1. AhmadS (2011) Pathogenesis, immunology, and diagnosis of latent Mycobacterium tuberculosis infection. Clin Dev Immunol 2011: 814943.
2. SiaIG, WielandML (2011) Current concepts in the management of tuberculosis. Mayo Clin Proc 86: 348–361.
3. El BaghdadiJ, GrantAV, SabriA, El AzbaouiS, ZaidiH, et al. (2013) [Human genetics of tuberculosis]. Pathol Biol (Paris) 61: 11–16.
4. CottleLE (2011) Mendelian susceptibility to mycobacterial disease. Clin Genet 79: 17–22.
5. MischEA, MacdonaldM, RanjitC, SapkotaBR, WellsRD, et al. (2008) Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction. PLoS Negl Trop Dis 2: e231.
6. CawsM, ThwaitesG, DunstanS, HawnTR, LanNT, et al. (2008) The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis. PLoS Pathog 4: e1000034.
7. ThuongNT, HawnTR, ThwaitesGE, ChauTT, LanNT, et al. (2007) A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis. Genes Immun 8: 422–428.
8. TobinDM, VaryJCJr, RayJP, WalshGS, DunstanSJ, et al. (2010) The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. Cell 140: 717–730.
9. ZhangG, ChenX, ChanL, ZhangM, ZhuB, et al. (2011) An SNP selection strategy identified IL-22 associating with susceptibility to tuberculosis in Chinese. Sci Rep 1: 20.
10. ZhangG, ZhouB, WangW, ZhangM, ZhaoY, et al. (2012) A functional single-nucleotide polymorphism in the promoter of the gene encoding interleukin 6 is associated with susceptibility to tuberculosis. J Infect Dis 205: 1697–1704.
11. HayashiF, WatanabeM, NanbaT, InoueN, AkamizuT, et al. (2009) Association of the -31C/T functional polymorphism in the interleukin-1beta gene with the intractability of Graves' disease and the proportion of T helper type 17 cells. Clin Exp Immunol 158: 281–286.
12. LiC, WangC (2013) Current evidences on IL1B polymorphisms and lung cancer susceptibility: a meta-analysis. Tumour Biol 34: 3477–3482.
13. ChenML, LiaoN, ZhaoH, HuangJ, XieZF (2014) Association between the IL1B (−511), IL1B (+3954), IL1RN (VNTR) polymorphisms and Graves' disease risk: a meta-analysis of 11 case-control studies. PLoS One 9: e86077.
14. El-OmarEM, CarringtonM, ChowWH, McCollKE, BreamJH, et al. (2000) Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 404: 398–402.
15. MishraBB, RathinamVA, MartensGW, MartinotAJ, KornfeldH, et al. (2013) Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1beta. Nat Immunol 14: 52–60.
16. AwomoyiAA, CharuratM, MarchantA, MillerEN, BlackwellJM, et al. (2005) Polymorphism in IL1B: IL1B-511 association with tuberculosis and decreased lipopolysaccharide-induced IL-1beta in IFN-gamma primed ex-vivo whole blood assay. J Endotoxin Res 11: 281–286.
17. KusuharaK, YamamotoK, OkadaK, MizunoY, HaraT (2007) Association of IL12RB1 polymorphisms with susceptibility to and severity of tuberculosis in Japanese: a gene-based association analysis of 21 candidate genes. Int J Immunogenet 34: 35–44.
18. NaslednikovaIO, UrazovaOI, VoronkovaOV, StrelisAK, NovitskyVV, et al. (2009) Allelic polymorphism of cytokine genes during pulmonary tuberculosis. Bull Exp Biol Med 148: 175–180.
19. SunH, WangY, MaX, PeiF, ZhangY, et al. (2007) A method of oligochip for single nucleotide polymorphism genotyping in the promoter region of the interleukin-1 beta gene and its clinical application. Oligonucleotides 17: 336–344.
