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Manipulating the odds: The effects of Machiavellianism and construal level on cheating behavior
Authors: Mariela E. Jaffé aff001; Rainer Greifeneder aff001; Marc-André Reinhard aff002
Authors place of work: Center for Social Psychology, University of Basel, Basel, Switzerland aff001; Chair of Social Psychology, University of Kassel, Kassel, Germany aff002
Published in the journal: PLoS ONE 14(11)
Category: Research Article
doi: https://doi.org/10.1371/journal.pone.0224526Summary
Values, beliefs, and traits differ across individuals, and these concepts might impact whether individuals choose to engage in (dis)honest behavior. This project focuses on interindividual differences in Machiavellianism, which is defined as a tendency toward cynicism and manipulativeness, and the belief that the ends justify the means. We hypothesized that trait Machiavellianism would predict dishonest behavior. Furthermore, we speculated that some situations are more conducive than others for Machiavellianism to translate into behavior. In particular, Construal Level Theory holds that individuals construe social situations on a concrete level, or an abstract level, and that an abstract construal level triggers values and value-related traits to be more influential on behavior. Against this background, we hypothesized that differences in Machiavellianism produce differences in dishonest monetary behavior when situations are construed abstractly. Four studies tested these considerations by asking participants to toss a coin and self-report the toss’ outcome. Inconsistent with our theorizing, we did not find that higher Machiavellianism is consistently associated with a higher self-reported probability of receiving an individual bonus. We also did not find consistent support that higher Machiavellianism is associated with cheating under abstract compared to concrete construal.
Keywords:
Behavior – Regression analysis – Personality – Personality traits – Deception – Personality disorders – Payment – National security
Introduction
Dishonest, deceitful, and fraudulent behaviors may cause severe damage on the individual, group, and societal level [1,2]. In today’s world, there is no shortage of political and economic scandals, and many of these are characterized by persons in power abusing their opportunities to benefit themselves or a select group. A prominent example is the recent “Dieselgate” affair [3], where Volkswagen was accused of having intentionally programmed diesel engines to activate emission controls only during laboratory testing (the diesel engines therefore appeared “cleaner” than they actually were), which caused severe financial harm to customers and stakeholders, and negatively affected the environment in unknown dimensions. Dishonesty was also a major concern in the 2016 US election and in the 2016 BREXIT campaign, during which terms such as “alternative facts” or “post-truth” emerged and thrived. Given that honesty is one of the cardinal values in our society, this picture is rather puzzling. On the one hand, one may speculate that behavior is not guided by the value of honesty. On the other hand, it is possible that honesty is still guiding behavior, but that different, more egoistic values dominate the behavior of powerful politicians and managers. This project touches on both speculations by suggesting that dishonest behavior surfaces when egoistic cognitions are particularly strong and furthermore tests whether values and value-related traits may guide behavior under some circumstances more than others. More specifically, we suggest that a high level of Machiavellianism [4] may result in dishonest behavior. Furthermore, we speculate that this tendency is especially pronounced when the dishonest behavior is self-serving and when individuals have an abstract representation of the situation, which is particularly likely in conditions of power [5,6]. To delineate this hypothesis, we start our review of the literature by focusing on values of virtue and vice. Prior literature has treated Machiavellianism as a belief [7,8], closely related to social values [9], but most frequently as a personality trait [10]. While values and traits are distinct concepts, they share the common signature of intra-individually enduring influence. We emphasize this common signature, but generally opt for the term Machiavellian personality trait [11] in what follows, consistent with the majority of prior research. At the same time, when referring to specific prior contributions, we stick to their theoretical framework and terminology. Part of our reasoning is derived from the strong literature on values and here we build on using the respective terms.
Values of virtue and vice that guide behavior
Values are concepts that pertain to desirable behaviors and transcend specific situations. Values guide the selection or evaluation of behaviors [12], and predict a broad range of meaningful decisions and behaviors, e.g., [13,14]. Schwartz [15], for example, describes that value systems may be used to predict voting behavior in national elections, interpersonal cooperation, and readiness for social contact with outgroup members. One key model regarding values was established by Schwartz [12], who suggested 10 basic human values: universalism, self-direction, stimulation, hedonism, achievement, power, security, conformity, tradition, and benevolence. Per the definition, all values pertain to desirable end states [12], both on the individual and on the societal level. Schwartz’s values could therefore be considered as values of virtue. To illustrate one value in exemplary fashion, consider the value of security, which is driven by the motivational goal of safety, harmony, and stability of society, of relationships, and of the self [12]. Security values result in the pursuit of individual interests (e.g., by staying healthy), but also collective interests (e.g., protecting national security).
