#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Controlling Pre-leukemic Thymocyte Self-Renewal


article has not abstract


Vyšlo v časopise: Controlling Pre-leukemic Thymocyte Self-Renewal. PLoS Genet 10(12): e32767. doi:10.1371/journal.pgen.1004881
Kategorie: Perspective
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1004881

Souhrn

article has not abstract


Zdroje

1. Van VlierbergheP, FerrandoA (2012) The molecular basis of T cell acute lymphoblastic leukemia. J Clin Invest 122: 3398–3406.

2. TremblayCS, HoangT, HoangT (2010) Early T cell differentiation lessons from T cell acute lymphoblastic leukemia. Prog Mol Biol Transl Sci 92: 121–156.

3. PandolfiA, BarreyroL, SteidlU (2013) Concise review: preleukemic stem cells: molecular biology and clinical implications of the precursors to leukemia stem cells. Stem Cells Transl Med 2: 143–150.

4. Corces-Zimmerman MR, Majeti R (2014) Pre-leukemic evolution of hematopoietic stem cells: the importance of early mutations in leukemogenesis. Leukemia. E-pub ahead of print. doi:10.1038/leu.2014.211.

5. Corces-ZimmermanMR, HongWJ, WeissmanIL, MedeirosBC, MajetiR (2014) Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci U S A 111: 2548–2553.

6. ShlushLI, ZandiS, MitchellA, ChenWC, BrandweinJM, et al. (2014) Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia. Nature 506: 328–333.

7. TremblayCS, CurtisDJ (2014) The clonal evolution of leukemic stem cells in T cell acute lymphoblastic leukemia. Curr Opin Hematol 21: 320–325.

8. GerbyB, TremblayM, Rojas-SutterlinS, HébertJ, SauvageauG, et al. (2014) SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells. PLoS Genet 10: e1004768 doi:10.1371/journal.pgen.1004768

9. TremblayM, TremblayCS, HerblotS, AplanPD, HebertJ, et al. (2010) Modeling T cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes. Genes Dev 24: 1093–1105.

10. McCormackMP, ShieldsBJ, JacksonJT, NasaC, ShiW, et al. (2013) Requirement for Lyl1 in a model of Lmo2-driven early T cell precursor ALL. Blood 122: 2093–2103.

11. DelmoreJE, IssaGC, LemieuxME, RahlPB, ShiJ, et al. (2011) BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 146: 904–917.

12. HerblotS, SteffAM, HugoP, AplanPD, HoangT (2000) SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression. Nat Immunol 1: 138–144.

13. MatthewsJM, LesterK, JosephS, CurtisDJ (2013) LIM-domain-only proteins in cancer. Nat Rev Cancer 13: 111–122.

14. HayduJE, FerrandoAA (2013) Early T cell precursor acute lymphoblastic leukaemia. Curr Opin Hematol 20: 369–373.

Štítky
Genetika Reprodukčná medicína

Článok vyšiel v časopise

PLOS Genetics


2014 Číslo 12
Najčítanejšie tento týždeň
Najčítanejšie v tomto čísle
Kurzy

Zvýšte si kvalifikáciu online z pohodlia domova

Získaná hemofilie - Povědomí o nemoci a její diagnostika
nový kurz

Eozinofilní granulomatóza s polyangiitidou
Autori: doc. MUDr. Martina Doubková, Ph.D.

Všetky kurzy
Prihlásenie
Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.

Prihlásenie

Nemáte účet?  Registrujte sa

#ADS_BOTTOM_SCRIPTS#