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Prevention and control of cholera with household and community water, sanitation and hygiene (WASH) interventions: A scoping review of current international guidelines
Autoři: Lauren D’Mello-Guyett aff001; Karin Gallandat aff001; Rafael Van den Bergh aff003; Dawn Taylor aff004; Gregory Bulit aff005; Dominique Legros aff006; Peter Maes aff002; Francesco Checchi aff007; Oliver Cumming aff001
Působiště autorů: Department of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom aff001; Environmental Health Unit, Médecins Sans Frontières, Brussels, Belgium aff002; LuxOR, Luxembourg Operational Research Unit, Médecins Sans Frontières, Luxembourg aff003; Public Health Unit, Médecins Sans Frontières, Amsterdam, Netherlands aff004; Water, Sanitation and Hygiene, UNICEF, New York, New York, United States of America aff005; Global Task Force on Cholera Control, World Health Organization, Geneva, Switzerland aff006; Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom aff007
Vyšlo v časopise: PLoS ONE 15(1)
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pone.0226549Souhrn
Introduction
Cholera remains a frequent cause of outbreaks globally, particularly in areas with inadequate water, sanitation and hygiene (WASH) services. Cholera is spread through faecal-oral routes, and studies demonstrate that ingestion of Vibrio cholerae occurs from consuming contaminated food and water, contact with cholera cases and transmission from contaminated environmental point sources. WASH guidelines recommending interventions for the prevention and control of cholera are numerous and vary considerably in their recommendations. To date, there has been no review of practice guidelines used in cholera prevention and control programmes.
Methods
We systematically searched international agency websites to identify WASH intervention guidelines used in cholera programmes in endemic and epidemic settings. Recommendations listed in the guidelines were extracted, categorised and analysed. Analysis was based on consistency, concordance and recommendations were classified on the basis of whether the interventions targeted within-household or community-level transmission.
Results
Eight international guidelines were included in this review: three by non-governmental organisations (NGOs), one from a non-profit organisation (NPO), three from multilateral organisations and one from a research institution. There were 95 distinct recommendations identified, and concordance among guidelines was poor to fair. All categories of WASH interventions were featured in the guidelines. The majority of recommendations targeted community-level transmission (45%), 35% targeted within-household transmission and 20% both.
Conclusions
Recent evidence suggests that interventions for effective cholera control and response to epidemics should focus on case-centred approaches and within-household transmission. Guidelines did consistently propose interventions targeting transmission within households. However, the majority of recommendations listed in guidelines targeted community-level transmission and tended to be more focused on preventing contamination of the environment by cases or recurrent outbreaks, and the level of service required to interrupt community-level transmission was often not specified. The guidelines in current use were varied and interpretation may be difficult when conflicting recommendations are provided. Future editions of guidelines should reflect on the inclusion of evidence-based approaches, cholera transmission models and resource-efficient strategies.
Klíčová slova:
Water resources – Sanitation – Hygiene – Disinfection – Water quality – Surface water – Cholera – Water management
Zdroje
1. Legros D, Partners of the Global Task Force on Cholera C. Global Cholera Epidemiology: Opportunities to Reduce the Burden of Cholera by 2030. J Infect Dis. 2018;218(suppl_3):S137–S40. Epub 2018/09/06. doi: 10.1093/infdis/jiy486 30184102; PubMed Central PMCID: PMC6207143.
2. Spiegel PB, Le P, Ververs MT, Salama P. Occurrence and overlap of natural disasters, complex emergencies and epidemics during the past decade (1995–2004). Confl Health. 2007;1 : 2. doi: 10.1186/1752-1505-1-2 17411460; PubMed Central PMCID: PMC1847810.
3. Checchi F, Gayer M, Freeman Grais R, Mills EJ. Public health in crises-affected populations: a practical guide for decision-makers. London, UK: Humanitarian Practice Network at ODI, 2007.
4. Shannon K, Hast M, Azman AS, Legros D, McKay H, Lessler J. Cholera prevention and control in refugee settings: Successes and continued challenges. PLoS Negl Trop Dis. 2019;13(6):e0007347. Epub 2019/06/21. doi: 10.1371/journal.pntd.0007347 31220084; PubMed Central PMCID: PMC6586254.
5. Connolly MA, Gayer M, Ryan MJ, Salama P, Spiegel P, Heymann DL. Communicable diseases in complex emergencies: impact and challenges. Lancet. 2004;364(9449):1974–83. doi: 10.1016/S0140-6736(04)17481-3 15567014.
6. Connolly MA, Heymann DL. Deadly comrades: war and infectious diseases. Lancet. 2002;360 Suppl:s23–4. doi: 10.1016/s0140-6736(02)11807-1 12504490.
7. Cronin AA, Shrestha D, Cornier N, Abdalla F, Ezard N, Aramburu C. A review of water and sanitation provision in refugee camps in association with selected health and nutrition indicators–the need for integrated service provision. Journal of Water and Health. 2008;6(1):1–13. doi: 10.2166/wh.2007.019 17998603
8. Cronin AA, Shrestha D, Spiegel P, Gore F, Hering H. Quantifying the burden of disease associated with inadequate provision of water and sanitation in selected sub-Saharan refugee camps. Journal of Water and Health. 2009;7(4):557–68. doi: 10.2166/wh.2009.089 19590123
9. Gayer M, Legros D, Formenty P, Connolly MA. Conflict and emerging infectious diseases. Emerg Infect Dis. 2007;13(11):1625–31. doi: 10.3201/eid1311.061093 18217543; PubMed Central PMCID: PMC3375795.
10. Sack DA, Sack RB, Nair GB, Siddique AK. Cholera. Lancet. 2004;363(9404):223–33. doi: 10.1016/s0140-6736(03)15328-7 14738797.
11. Shikanga OT, Mutonga D, Abade M, Amwayi S, Ope M, Limo H, et al. High mortality in a cholera outbreak in western Kenya after post-election violence in 2008. Am J Trop Med Hyg. 2009;81(6):1085–90. Epub 2009/12/10. doi: 10.4269/ajtmh.2009.09-0400 19996441.