Next to these values of virtue, there are also more “negative” and “dark” values and personality traits, which reflect more egoistic motives that individuals might pursue. These traits pertain to less desirable end states, if not for the individual then on the societal level. Individuals, for example, differ with respect to Machiavellianism [4]. Machiavellianism is described as a “tendency toward Machiavellian behavior, in particular cynicism, a penchant for manipulativeness, and the belief that the end sanctifies the means” [16] (p. 54). Machiavellianism is generally measured as the extent to which respondents agree with statements taken from Machiavelli’s original books [4]. Some contributions refer to Machiavellianism as a belief, e.g., [7,8], which is closely related to social values such as moral flexibility and the devaluation of collective interests [9]. Other contributions consider Machiavellianism as one of the three personality traits of the Dark Triad, next to narcissism and psychopathy [10]. All three dark traits entail a socially malevolent character with behavior tendencies toward self-promotion, emotional coldness, duplicity, and aggressiveness [10]. Machiavellianism, for example, has been linked to active deception [17] and unethical behavior [18]. All dark traits are primarily linked to the pursuit of individual and not collective interests. Interestingly, recent research has also documented that Machiavellians also engage in prosocial behavior that benefits their organizations. The underlying reason for this, however, is to increase their chances of benefitting economically and professionally from their employer, which again is a selfish motive [19], see also [20].
The power of the situation: When do values guide behavior?
Values are intra-individually enduring concepts. Their impact, however, might depend on the specific social situation, as prior research has illustrated. For example, values have been shown to exert a stronger impact when individuals actually focus on their standards of behavior. Consider evidence reported by Beaman, Klentz, Diener, and Svanum [21], who placed a mirror behind a bowl of Halloween candy and asked children to take one piece only. The presence of a mirror led to decreased transgression rates in those children who mentioned their names and addresses before, in that they were less likely to take more than one piece of candy. The authors argue that the mirror increased individuals’ self-awareness, which renders a person more likely to focus on her/his standards of behavior. Similarly, Diener and Wallbom [22] showed that college students tended to cheat less on an intelligence test when they observed their reflection in a mirror. Providing further corroborating evidence, Mazar, Amir, and Ariely [23] showed that making moral standards more accessible through situational cues (e.g., by asking participants to either write down the Ten Commandments or books they had read in high school) made individuals behave more honestly. Kleinlogel, Dietz, and Antonakis [24] applied these findings to personality traits and showed that the factor Honesty-Humility, the tendency to be sincere, fair, and modest [25], predicted cheating behavior. Individuals low on Honesty-Humility cheated more when exposed to immoral (compared to moral) primes, while individuals high on Honesty-Humility were less affected by situational primes.
Findings such as these attest that situational cues influence whether values impact behavior. Situations can motivate individuals with a given tendency to act out on this tendency (“press”) [26]. To the extent that values are related to virtues, increasing their impact on behavior appears highly laudable. However, if values are related to vices, this strategy could also backfire. In particular, if the situational cues increase the salience of “dark” values, individuals might be more likely to manipulate and cheat.
How does construal level influence the impact of values on behavior?
Eyal, Sagristano, Trope, Liberman, and Chaiken [27] showed that values exerted a greater impact on how individuals plan their distant future than their near future. The researchers assessed participants’ values and asked them to read eleven vignettes of hypothetical situations that presented a behavior that was consistent with one of the values. When planning the distant future, values and behavioral intentions correlated more strongly, while this relation was attenuated when participants planned for the close future [27]. These findings were corroborated by Rixom and Mishra [28], who assumed that individuals generally value honesty, and therefore showed that participants who adopted an abstract construal level compared to a concrete construal level tended to behave more honestly. Reversely, in situations in which dishonesty served the greater good of another party, benevolence in the form of money given to charity was the value in focus, and participants who adopted an abstract construal level therefore tended to be behave less honestly. Presumably, here their behavior was driven by the value of benevolence, and more so under abstract than under concrete construal level. In both cases, participants’ behavior was impacted more strongly by their values when they were primed to adopt an abstract compared to concrete construal level.
