#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#
preLekára.sk / Odborné časopisy / PLOS Pathogens / 2014 - 5

Are We There Yet? The Smallpox Research Agenda Using Variola Virus

English version České info

article has not abstract

Vyšlo v časopise: Are We There Yet? The Smallpox Research Agenda Using Variola Virus. PLoS Pathog 10(5): e32767. doi:10.1371/journal.ppat.1004108
Kategorie: Opinion
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.ppat.1004108

Souhrn

article has not abstract

Zdroje

1. Institute of Medicine (2009) Live Variola Virus: Considerations for Continuing Research. Washington (D.C.): The National Academies Press. Available: http://www.iom.edu/Reports/2009/LiveVariolaVirusContinuingResearch.aspx. Accessed: 26 March 2014.

2. WHO (2010) Scientific review of variola virus research, 1999–2010. Available: http://www.who.int/csr/disease/smallpox/major_review/en/. Accessed: 26 March 2014

3. ReedKD, MelskiJW, GrahamMB, RegneryRL, SotirMJ, et al. (2004) The detection of monkeypox in humans in the Western Hemisphere. N Engl J Med 350 : 342–350.

4. LiY, OlsonVA, LaueT, LakerMT, DamonIK (2006) Detection of monkeypox virus with real-time PCR assays. J Clin Virol 36 : 194–203.

5. Quixabeira-SantosJC, MedagliaML, PescadorCA, DamasoCR (2011) Animal movement and establishment of vaccinia virus cantagalo strain in Amazon biome, Brazil. Emerg Infect Dis 17 : 726–729.

6. DabrowskiPW, RadonicA, KurthA, NitscheA (2013) Genome-wide comparison of cowpox viruses reveals a new clade related to variola virus. PLoS One 8: e79953.

7. MoussatcheN, DamasoCR, McFaddenG (2008) When good vaccines go wild: Feral Orthopoxvirus in developing countries and beyond. J Infect Dev Ctries 2 : 156–173.

8. PrichardMN, KernER (2012) Orthopoxvirus targets for the development of new antiviral agents. Antiviral Res 94 : 111–125.

9. YangG, PevearDC, DaviesMH, CollettMS, BaileyT, et al. (2005) An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus Challenge. J Virol 79 : 13139–13149.

10. ParkerS, TouchetteE, OberleC, AlmondM, RobertsonA, et al. (2008) Efficacy of therapeutic intervention with an oral ether-lipid analogue of cidofovir (CMX001) in a lethal mousepox model. Antiviral Res 77 : 39–49.

11. MuckerEM, GoffAJ, ShamblinJD, GrosenbachDW, DamonIK, et al. (2013) Efficacy of tecovirimat (ST-246) in nonhuman primates infected with variola virus (Smallpox). Antimicrob Agents Chemother 57 : 6246–6253.

12. VoraS, DamonI, FulginitiV, WeberSG, KahanaM, et al. (2008) Severe eczema vaccinatum in a household contact of a smallpox vaccinee. Clin Infect Dis 46 : 1555–1561.

13. LedermanER, DavidsonW, GroffHL, SmithSK, WarkentienT, et al. (2012) Progressive vaccinia: case description and laboratory-guided therapy with vaccinia immune globulin, ST-246, and CMX001. J Infect Dis 206 : 1372–1385.

14. KretzschmarM, WallingaJ, TeunisP, XingS, MikolajczykR (2006) Frequency of adverse events after vaccination with different vaccinia strains. PLoS Med 3: e272.

15. MonathTP, CaldwellJR, MundtW, FuscoJ, JohnsonCS, et al. (2004) ACAM2000 clonal Vero cell culture vaccinia virus (New York City Board of Health strain)–a second-generation smallpox vaccine for biological defense. Int J Infect Dis 8 Suppl 2: S31–44.

16. KennedyJS, GurwithM, DekkerCL, FreySE, EdwardsKM, et al. (2011) Safety and immunogenicity of LC16m8, an attenuated smallpox vaccine in vaccinia-naive adults. J Infect Dis 204 : 1395–1402.

17. GreenbergRN, OvertonET, HaasDW, FrankI, GoldmanM, et al. (2013) Safety, immunogenicity, and surrogate markers of clinical efficacy for modified vaccinia Ankara as a smallpox vaccine in HIV-infected subjects. J Infect Dis 207 : 749–758.

18. FreySE, WinokurPL, SalataRA, El-KamarySS, TurleyCB, et al. (2013) Safety and immunogenicity of IMVAMUNE(R) smallpox vaccine using different strategies for a post event scenario. Vaccine 31 : 3025–3033.