12. Spiegel P, Sheik M, Gotway-Crawford C, Salama P. Health programmes and policies associated with decreased mortality in displaced people in postemergency phase camps: a retrospective study. Lancet. 2002;360(9349):1927–34. doi: 10.1016/S0140-6736(02)11915-5 12493259.
13. Spiegel PB, Checchi F, Colombo S, Paik E. Health-care needs of people affected by conflict: future trends and changing frameworks. Lancet. 2010;375(9711):341–5. doi: 10.1016/S0140-6736(09)61873-0 20109961.
14. Toole MJ, Waldman RJ. Prevention of excess mortality in refugee and displaced populations in developing countries. JAMA. 1990;263(24):3296–302. 2348541.
15. Smith KF, Goldberg M, Rosenthal S, Carlson L, Chen J, Chen C, et al. Global rise in human infectious disease outbreaks. J R Soc Interface. 2014;11(101):20140950. doi: 10.1098/rsif.2014.0950 25401184; PubMed Central PMCID: PMC4223919.
16. WHO. Disease outbreaks archive 1996 to present [02/03/17]. Available from: http://www.who.int/csr/don/archive/year/en/.
17. Ganesan D, Gupta SS, Legros D. Cholera surveillance and estimation of burden of cholera. Vaccine. 2019. Epub 2019/07/22. doi: 10.1016/j.vaccine.2019.07.036 31326254.
18. WHO. Cholera 2017. Weekly Epidemiological Record. 2018.
19. Harris JB, LaRocque RC, Qadri F, Ryan ET, Calderwood SB. Cholera. Lancet. 2012;379(9835):2466–76. doi: 10.1016/S0140-6736(12)60436-X 22748592; PubMed Central PMCID: PMC3761070.
20. Ali M, Nelson AR, Lopez AL, Sack DA. Updated global burden of cholera in endemic countries. PLoS Negl Trop Dis. 2015;9(6):e0003832. Epub 2015/06/05. doi: 10.1371/journal.pntd.0003832 26043000; PubMed Central PMCID: PMC4455997.
21. Lessler J, Moore SM, Luquero FJ, McKay HS, Grais R, Henkens M, et al. Mapping the burden of cholera in sub-Saharan Africa and implications for control: an analysis of data across geographical scales. Lancet. 2018. Epub 2018/03/06. doi: 10.1016/S0140-6736(17)33050-7 29502905.
22. Blake A, Keita VS, Sauvageot D, Saliou M, Njanpop BM, Sory F, et al. Temporo-spatial dynamics and behavioural patterns of 2012 cholera epidemic in the African mega-city of Conakry, Guinea. Infect Dis Poverty. 2018;7(1):13. Epub 2018/02/17. doi: 10.1186/s40249-018-0393-8 29448965; PubMed Central PMCID: PMC5815196.
23. Moore S, Dongdem AZ, Opare D, Cottavoz P, Fookes M, Sadji AY, et al. Dynamics of cholera epidemics from Benin to Mauritania. PLoS Negl Trop Dis. 2018;12(4):e0006379. Epub 2018/04/10. doi: 10.1371/journal.pntd.0006379 29630632.
24. Weill FX, Domman D, Njamkepo E, Tarr C, Rauzier J, Fawal N, et al. Genomic history of the seventh pandemic of cholera in Africa. Science. 2017;358(6364):785–9. Epub 2017/11/11. doi: 10.1126/science.aad5901 29123067.
25. Islam MS, Zaman MH, Islam MS, Ahmed N, Clemens JD. Environmental reservoirs of Vibrio cholerae. Vaccine. 2019. Epub 2019/07/10. doi: 10.1016/j.vaccine.2019.06.033 31285087.
26. Tien JH, Earn DJ. Multiple transmission pathways and disease dynamics in a waterborne pathogen model. Bull Math Biol. 2010;72(6):1506–33. doi: 10.1007/s11538-010-9507-6 20143271.
27. Fung IC. Cholera transmission dynamic models for public health practitioners. Emerg Themes Epidemiol. 2014;11(1):1. doi: 10.1186/1742-7622-11-1 24520853; PubMed Central PMCID: PMC3926264.
28. Richterman A, Sainvilien DR, Eberly L, Ivers LC. Individual and Household Risk Factors for Symptomatic Cholera Infection: A Systematic Review and Meta-analysis. J Infect Dis. 2018;218(suppl_3):S154–S64. Epub 2018/08/24. doi: 10.1093/infdis/jiy444 30137536; PubMed Central PMCID: PMC6188541.
29. Deen J, Mengel MA, Clemens JD. Epidemiology of cholera. Vaccine. 2019. Epub 2019/08/10. doi: 10.1016/j.vaccine.2019.07.078 31395455.
30. Shapiro RL, Otieno MR, Adcock PM, Phillips-Howard PA, Hawley WA, Kumar L, et al. Transmission of epidemic Vibrio cholerae O1 in rural western Kenya associated with drinking water from Lake Victoria: an environmental reservoir for cholera? Am J Trop Med Hyg. 1999;60(2):271–6. doi: 10.4269/ajtmh.1999.60.271 10072150.
31. Swerdlow DL, Malenga G, Begkoyian G, Nyangulu D, Toole M, Waldman RJ, et al. Epidemic cholera among refugees in Malawi, Africa: treatment and transmission. Epidemiol Infect. 1997;118(3):207–14. Epub 1997/06/01. doi: 10.1017/s0950268896007352 9207730; PubMed Central PMCID: PMC2808810.
32. Nguyen VD, Sreenivasan N, Lam E, Ayers T, Kargbo D, Dafae F, et al. Cholera epidemic associated with consumption of unsafe drinking water and street-vended water—Eastern Freetown, Sierra Leone, 2012. Am J Trop Med Hyg. 2014;90(3):518–23. Epub 2014/01/29. doi: 10.4269/ajtmh.13-0567 24470563; PubMed Central PMCID: PMC3945698.
33. Acosta CJ, Galindo CM, Kimario J, Senkoro K, Urassa H, Casals C, et al. Cholera outbreak in southern Tanzania: risk factors and patterns of transmission. Emerg Infect Dis. 2001;7(3 Suppl):583–7. doi: 10.3201/eid0707.010741 11485679; PubMed Central PMCID: PMC2631835.