These findings can be explained against the background of Construal Level Theory [29–31], which holds that individuals may construe social situations on a high-and-abstract level, or a more low-and-concrete level. Abstract representations contain the gist of situations, meaning superordinate and central information, as well as information on the desirability of situations. By definition, values are abstract and decontextualized, and are therefore hypothesized to serve as high-level behavioral guides [29]. In contrast, concrete representations contain more details and subordinate information, as well as more information regarding the feasibility of actions in situations. To illustrate this differentiation between abstract and concrete, consider a game of basketball [30]: An abstract representation of a game of basketball could be “having fun,” while a more concrete representation could include that the players are children of a certain age. Here, “the higher-level construal disregards the unique features of the event and entails an implicit decision about which features are central to the event and which are peripheral” [30].
The level of construal depends on psychological distance. Psychologically distant objects or events (in regards to time, space, social connection, or likelihood) are construed more abstractly, and psychologically close objects or events more concretely. A basketball game taking place a year from now (versus today) would be more likely to be construed abstractly (concretely). Reversely, because values are abstract and decontextualized, they are expected to be more readily applied to and guide intentions for psychologically distant situations [29], but see [32] for a replication that was only partially successful. Interestingly, because traits have been defined as “probabilistic descriptions of relatively stable patterns of emotion, motivation, cognition, and behavior” [33], they are also rather decontextualized concepts, so that traits may be similarly expected to more likely guide behavior when construal is abstract.
Dishonesty as a result of an abstract construal level and Machiavellianism
The following general considerations were derived against the background of Construal Level Theory: Individuals’ values and traits impact their (dis)honest behavior, and more so in conditions of abstract construal level. Importantly, if values and traits are related to virtues (e.g., fairness), individuals with high scores should be more likely to show honest behavior, particularly when construing abstractly. If values and traits relate to vices, however, individuals with high scores should be more likely to show dishonest behavior, again particularly when construing abstractly.
From these general considerations we derived the specific hypothesis that individuals with high compared to low scores on Machiavellianism are more likely to show dishonest behavior. We furthermore qualified this hypothesis by speculating that the relationship between Machiavellianism and dishonest behavior is particularly pronounced when construing abstractly. While this contribution focuses on Machiavellianism, one could argue that similar reasoning may relate to other values, beliefs, and personality traits, too, that are related to dishonest behavior such as narcissism, e.g., [10], belief in a just world [34], or belief in a competitive-jungle world [35]. We will later return to these considerations.
We tested our Machiavellianism hypotheses in four studies. The first one took an exploratory approach. Here we assessed a variety of constructs to measure values and traits. We then tested our hypothesis and analyzed whether values and traits explain dishonest behavior in general (Hypothesis 1) and more so in conditions of abstract compared to concrete construal (Hypothesis 2). The second study was of a confirmatory nature. Here, we focused on Machiavellianism and replicated the finding that individual differences in Machiavellianism explain honest versus dishonest behavior under abstract but not under concrete construal level. Study 3 and 4 were conducted to replicate the results from Study 2. Finally, data from Studies 2, 3, and 4 were pooled to conduct a raw data meta-analysis. An IRB Approval by the Institutional Review Board of the Faculty of Psychology from the University of Basel has been obtained for this research project. Participants’ consent has been obtained in a written manner throughout all studies.
Study 1
Study 1 explored the general notion that negatively connoted personality traits (e.g., Machiavellianism, narcissism, and others) impact behavior (i.e., cheating), and more so in conditions of abstract construal. To this end, we assessed individuals’ Machiavellianism scores as well as several other values, beliefs, and traits, which have proven to predict a multitude of different behaviors.
We included the 10 basic human values [12], given their predominance in the research field. Moreover, we included individuals’ belief in a just world. This belief is associated with reciprocal behavior, and we assumed that it could be related to honest behavior, because strong believers in a just world might fear the negative fate that would befall someone who cheats [36]. Furthermore, we assessed individuals belief in a just world [34], which refers to individuals’ belief that their environment is a just and orderly place where people usually get what they deserve [37]. Edlund, Sagarin, and Johnson [36], for example, have shown that belief in a just world is associated with reciprocal behavior. Individuals who were stronger in the belief in a just world engaged in more reciprocal behavior. Presumably, individuals then might also be less likely to engage in dishonest behavior.