20. GomezLM, CamargoJF, CastiblancoJ, Ruiz-NarvaezEA, CadenaJ, et al. (2006) Analysis of IL1B, TAP1, TAP2 and IKBL polymorphisms on susceptibility to tuberculosis. Tissue Antigens 67: 290–296.
21. MishraBB, RathinamVA, MartensGW, MartinotAJ, KornfeldH, et al. (2012) Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1beta. Nat Immunol 14: 52–60.
22. DorhoiA, DeselC, YeremeevV, PradlL, BrinkmannV, et al. (2010) The adaptor molecule CARD9 is essential for tuberculosis control. J Exp Med 207: 777–792.
23. DorhoiA, IannacconeM, FarinacciM, FaeKC, SchreiberJ, et al. (2013) MicroRNA-223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment. J Clin Invest.
24. GabayC, LamacchiaC, PalmerG (2010) IL-1 pathways in inflammation and human diseases. Nat Rev Rheumatol 6: 232–241.
25. JuffermansNP, FlorquinS, CamoglioL, VerbonA, KolkAH, et al. (2000) Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis. J Infect Dis 182: 902–908.
26. YamadaH, MizumoS, HoraiR, IwakuraY, SugawaraI (2000) Protective role of interleukin-1 in mycobacterial infection in IL-1 alpha/beta double-knockout mice. Lab Invest 80: 759–767.
27. O'KaneCM, ElkingtonPT, JonesMD, CaviedesL, TovarM, et al. (2010) STAT3, p38 MAPK, and NF-kappaB drive unopposed monocyte-dependent fibroblast MMP-1 secretion in tuberculosis. Am J Respir Cell Mol Biol 43: 465–474.
28. HarrisJE, Fernandez-VilasecaM, ElkingtonPT, HorncastleDE, GraeberMB, et al. (2007) IFNgamma synergizes with IL-1beta to up-regulate MMP-9 secretion in a cellular model of central nervous system tuberculosis. Faseb J 21: 356–365.
29. LyadovaIV, TsiganovEN, KapinaMA, ShepelkovaGS, SosunovVV, et al. (2010) In mice, tuberculosis progression is associated with intensive inflammatory response and the accumulation of Gr-1 cells in the lungs. PLoS One 5: e10469.
30. ChensueSW, DaveyMP, RemickDG, KunkelSL (1986) Release of interleukin-1 by peripheral blood mononuclear cells in patients with tuberculosis and active inflammation. Infect Immun 52: 341–343.
31. TsaoTC, LiL, HsiehM, LiaoS, ChangKS (1999) Soluble TNF-alpha receptor and IL-1 receptor antagonist elevation in BAL in active pulmonary TB. Eur Respir J 14: 490–495.
32. HarrisonP, PointonJJ, ChapmanK, RoddamA, WordsworthBP (2008) Interleukin-1 promoter region polymorphism role in rheumatoid arthritis: a meta-analysis of IL-1B-511A/G variant reveals association with rheumatoid arthritis. Rheumatology (Oxford) 47: 1768–1770.
33. MigitaK, MaedaY, AbiruS, NakamuraM, KomoriA, et al. (2007) Polymorphisms of interleukin-1beta in Japanese patients with hepatitis B virus infection. J Hepatol 46: 381–386.
34. Martinez-CarrilloDN, Garza-GonzalezE, Betancourt-LinaresR, Monico-ManzanoT, Antunez-RiveraC, et al. (2010) Association of IL1B -511C/-31T haplotype and Helicobacter pylori vacA genotypes with gastric ulcer and chronic gastritis. BMC Gastroenterol 10: 126.
35. SunH, WangY, MaX, PeiF, SunH, et al. (2007) A method of oligochip for single nucleotide polymorphism genotyping in the promoter region of the interleukin-1 beta gene and its clinical application. Oligonucleotides 17: 336–344.
36. QiuZ, ZhangM, ZhuY, ZhengF, LuP, et al. (2012) Multifunctional CD4 T cell responses in patients with active tuberculosis. Sci Rep 2: 216.