34. DuBois AE, Sinkala M, Kalluri P, Makasa-Chikoya M, Quick RE. Epidemic cholera in urban Zambia: hand soap and dried fish as protective factors. Epidemiol Infect. 2006;134(6):1226–30. doi: 10.1017/S0950268806006273 16623992; PubMed Central PMCID: PMC2870514.
35. Moradi G, Rasouli MA, Mohammadi P, Elahi E, Barati H. A cholera outbreak in Alborz Province, Iran: a matched case-control study. Epidemiol Health. 2016;38:e2016018. doi: 10.4178/epih.e2016018 27188308; PubMed Central PMCID: PMC4967910.
36. Ujjiga TT, Wamala JF, Mogga JJ, Othwonh TO, Mutonga D, Kone-Coulibaly A, et al. Risk Factors for Sustained Cholera Transmission, Juba County, South Sudan, 2014. Emerg Infect Dis. 2015;21(10):1849–52. Epub 2015/09/25. doi: 10.3201/eid2110.142051 26402715; PubMed Central PMCID: PMC4593433.
37. Burrowes V, Perin J, Monira S, Sack D, Rashid MU, Mahamud T, et al. Risk Factors for Household Transmission of Vibrio cholerae in Dhaka, Bangladesh (CHoBI7 Trial). Am J Trop Med Hyg. 2017. doi: https://doi.org/10.4269/ajtmh.16-0871.
38. Fredrick T, Ponnaiah M, Murhekar MV, Jayaraman Y, David JK, Vadivoo S, et al. Cholera outbreak linked with lack of safe water supply following a tropical cyclone in Pondicherry, India, 2012. J Health Popul Nutr. 2015;33(1):31–8. Epub 2015/05/23. 25995719; PubMed Central PMCID: PMC4438646.
39. Grandesso F, Allan M, Jean-Simon PS, Boncy J, Blake A, Pierre R, et al. Risk factors for cholera transmission in Haiti during inter-peak periods: insights to improve current control strategies from two case-control studies. Epidemiol Infect. 2014;142(8):1625–35. doi: 10.1017/S0950268813002562 24112364.
40. Rodrigues A, Sandstrom A, Ca T, Steinsland H, Jensen H, Aaby P. Protection from cholera by adding lime juice to food—results from community and laboratory studies in Guinea-Bissau, West Africa. Trop Med Int Health. 2000;5(6):418–22. doi: 10.1046/j.1365-3156.2000.00575.x 10929141.
41. Rashid MU, Rahman Z, Burrowes V, Perin J, Mustafiz M, Monira S, et al. Rapid dipstick detection of Vibrio cholerae in household stored and municipal water in Dhaka, Bangladesh: CHoBI7 trial. Trop Med Int Health. 2017;22(2):205–9. doi: 10.1111/tmi.12797 27754582.
42. Rashid MU, George CM, Monira S, Mahmud T, Rahman Z, Mustafiz M, et al. Chlorination of Household Drinking Water Among Cholera Patients' Households to Prevent Transmission of Toxigenic Vibrio cholerae in Dhaka, Bangladesh: CHoBI7 Trial. Am J Trop Med Hyg. 2016;95(6):1299–304. doi: 10.4269/ajtmh.16-0420 27698273; PubMed Central PMCID: PMC5154443.
43. Sugimoto JD, Koepke AA, Kenah EE, Halloran ME, Chowdhury F, Khan AI, et al. Household Transmission of Vibrio cholerae in Bangladesh. PLOS Neglected Tropical Diseases. 2014;8(11):e3314. doi: 10.1371/journal.pntd.0003314 25411971
44. Rebaudet S, Bulit G, Gaudart J, Michel E, Gazin P, Evers C, et al. The case-area targeted rapid response strategy to control cholera in Haiti: a four-year implementation study. PLoS Negl Trop Dis. 2019;13(4):e0007263. Epub 2019/04/17. doi: 10.1371/journal.pntd.0007263 30990822.
45. Mukandavire Z, Morris JG. Modeling the Epidemiology of Cholera to Prevent Disease Transmission in Developing Countries. Microbiology spectrum. 2015;3(3):10.1128/microbiolspec.VE-0011-2014. doi: 10.1128/microbiolspec.VE-0011-2014 PMC4634708. 26185087
46. Wagner EG, Lanoix JN. Excreta disposal for rural areas and small communities. Monogr Ser World Health Organ. 1958;39 : 1–182. 13581743.
47. Codeço CT, Coelho FC. Trends in cholera epidemiology. PLoS Med. 2006;3(1):e42. doi: 10.1371/journal.pmed.0030042 16435891; PubMed Central PMCID: PMC1360632.
48. Debes AK, Ali M, Azman AS, Yunus M, Sack DA. Cholera cases cluster in time and space in Matlab, Bangladesh: implications for targeted preventive interventions. Int J Epidemiol. 2016. doi: 10.1093/ije/dyw267 27789673.
49. Finger F, Bertuzzo E, Luquero FJ, Naibei N, Touré B, Allan M, et al. The potential impact of case-area targeted interventions in response to cholera outbreaks: A modeling study. PLOS Medicine. 2018;15(2):e1002509. doi: 10.1371/journal.pmed.1002509 29485987
50. Bi Q, Azman AS, Satter SM, Khan AI, Ahmed D, Riaj AA, et al. Micro-scale Spatial Clustering of Cholera Risk Factors in Urban Bangladesh. PLoS Negl Trop Dis. 2016;10(2):e0004400. Epub 2016/02/13. doi: 10.1371/journal.pntd.0004400 26866926; PubMed Central PMCID: PMC4750854.
51. Chowdhury F, Mather AE, Begum YA, Asaduzzaman M, Baby N, Sharmin S, et al. Vibrio cholerae Serogroup O139: Isolation from Cholera Patients and Asymptomatic Household Family Members in Bangladesh between 2013 and 2014. PLoS Negl Trop Dis. 2015;9(11):e0004183. Epub 2015/11/13. doi: 10.1371/journal.pntd.0004183 26562418; PubMed Central PMCID: PMC4642977.