We also included a set of personality traits that are more “dark” and potentially linked to more dishonest behavior. Machiavellianism and narcissism are both associated with tendencies towards self-promotion [10]. Whereas Machiavellianism is described as the belief that the end sanctifies the means [16], narcissism is associated with facets such as entitlement or dominance [10]. The association between both personality traits and dishonest behavior have been investigated, and findings indicate that Machiavellianism could be linked to the propensity to lie in different contexts [17,38,39]. We did not assess the complete Dark Triad. One reason not to include psychopathy is that psychopathy predicts a wider range of socially undesirable behavior beyond dishonesty.
We also assessed individuals’ belief in a competitive-jungle world, which is defined as the belief that “the social world is a competitive jungle characterized by a ruthless, amoral struggle for resources and power in which might is right and winning is everything” [35]. Some of the items clearly indicate that dishonesty might be an appropriate behavior (such as “You know that most people are out to “screw” you, so you have to get them first when you get the chance”), although this scale is more related to the study of prejudice, ethnocentrism, and intergroup hostility [35].
All variables included so far are likely predictive of (dis-)honest behavior. However, we also wished to test for discriminant validity and therefore included a measure that should not predict dishonest behavior. In doing so, we wished to demonstrate that our outcome measure is sensitive to variables related to cheating and would not display associations with variables that are unrelated to cheating behavior. Against this background, we elected to assess the personality trait extraversion as the last variable, as it is, to our knowledge, not associated with dishonest behavior, e.g., [40], but see [41] for findings that deviate from the results of the meta analysis.
All in all, Study 1 explored the research question of whether negatively connoted traits impact dishonest behavior, and whether they do so more in conditions of abstract compared to concrete construal. We relied upon a setting in which dishonest behavior increases the likelihood of gaining a bonus payment, either for the individual (self-serving) or for a charitable organization (other-serving). The self-serving versus other-serving variation was conceptually inspired by the work of Rixom and Mishra [28], who implemented a condition in which cheating would serve a “good” charitable organization compared to a “bad” charitable organization. These authors found that cheating increased under an abstract construal level when a “good” organization would profit, but decreased when a “bad” organization would profit. Against this background, it appeared fruitful to vary the beneficiaries of cheating, and we decided to do so by introducing a self-serving and an other-serving condition. We assumed that dark traits translate into dishonest behavior (and more so under abstract construal level), particularly if the dishonest behavior is self-serving. However, in a condition where other people would benefit, this association between Machiavellianism and dishonest behavior should be attenuated or eventually even reverse.
Method
Participants and design
Research within the area of Construal Level Theory indicates the occurrence of medium sizes [42]. With no knowledge of effect sizes focusing on the interplay between construal level and deceptive behavior, we decided to assess 40 participants for each between subjects cell (construal level and bonus recipient) as a rough approximation to achieve sufficient power, resulting in a minimum of 160 participants.
One hundred and sixty four US-American participants (Mage = 32.27 years, SD = 11.24) were recruited for a “Personality study” via prolific academic [43] and completed the study by reporting an outcome regarding the coin toss, which served as our main dependent variable, and were therefore included in the analyses. Because men compared to women have been reported to show higher scores on Dark Triad variables [44,45], we recruited male participants only to avoid floor effects among the predictor variables. Participants received £1.25 (approximately US$1.5) as compensation and could gain another £0.5 as a bonus for themselves or charity.
The study used a mixed design with two independent variables that were orthogonally manipulated between participants: Construal Level (abstract vs. concrete) and the recipient of a small monetary bonus (participants vs. a charitable organization), which could be won at the end of the experiment. Participants were randomly assigned to conditions. Furthermore, we assessed individuals’ traits (see Materials). As the dependent variable we assessed the likelihood of participants winning a bonus payment of £0.5 (see Materials and Procedure for the exact setup).
Materials and procedure
Participants first gave informed consent, before working on the different parts of the study listed below.
