2017;9(5):58–64.

104. Rahman A, Bunn J, Lovel H, Creed F. Association between antenatal depression and low birthweight in a developing country. Acta Psychiatrica Scandinavica. 2007;115(6):481–6. doi: 10.1111/j.1600-0447.2006.00950.x 17498160

105. Nasreen HE, Kabir ZN, Forsell Y, Edhborg M. Low birth weight in offspring of women with depressive and anxiety symptoms during pregnancy: Results from a population based study in Bangladesh. BMC Public Health. 2010;10.

106. Niemi M, Falkenberg T, Petzold M, Chuc NT, Patel V. Symptoms of antenatal common mental disorders, preterm birth and low birthweight: a prospective cohort study in a semi-rural district of Vietnam. Tropical Medicine & International Health. 2013;18(6):687–95.

107. Sanchez SE, Puente GC, Atencio G, Qiu C, Yanez D, Gelaye B, et al. Risk of spontaneous preterm birth in relation to maternal depressive, anxiety, and stress symptoms. Journal of Reproductive Medicine. 2013;58(1–2):25–33. 23447915

108. Rao D, Kumar S, Mohanraj R, Frey S, Manhart LE, L. Kaysen D. The impact of domestic violence and depressive symptoms on preterm birth in South India. Social Psychiatry and Psychiatric Epidemiology. 2016;51(2):225–32. doi: 10.1007/s00127-015-1167-2 26747253

109. Wado YD, Afework MF, Hindin MJ. Effects of maternal pregnancy intention, depressive symptoms and social support on risk of low birth weight: A prospective study from Southwestern Ethiopia. PLoS ONE. 2014;9(5).

110. Mathers C. The global burden of disease: 2004 update: World Health Organization; 2008.

111. Mathers CD, Loncar D. Projections of Global Mortality and Burden of Disease from 2002 to 2030. PLoS medicine. 2006;3(11):e442. doi: 10.1371/journal.pmed.0030442 17132052

112. Fisher J, Cabral de Mello M, Patel V, Rahman A, Tran T, Holton S, et al. Prevalence and determinants of common perinatal mental disorders in women in low -⁠ and lower-middle-income countries: a systematic review. Bulletin of the World Health Organization. 2012;90(2):139–49H.

113. Truijens SEM, Spek V, van Son MJM, Guid Oei S, Pop VJM. Different patterns of depressive symptoms during pregnancy. Archives of Women's Mental Health. 2017;20(4):539–46. doi: 10.1007/s00737-017-0738-5 28593361

114. Bergink V, Kooistra L, Lambregtse-van den Berg MP, Wijnen H, Bunevicius R, van Baar A, et al. Validation of the Edinburgh Depression Scale during pregnancy. Journal of Psychosomatic Research. 2011;70(4):385–9. doi: 10.1016/j.jpsychores.2010.07.008 21414460

115. Chorwe-Sungani G, Chipps J. A systematic review of screening instruments for depression for use in antenatal services in low resource settings. BMC Psychiatry. 2017;17(1).

116. Chou F-H, Kuo S-H, Wang R-H. A Longitudinal Study of Nausea and Vomiting, Fatigue and Perceived Stress in, and Social Support for, Pregnant Women Through the Three Trimesters. The Kaohsiung Journal of Medical Sciences.24(6):306–14. doi: 10.1016/S1607-551X(08)70157-8 18635416

117. Shyn SI, Hamilton SP. The genetics of major depression: Moving beyond the monoamine hypothesis. The Psychiatric clinics of North America. 2010;33(1):125–40. doi: 10.1016/j.psc.2009.10.004 20159343

118. Underwood L, Waldie K, D’Souza S, Peterson ER, Morton S. A review of longitudinal studies on antenatal and postnatal depression. Archives of Women's Mental Health. 2016;19(5):711–20. doi: 10.1007/s00737-016-0629-1 27085795

119. Roomruangwong C, Epperson CN. Perinatal depression in Asian women: Prevalence, associated factors, and cultural aspects. Asian Biomedicine. 2011;5(2):179–93.

120. Stuart-Parrigon K, Stuart S. Perinatal Depression: An Update and Overview. Current Psychiatry Reports. 2014;16(9):468. doi: 10.1007/s11920-014-0468-6 25034859

121. Sparling TM, Henschke N, Nesbitt RC, Gabrysch S. The role of diet and nutritional supplementation in perinatal depression: a systematic review. Maternal & Child Nutrition. 2017;13(1).

122. Rechenberg K, Humphries D. Nutritional interventions in depression and perinatal depression. The Yale journal of biology and medicine. 2013;86(2):127–37. 23766734

123. Kaplan BJ, Crawford SG, Field CJ, Simpson JS. Vitamins, minerals, and mood. Psychological bulletin. 2007;133(5):747–60. doi: 10.1037/0033-2909.133.5.747 17723028

124. Hart C, de Vet R, Moran P, Hatch SL, Dean K. A UK population-based study of the relationship between mental disorder and victimisation. Soc Psychiatry Psychiatr Epidemiol. 2012;47(10):1581–90. doi: 10.1007/s00127-011-0464-7 22202973

125. Teicher MH, Samson JA, Polcari A, McGreenery CE. Sticks, stones, and hurtful words: relative effects of various forms of childhood maltreatment. Am J Psychiatry. 2006;163(6):993–1000. doi: 10.1176/ajp.2006.163.6.993 16741199

126. Teicher MH, Samson JA. Annual Research Review: Enduring neurobiological effects of childhood abuse and neglect. Journal of child psychology and psychiatry, and allied disciplines. 2016;57(3):241–66. doi: 10.1111/jcpp.12507 26831814

127. World Helath Organization. Global and regional estimates of violence against women: prevalence and health effects of intimate partner violence and nonpartner sexual violence. 2013.