52. Weil AA, Begum Y, Chowdhury F, Khan AI, Leung DT, LaRocque RC, et al. Bacterial shedding in household contacts of cholera patients in Dhaka, Bangladesh. Am J Trop Med Hyg. 2014;91(4):738–42. doi: 10.4269/ajtmh.14-0095 25114012; PubMed Central PMCID: PMC4183396.
53. Phelps MD, Azman AS, Lewnard JA, Antillon M, Simonsen L, Andreasen V, et al. The importance of thinking beyond the water-supply in cholera epidemics: A historical urban case-study. PLoS Negl Trop Dis. 2017;11(11):e0006103. Epub 2017/11/28. doi: 10.1371/journal.pntd.0006103 29176791; PubMed Central PMCID: PMC5720805.
54. Blackburn JK, Diamond U, Kracalik IT, Widmer J, Brown W, Morrissey BD, et al. Household-level spatiotemporal patterns of incidence of cholera, Haiti, 2011. Emerg Infect Dis. 2014;20(9):1516–9. Epub 2014/08/26. doi: 10.3201/eid2009.131882 25148590; PubMed Central PMCID: PMC4178390.
55. Domman D, Chowdhury F, Khan AI, Dorman MJ, Mutreja A, Uddin MI, et al. Defining endemic cholera at three levels of spatiotemporal resolution within Bangladesh. Nat Genet. 2018;50(7):951–5. Epub 2018/06/27. doi: 10.1038/s41588-018-0150-8 29942084; PubMed Central PMCID: PMC6283067.
56. George CM, Hasan K, Monira S, Rahman Z, Saif-Ur-Rahman KM, Rashid MU, et al. A prospective cohort study comparing household contact and water Vibrio cholerae isolates in households of cholera patients in rural Bangladesh. PLoS Negl Trop Dis. 2018;12(7):e0006641. Epub 2018/07/28. doi: 10.1371/journal.pntd.0006641 30052631; PubMed Central PMCID: PMC6063393.
57. Rafique R, Rashid MU, Monira S, Rahman Z, Mahmud MT, Mustafiz M, et al. Transmission of Infectious Vibrio cholerae through Drinking Water among the Household Contacts of Cholera Patients (CHoBI7 Trial). Front Microbiol. 2016;7 : 1635. doi: 10.3389/fmicb.2016.01635 27803695; PubMed Central PMCID: PMC5067524.
58. George CM, Rashid M, Almeida M, Saif-Ur-Rahman KM, Monira S, Bhuyian MSI, et al. Genetic relatedness of Vibrio cholerae isolates within and between households during outbreaks in Dhaka, Bangladesh. BMC Genomics. 2017;18(1):903. Epub 2017/11/28. doi: 10.1186/s12864-017-4254-9 29178823; PubMed Central PMCID: PMC5702050.
59. Andrews JR, Basu S. Transmission dynamics and control of cholera in Haiti: an epidemic model. Lancet. 2011;377(9773):1248–55. doi: 10.1016/S0140-6736(11)60273-0 21414658; PubMed Central PMCID: PMC3172163.
60. Hartley DM, Morris JG Jr., Smith DL. Hyperinfectivity: a critical element in the ability of V. cholerae to cause epidemics? PLoS Med. 2006;3(1):e7. doi: 10.1371/journal.pmed.0030007 16318414; PubMed Central PMCID: PMC1298942.
61. Codeço CT. Endemic and epidemic dynamics of cholera: the role of the aquatic reservoir. BMC Infect Dis. 2001;1 : 1. doi: 10.1186/1471-2334-1-1 11208258; PubMed Central PMCID: PMC29087.
62. Grad YH, Miller JC, Lipsitch M. Cholera modeling: challenges to quantitative analysis and predicting the impact of interventions. Epidemiology. 2012;23(4):523–30. doi: 10.1097/EDE.0b013e3182572581 22659546; PubMed Central PMCID: PMC3380087.
63. George CM, Monira S, Sack DA, Rashid MU, Saif-Ur-Rahman KM, Mahmud T, et al. Randomized Controlled Trial of Hospital-Based Hygiene and Water Treatment Intervention (CHoBI7) to Reduce Cholera. Emerg Infect Dis. 2016;22(2):233–41. Epub 2016/01/27. doi: 10.3201/eid2202.151175 26811968; PubMed Central PMCID: PMC4734520.
64. Montgomery M, Jones MW, Kabole I, Johnston R, Gordon B. No end to cholera without basic water, sanitation and hygiene. Bull World Health Organ. 2018;96(6):371-A. Epub 2018/06/16. doi: 10.2471/BLT.18.213678 29904216; PubMed Central PMCID: PMC5996206.
65. Azman AS, Parker LA, Rumunu J, Tadesse F, Grandesso F, Deng LL, et al. Effectiveness of one dose of oral cholera vaccine in response to an outbreak: a case-cohort study. Lancet Glob Health. 2016;4(11):e856–e63. doi: 10.1016/S2214-109X(16)30211-X 27765293.
66. Khan MU, Shahidullah M. Role of water and sanitation in the incidence of cholera in refugee camps. Trans R Soc Trop Med Hyg. 1982;76(3):373–7. Epub 1982/01/01. doi: 10.1016/0035-9203(82)90194-8 7112660.
67. von Seidlein L, Deen JL. Preventing cholera outbreaks through early targeted interventions. PLoS Med. 2018;15(2):e1002510. Epub 2018/02/28. doi: 10.1371/journal.pmed.1002510 29485984; PubMed Central PMCID: PMC5828352.
68. Global Task Force on Cholera Control. Ending Cholera: A Global Roadmap to 2030. 2017.
69. Najnin N, Leder K, Qadri F, Forbes A, Unicomb L, Winch PJ, et al. Impact of adding hand-washing and water disinfection promotion to oral cholera vaccination on diarrhoea-associated hospitalization in Dhaka, Bangladesh: evidence from a cluster randomized control trial. Int J Epidemiol. 2017;46(6):2056–66. Epub 2017/10/13. doi: 10.1093/ije/dyx187 29025064; PubMed Central PMCID: PMC5837384.
