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The Evolution of Sex Ratio Distorter Suppression Affects a 25 cM Genomic Region in the Butterfly

English version České info

The sex ratio of the offspring produced by an individual can be an evolutionary battleground. In many arthropod species, maternally inherited microbes selectively kill male hosts, and the host may in turn evolve strategies to restore the production or survival of males. When males are rare, the intensity of selection on the host may be extreme. We recently observed one such episode, in which the population sex ratio of the butterfly Hypolimnas bolina shifted from 100 females per male to near parity, through the evolution of a suppressor gene. In our current study, we investigate the hypothesis that the strength of selection in this case was so strong that the genomic impact would go well beyond the suppressor gene itself. After mapping the location of the suppressor within the genome of H. bolina, we examined changes in genetic variation at sites on the same chromosome as the suppressor. We show that a broad region of the genome was affected by the spread of the suppressor. Our data also suggest that the selection may have been sufficiently strong to introduce deleterious material into the population, which was later purged by selection.

Vyšlo v časopise: The Evolution of Sex Ratio Distorter Suppression Affects a 25 cM Genomic Region in the Butterfly. PLoS Genet 10(12): e32767. doi:10.1371/journal.pgen.1004822
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1004822

Souhrn

The sex ratio of the offspring produced by an individual can be an evolutionary battleground. In many arthropod species, maternally inherited microbes selectively kill male hosts, and the host may in turn evolve strategies to restore the production or survival of males. When males are rare, the intensity of selection on the host may be extreme. We recently observed one such episode, in which the population sex ratio of the butterfly Hypolimnas bolina shifted from 100 females per male to near parity, through the evolution of a suppressor gene. In our current study, we investigate the hypothesis that the strength of selection in this case was so strong that the genomic impact would go well beyond the suppressor gene itself. After mapping the location of the suppressor within the genome of H. bolina, we examined changes in genetic variation at sites on the same chromosome as the suppressor. We show that a broad region of the genome was affected by the spread of the suppressor. Our data also suggest that the selection may have been sufficiently strong to introduce deleterious material into the population, which was later purged by selection.

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2014 Číslo 12
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