128. Accortt EE, Cheadle ACD, Dunkel Schetter C. Prenatal Depression and Adverse Birth Outcomes: An Updated Systematic Review. Maternal and Child Health Journal. 2015;19(6):1306–37. doi: 10.1007/s10995-014-1637-2 25452215

129. Szegda Kathleen, Markenson Glenn, Bertone-Johnson Elizabeth R., Chasan-Taber Lisa. Depression during pregnancy: a risk factor for adverse neonatal outcomes? A critical review of the literature. The Journal of Maternal-Fetal & Neonatal Medicine. 2014;27(9):960–7.

130. Grigoriadis S, VonderPorten EH, Mamisashvili L, Tomlinson G, Dennis CL, Koren G, et al. The impact of maternal depression during pregnancy on perinatal outcomes: A systematic review and meta-analysis. Journal of Clinical Psychiatry. 2013;74(4):e321–e41. doi: 10.4088/JCP.12r07968 23656857

131. Grote NK, Bridge JA, Gavin AR, Melville JL, Iyengar S, Katon WJ. A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction. Arch Gen Psychiatry. 2010;67.

132. Wadhwa PD, Glynn L, Hobel CJ, Garite TJ, Porto M, Chicz-DeMet A, et al. Behavioral perinatology: biobehavioral processes in human fetal development. Regulatory peptides. 2002;108(2–3):149–57. doi: 10.1016/s0167-0115(02)00102-7 12220739

133. Wadhwa PD, Entringer S, Buss C, Lu MC. The contribution of maternal stress to preterm birth: issues and considerations. Clin Perinatol. 2011;38(3):351–84. doi: 10.1016/j.clp.2011.06.007 21890014

134. Azale T, Fekadu A, Hanlon C. Treatment gap and help-seeking for postpartum depression in a rural African setting. BMC Psychiatry. 2016;16(1):196.

135. Neggers Y, Goldenberg R, Cliver S, Hauth J. The relationship between psychosocial profile, health practices, and pregnancy outcomes. Acta Obstet Gynecol Scand. 2006;85(3):277–85. doi: 10.1080/00016340600566121 16553174

136. Kelly RH, Russo J, Holt VL, Danielsen BH, Zatzick DF, Walker E, et al. Psychiatric and substance use disorders as risk factors for low birth weight and preterm delivery. Obstet Gynecol. 2002;100(2):297–304. doi: 10.1016/s0029-7844(02)02014-8 12151153

137. Borders AE, Grobman WA, Amsden LB, Holl JL. Chronic stress and low birth weight neonates in a low-income population of women. Obstet Gynecol. 2007;109(2 Pt 1):331–8. doi: 10.1097/01.AOG.0000250535.97920.b5 17267833

