Morphological Mutations: Lessons from the Cockscomb

1. Wittkopp PJ, Kalay G (2012) Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergence. Nat Rev Genet 13 : 59–69. doi: 10.1038/nrg3095 22143240

2. Jones FC, Grabherr MG, Chan YF, Russell P, Mauceli E, et al. (2012) The genomic basis of adaptive evolution in threespine sticklebacks. Nature 484 : 55–61. doi: 10.1038/nature10944 22481358

3. Kratochwil CF, Meyer A (2015) Closing the genotype-phenotype gap: Emerging technologies for evolutionary genetics in ecological model vertebrate systems. Bioessays In press. doi: 10.1002/bies.201400142 25380076

4. Dorshorst B, Harun-Or-Rashid M, Bagherpoor AJ, Rubin CJ, Ashwell C, et al. (2015) A genomic duplication is associated with ectopic Eomesodermin expression in the embryonic chicken comb and two duplex-comb phenotypes. PLoS Genet 11(1): e1004947.

5. Bateson W (1902) Experiments with poultry. Rep Evol Comm Roy Soc 1 : 87–124.

6. Bateson W, Punnett RC (1905) A suggestion as to the nature of the "walnut" comb in fowls. Proc Camb Phil Soc 13 : 165–168.

7. Wright D, Boije H, Meadows JR, Bed'hom B, Gourichon D, et al. (2009) Copy number variation in intron 1 of SOX5 causes the Pea-comb phenotype in chickens. PLoS Genet 5: e1000512. doi: 10.1371/journal.pgen.1000512 19521496

8. Imsland F, Feng C, Boije H, Bed'hom B, Fillon V, et al. (2012) The Rose-comb mutation in chickens constitutes a structural rearrangement causing both altered comb morphology and defective sperm motility. PLoS Genet 8: e1002775. doi: 10.1371/journal.pgen.1002775 22761584

9. Boije H, Harun-Or-Rashid M, Lee YJ, Imsland F, Bruneau N, et al. (2012) Sonic Hedgehog-signalling patterns the developing chicken comb as revealed by exploration of the pea-comb mutation. PLoS One 7: e50890. doi: 10.1371/journal.pone.0050890 23227218

10. Somes RG (1991) Duplex comb in the chicken: a multi-allelic trait. J Hered 82 : 169–172. 2013691