70. Taylor DL, Kahawita TM, Cairncross S, Ensink JH. The Impact of Water, Sanitation and Hygiene Interventions to Control Cholera: A Systematic Review. PLoS One. 2015;10(8):e0135676. Epub 2015/08/19. doi: 10.1371/journal.pone.0135676 26284367; PubMed Central PMCID: PMC4540465.
71. Huq A, Yunus M, Sohel SS, Bhuiya A, Emch M, Luby SP, et al. Simple sari cloth filtration of water is sustainable and continues to protect villagers from cholera in Matlab, Bangladesh. MBio. 2010;1(1). Epub 2010/08/07. doi: 10.1128/mBio.00034-10 20689750; PubMed Central PMCID: PMC2912662.
72. Colwell RR, Huq A, Islam MS, Aziz KM, Yunus M, Khan NH, et al. Reduction of cholera in Bangladeshi villages by simple filtration. Proc Natl Acad Sci U S A. 2003;100(3):1051–5. Epub 2003/01/17. doi: 10.1073/pnas.0237386100 12529505; PubMed Central PMCID: PMC298724.
73. Conroy RM, Meegan ME, Joyce T, McGuigan K, Barnes J. Solar disinfection of drinking water protects against cholera in children under 6 years of age. Arch Dis Child. 2001;85(4):293–5. Epub 2001/09/25. doi: 10.1136/adc.85.4.293 11567937; PubMed Central PMCID: PMC1718943.
74. Deb BC, Sircar BK, Sengupta PG, De SP, Mondal SK, Gupta DN, et al. Studies on interventions to prevent eltor cholera transmission in urban slums. Bull World Health Organ. 1986;64(1):127–31. Epub 1986/01/01. 3488134; PubMed Central PMCID: PMC2490926.
75. Azurin JC, Alvero M. Field evaluation of environmental sanitation measures against cholera. Bull World Health Organ. 1974;51(1):19–26. Epub 1974/01/01. 4549038; PubMed Central PMCID: PMC2366240.
76. Lantagne D, Yates T. Household Water Treatment and Cholera Control. J Infect Dis. 2018;218(suppl_3):S147–S53. Epub 2018/09/15. doi: 10.1093/infdis/jiy488 30215739; PubMed Central PMCID: PMC6188534.
77. Patrick M, Berendes D, Murphy J, Bertrand F, Husain F, Handzel T. Access to safe water in rural Artibonite, Haiti 16 months after the onset of the cholera epidemic. Am J Trop Med Hyg. 2013;89(4):647–53. doi: 10.4269/ajtmh.13-0308 24106191; PubMed Central PMCID: PMC3795094.
78. Gartley M, Valeh P, de Lange R, Dicarlo S, Viscusi A, Lenglet A, et al. Uptake of household disinfection kits as an additional measure in response to a cholera outbreak in urban areas of Haiti. J Water Health. 2013;11(4):623–8. doi: 10.2166/wh.2013.050 24334836.
79. Lantagne DS, Clasen TF. Use of Household Water Treatment and Safe Storage Methods in Acute Emergency Response: Case Study Results from Nepal, Indonesia, Kenya, and Haiti. Environmental Science & Technology. 2012;46(20):11352–60. WOS:000309805000065.
80. Cavallaro EC, Harris JR, da Goia MS, dos Santos Barrado JC, da Nobrega AA, de Alvarenga de Junior IC, et al. Evaluation of pot-chlorination of wells during a cholera outbreak, Bissau, Guinea-Bissau, 2008. J Water Health. 2011;9(2):394–402. doi: 10.2166/wh.2011.122 21942203.
81. Beau De Rochars VE, Tipret J, Patrick M, Jacobson L, Barbour KE, Berendes D, et al. Knowledge, attitudes, and practices related to treatment and prevention of cholera, Haiti, 2010. Emerg Infect Dis. 2011;17(11):2158–61. Epub 2011/12/30. doi: 10.3201/eid1711.110818 22204033; PubMed Central PMCID: PMC3310585.
82. Steele A, Clarke B, Watkins O. Impact of jerry can disinfection in a camp environment—experiences in an IDP camp in Northern Uganda. J Water Health. 2008;6(4):559–64. doi: 10.2166/wh.2008.072 18401121.
83. Guévart E, Van Hecke, C., Noeske J., Sollé J., Bita Fouda, A., Manga B. Diffuseur artisanal de chlore pour désinfecter les puits lors de l'épidémie de choléra de Douala (2004). / [Handmade devices for continuous delivery of hypochlorite for well disinfection during the cholera outbreak in Douala, Cameroon (2004)]. Med Trop (Mars). 2008;68(5):507–13.
84. Garandeau R, Trevett A., Bastable A. Cholrination of hand-dug wells in Monrovia. Waterlines. 2006;24(3):19–21.
85. Einarsdottir J, Passa A, Gunnlaugsson G. Health education and cholera in rural Guinea-bissau. Int J Infect Dis. 2001;5(3):133–8. doi: 10.1016/s1201-9712(01)90087-6 11724669.
86. Dunston C, McAfee D, Kaiser R, Rakotoarison D, Rambeloson L, Hoang AT, et al. Collaboration, cholera, and cyclones: a project to improve point-of-use water quality in Madagascar. Am J Public Health. 2001;91(10):1574–6. doi: 10.2105/ajph.91.10.1574 11574309; PubMed Central PMCID: PMC1446828.
87. Quick RE, Venczel LV, Gonzalez O, Mintz ED, Highsmith AK, Espada A, et al. Narrow-mouthed water storage vessels and in situ chlorination in a Bolivian community: a simple method to improve drinking water quality. Am J Trop Med Hyg. 1996;54(5):511–6. Epub 1996/05/01. doi: 10.4269/ajtmh.1996.54.511 8644907.
88. Quick RE, Gerber ML, Palacios AM, Beingolea L, Vargas R, Mujica O, et al. Using a knowledge, attitudes and practices survey to supplement findings of an outbreak investigation: cholera prevention measures during the 1991 epidemic in Peru. Int J Epidemiol. 1996;25(4):872–8. doi: 10.1093/ije/25.4.872 8921469.