Článek ETAPOD: A forecast model for prediction of black pod disease outbreak in Nigeria
Článek Disparate effects of antibiotic-induced microbiome change and enhanced fitness in Daphnia magna
Článek Deliver on Your Own: Disrespectful Maternity Care in rural Kenya
Článek Number of days required to estimate physical activity constructs objectively measured in different age groups: Findings from three Brazilian (Pelotas) population-based birth cohorts
Článek Exploring the mechanism of olfactory recognition in the initial stage by modeling the emission spectrum of electron transfer
Článek Risk of complications among diabetics self-reporting oral health status in Canada: A population-based cohort study
Článek Practical considerations in the use of a porcine model (Sus scrofa domesticus) to assess prevention of postoperative peritubal adhesions
Článek Transcriptional Differences in Peanut (Arachis hypogaea L.) Seeds at the Freshly Harvested, After-ripening and Newly Germinated Seed Stages: Insights into the Regulatory Networks of Seed Dormancy Release and Germination
Článek Identifying maintenance hosts for infection with Dichelobacter nodosus in free-ranging wild ruminants in Switzerland: A prevalence study
Článek Model order reduction for left ventricular mechanics via congruency training
Článek Production, purification and evaluation of biodegradation potential of PHB depolymerase of Stenotrophomonas sp. RZS7
Článek The impact of a wireless audio system on communication in robotic-assisted laparoscopic surgery: A prospective controlled trial
Článek Seroprevalence of viral and vector-borne bacterial pathogens in domestic dogs (Canis familiaris) in northern Botswana
Článek Musical expertise generalizes to superior temporal scaling in a Morse code tapping task
Článek Cross-cultural adaptation and psychometric evaluation of the Yoruba version of Oswestry disability index
Článek Post-transcriptional regulation of Rad51c by miR-222 contributes cellular transformation
Článek Can scientists fill the science journalism void? Online public engagement with science stories authored by scientists
Článek Retention and predictors of attrition among patients who started antiretroviral therapy in Zimbabwe’s national antiretroviral therapy programme between 2012 and 2015
Článek Prognostics for pain in osteoarthritis: Do clinical measures predict pain after total joint replacement?
Článek Effects of Transcranial Direct Current Stimulation on GABA and Glx in Children: A pilot study
Článek Evaluation of rice wild relatives as a source of traits for adaptation to iron toxicity and enhanced grain quality
Článek Brief communication: Long-term absence of Langerhans cells alters the gene expression profile of keratinocytes and dendritic epidermal T cells
Článek APOBEC3B reporter myeloma cell lines identify DNA damage response pathways leading to APOBEC3B expression
Článek Morphological diversity within a core collection of subterranean clover (Trifolium subterraneum L.): Lessons in pasture adaptation from the wild
Článek Feasibility of real-time in vivo 89Zr-DFO-labeled CAR T-cell trafficking using PET imaging
Článek Repository-based plasmid design
Článek A new method of recording from the giant fiber of Drosophila melanogaster shows that the strength of its auditory inputs remains constant with age
Článek Aberrant cervical innate immunity predicts onset of dysbiosis and sexually transmitted infections in women of reproductive age
Článek Safe mobility, socioeconomic inequalities, and aging: A 12-year multilevel interrupted time-series analysis of road traffic death rates in a Latin American country
Článek THAP11F80L cobalamin disorder-associated mutation reveals normal and pathogenic THAP11 functions in gene expression and cell proliferation
Článek Lesion of striatal patches disrupts habitual behaviors and increases behavioral variability
Článek A clinical method for estimating the modulus of elasticity of the human cornea in vivo
Článek Patient perceived value of teleophthalmology in an urban, low income US population with diabetes
Článek Evidence in support of chromosomal sex influencing plasma based metabolome vs APOE genotype influencing brain metabolome profile in humanized APOE male and female mice
Článek Accelerated sparsity based reconstruction of compressively sensed multichannel EEG signals
Článek Microvesicles from Lactobacillus reuteri (DSM-17938) completely reproduce modulation of gut motility by bacteria in mice
Článek Dense carbon-nanotube coating scaffolds stimulate osteogenic differentiation of mesenchymal stem cells
Článek Gamma Knife radiosurgery for vestibular schwannomas: Evaluation of planning using the sphericity degree of the target volume
Článek Purification and molecular characterization of phospholipase, antigen 5 and hyaluronidases from the venom of the Asian hornet (Vespa velutina)
Článek Why are animal source foods rarely consumed by 6-23 months old children in rural communities of Northern Ethiopia? A qualitative study
Článek A study to better understand under-utilization of laboratory tests for antenatal care in Senegal
Článek Effectiveness of information technology–enabled ‘SMART Eating’ health promotion intervention: A cluster randomized controlled trial
Článek Cauda Equina Syndrome Core Outcome Set (CESCOS): An international patient and healthcare professional consensus for research studies
Článek A new species of Macrocypraea (Gastropoda, Cypraeidae) from Trindade Island, Brazil, including phenotypic differentiation from remaining congeneric species
Článek Long term conjugated linoleic acid supplementation modestly improved growth performance but induced testicular tissue apoptosis and reduced sperm quality in male rabbit
Článek A new approach to the temporal significance of house orientations in European Early Neolithic settlements
Článek Persistence of chikungunya ECSA genotype and local outbreak in an upper medium class neighborhood in Northeast Brazil
Článek In vivo elongation of thin filaments results in heart failure
Článek Disparity in depressive symptoms between heterosexual and sexual minority men in China: The role of social support
Článek Effect of classroom intervention on student food selection and plate waste: Evidence from a randomized control trial
Článek Mating strategy is determinant of adenovirus prevalence in European bats
Článek Preventing HIV and HSV-2 through knowledge and attitudes: A replication study of a multi-component community-based intervention in Zimbabwe
Článek Randomized clinical trial analyzing maintenance of peripheral venous catheters in an internal medicine unit: Heparin vs. saline
Článek Patient-related factors may influence nursing perception of sleep in the Intensive Care Unit
