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Respiratory Syncytial Virus Disease Is Mediated by Age-Variable IL-33


IL-33 is responsible for the immunopathophysiological response observed following neonatal RSV infection in mice. Its presence in nasal aspirates of human infants with severe RSV and suggests its role in disease severity and asthma.


Vyšlo v časopise: Respiratory Syncytial Virus Disease Is Mediated by Age-Variable IL-33. PLoS Pathog 11(10): e32767. doi:10.1371/journal.ppat.1005217
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.ppat.1005217

Souhrn

IL-33 is responsible for the immunopathophysiological response observed following neonatal RSV infection in mice. Its presence in nasal aspirates of human infants with severe RSV and suggests its role in disease severity and asthma.


Zdroje

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