89. Mahadik VJ, Mbomena J. Impact of health education programme on knowledge, attitude and practice (KAP) of people in cholera affected areas of Luapula Province—Zambia. Med J Zambia. 1983;17(2):32–8. 6678090.
90. D’Mello-Guyett L, Yates T, Bastable A, Dahab M, Deola C, Dorea C, et al. Setting priorities for humanitarian water, sanitation and hygiene research: a meeting report. Conflict and Health. 2018;12(1). doi: 10.1186/s13031-018-0159-8
91. Grimshaw JM, Russell IT. Effect of clinical guidelines on medical practice: a systematic review of rigorous evaluations. Lancet. 1993;342(8883):1317–22. Epub 1993/11/27. doi: 10.1016/0140-6736(93)92244-n 7901634.
92. Djulbegovic B, Guyatt GH. Progress in evidence-based medicine: a quarter century on. Lancet. 2017;390(10092):415–23. Epub 2017/02/22. doi: 10.1016/S0140-6736(16)31592-6 28215660.
93. WHO. WHO Handbook for Guideline Development. Geneva, Switzerland: 2014.
94. Tricco AC, Lillie E, Zarin W, O'Brien KK, Colquhoun H, Levac D, et al. PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation. Ann Intern Med. 2018;169(7):467–73. Epub 2018/09/05. doi: 10.7326/M18-0850 30178033.
95. Dangour AD, Watson L, Cumming O, Boisson S, Che Y, Velleman Y, et al. Interventions to improve water quality and supply, sanitation and hygiene practices, and their effects on the nutritional status of children. Cochrane Database Syst Rev. 2013;(8):CD009382. doi: 10.1002/14651858.CD009382.pub2 23904195.
96. Piper JD, Chandna J, Allen E, Linkman K, Cumming O, Prendergast AJ, et al. Water, sanitation and hygiene (WASH) interventions: effects on child development in low - and middle-income countries. Cochrane Db Syst Rev. 2017. doi: 10.1002/14651858.Cd012613
97. Fleiss JL, Nee JM, Paik MC. Statistical methods for rates and proportions. 3rd Edition ed. New York, USA: Wiley; 2003.
98. Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33(1):159–74. Epub 1977/03/01. 843571.
99. Mukandavire Z, Liao S, Wang J, Gaff H, Smith DL, Morris JG Jr. Estimating the reproductive numbers for the 2008–2009 cholera outbreaks in Zimbabwe. Proc Natl Acad Sci U S A. 2011;108(21):8767–72. Epub 2011/04/27. doi: 10.1073/pnas.1019712108 21518855; PubMed Central PMCID: PMC3102413.
100. MSF. Management of a Cholera Epidemic. Médecins Sans Frontières, 2017.
101. Oxfam. Cholera Outbreak Guidelines: Preparedness, Prevention and Control. Oxford, UK: Oxfam, 2012.
102. ACF. Manuel Pratique: Eau, Assainissement, Hygiène dans la Lutte Contre le Choléra. Paris, France: Action Contre la Faim, 2013.
103. Sphere. The Sphere Project: Humanitarian Charter and Minimum Standards in Humanitarian Response. Geneva, Switzerland: 2018.
104. UNICEF. Cholera Toolkit. New York, USA: United Nations Children's Fund, 2013.
105. WHO. Cholera Outbreak, Assessing the Outbreak Response and Improving Preparedness. Geneva, Switzerland: World Health Organisation, 2004.
106. Global Task Force on Cholera Control. Cholera Outbreak Response: Field Manual (January 2019 Prepress Copy). Geneva, Switzerland: WHO, 2019.
107. ICDDR'B. COTS Program 2.0. Dhaka, Bangladesh: 2018.
108. The Lancet. Cholera: ending a 50-year pandemic. The Lancet. 2017;390.
109. Phelps M, Perner ML, Pitzer VE, Andreasen V, Jensen PKM, Simonsen L. Cholera Epidemics of the Past Offer New Insights Into an Old Enemy. J Infect Dis. 2018;217(4):641–9. Epub 2017/11/23. doi: 10.1093/infdis/jix602 29165706; PubMed Central PMCID: PMC5853221.
110. Yates T, Vujcic JA, Joseph ML, Gallandat K, Lantagne D. Water, sanitation, and hygiene interventions in outbreak response: a synthesis of evidence. Waterlines. 2018;37(1):5–30. doi: 10.3362/1756-3488.17–00015
111. Wolf J, Hunter PR, Freeman MC, Cumming O, Clasen T, Bartram J, et al. Impact of Drinking Water, Sanitation and Hand Washing with Soap on Childhood Diarrhoeal Disease: Updated Meta-Analysis and -Regression. Trop Med Int Health. 2018. Epub 2018/03/15. doi: 10.1111/tmi.13051 29537671.
112. Esteves Mills J, Cumming O. The impact of water, sanitation and hygiene on key health and social outcomes: review of evidence. London, UK: SHARE & LSHTM, 2016.
113. Saif-Ur-Rahman KM, Parvin T, Bhuyian SI, Zohura F, Begum F, Rashid MU, et al. Promotion of Cholera Awareness Among Households of Cholera Patients: A Randomized Controlled Trial of the Cholera-Hospital-Based-Intervention-for-7 Days (CHoBI7) Intervention. Am J Trop Med Hyg. 2016;95(6):1292–8. doi: 10.4269/ajtmh.16-0378 27799644; PubMed Central PMCID: PMC5154442.
114. Merrell DS, Butler SM, Qadri F, Dolganov NA, Alam A, Cohen MB, et al. Host-induced epidemic spread of the cholera bacterium. Nature. 2002;417(6889):642–5. doi: 10.1038/nature00778 12050664; PubMed Central PMCID: PMC2776822.
115. Greenland K, Chipungu J, Curtis V, Schmidt WP, Siwale Z, Mudenda M, et al. Multiple behaviour change intervention for diarrhoea control in Lusaka, Zambia: a cluster randomised trial. Lancet Glob Health. 2016;4(12):e966–e77. Epub 2016/11/20. doi: 10.1016/S2214-109X(16)30262-5 27855872.