Článek A randomized trial of a behavioral intervention to decrease hospital length of stay by decreasing bedrest
Článek Color image segmentation using adaptive hierarchical-histogram thresholding
Článek The role of demographic history and selection in shaping genetic diversity of the Galápagos penguin (Spheniscus mendiculus)
Článek Attitudes towards animal study registries and their characteristics: An online survey of three cohorts of animal researchers
Článek Risk perception and behavioral change during epidemics: Comparing models of individual and collective learning
Článek Risk factors for third-generation cephalosporin resistant Enterobacteriaceae in gestational urine cultures: A retrospective cohort study based on centralized electronic health records
Článek Residential neighbourhood greenspace is associated with reduced risk of cardiovascular disease: A prospective cohort study
Článek Potential socioeconomic impacts from ocean acidification and climate change effects on Atlantic Canadian fisheries
Článek Prevention and control of cholera with household and community water, sanitation and hygiene (WASH) interventions: A scoping review of current international guidelines
Článek Female finches prefer courtship signals indicating male vigor and neuromuscular ability
Článek The effect of spatial position and age within an egg-clutch on embryonic development and key metabolic enzymes in two clownfish species, Amphiprion ocellaris and Amphiprion frenatus
Článek The impact of translated reminder letters and phone calls on mammography screening booking rates: Two randomised controlled trials
Článek Application of a genetic algorithm to the keyboard layout problem
Článek Design and evaluation of a laboratory-based wheelchair castor testing protocol using community data
Článek Relationship between diabetic macular edema and choroidal layer thickness
Článek Evaluation of the predictive ability of ultrasound-based assessment of breast cancer using BI-RADS natural language reporting against commercial transcriptome-based tests
Článek A Comprehensive Data Gathering Network Architecture in Large-Scale Visual Sensor Networks
Článek Recovery of health-related quality of life after burn injuries: An individual participant data meta-analysis
Článek Modeling aggressive market order placements with Hawkes factor models
Článek Role of ecology in shaping external nasal morphology in bats and implications for olfactory tracking
Článek High expression of olfactomedin-4 is correlated with chemoresistance and poor prognosis in pancreatic cancer
Článek Development and validation of a prognostic model predicting symptomatic hemorrhagic transformation in acute ischemic stroke at scale in the OHDSI network
Článek Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction
Článek Tofu intake is inversely associated with risk of breast cancer: A meta-analysis of observational studies
Článek Influence of light on the infection of Aureococcus anophagefferens CCMP 1984 by a “giant virus”
Článek Temporal ordering of input modulates connectivity formation in a developmental neuronal network model of the cortex
Článek Healthy lifestyle index and its association with hypertension among community adults in Sri Lanka: A cross-sectional study
Článek From organ to cell: Multi-level telomere length assessment in patients with idiopathic pulmonary fibrosis
Článek How do critical care staff respond to organisational challenge? A qualitative exploration into personality types and cognitive processing in critical care
Článek Effects of supplemental creatine and guanidinoacetic acid on spatial memory and the brain of weaned Yucatan miniature pigs
Článek Community-Based Health Planning and Services Plus programme in Ghana: A qualitative study with stakeholders in two Systems Learning Districts on improving the implementation of primary health care
Článek An investigation of transportation practices in an Ontario swine system using descriptive network analysis
Článek Comparison of gridded precipitation datasets for rainfall-runoff and inundation modeling in the Mekong River Basin
Článek Functional interactions in patients with hemianopia: A graph theory-based connectivity study of resting fMRI signal
Článek The effects of dual-task cognitive interference on gait and turning in Huntington’s disease
Článek Novel imaging biomarkers for mapping the impact of mild mitochondrial uncoupling in the outer retina in vivo
Článek Hyperkalemia treatment modalities: A descriptive observational study focused on medication and healthcare resource utilization
Článek Long term impact of PositiveLinks: Clinic-deployed mobile technology to improve engagement with HIV care
Článek Comparison of post-transplantation diabetes mellitus incidence and risk factors between kidney and liver transplantation patients
Článek A definition-by-example approach and visual language for activity patterns in engineering disciplines
Článek A network analysis revealed the essential and common downstream proteins related to inguinal hernia
Článek Use of conventional cardiac troponin assay for diagnosis of non-ST-elevation myocardial infarction: ‘The Ottawa Troponin Pathway’
Článek Identification and characterization of miRNAs involved in cold acclimation of zebrafish ZF4 cells
Článek Research on motion planning for an indoor spray arm based on an improved potential field method
Článek Detailed analysis of the transverse arch of hallux valgus feet with and without pain using weightbearing ultrasound imaging and precise force sensors
Článek Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling
Článek Apolipoprotein-AI mimetic peptides D-4F and L-5F decrease hepatic inflammation and increase insulin sensitivity in C57BL/6 mice
Článek Treating patients with driving phobia by virtual reality exposure therapy – a pilot study
Článek Efficient processing of raster and vector data
Článek Therapeutic hypothermia after out of hospital cardiac arrest improve 1-year survival rate for selective patients
Článek Carotid plaques and neurological impairment in patients with acute cerebral infarction
Článek Deep learning based image reconstruction algorithm for limited-angle translational computed tomography
Článek Association between coffee drinking and telomere length in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
Článek Hyperbaric oxygen preconditioning and the role of NADPH oxidase inhibition in postischemic acute kidney injury induced in spontaneously hypertensive rats
Článek Rad51 paralogs and the risk of unselected breast cancer: A case-control study
Článek Diagnostic differences in respiratory breathing patterns and work of breathing indices in children with Duchenne muscular dystrophy
Článek The role of narrative in collaborative reasoning and intelligence analysis: A case study