37. OrsF, DenizO, BozlarU, GumusS, TasarM, et al. (2007) High-resolution CT findings in patients with pulmonary tuberculosis: correlation with the degree of smear positivity. J Thorac Imaging 22: 154–159.
38. WenAQ, WangJ, FengK, ZhuPF, WangZG, et al. (2006) Effects of haplotypes in the interleukin 1beta promoter on lipopolysaccharide-induced interleukin 1beta expression. Shock 26: 25–30.
39. ZielinskiCE, MeleF, AschenbrennerD, JarrossayD, RonchiF, et al. (2012) Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta. Nature 484: 514–518.
40. LasiglieD, TraggiaiE, FedericiS, AlessioM, BuoncompagniA, et al. (2012) Role of IL-1 beta in the development of human T(H)17 cells: lesson from NLPR3 mutated patients. PLoS One 6: e20014.
41. ChenX, YangQ, ZhangM, GranerM, ZhuX, et al. (2009) Diagnosis of active tuberculosis in China using an in-house gamma interferon enzyme-linked immunospot assay. Clin Vaccine Immunol 16: 879–884.
42. ZhangM, WangH, LiaoM, ChenX, GranerM, et al. (2010) Diagnosis of latent tuberculosis infection in bacille Calmette-Guerin vaccinated subjects in China by interferon-gamma ELISpot assay. Int J Tuberc Lung Dis 14: 1556–1563.
43. LindH, HaugenA, ZienolddinyS (2007) Differential binding of proteins to the IL1B -31 T/C polymorphism in lung epithelial cells. Cytokine 38: 43–48.
44. KominatoY, GalsonD, WatermanWR, WebbAC, AuronPE (1995) Monocyte expression of the human prointerleukin 1 beta gene (IL1B) is dependent on promoter sequences which bind the hematopoietic transcription factor Spi-1/PU.1. Mol Cell Biol 15: 58–68.
45. FremondCM, TogbeD, DozE, RoseS, VasseurV, et al. (2007) IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection. J Immunol 179: 1178–1189.
46. VerwayM, BouttierM, WangTT, CarrierM, CalderonM, et al. (2013) Vitamin D Induces Interleukin-1beta Expression: Paracrine Macrophage Epithelial Signaling Controls M. tuberculosis Infection. PLoS Pathog 9: e1003407.
47. BhowmickR, Tin MaungNH, HurleyBP, GhanemEB, GronertK, et al. (2013) Systemic Disease during Streptococcus pneumoniae Acute Lung Infection Requires 12-Lipoxygenase-Dependent Inflammation. J Immunol.
48. LitvakV, RatushnyAV, LampanoAE, SchmitzF, HuangAC, et al. (2012) A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses. Nature 490: 421–425.
49. CillonizC, ShinyaK, PengX, KorthMJ, ProllSC, et al. (2009) Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes. PLoS Pathog 5: e1000604.
50. TrajkovD, TrajchevskaM, ArsovT, PetlichkovskiA, StrezovaA, et al. (2009) Association of 22 cytokine gene polymorphisms with tuberculosis in Macedonians. Indian J Tuberc 56: 117–131.
51. Motsinger-ReifAA, AntasPR, OkiNO, LevyS, HollandSM, et al. (2010) Polymorphisms in IL-1beta, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis. BMC Med Genet 11: 37.
52. WilkinsonRJ, PatelP, LlewelynM, HirschCS, PasvolG, et al. (1999) Influence of polymorphism in the genes for the interleukin (IL)-1 receptor antagonist and IL-1beta on tuberculosis. J Exp Med 189: 1863–1874.
53. LiuY, LiS, ZhangG, NieG, MengZ, et al. (2013) Genetic variants in IL1A and IL1B contribute to the susceptibility to 2009 pandemic H1N1 influenza A virus. BMC Immunol 14: 37.