116. Tidwell JB, Gopalakrishnan A, Lovelady S, Sheth E, Unni A, Wright R, et al. Effect of Two Complementary Mass-Scale Media Interventions on Handwashing with Soap among Mothers. J Health Commun. 2019;24(2):203–15. Epub 2019/03/27. doi: 10.1080/10810730.2019.1593554 30912707.
117. Hirai M, Graham JP, Mattson KD, Kelsey A, Mukherji S, Cronin AA. Exploring Determinants of Handwashing with Soap in Indonesia: A Quantitative Analysis. Int J Environ Res Public Health. 2016;13(9). Epub 2016/09/07. doi: 10.3390/ijerph13090868 27598178; PubMed Central PMCID: PMC5036701.
118. Rabbi SE, Dey NC. Exploring the gap between hand washing knowledge and practices in Bangladesh: a cross-sectional comparative study. BMC Public Health. 2013;13 : 89. Epub 2013/02/01. doi: 10.1186/1471-2458-13-89 23363772; PubMed Central PMCID: PMC3564897.
119. Biran A, Schmidt WP, Wright R, Jones T, Seshadri M, Isaac P, et al. The effect of a soap promotion and hygiene education campaign on handwashing behaviour in rural India: a cluster randomised trial. Trop Med Int Health. 2009;14(10):1303–14. Epub 2009/08/28. doi: 10.1111/j.1365-3156.2009.02373.x 19708896.
120. Freeman MC, Stocks ME, Cumming O, Jeandron A, Higgins JP, Wolf J, et al. Hygiene and health: systematic review of handwashing practices worldwide and update of health effects. Trop Med Int Health. 2014;19(8):906–16. doi: 10.1111/tmi.12339 24889816.
121. George CM, Zohura F, Teman A, Thomas E, Hasan T, Rana S, et al. Formative research for the design of a scalable water, sanitation, and hygiene mobile health program: CHoBI7 mobile health program. BMC Public Health. 2019;19(1):1028. Epub 2019/08/02. doi: 10.1186/s12889-019-7144-z 31366398; PubMed Central PMCID: PMC6670164.
122. George CM, Sack DA. Integration of water, sanitation and hygiene intervention delivery at health facilities with a reactive ring vaccination programme to reduce cholera. Int J Epidemiol. 2017;46(6):2093–4. Epub 2017/03/25. doi: 10.1093/ije/dyx025 28338776.
123. Roskosky M, Acharya B, Shakya G, Karki K, Sekine K, Bajracharya D, et al. Feasibility of a Comprehensive Targeted Cholera Intervention in The Kathmandu Valley, Nepal. Am J Trop Med Hyg. 2019;100(5):1088–97. Epub 2019/03/20. doi: 10.4269/ajtmh.18-0863 30887946; PubMed Central PMCID: PMC6493959.
124. Parker AA, Stephenson R, Riley PL, Ombeki S, Komolleh C, Sibley L, et al. Sustained high levels of stored drinking water treatment and retention of hand-washing knowledge in rural Kenyan households following a clinic-based intervention. Epidemiol Infect. 2006;134(5):1029–36. Epub 2006/01/28. doi: 10.1017/S0950268806005954 16438747; PubMed Central PMCID: PMC2870483.
125. Briere EC, Ryman TK, Cartwright E, Russo ET, Wannemuehler KA, Nygren BL, et al. Impact of integration of hygiene kit distribution with routine immunizations on infant vaccine coverage and water treatment and handwashing practices of Kenyan mothers. J Infect Dis. 2012;205 Suppl 1:S56–64. Epub 2012/02/15. doi: 10.1093/infdis/jir779 22315387.
126. Kern E, Verguet S, Yuhas K, Odhiambo FH, Kahn JG, Walson J. Provision of bednets and water filters to delay HIV-1 progression: cost-effectiveness analysis of a Kenyan multisite study. Trop Med Int Health. 2013;18(8):916–24. Epub 2013/05/11. doi: 10.1111/tmi.12127 23659539.
127. Azman AS, Luquero FJ, Salje H, Naibei Mbaibardoum N, Adalbert N, Ali M, et al. Micro-hotspots of Risk in Urban Cholera Epidemics. J Infect Dis. 2018. Epub 2018/05/15. doi: 10.1093/infdis/jiy283 29757428.
128. Bwire G, Ali M, Sack DA, Nakinsige A, Naigaga M, Debes AK, et al. Identifying cholera "hotspots" in Uganda: An analysis of cholera surveillance data from 2011 to 2016. PLoS Negl Trop Dis. 2017;11(12):e0006118. Epub 2017/12/29. doi: 10.1371/journal.pntd.0006118 29284003; PubMed Central PMCID: PMC5746206.
129. Bwire G, Debes AK, Orach CG, Kagirita A, Ram M, Komakech H, et al. Environmental Surveillance of Vibrio cholerae O1/O139 in the Five African Great Lakes and Other Major Surface Water Sources in Uganda. Front Microbiol. 2018;9 : 1560. Epub 2018/08/21. doi: 10.3389/fmicb.2018.01560 30123189; PubMed Central PMCID: PMC6085420.
130. Rebaudet S, Sudre B, Faucher B, Piarroux R. Environmental determinants of cholera outbreaks in inland Africa: a systematic review of main transmission foci and propagation routes. J Infect Dis. 2013;208 Suppl 1:S46–54. doi: 10.1093/infdis/jit195 24101645.
131. Nelson EJ, Harris JB, Morris JG Jr., Calderwood SB, Camilli A. Cholera transmission: the host, pathogen and bacteriophage dynamic. Nat Rev Microbiol. 2009;7(10):693–702. doi: 10.1038/nrmicro2204 19756008; PubMed Central PMCID: PMC3842031.
132. Luby SP, Davis J, Brown RR, Gorelick SM, Wong THF. Broad approaches to cholera control in Asia: Water, sanitation and handwashing. Vaccine. 2019. Epub 2019/08/07. doi: 10.1016/j.vaccine.2019.07.084 31383486.