Článek Proportions of CD4 test results indicating advanced HIV disease remain consistently high at primary health care facilities across four high HIV burden countries
Článek Modelling of amino acid turnover in the horse during training and racing: A basis for developing a novel supplementation strategy
Článek Single-modal and multi-modal false arrhythmia alarm reduction using attention-based convolutional and recurrent neural networks
Článek Eye-gaze information input based on pupillary response to visual stimulus with luminance modulation
Článek Trends of litter decomposition and soil organic matter stocks across forested swamp environments of the southeastern US
Článek Post mortem evaluation of inflammation, oxidative stress, and PPARγ activation in a nonhuman primate model of cardiac sympathetic neurodegeneration
Článek Were ancient foxes far more carnivorous than recent ones?—Carnassial morphological evidence
Článek Disruption in daily eating-fasting and activity-rest cycles in Indian adolescents attending school
Článek Plasma proteome profiling of freshwater and seawater life stages of rainbow trout (Oncorhynchus mykiss)
Článek Percent amplitude of fluctuation: A simple measure for resting-state fMRI signal at single voxel level
Článek Antimicrobial activity of Asteraceae species against bacterial pathogens isolated from postmenopausal women
Článek Are changes in depressive symptoms, general health and residential area socio-economic status associated with trajectories of waist circumference and body mass index?
Článek Extracellular vesicles of U937 macrophage cell line infected with DENV-2 induce activation in endothelial cells EA.hy926
Článek Link-centric analysis of variation by demographics in mobile phone communication patterns
Článek Tobacco smoking and health-related quality of life among university students: Mediating effect of depression
Článek The Shapley value for a fair division of group discounts for coordinating cooling loads
Článek Incidence of hospital-acquired pressure ulcers in patients with "minimal risk" according to the "Norton-MI" scale
Článek Lipoprotein(a) plasma levels are not associated with survival after acute coronary syndromes: An observational cohort study
Článek Use of Nanotrap particles for the capture and enrichment of Zika, chikungunya and dengue viruses in urine
Článek Pancreatic secretory trypsin inhibitor reduces multi-organ injury caused by gut ischemia/reperfusion in mice
Článek Biochemical characterization of Ty1 retrotransposon protease
Článek Lateral pressure equalisation as a principle for designing support surfaces to prevent deep tissue pressure ulcers
Článek The validation of the Beijing version of the Montreal Cognitive Assessment in Chinese patients undergoing hemodialysis
Článek Inflammasome expression is higher in ovarian tumors than in normal ovary
Článek HCV genotype profile in Brazil of mono-infected and HIV co-infected individuals: A survey representative of an entire country
Článek Engaging with change: Information and communication technology professionals’ perspectives on change at the mid-point in the UK/EU Brexit process
Článek Adherence to iron-folic acid supplement and associated factors among antenatal care attending pregnant mothers in governmental health institutions of Adwa town, Tigray, Ethiopia: Cross-sectional study
Článek Flower, seed, and fruit development in three Tunisian species of Polygonum: Implications for their taxonomy and evolution of distyly in Polygonaceae
Článek Development of a risk score for prediction of poor treatment outcomes among patients with multidrug-resistant tuberculosis
Článek Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virus
Článek Aqueous extract from Mangifera indica Linn. (Anacardiaceae) leaves exerts long-term hypoglycemic effect, increases insulin sensitivity and plasma insulin levels on diabetic Wistar rats
Článek Discovery of Jogalong virus, a novel hepacivirus identified in a Culex annulirostris (Skuse) mosquito from the Kimberley region of Western Australia
Článek Clinical, cytogenetic and molecular genetic characterization of a tandem fusion translocation in a male Holstein cattle with congenital hypospadias and a ventricular septal defect
Článek Detection of Torque Teno Virus (TTV) and TTV-Like Minivirus in patients with presumed infectious endophthalmitis in India
Článek CD4 rate of increase is preferred to CD4 threshold for predicting outcomes among virologically suppressed HIV-infected adults on antiretroviral therapy
Článek Estimating the basic reproduction number of a pathogen in a single host when only a single founder successfully infects
Článek What drugs modify the risk of iatrogenic impulse-control disorders in Parkinson’s disease? A preliminary pharmacoepidemiologic study
Článek Evaluating emotional distress and health-related quality of life in patients with heart failure and their family caregivers: Testing dyadic dynamics using the Actor-Partner Interdependence Model
Článek Community- and trophic-level responses of soil nematodes to removal of a non-native tree at different stages of invasion
Článek Association of ECG parameters with late gadolinium enhancement and outcome in patients with clinical suspicion of acute or subacute myocarditis referred for CMR imaging
Článek Catchment-scale export of antibiotic resistance genes and bacteria from an agricultural watershed in central Iowa
Článek Impact of multi-drug resistant bacteria on economic and clinical outcomes of healthcare-associated infections in adults: Systematic review and meta-analysis
Článek Characterization of a universal screening approach for congenital CMV infection based on a highly-sensitive, quantitative, multiplex real-time PCR assay
Článek Proof-of-concept for a non-invasive, portable, and wireless device for cardiovascular monitoring in pediatric patients
Článek On PTV definition for glioblastoma based on fiber tracking of diffusion tensor imaging data
Článek Genes associated with body weight gain and feed intake identified by meta-analysis of the mesenteric fat from crossbred beef steers
Článek Intraoperative computed tomography imaging for dose calculation in intraoperative electron radiation therapy: Initial clinical observations
Článek Human lung epithelial BEAS-2B cells exhibit characteristics of mesenchymal stem cells
Článek Simple non-mydriatic retinal photography is feasible and demonstrates retinal microvascular dilation in Chronic Obstructive Pulmonary Disease (COPD)
Článek Evaluation of a bioengineered ACL matrix’s osteointegration with BMP-2 supplementation
Článek Psychosocial profiles of physical activity fluctuation in office employees: A latent profile analysis
Článek Prevalence and characteristics of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) isolated from chicken meat in the province of Quebec, Canada