19. KennedyRB, OvsyannikovaI, PolandGA (2009) Smallpox vaccines for biodefense. Vaccine 27 Suppl 4: D73–79.

20. DamonIK, DavidsonWB, HughesCM, OlsonVA, SmithSK, et al. (2009) Evaluation of smallpox vaccines using variola neutralization. J Gen Virol 90 : 1962–1966.

21. ShchelkunovSN (2013) An increasing danger of zoonotic orthopoxvirus infections. PLoS Pathog 9: e1003756.

22. SmeeDF, SidwellRW, KefauverD, BrayM, HugginsJW (2002) Characterization of wild-type and cidofovir-resistant strains of camelpox, cowpox, monkeypox, and vaccinia viruses. Antimicrob Agents Chemother 46 : 1329–1335.

23. SmeeDF, WanderseeMK, BaileyKW, HostetlerKY, HolyA, et al. (2005) Characterization and treatment of cidofovir-resistant vaccinia (WR strain) virus infections in cell culture and in mice. Antivir Chem Chemother 16 : 203–211.

24. JacksonRJ, RamsayAJ, ChristensenCD, BeatonS, HallDF, et al. (2001) Expression of mouse interleukin-4 by a recombinant ectromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox. J Virol 75 : 1205–1210.

25. McFaddenG (2010) Killing a killer: what next for smallpox? PLoS Pathog 6: e1000727.

26. CannJA, JahrlingPB, HensleyLE, Wahl-JensenV (2013) Comparative pathology of smallpox and monkeypox in man and macaques. J Comp Pathol 148 : 6–21.

