Interferon-γ: The Jekyll and Hyde of Malaria

article has not abstract

Vyšlo v časopise: Interferon-γ: The Jekyll and Hyde of Malaria. PLoS Pathog 11(10): e32767. doi:10.1371/journal.ppat.1005118
Kategorie: Pearls
prolekare.web.journal.doi_sk: 10.1371/journal.ppat.1005118


article has not abstract


1. Miller JL, Sack BK, Baldwin M, Vaughan AM, Kappe SH. Interferon-mediated innate immune responses against malaria parasite liver stages. Cell Rep. 2014 Apr 4;7(2):436–47. doi: 10.1016/j.celrep.2014.03.018 24703850

2. De Souza JB, Williamson KH, Otani T, Playfair JH. Early gamma interferon responses in lethal and nonlethal murine blood-stage malaria. Infect Immun. 1997 May 4;65(5):1593–8. 9125535

3. Artavanis-Tsakonas K, Riley EM. Innate immune response to malaria: rapid induction of IFN-gamma from human NK cells by live Plasmodium falciparum-infected erythrocytes. J Immunol. 2002 Sep;169(6):2956–63. 12218109

4. Hviid L, Kurtzhals JA, Adabayeri V, Loizon S, Kemp K, Goka BQ, et al. Perturbation and proinflammatory type activation of V delta 1(+) gamma delta T cells in African children with Plasmodium falciparum malaria. Infect Immun. 2001 May 2;69(5):3190–6. 11292740

5. Pied S, Roland J, Louise A, Voegtle D, Soulard V, Mazier D, et al. Liver CD4-CD8- NK1.1+ TCR alpha beta intermediate cells increase during experimental malaria infection and are able to exhibit inhibitory activity against the parasite liver stage in vitro. J Immunol. 2000 Feb 2;164(3):1463–9. 10640763

6. Villegas-Mendez A, Greig R, Shaw TN, de Souza JB, Gwyer Findlay E, Stumhofer JS, et al. IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain. J Immunol. 2012 Jul;189(2):968–79. doi: 10.4049/jimmunol.1200688 22723523

7. Connelly M, King CL, Bucci K, Walters S, Genton B, Alpers MP, et al. T-cell immunity to peptide epitopes of liver-stage antigen 1 in an area of Papua New Guinea in which malaria is holoendemic. Infect Immun. 1997 Dec 1;65(12):5082–7. 9393799

8. Walther M, Jeffries D, Finney OC, Njie M, Ebonyi A, Deininger S, et al. Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria. PLoS Pathog. 2009 Apr 3;5(4):e1000364. doi: 10.1371/journal.ppat.1000364 19343213

9. Ong’echa JM, Lal AA, Terlouw DJ, Ter Kuile FO, Kariuki SK, Udhayakumar V, et al. Association of interferon-gamma responses to pre-erythrocytic stage vaccine candidate antigens of Plasmodium falciparum in young Kenyan children with improved hemoglobin levels: XV. Asembo Bay Cohort Project. Am J Trop Med Hyg. 2003 May 4;68(5):590–7. 12812352

10. Jagannathan P, Eccles-James I, Bowen K, Nankya F, Auma A, Wamala S, et al. IFNγ/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children. PLoS Pathog. 2014 Jan 3;10(1):e1003864. doi: 10.1371/journal.ppat.1003864 24415936

11. Freitas do Rosário AP, Lamb T, Spence P, Stephens R, Lang A, Roers A, et al. IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection. J Immunol. 2012 Feb 3;188(3):1178–90. doi: 10.4049/jimmunol.1102755 22205023

12. Couper KN, Blount DG, Wilson MS, Hafalla JC, Belkaid Y, Kamanaka M, et al. IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection. PLoS Pathog. 2008 Feb 5;4(2):e1000004. doi: 10.1371/journal.ppat.1000004 18401464

13. D’Ombrain MC, Robinson LJ, Stanisic DI, Taraika J, Bernard N, Michon P, et al. Association of early interferon-gamma production with immunity to clinical malaria: a longitudinal study among Papua New Guinean children. Clin Infect Dis. 2008 Dec 1;47(11):1380–7. doi: 10.1086/592971 18947328

14. Mitchell AJ, Hansen AM, Hee L, Ball HJ, Potter SM, Walker JC, et al. Early cytokine production is associated with protection from murine cerebral malaria. Infect Immun. 2005 Sep 4;73(9):5645–53. 16113282

15. Prakash D, Fesel C, Jain R, Cazenave P-AA, Mishra GC, Pied S. Clusters of cytokines determine malaria severity in Plasmodium falciparum-infected patients from endemic areas of Central India. J Infect Dis. 2006 Jul 6;194(2):198–207. 16779726

16. Pombo DJ, Lawrence G, Hirunpetcharat C, Rzepczyk C, Bryden M, Cloonan N, et al. Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum. Lancet. 2002 Aug 6;360(9333):610–7. 12241933