Článek Soluble AXL as a marker of disease progression and survival in melanoma
Článek Using machine learning methods to determine a typology of patients with HIV-HCV infection to be treated with antivirals
Článek Gender differences influence over insomnia in Korean population: A cross-sectional study
Článek Impact of scion/rootstock reciprocal effects on metabolomics of fruit juice and phloem sap in grafted Citrus reticulata
Článek Adapting cognitive diagnosis computerized adaptive testing item selection rules to traditional item response theory
Článek Autumn shifts in cold tolerance metabolites in overwintering adult mountain pine beetles
Článek Umbilical cord separation time, predictors and healing complications in newborns with dry care
Článek Analysis of attitudinal components towards statistics among students from different academic degrees
Článek Effects of fatigue induced by repeated-sprint on kicking accuracy and velocity in female soccer players
Článek A pre-clinical validation plan to evaluate analytical sensitivities of molecular diagnostics such as BD MAX MDR-TB, Xpert MTB/Rif Ultra and FluoroType MTB
Článek Leadership for success in transforming medical abortion policy in Canada
Článek Clinical correlates associated with the long-term response of bipolar disorder patients to lithium, valproate or lamotrigine: A retrospective study
Článek Forecasting stock prices with long-short term memory neural network based on attention mechanism
Článek On the genus Crossaster (Echinodermata: Asteroidea) and its distribution
Článek Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds
Článek An integrated vitamin E-coated polymer hybrid nanoplatform: A lucrative option for an enhanced in vitro macrophage retention for an anti-hepatitis B therapeutic prospect
Článek The effect of strontium and silicon substituted hydroxyapatite electrochemical coatings on bone ingrowth and osseointegration of selective laser sintered porous metal implants
Článek Molecular prevalence of Bartonella, Babesia, and hemotropic Mycoplasma species in dogs with hemangiosarcoma from across the United States
Článek Color discrimination and gas chromatography-mass spectrometry fingerprint based on chemometrics analysis for the quality evaluation of Schizonepetae Spica
Článek Comparisons of recurrence-free survival and overall survival between microwave versus radiofrequency ablation treatment for hepatocellular carcinoma: A multiple centers retrospective cohort study with propensity score matching
Článek Oral misoprostol, low dose vaginal misoprostol, and vaginal dinoprostone for labor induction: Randomized controlled trial
Článek The association between dietary patterns before and in early pregnancy and the risk of gestational diabetes mellitus (GDM): Data from the Malaysian SECOST cohort
Článek Dynamic Extreme Aneuploidy (DEA) in the vegetable pathogen Phytophthora capsici and the potential for rapid asexual evolution
Článek Assertive, trainable and older dogs are perceived as more dominant in multi-dog households
Článek Prediction of Uropathogens by Flow Cytometry and Dip-stick Test Results of Urine Through Multivariable Logistic Regression Analysis
Článek Interleukin 6 is increased in preclinical HNSCC models of acquired cetuximab resistance, but is not required for maintenance of resistance
Článek Impact of viral disease hypophagia on pig jejunal function and integrity
Článek Molecular evidence for horizontal transmission of chelonid alphaherpesvirus 5 at green turtle (Chelonia mydas) foraging grounds in Queensland, Australia
Článek Evaluation and validation of 2D biomechanical models of the knee for radiograph-based preoperative planning in total knee arthroplasty
Článek Soil-Transmitted Helminth infections reduction in Bhutan: A report of 29 years of deworming
Článek cagA gene EPIYA motif genetic characterization from Colombian Helicobacter pylori isolates: Standardization of a molecular test for rapid clinical laboratory detection
Článek Fast quantitative time lapse displacement imaging of endothelial cell invasion
Článek Two novel mutations in MSX1 causing oligodontia
Článek Dome-shaped macula in children and adolescents
Článek Targeted transcriptomic study of the implication of central metabolic pathways in mannosylerythritol lipids biosynthesis in Pseudozyma antarctica T-34
Článek Preliminary evidences of the presence of extracellular DNA single stranded forms in soil
Článek A comparison of quality of life between patients treated with different dialysis modalities in Taiwan
Článek Comparison of Monocyte Distribution Width (MDW) and Procalcitonin for early recognition of sepsis
Článek Morphological association between the muscles and bones in the craniofacial region
Článek Transcriptome analysis of Actinidia chinensis in response to Botryosphaeria dothidea infection
Článek Comparative study on skin protection activity of polyphenol-rich extract and polysaccharide-rich extract from Sargassum vachellianum
Článek Real-world data about emotional stress, disability and need for social care in a German IBD patient cohort
Článek The regenerative compatibility: A synergy between healthy ecosystems, environmental attitudes, and restorative experiences
Článek Perceptions of risk and influences of choice in pregnant women with obesity. An evidence synthesis of qualitative research
Článek The role of refugee and migrant migration status on medication adherence: Mediation through illness perceptions
Článek Sexual risk classes among youth experiencing homelessness: Relation to childhood adversities, current mental symptoms, substance use, and HIV testing
Článek Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells
Článek Novel broad-spectrum activity-based probes to profile malarial cysteine proteases
Článek Association between opioid analgesic therapy and initiation of buprenorphine management: An analysis of prescription drug monitoring program data
Článek Effect of a community-based approach of iron and folic acid supplementation on compliance by pregnant women in Kiambu County, Kenya: A quasi-experimental study
Článek Improvement project in higher education institutions: A BPEP-based model
Článek An updated evaluation of serum sHER2, CA15.3, and CEA levels as biomarkers for the response of patients with metastatic breast cancer to trastuzumab-based therapies
Článek Genome-wide association study of metabolic syndrome in Korean populations
Článek Drug therapy problems and treatment satisfaction among ambulatory patients with epilepsy in a specialized hospital in Ethiopia
Článek Plasma kynurenines and prognosis in patients with heart failure
Článek Occurrence and distribution of anthropogenic persistent organic pollutants in coastal sediments and mud shrimps from the wetland of central Taiwan
