Educational and health outcomes associated with bronchopulmonary dysplasia in 15-year-olds born preterm

English version

Autoři: David Drummond ^aff001; Alice Hadchouel ^aff001; Heloise Torchin ^aff002; Jean-Christophe Rozé ^aff004; Catherine Arnaud ^aff006; Adèle Bellino ^aff009; Laure Couderc ^aff010; Stéphane Marret ^aff011; Marie Mittaine ^aff012; Didier Pinquier ^aff011; Marie Vestraete ^aff013; Jessica Rousseau ^aff014; Pierre-Yves Ancel ^aff002; Christophe Delacourt ^aff001;
Působiště autorů: Paediatric Pulmonology, University Hospital Necker-Enfants Malades, AP-HP, Paris, France ^aff001; Paris Descartes University, Paris, France ^aff002; Port Royal Hospital, AP-HP, Paris, France ^aff003; Department of Neonatal Medicine, Nantes University Hospital, Nantes, France ^aff004; CIC004, Nantes University Hospital, Nantes, France ^aff005; UMR1027, INSERM, Toulouse, France ^aff006; Paul Sabatier University, Toulouse, France ^aff007; Clinical Epidemiology Unit, CHU Purpan, Toulouse, France ^aff008; Clinical Research Unit Cochin-Necker, AP-HP, Paris, France ^aff009; Rouen University Hospital, Pediatric Pulmonology and Allergology, Inserm CIC-CRB 1404 Rouen, France ^aff010; INSERM U1245, Team 4, Perinatal Neurological Handicap and Brain Protection, IRIB, School of Medicine, Normandy University, Rouen, France and Department of Neonatal Medicine and Neuropediatrics, Rouen University Hospital, Rouen, France ^aff011; Paediatric Pulmonology and Allergology Department, CHU Purpan, Toulouse, France ^aff012; CRCM Enfants, University Hospital, Nantes, France ^aff013; Obstetrical, Perinatal, and Paediatric Epidemiology Team, Epidemiology and Biostatistics Sorbonne Paris Cité Research Centre (U1153), INSERM, Paris, France ^aff014; Clinical Research Unit, Centre for Clinical Investigation, P1419 Cochin Broca Hôtel-Dieu, APHP, Paris, France ^aff015
Vyšlo v časopise: PLoS ONE 14(9)
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pone.0222286

Souhrn

Introduction

To evaluate the consequences of bronchopulmonary dysplasia (BPD) on academic outcomes and healthcare use in adolescents born very preterm.

Methods

This cohort study included 15-year-old adolescents born very preterm (< 32 weeks) between 2011 and 2013, with and without BPD, and controls born full term. Data regarding academic performance, current medical follow-up, and family characteristics were collected. Multivariate logistic regression was used to quantify relationships between academic outcomes and BPD.

Results

From the 1341 children included in the initial cohort, 985 adolescents were eligible and 351 included (55 preterms with a history of BPD, 249 without, and 47 controls). Among adolescents born very preterm, a history of BPD was associated with a higher risk to attend a school for children with special needs (p < 0.05) and to have repeated a grade (p = 0.01). It was also associated with an increased number of medical and paramedical consultations. A history of BPD was not associated with the parents’ employment status, family structure, or the presence of younger siblings.

Conclusion

This study highlights that a history of BPD is associated with poorer academic outcomes and high healthcare use in adolescence.

Klíčová slova:

Biology and life sciences – Physical sciences – Chemistry – Social sciences – Sociology – People and places – Population groupings – Developmental biology – Medicine and health sciences – Chemical compounds – Pathology and laboratory medicine – Organic compounds – Organic chemistry – Neonates – Diagnostic medicine – Signs and symptoms – Education – Schools – Age groups – Children – Families – Vascular medicine – Steroids – Ethnicities – European people – Hemorrhage – Adolescents – French people – Dysplasia

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