17. McCall MBB, Hopman J, Daou M, Maiga B, Dara V, Ploemen I, et al. Early interferon-gamma response against Plasmodium falciparum correlates with interethnic differences in susceptibility to parasitemia between sympatric Fulani and Dogon in Mali. J Infect Dis. 2010 Jan 5;201(1):142–52. doi: 10.1086/648596 19929378

18. Van der Heyde HC, Pepper B, Batchelder J, Cigel F, Weidanz WP. The time course of selected malarial infections in cytokine-deficient mice. Exp Parasitol. 1997 Feb 6;85(2):206–13. 9030670

19. Tsuji M, Mombaerts P, Lefrancois L, Nussenzweig RS, Zavala F, Tonegawa S. Gamma delta T cells contribute to immunity against the liver stages of malaria in alpha beta T-cell-deficient mice. Proc Natl Acad Sci USA. 1994 Jan 2;91(1):345–9. 8278391

20. Waddell SJ, Popper SJ, Rubins KH, Griffiths MJ, Brown PO, Levin M, et al. Dissecting interferon-induced transcriptional programs in human peripheral blood cells. PLoS ONE. 2010 Jan 5;5(3):e9753. doi: 10.1371/journal.pone.0009753 20339534

21. Xu W, Zhang JJ. Stat1-dependent synergistic activation of T-bet for IgG2a production during early stage of B cell activation. J Immunol. 2005 Dec 4;175(11):7419–24. 16301649

22. Doolan DL, Sedegah M, Hedstrom RC, Hobart P, Charoenvit Y, Hoffman SL. Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity. J Exp Med. 1996 Apr 1;183(4):1739–46. 8666931

23. Imai T, Shen J, Chou B, Duan X, Tu L, Tetsutani K, et al. Involvement of CD8+ T cells in protective immunity against murine blood-stage infection with Plasmodium yoelii 17XL strain. Eur J Immunol. 2010 Apr 4;40(4):1053–61. doi: 10.1002/eji.200939525 20101613

24. Su Z, Stevenson MM. Central role of endogenous gamma interferon in protective immunity against blood-stage Plasmodium chabaudi AS infection. Infect Immun. 2000 Aug 2;68(8):4399–406. 10899836

25. Su Z, Fortin A, Gros P, Stevenson MM. Opsonin-independent phagocytosis: an effector mechanism against acute blood-stage Plasmodium chabaudi AS infection. J Infect Dis. 2002 Nov 5;186(9):1321–9. 12402202

26. Amani V, Vigário AM, Belnoue E, Marussig M, Fonseca L, Mazier D, et al. Involvement of IFN-gamma receptor-medicated signaling in pathology and anti-malarial immunity induced by Plasmodium berghei infection. Eur J Immunol. 2000 Jun 4;30(6):1646–55. 10898501

27. Howland SW, Poh CM, Gun SY, Claser C, Malleret B, Shastri N, et al. Brain microvessel cross-presentation is a hallmark of experimental cerebral malaria. EMBO Mol Med. 2013 Jul 1;5(7):916–31. doi: 10.1002/emmm.201202273 23681698

28. Belnoue E, Potter SM, Rosa DS, Mauduit M, Grüner AC, Kayibanda M, et al. Control of pathogenic CD8+ T cell migration to the brain by IFN-gamma during experimental cerebral malaria. Parasite Immunol. 2008 Oct 3;30(10):544–53. doi: 10.1111/j.1365-3024.2008.01053.x 18665903

29. Haque A, Best SE, Unosson K, Amante FH, de Labastida F, Anstey NM, et al. Granzyme B expression by CD8+ T cells is required for the development of experimental cerebral malaria. J Immunol [Internet]. 2011 Jun 3;186(11):6148–56.

30. McCall MBB, Sauerwein RW. Interferon-γ—central mediator of protective immune responses against the pre-erythrocytic and blood stage of malaria. J Leukoc Biol. 2010 Dec 3;88(6):1131–43. doi: 10.1189/jlb.0310137 20610802

31. Freitas do Rosário AP, Muxel SM, Rodríguez-Málaga SMM, Sardinha LR, Zago CAA, Castillo-Méndez SI, et al. Gradual decline in malaria-specific memory T cell responses leads to failure to maintain long-term protective immunity to Plasmodium chabaudi AS despite persistence of B cell memory and circulating antibody. J Immunol. 2008 Dec 1;181(12):8344–55. 19050251

32. Da Silva HB, de Salles EM, Panatieri RH, Boscardin SB, Rodríguez-Málaga SMM, Alvarez JMM, et al. IFN-γ-induced priming maintains long-term strain-transcending immunity against blood-stage Plasmodium chabaudi malaria. J Immunol. 2013 Nov 5;191(10):5160–9. doi: 10.4049/jimmunol.1300462 24133169

Hygiena a epidemiológia Infekčné lekárstvo Laboratórium

Článok vyšiel v časopise

PLOS Pathogens

2015 Číslo 10
Najčítanejšie tento týždeň
Najčítanejšie v tomto čísle
Zabudnuté heslo

Nemáte účet?  Registrujte sa

Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.


Nemáte účet?  Registrujte sa