Článek Intensified visual clutter induces increased sympathetic signalling, poorer postural control, and faster torsional eye movements during visual rotation
Článek Gut microbiota composition alterations are associated with the onset of diabetes in kidney transplant recipients
Článek Shock index and TIMI risk index as valuable prognostic tools in patients with acute coronary syndrome complicated by cardiogenic shock
Článek Merit overrules theory of mind when young children share resources with others
Článek Metabolic analysis of amino acids and vitamin B6 pathways in lymphoma survivors with cancer related chronic fatigue
Článek Immunopathogenesis of canine chronic ulcerative stomatitis
Článek Generalizing findings from a randomized controlled trial to a real-world study of the iLookOut, an online education program to improve early childhood care and education providers’ knowledge and attitudes about reporting child maltreatment
Článek When and what to test for: A cost-effectiveness analysis of febrile illness test-and-treat strategies in the era of responsible antibiotic use
Článek Comparison of effects and safety in providing controlled hypotension during surgery between dexmedetomidine and magnesium sulphate: A meta-analysis of randomized controlled trials
Článek The gene encoding the ketogenic enzyme HMGCS2 displays a unique expression during gonad development in mice
Článek Efficacy of a mitochondrion-targeting agent for reducing the level of urinary protein in rats with puromycin aminonucleoside-induced minimal-change nephrotic syndrome
Článek Association of endothelial nitric oxide synthase (NOS3) gene polymorphisms with primary open-angle glaucoma in a Saudi cohort
Článek Antitrust analysis with upward pricing pressure and cost efficiencies
Článek Natural selection contributes to food web stability
Článek Pyramiding QTLs controlling tolerance against drought, salinity, and submergence in rice through marker assisted breeding
Článek Diversity and plant growth-promoting functions of diazotrophic/N-scavenging bacteria isolated from the soils and rhizospheres of two species of Solanum
Článek Sofosbuvir-based regimen for genotype 2 HCV infected patients in Taiwan: A real world experience
Článek The virulence domain of Shigella IcsA contains a subregion with specific host cell adhesion function
Článek Sequencing artifacts derived from a library preparation method using enzymatic fragmentation
Článek Quantitative analysis of adsorption and desorption of volatile organic compounds on reusable zeolite filters using gas chromatography
Článek Quo vadis Pantanal? Expected precipitation extremes and drought dynamics from changing sea surface temperature
Článek Cloud-computing and machine learning in support of country-level land cover and ecosystem extent mapping in Liberia and Gabon
Článek The Brief Measure of Emotional Preoperative Stress (B-MEPS) as a new predictive tool for postoperative pain: A prospective observational cohort study
Článek The impact of diabetes mellitus medication on the incidence of endogenous endophthalmitis
Článek Correction: Chl1 DNA helicase and Scc2 function in chromosome condensation through cohesin deposition
Článek Clinical and pathological features of thrombotic microangiopathy influencing long-term kidney transplant outcomes
Článek Occupational exposure to particulate matter from air pollution in the outdoor workplaces in Almaty during the cold season
Článek Morphological adjustment in free-living Steinernema feltiae infective juveniles to increasing concentration of Nemafric-BL phytonematicide
Článek Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis
Článek Concurrent lipidomics and proteomics on malignant plasma cells from multiple myeloma patients: Probing the lipid metabolome
Článek Retraction: SDR9C7 Promotes Lymph Node Metastases in Patients with Esophageal Squamous Cell Carcinoma
Článek Association between tuberculosis and depression on negative outcomes of tuberculosis treatment: A systematic review and meta-analysis
Článek Bioluminescent imaging of Arabidopsis thaliana using an enhanced Nano-lantern luminescence reporter system
Článek Biosynthetic pathway of indole-3-acetic acid in ectomycorrhizal fungi collected from northern Thailand
Článek Sex-specific and opposite modulatory aspects revealed by PPI network and pathway analysis of ischemic stroke in humans
Článek Control of the microsporidian parasite Nosema ceranae in honey bees (Apis mellifera) using nutraceutical and immuno-stimulatory compounds
Článek Role of donor genotype in RT-QuIC seeding activity of chronic wasting disease prions using human and bank vole substrates
Článek Oral magnesium supplementation for leg cramps in pregnancy—An observational controlled trial
Článek Health care professionals’ knowledge of commonly used sedative, analgesic and neuromuscular drugs: A single center (Rambam Health Care Campus), prospective, observational survey
Článek Campylobacter portucalensis sp. nov., a new species of Campylobacter isolated from the preputial mucosa of bulls
Článek Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice
Článek Sleep quality and sex modify the relationships between trait energy and fatigue on state energy and fatigue
Článek The role of peer, parental, and school norms in predicting adolescents’ attitudes and behaviours of majority and different minority ethnic groups in Croatia
Článek Availability, prices and affordability of selected antibiotics and medicines against non-communicable diseases in western Cameroon and northeast DR Congo
Článek The effect of mutations derived from mouse-adapted H3N2 seasonal influenza A virus to pathogenicity and host adaptation
Článek Detection of posttraumatic pneumothorax using electrical impedance tomography—An observer-blinded study in pigs with blunt chest trauma
Článek Educators’ perceptions of organisational readiness for implementation of a pre-adolescent transdisciplinary school health intervention for inter-generational outcomes
Článek Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA
Článek The effects of sport expertise and shot results on basketball players’ action anticipation
Článek Framework and algorithms for identifying honest blocks in blockchain
Článek Exploring the impact of terminology differences in blood and organ donor decision making
Článek Platelet indices significantly correlate with liver fibrosis in HCV-infected patients
Článek The nitrate content of fresh and cooked vegetables and their health-related risks
Článek Bioreactor for mobilization of mesenchymal stem/stromal cells into scaffolds under mechanical stimulation: Preliminary results
Článek Non-gradient and genotype-dependent patterns of RSV gene expression