Assessment of individual differences of participants. Participants first completed several personality and value scales, such as the Twenty Item Values Inventory [46] with statements such as “S/he believes s/he should always show respect to his/her parents and to older people. It is important to him/her to be obedient” rated on a scale from 1 = very much like me to 6 = not like me at all. Cronbach’s alpha for these scales was: Conformity = .61, Tradition = .53, Benevolence = .77, Universalism = .77, Self Direction = .59, Stimulation = .70, Hedonism = .75, Achievement = .76, Power = .85, Security = .24. Next, they completed the Competitive Jungle Social World View Scale [35], rating statements such as “Winning is not the first thing; it’s the only thing” on a scale from 1 = very strongly disagree to 9 = very strongly agree (Cronbach’s alpha = .93). They then completed the Narcissistic Personality Inventory [47], choosing between two options each, for example “I have a natural talent for influencing people” versus “I am not good at influencing people” (Cronbach’s alpha = .90). Participants then worked on the MACH-IV scale to assess Machiavellianism [4], rating statements such as “Never tell anyone the real reason you did something unless it is useful to do so” on a scale from 1 = strongly disagree to 5 = strongly agree (Cronbach’s alpha = .84). Next, they completed the Multidimensional Belief in a Just World scale [34], rating statements such as “I think that I deserve the reputation I have among the people who know me” on a scale from 1 = strongly disagree to 7 = strongly agree (Cronbach’s Alpha = .70). Lastly, participants completed one scale to asses Extraversion [48], rating statements such as “I see myself as someone who is talkative” on a scale from 1 = disagree strongly to 5 = agree strongly (Cronbach’s alpha = .90).
Manipulation of construal level. Next, participants completed a construal level manipulation. Participants were randomly assigned to a concrete or abstract construal level condition and asked to either think about why (abstract level) or how (concrete level) they would try to reach an objective of improving and maintaining one’s physical health [49].
Assessment of cheating behavior. Subsequently, participants were introduced to a coin toss, with which we assessed cheating behavior on the group level (see S2 Fig for the instructions’ specific wording). As cheating is not a socially desirable behavior, we decided to use a more anonymous and subtle paradigm to detect this behavior. This paradigm was developed from the Randomized Response Technique [50] and has been extensively used in the past to study dishonesty, e.g., [51–53]. In this paradigm, participants are asked to toss a coin (or a die, see e.g. [54] once to determine whether or not they would win a bonus payment and in which they self-report the outcome. They do so at home, and we did not provide any link to an online coin flip animation, as we did not want to raise any suspicion that we might record the outcome. In our instructions participants were informed at the very beginning that the study would require a coin and that they should ensure that they had one beside them. At the end of the study they were then asked to flip the coin and self-report the outcome (see S2 Fig). Winning the bonus was coded as 1, and not winning the bonus was coded as 0. By this means, cheating cannot be detected on the individual level, as it is impossible for the researchers to know whether an individual actually tossed heads or tails. However, on the group level, a significant deviance from chance (.5) can be interpreted as indication of cheating and dishonesty in this group.
Within this setup we varied whether the bonus could be won for either the participants themselves or for a charitable organization, to contrast a self-serving condition (i.e., participants themselves benefit from deceptive behavior) to an other-serving condition (i.e., the charity organization UNICEF could benefit from deceptive behavior). Moreover, for methodological reasons, we counterbalanced whether the bonus was won for tossing heads or tossing tails. After self-reporting the result of the coin toss, participants were thanked and received the code for their compensation.
Results
Manipulation check construal level. To investigate the success of our construal level manipulation, we followed a procedure introduced by Fujita, Trope, Liberman, and Levin-Sagi [55] and asked two independent coders, who were blind to the construal level conditions, to rate the answers of participants’ reasoning on how/why to increase and maintain one’s physical health. If a response served as a means to the end of increasing health (indicating a low construal level), answers were coded as -1. If the response served as an end of the means of increasing health, answers were coded as +1. Answers without a clear relation were coded as 0. Ratings of each participant’s four responses were then summed and averaged across the two raters (ICC = .90). This resulted in an index of level of construal with a potential range of – 4 to + 4; higher scores indicate higher levels of construal. Our results attest to the manipulation’s success by indicating that participants primed to an abstract construal level compared to a concrete construal level displayed a more abstract mindset, M = 3.14, SD = 1.05; M = -3.47, SD = 0.59; respectively; t(125.12) = 49.31, p < .001.