Štítky
Hygiena a epidemiológia Infekčné lekárstvo Laboratórium
Článek Surveillance for Emerging Biodiversity Diseases of Wildlife
Článek The Emerging Role of Urease as a General Microbial Virulence Factor
Článek PARV4: An Emerging Tetraparvovirus
Článek Epigenetic Changes Modulate Schistosome Egg Formation and Are a Novel Target for Reducing Transmission of Schistosomiasis
Článek The Human Adenovirus E4-ORF1 Protein Subverts Discs Large 1 to Mediate Membrane Recruitment and Dysregulation of Phosphatidylinositol 3-Kinase
Článek A Multifactorial Role for Malaria in Endemic Burkitt's Lymphoma Pathogenesis
Článek Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease
Článek Cathepsin-L Can Resist Lysis by Human Serum in
Článek Epstein-Barr Virus Down-Regulates Tumor Suppressor Expression
Článek BCA2/Rabring7 Targets HIV-1 Gag for Lysosomal Degradation in a Tetherin-Independent Manner
Článek The Evolutionarily Conserved Mediator Subunit MDT-15/MED15 Links Protective Innate Immune Responses and Xenobiotic Detoxification
Článek Suppressor of Cytokine Signaling 4 (SOCS4) Protects against Severe Cytokine Storm and Enhances Viral Clearance during Influenza Infection
Článek T Cell Inactivation by Poxviral B22 Family Proteins Increases Viral Virulence
Článek Dynamics of HIV Latency and Reactivation in a Primary CD4+ T Cell Model
Článek HIV and HCV Activate the Inflammasome in Monocytes and Macrophages via Endosomal Toll-Like Receptors without Induction of Type 1 Interferon
Článek Virus and Autoantigen-Specific CD4+ T Cells Are Key Effectors in a SCID Mouse Model of EBV-Associated Post-Transplant Lymphoproliferative Disorders
Článek Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis
Článek Squalene Synthase As a Target for Chagas Disease Therapeutics
Článek The Contribution of Viral Genotype to Plasma Viral Set-Point in HIV Infection
Článek Combined Systems Approaches Reveal Highly Plastic Responses to Antimicrobial Peptide Challenge in
Článek Anthrax Lethal Factor as an Immune Target in Humans and Transgenic Mice and the Impact of HLA Polymorphism on CD4 T Cell Immunity
Článek Ly49C-Dependent Control of MCMV Infection by NK Cells Is -Regulated by MHC Class I Molecules
Článek Two Novel Human Cytomegalovirus NK Cell Evasion Functions Target MICA for Lysosomal Degradation
Článek A Large Family of Antivirulence Regulators Modulates the Effects of Transcriptional Activators in Gram-negative Pathogenic Bacteria
Článek Broad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response
Článek Malaria Parasite Infection Compromises Control of Concurrent Systemic Non-typhoidal Infection via IL-10-Mediated Alteration of Myeloid Cell Function
Článek A Role for in Higher Order Structure and Complement Binding of the Capsule
Článek Hip1 Modulates Macrophage Responses through Proteolysis of GroEL2
Článek CD8 T Cells from a Novel T Cell Receptor Transgenic Mouse Induce Liver-Stage Immunity That Can Be Boosted by Blood-Stage Infection in Rodent Malaria
Článek Phosphorylation of KasB Regulates Virulence and Acid-Fastness in
Článek HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality
Článek A Novel Mechanism Inducing Genome Instability in Kaposi's Sarcoma-Associated Herpesvirus Infected Cells
Článek Structural and Biochemical Characterization Reveals LysGH15 as an Unprecedented “EF-Hand-Like” Calcium-Binding Phage Lysin
Článek Hepatitis C Virus Cell-Cell Transmission and Resistance to Direct-Acting Antiviral Agents
Článek Different Modes of Retrovirus Restriction by Human APOBEC3A and APOBEC3G
Článek TNFα and IFNγ but Not Perforin Are Critical for CD8 T Cell-Mediated Protection against Pulmonary Infection
Článek Large Scale RNAi Reveals the Requirement of Nuclear Envelope Breakdown for Nuclear Import of Human Papillomaviruses
Článek The Cytoplasmic Domain of Varicella-Zoster Virus Glycoprotein H Regulates Syncytia Formation and Skin Pathogenesis
Článek A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase
Článek High-Efficiency Targeted Editing of Large Viral Genomes by RNA-Guided Nucleases
Článek Dynamic Functional Modulation of CD4 T Cell Recall Responses Is Dependent on the Inflammatory Environment of the Secondary Stimulus
Článek Bacterial Superantigens Promote Acute Nasopharyngeal Infection by in a Human MHC Class II-Dependent Manner
Článek Follicular Helper T Cells Promote Liver Pathology in Mice during Infection
Článek A Nasal Epithelial Receptor for WTA Governs Adhesion to Epithelial Cells and Modulates Nasal Colonization
Článek Unexpected Role for IL-17 in Protective Immunity against Hypervirulent HN878 Infection
Článek Human Cytomegalovirus Fcγ Binding Proteins gp34 and gp68 Antagonize Fcγ Receptors I, II and III
Článek Expansion of Murine Gammaherpesvirus Latently Infected B Cells Requires T Follicular Help
Článek Venus Kinase Receptors Control Reproduction in the Platyhelminth Parasite
Článek Molecular Signatures of Hemagglutinin Stem-Directed Heterosubtypic Human Neutralizing Antibodies against Influenza A Viruses
Článek The Downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 Axis and by Human Cytomegalovirus (HCMV) Associated Factors Allows the Activation of the HCMV Major IE Promoter and the Transition to Productive Infection
Článek Inactivation of Fructose-1,6-Bisphosphate Aldolase Prevents Optimal Co-catabolism of Glycolytic and Gluconeogenic Carbon Substrates in
Článek New Insights into Rotavirus Entry Machinery: Stabilization of Rotavirus Spike Conformation Is Independent of Trypsin Cleavage
Článek Prophenoloxidase Activation Is Required for Survival to Microbial Infections in
Článek SslE Elicits Functional Antibodies That Impair Mucinase Activity and Colonization by Both Intestinal and Extraintestinal Strains
Článek Timed Action of IL-27 Protects from Immunopathology while Preserving Defense in Influenza
Článek HIV-1 Envelope gp41 Broadly Neutralizing Antibodies: Hurdles for Vaccine Development
Článek The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in
Článek Cellular Superspreaders: An Epidemiological Perspective on HIV Infection inside the Body
Článek The Inflammasome Pyrin Contributes to Pertussis Toxin-Induced IL-1β Synthesis, Neutrophil Intravascular Crawling and Autoimmune Encephalomyelitis
Článek Papillomavirus Genomes Associate with BRD4 to Replicate at Fragile Sites in the Host Genome
Článek Integrative Functional Genomics of Hepatitis C Virus Infection Identifies Host Dependencies in Complete Viral Replication Cycle
Článek Co-assembly of Viral Envelope Glycoproteins Regulates Their Polarized Sorting in Neurons
Článek Targeting Membrane-Bound Viral RNA Synthesis Reveals Potent Inhibition of Diverse Coronaviruses Including the Middle East Respiratory Syndrome Virus
Článek Dual-Site Phosphorylation of the Control of Virulence Regulator Impacts Group A Streptococcal Global Gene Expression and Pathogenesis
Článok vyšiel v časopise

PLOS Pathogens

2014 Číslo 5
Najčítanejšie tento týždeň
Najčítanejšie v tomto čísle
Kurzy

Zvýšte si kvalifikáciu online z pohodlia domova

Citikolín v neuroprotekcii a neuroregenerácii – nové poznatky
nový kurz
Autori: MUDr. Petr Výborný, CSc., FEBO
Všetky kurzy
Prihlásenie
Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.

Prihlásenie

Nemáte účet?  Registrujte sa

#ADS_BOTTOM_SCRIPTS#