Článek Multiplex real-time PCR for the detection of Clavibacter michiganensis subsp. michiganensis, Pseudomonas syringae pv. tomato and pathogenic Xanthomonas species on tomato plants
Článek The 24-hour urinary cortisol in post-traumatic stress disorder: A meta-analysis
Článek Health-related quality of life among patients with type 2 diabetes mellitus in Eastern Province, Saudi Arabia: A cross-sectional study
Článek “I like the way I am, but I feel like I could get a little bit bigger”: Perceptions of body image among adolescents and youth living with HIV in Durban, South Africa
Článek Nanoparticle-based ‘turn-on’ scattering and post-sample fluorescence for ultrasensitive detection of water pollution in wider window
Článek Insights into the strategy of micro-environmental adaptation: Transcriptomic analysis of two alvinocaridid shrimps at a hydrothermal vent
Článek Thirty-day readmission after medical-surgical hospitalization for people who experience imprisonment in Ontario, Canada: A retrospective cohort study
Článek Hyper-spectral response and estimation model of soil degradation in Kenli County, the Yellow River Delta
Článek The association of telomere length and telomerase activity with adverse outcomes in older patients with non-ST-elevation acute coronary syndrome
Článek Construction of a high-density genetic map and fine mapping of a candidate gene locus for a novel branched-spike mutant in barley
Článek Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease
Článek Natural hybridization between Phyllagathis and Sporoxeia species produces a hybrid without reproductive organs
Článek The impact of peer attachment on prosocial behavior, emotional difficulties and conduct problems in adolescence: The mediating role of empathy
Článek Diagnostic performance of serum interferon gamma, matrix metalloproteinases, and periostin measurements for pulmonary tuberculosis in Japanese patients with pneumonia
Článek Characterization of black patina from the Tiber River embankments using Next-Generation Sequencing
Článek Problem gambling, associations with comorbid health conditions, substance use, and behavioural addictions: Opportunities for pathways to treatment
Článek Nanosheet wrapping-assisted coverslip-free imaging for looking deeper into a tissue at high resolution
Článek Validity of cerebrovascular ICD-9-CM codes in healthcare administrative databases. The Umbria Data-Value Project
Článek Torque teno virus viral load is related to age, CMV infection and HLA type but not to Alzheimer's disease
Článek Associations of cigarette smoking and burden of thoracic aortic calcification in asymptomatic individuals: A dose-response relationship
Článek Transforming assessment of speech in children with cleft palate via online crowdsourcing
Článek Human-raptor conflict in rural settlements of Colombia
Článek Assessment of peritoneal microbial features and tumor marker levels as potential diagnostic tools for ovarian cancer
Článek Deficiency syndromes in top predators associated with large-scale changes in the Baltic Sea ecosystem
Článek Perceived relative social status and cognitive load influence acceptance of unfair offers in the Ultimatum Game
Článek Hepatitis B and C virus infection among HIV patients within the public and private healthcare systems in Chile: A cross-sectional serosurvey
Článek Retraction: Oncogenic Fibulin-5 Promotes Nasopharyngeal Carcinoma Cell Metastasis through the FLJ10540/AKT Pathway and Correlates with Poor Prognosis
Článek From seed to flour: Sowing sustainability in the use of cantaloupe melon residue (Cucumis melo L. var. reticulatus)
Článek Core Scientific Dataset Model: A lightweight and portable model and file format for multi-dimensional scientific data
Článek Accounting for measurement error to assess the effect of air pollution on omic signals
Článek Leucine zipper transcription factor-like 1 binds adaptor protein complex-1 and 2 and participates in trafficking of transferrin receptor 1
Článek Barriers for tuberculosis case finding in Southwest Ethiopia: A qualitative study
Článek Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia
Článek A lower psoas muscle volume was associated with a higher rate of recurrence in male clear cell renal cell carcinoma
Článek Two angles of overqualification-the deviant behavior and creative performance: The role of career and survival job
Článek Cost-utility analysis of de-escalating biological disease-modifying anti-rheumatic drugs in patients with rheumatoid arthritis
Článek Efficient estimation of stereo thresholds: What slope should be assumed for the psychometric function?
Článek Learning efficient haptic shape exploration with a rigid tactile sensor array
Článek Effects of dietary supplementation with a microalga (Schizochytrium sp.) on the hemato-immunological, and intestinal histological parameters and gut microbiota of Nile tilapia in net cages
Článek Regional versus local wind speed and direction at a narrow beach with a high and steep foredune
Článek Fragmented QRS complex in patients with systemic lupus erythematosus at the time of diagnosis and its relationship with disease activity
Článek Severe thiamine deficiency in eastern Baltic cod (Gadus morhua)
Článek Transfer entropy as a variable selection methodology of cryptocurrencies in the framework of a high dimensional predictive model
Článek Psychometric validation of Czech version of the Sport Motivation Scale
Článek Correction: Multiple innate antibacterial immune defense elements are correlated in diverse ungulate species
Článek Recognition of personality disorder and anxiety disorder comorbidity in patients treated for depression in secondary psychiatric care
Článek Correction: Strategies for achieving high sequencing accuracy for low diversity samples and avoiding sample bleeding using illumina platform
Článek Physicians’ perspectives regarding non-medical switching of prescription medications: Results of an internet e-survey
Článek Effects of Allium hookeri on gut microbiome related to growth performance in young broiler chickens
Článek Maternal depressive symptoms and children’s cognitive development: Does early childcare and child’s sex matter?
Článek Spectral characteristics of urine from patients with end-stage kidney disease analyzed using Raman Chemometric Urinalysis (Rametrix)
Článek Drug-eluting versus bare-metal stents for first myocardial infarction in patients with atrial fibrillation: A nationwide population-based cohort study
Článok vyšiel v časopise

PLOS One

2020 Číslo 1
Najčítanejšie tento týždeň
Najčítanejšie v tomto čísle
Kurzy

Zvýšte si kvalifikáciu online z pohodlia domova

nový kurz
Autori: doc. MUDr. David Zemánek, Ph.D., MUDr. Anna Chaloupka, Ph.D.
Všetky kurzy
Prihlásenie
Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.

Prihlásenie

Nemáte účet?  Registrujte sa

#ADS_BOTTOM_SCRIPTS#