Results on dishonesty. In total, 118 out of 164 participants reported winning the bonus payment (72%). A binomial test indicated that this was higher than expected by chance (.50), p < .001. Theoretically, with a fair coin, half of the participants should have won the bonus, while the other half should not have won the bonus, so that a significant deviance from chance level is an indication of cheating on the group level. We analyzed the cheating behavior following the guidelines of Moshagen and Hilbig [56] using the R package RRreg (for correlation and regression analyses of randomized response data, see [57]). Prevalence of cheating can be estimated by taking into account (a) the baseline probability of winning (.50) and (b) the proportion of participants claiming to win a bonus (for further details, see [56]).
Calculations revealed that within our sample, 44% of participants were estimated to have been dishonest. Within the abstract construal level condition this number increased to 53%, whereas in the concrete condition it was 35%. In the condition where participants received a bonus, this number increased to 47%, and decreased to 41% when the bonus recipient was a charitable organization. Nevertheless, the logistic regression analysis indicated that neither the effect of condition, nor recipient, nor the interaction was significant (all Likelihood Ratio Tests < 0.36, ps > .552).
Next, we included the different trait measures (mean-centered) in the analysis and calculated separate logistic regressions with construal level (dummy coded with 0 = abstract construal level and 1 = concrete construal level), bonus recipient (dummy coded with 0 = participants as bonus receiver and 1 = charity as bonus receiver) and the respective trait measures on the likelihood of winning the bonus.
We first analyzed the impact of the Dark Triad variables Machiavellianism and narcissism. In this model, Machiavellianism significantly predicted cheating behavior, b = 6.37, SE b = 4.53, Likelihood Ratio Test = 8.79, p = .003. This effect was qualified by an interaction between bonus recipient and Machiavellianism, b = -7.45, SE b = 4.69, Likelihood Ratio Test = 7.69, p = .006 and, in tendency, by the predicted three-way interaction between bonus recipient, construal level, and Machiavellianism, b = 8.01, SE b = 5.23, Likelihood Ratio Test = 3.81, p = .051. To disentangle the reported three-way interaction, we calculated correlations between Machiavellianism and the probability of winning the bonus for the four conditions of abstract construal level * participant as bonus recipient (r = .38, t(40) = 2.60, p = .013), concrete construal level * participant as bonus recipient (r = -.03, t(35) = -0.17, p = .864), abstract construal level * charity as bonus recipient (r = -.15, t(37) = -0.92, p = .363), concrete construal level * charity as bonus recipient (r = .02, t(44) = 0.16, p = .877). For participants as bonus recipients, higher scores on Machiavellianism are associated with an increased probability of “winning” the bonus–but only under abstract and not under concrete construal level. For charity as bonus recipients, the interaction pattern appears to be the opposite: When looking at the correlations descriptively, under abstract construal level higher scores on Machiavellianism are associated with a decreased probability of “winning” the bonus, while under concrete construal level the association appears to be weaker. However, although the three-way interaction indicates that the two-way interaction terms differ between the two between-subjects conditions, the two two-way interactions were not significant, ps > .066. Fig 1 summarizes the findings.
Fig. 1. Depiction of the three-way interaction between bonus recipient, construal level, and Machiavellianism scores (mean centered). Figures were created using a logistic regression model. Narcissism (the total score resulting from the Narcissistic Personality Inventory), in contrast, was not a significant predictor for dishonest behavior. No main or interaction effects reached significance, all Likelihood Ratio Tests < 0.86, all ps > .354 (see Table 1 for the exact inferential statistics for this and all following regression analyses). Going beyond the Dark Triad, we analyzed the impact of a jungle world view and, turning more towards the values of virtue, belief in a just world. Both concepts did not significantly predict dishonest behavior (results depicted in Table 1). The same applies for the 10 basic human values of Schwartz (results depicted in S1 Fig).
Tab. 1. Summary of Study 1 regression analyses predicting cheating behavior. As predicted, extraversion was not significantly related to dishonest behavior, all Likelihood Ratio Tests < 3.45, all ps > .062. Table 1 and S1 Fig summarize the results of all conducted analyses. Importantly, regression analyses for randomized response data revealed numeric instabilities when estimating the full model for Belief in A Just World and Extraversion. We therefore omitted one interaction term (construal level and bonus recipient) that is neither conceptually important nor proved to be empirically relevant in the present study.