54. MikamiT, MeguroA, TeshigawaraT, TakeuchiM, UemotoR, et al. (2013) Interleukin 1 beta promoter polymorphism is associated with keratoconus in a Japanese population. Mol Vis 19: 845–851.
55. KimSH, MokJW, KimHS, JooCK (2008) Association of -31T>C and -511 C>T polymorphisms in the interleukin 1 beta (IL1B) promoter in Korean keratoconus patients. Mol Vis 14: 2109–2116.
56. RechcinskiT, GrebowskaA, KurpesaM, SztybrychM, PerugaJZ, et al. (2009) Interleukin-1b and interleukin-1 receptor inhibitor gene cluster polymorphisms in patients with coronary artery disease after percutaneous angioplasty or coronary artery bypass grafting. Kardiol Pol 67: 601–610.
57. LaiosaCV, StadtfeldM, XieH, de Andres-AguayoL, GrafT (2006) Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors. Immunity 25: 731–744.
58. MaoK, ChenS, ChenM, MaY, WangY, et al. (2013) Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock. Cell Res 23: 201–212.
59. GallegosAM, van HeijstJW, SamsteinM, SuX, PamerEG, et al. (2011) A gamma interferon independent mechanism of CD4 T cell mediated control of M. tuberculosis infection in vivo. PLoS Pathog 7: e1002052.
60. CaccamoN, GugginoG, JoostenSA, GelsominoG, Di CarloP, et al. (2010) Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection. Eur J Immunol 40: 2211–2220.
61. JuradoJO, PasquinelliV, AlvarezIB, PenaD, RovettaAI, et al. (2012) IL-17 and IFN-gamma expression in lymphocytes from patients with active tuberculosis correlates with the severity of the disease. J Leukoc Biol 91: 991–1002.
62. NandiB, BeharSM (2011) Regulation of neutrophils by interferon-gamma limits lung inflammation during tuberculosis infection. J Exp Med 208: 2251–2262.
63. KellerC, HoffmannR, LangR, BrandauS, HermannC, et al. (2006) Genetically determined susceptibility to tuberculosis in mice causally involves accelerated and enhanced recruitment of granulocytes. Infect Immun 74: 4295–4309.
64. EumSY, KongJH, HongMS, LeeYJ, KimJH, et al. (2010) Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB. Chest 137: 122–128.
65. HnizdoE, SinghT, ChurchyardG (2000) Chronic pulmonary function impairment caused by initial and recurrent pulmonary tuberculosis following treatment. Thorax 55: 32–38.
66. PengR, YueJ, HanM, ZhaoY, LiuL, et al. (2013) The IL-17F sequence variant is associated with susceptibility to tuberculosis. Gene 515: 229–232.
67. ChenX, ZhangM, LiaoM, GranerMW, WuC, et al. (2010) Reduced Th17 response in patients with tuberculosis correlates with IL-6R expression on CD4+ T Cells. Am J Respir Crit Care Med 181: 734–742.
68. ChenX, ZhouB, LiM, DengQ, WuX, et al. (2007) CD4(+)CD25(+)FoxP3(+) regulatory T cells suppress Mycobacterium tuberculosis immunity in patients with active disease. Clin Immunol 123: 50–59.
69. NovikovA, CardoneM, ThompsonR, ShenderovK, KirschmanKD, et al. (2011) Mycobacterium tuberculosis triggers host type I IFN signaling to regulate IL-1beta production in human macrophages. J Immunol 187: 2540–2547.
70. TodaY, TsukadaJ, MisagoM, KominatoY, AuronPE, et al. (2002) Autocrine induction of the human pro-IL-1beta gene promoter by IL-1beta in monocytes. J Immunol 168: 1984–1991.
71. YuLL, ChangK, LuLS, ZhaoD, HanJ, et al. (2013) Lentivirus-mediated RNA interference targeting the H19 gene inhibits cell proliferation and apoptosis in human choriocarcinoma cell line JAR. BMC Cell Biol 14: 26.