133. Garn JV, Sclar GD, Freeman MC, Penakalapati G, Alexander KT, Brooks P, et al. The impact of sanitation interventions on latrine coverage and latrine use: A systematic review and meta-analysis. Int J Hyg Environ Health. 2017;220(2 Pt B):329–40. Epub 2016/11/09. doi: 10.1016/j.ijheh.2016.10.001 27825597; PubMed Central PMCID: PMC5414716.
134. Tamason CC, Bessias S, Villada A, Tulsiani SM, Ensink JH, Gurley ES, et al. Measuring domestic water use: a systematic review of methodologies that measure unmetered water use in low-income settings. Trop Med Int Health. 2016. doi: 10.1111/tmi.12769 27573762.
135. Stelmach RD, Clasen T. Household water quantity and health: a systematic review. Int J Environ Res Public Health. 2015;12(6):5954–74. doi: 10.3390/ijerph120605954 26030467; PubMed Central PMCID: PMC4483681.
136. De Buck E, Borra V, De Weerdt E, Vande Veegaete A, Vandekerckhove P. A systematic review of the amount of water per person per day needed to prevent morbidity and mortality in (post-)disaster settings. PLoS ONE. 2015;10(5). doi: 10.1371/journal.pone.0126395 25961720
137. Pickering AJ, Davis J. Freshwater availability and water fetching distance affect child health in sub-Saharan Africa. Environ Sci Technol. 2012;46(4):2391–7. doi: 10.1021/es203177v 22242546.
138. Paneth N. Assessing the contributions of John Snow to epidemiology: 150 years after removal of the broad street pump handle. Epidemiology. 2004;15(5):514–6. 15308944.
139. WHO. Guidelines for drinking water quality, 4th edition, incorportating the 1st addendum2017. 631 p.
140. Jeandron A, Saidi JM, Kapama A, Burhole M, Birembano F, Vandevelde T, et al. Water supply interruptions and suspected cholera incidence: a time-series regression in the Democratic Republic of the Congo. PLoS Med. 2015;12(10):e1001893. Epub 2015/10/28. doi: 10.1371/journal.pmed.1001893 26506001; PubMed Central PMCID: PMC4624412.
141. White G, Bradley W, White A. Drawers of Water: Domestic water use in East Africa. Chicago, USA: The University of Chicago Press, Chicago; 1972.
142. UN. Sustainable Development Goals: UN; 2015 [cited 2016 02 Sept 2016]. Available from: https://sustainabledevelopment.un.org/?menu=1300.
143. Nygren BL, Blackstock AJ, Mintz ED. Cholera at the crossroads: the association between endemic cholera and national access to improved water sources and sanitation. Am J Trop Med Hyg. 2014;91(5):1023–8. Epub 2014/09/10. doi: 10.4269/ajtmh.14-0331 25200265; PubMed Central PMCID: PMC4228869.
144. WHO/UNICEF. Sustainable Development Goals - Goal 6: Ensure availability and sustainable management of water and sanitation for all Geneva, Switzerland2018 [13/05/2019]. Available from: https://unstats.un.org/sdgs/report/2018/goal-06/.
145. WHO/UNICEF. Progress on Sanitation and Drinking Water: 2015 Update and MDG Assessment. Geneva, Switzerland: World Health Organization & United Nations Children's Fund, 2015.
146. JMP. WHO/UNICEF Joint Monitoring Programme for Water Supply, Sanitation and Hygiene 2015. Available from: https://washdata.org/monitoring.
147. Colwell RR. Global climate and infectious disease: the cholera paradigm. Science. 1996;274(5295):2025–31. doi: 10.1126/science.274.5295.2025 8953025.
148. Lipp EK, Huq A, Colwell RR. Effects of global climate on infectious disease: the cholera model. Clin Microbiol Rev. 2002;15(4):757–70. Epub 2002/10/05. doi: 10.1128/CMR.15.4.757-770.2002 12364378; PubMed Central PMCID: PMC126864.
149. Stoltzfus JD, Carter JY, Akpinar-Elci M, Matu M, Kimotho V, Giganti MJ, et al. Interaction between climatic, environmental, and demographic factors on cholera outbreaks in Kenya. Infect Dis Poverty. 2014;3(1):37. doi: 10.1186/2049-9957-3-37 25328678; PubMed Central PMCID: PMC4200235.
150. Petticrew M, Knai C, Thomas J, Rehfuess EA, Noyes J, Gerhardus A, et al. Implications of a complexity perspective for systematic reviews and guideline development in health decision making. BMJ Glob Health. 2019;4(Suppl 1):e000899. Epub 2019/02/19. doi: 10.1136/bmjgh-2018-000899 30775017; PubMed Central PMCID: PMC6350708.
151. Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336(7650):924–6. Epub 2008/04/26. doi: 10.1136/bmj.39489.470347.AD 18436948; PubMed Central PMCID: PMC2335261.
152. Schunemann HJ, Oxman AD, Brozek J, Glasziou P, Bossuyt P, Chang S, et al. GRADE: assessing the quality of evidence for diagnostic recommendations. Evid Based Med. 2008;13(6):162–3. Epub 2008/12/02. doi: 10.1136/ebm.13.6.162-a 19043023.
153. Flemming K, Booth A, Garside R, Tuncalp O, Noyes J. Qualitative evidence synthesis for complex interventions and guideline development: clarification of the purpose, designs and relevant methods. BMJ Glob Health. 2019;4(Suppl 1):e000882. Epub 2019/02/19. doi: 10.1136/bmjgh-2018-000882 30775015; PubMed Central PMCID: PMC6350756.
154. Higgins JPT, Lopez-Lopez JA, Becker BJ, Davies SR, Dawson S, Grimshaw JM, et al. Synthesising quantitative evidence in systematic reviews of complex health interventions. BMJ Glob Health. 2019;4(Suppl 1):e000858. Epub 2019/02/19. doi: 10.1136/bmjgh-2018-000858 30775014; PubMed Central PMCID: PMC6350707.
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Najčítanejšie v tomto čísle- Psychometric validation of Czech version of the Sport Motivation Scale
- Comparison of Monocyte Distribution Width (MDW) and Procalcitonin for early recognition of sepsis
- Effects of supplemental creatine and guanidinoacetic acid on spatial memory and the brain of weaned Yucatan miniature pigs
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