Abiotic Stresses Antagonize the Rice Defence Pathway through the Tyrosine-Dephosphorylation of OsMPK6

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Chemical defence inducers make plants resistant to diseases such as rice blast. However, plants sometimes become more pathogen susceptible under abiotic stresses even in their presence. Because such regulation prioritizes the responses to the most life-threatening stress, it could be necessary for plants to survive in nature. However, it seems dispensable or even disadvantageous for crops cultivated under fertile conditions. Here, we show the molecular mechanism underlying one of such phenomena in rice. WRKY45 is a central transcription factor that regulates strong defence signalling mediated by salicylic acid. We found that WRKY45 is activated through phosphorylation by a protein kinase, OsMPK6, which is activated by dual phosphorylation in response to the defence signalling. We also found that OsMPK6 can be inactivated by tyrosine dephosphorylation in response to abiotic stresses such as low temperature and high salinity probably mediated by abscisic acid, leading to reduction of WRKY45-dependent disease resistance. Moreover, we found that specific tyrosine protein phosphatases dephosphorylate/inactivate OsMPK6 in response to abiotic stresses. Knockdown of their genes rendered rice plants resistant against blast disease even under the abiotic stresses, pointing to the way to further improve rice.

Vyšlo v časopise: Abiotic Stresses Antagonize the Rice Defence Pathway through the Tyrosine-Dephosphorylation of OsMPK6. PLoS Pathog 11(10): e32767. doi:10.1371/journal.ppat.1005231
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.ppat.1005231

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