Discussion
This first exploratory study suggests that higher scores of Machiavellianism lead to an increasing likelihood of winning a bonus and therefore supports Hypothesis 1. In line with our theorizing regarding Hypothesis 2, this relation might differ depending on participants’ construal level and the bonus recipient. Most importantly, when participants are able to win a bonus for themselves and construe the task abstractly, a significant positive correlation between Machiavellianism scores and winning probability occurs, attesting to increased cheating behavior. But this correlation drops to zero under concrete construal. The relations between Machiavellianism, construal level, bonus recipient, and dishonest behavior are especially interesting as they seem to be unique for this variable. Having said this, the exploratory nature of Study 1 needs to be acknowledged and addressed in Study 2.
Study 2
Study 1 provides first support that Machiavellianism predicts dishonest behavior and that when individuals construe abstractly, stronger Machiavellian tendencies increase the probability of winning a bonus in self-serving conditions. However, this first study was exploratory by nature. Study 2 was therefore conducted to replicate these findings in a confirmatory study, focusing on Machiavellianism and the self-serving bonus condition only.
Method
Participants and design
Sample size was determined based on the effect size (differences between slopes for linear bivariate regressions) of Study 1, a power of .90, and an alpha-level of .05, resulting in 242 participants [58]. Two hundred forty-two male US-American participants were recruited for a “Personality study” via prolific academic. Although the requirements of the study indicated that we were only recruiting male participants, two participants indicated their gender as female and one refrained from answering. Because it is unclear whether these data points represent true answers or reflect “misclicking,” we decided to retain these “female” data points in the sample. Excluding them did not change the pattern or significance levels in our Machiavellianism-regression analysis.
Individuals who had participated in Study 1 were not able to participate. Two hundred forty-two participants (Mage = 30.21 years, SD = 9.84) completed the study by self-reporting the coin toss’ outcome, which served as our main dependent variable. One person indicated that his data should not be used, and we therefore excluded this participant from further analyses. Participants received £0.66 (approximately US$0.66) as compensation and could gain another £0.5 as a bonus for themselves.
The study used a mixed design with Construal Level (abstract vs. concrete, dummy coded with 0 = abstract construal and 1 = concrete construal) as an independent between factor with random assignment. Individuals’ trait level of Machiavellianism served as a second independent variable. The likelihood of participants winning a bonus of £0.5 for themselves was the dependent variable.
Materials and procedure
Participants first gave informed consent, before working on the different parts of the study. The setup was similar to Study 1 with the following changes. First, all participants could win the bonus payment for themselves. Second, participants completed the MACH-IV scales only, as Study 2 was designed to confirm the stronger association between Machiavellianism under abstract compared to concrete construal level found in Study 1. Cronbach’s alpha for the MACH-IV scale was .75.
Results
Manipulation check construal level. To investigate the success of our construal level manipulation, we followed the procedure described in Study 1. The ICC across our two judges was .92. Our results indicate that participants primed to an abstract construal level compared to a concrete construal level displayed a more abstract mindset, M = 3.35, SD = 0.98; M = -3.35, SD = 0.86; respectively; t(239) = 56.28, p < .001, thus attesting to the manipulation’s success.
Results on dishonesty. In total, 159 out of 241 participants reported winning the bonus payment (66%). A binomial test indicates that this proportion of wins was higher than expected by chance (.50), p < .001. We analyzed the cheating behavior following the guidelines of Moshagen and Hilbig [56] using the R package RRreg [57]. Calculations revealed that within our sample, 32% of participants were estimated to have been dishonest. Within the abstract construal condition this number decreased to only 19%, while in the concrete construal condition it was 44%. The logistic regression analysis indicated that Machiavellianism (mean centered) significantly predicts dishonesty in this model (b = 4.03, SE b = 2.56, Likelihood Ratio Test = 5.14, p = .023). Furthermore, construal level was a significant predictor, (b = 1.63, SE b = 1.19, Likelihood Ratio Test = 4.58, p = .032), indicating that concrete construal participants were more likely to act dishonestly than participants in the abstract construal condition. Interestingly, the predicted two-way interaction between the two predictors is significant, b = -4.34, SE b = 2.66, Likelihood Ratio Test = 5.04, p = .025 (see Fig 2). Study 2 therefore replicates the pattern observed in Study 1.
Fig. 2. Depiction of the two-way interaction between construal level and Machiavellianism (mean centered). Figures were created by using a logistic regression model. To disentangle the two-way interaction, we calculated correlations between Machiavellianism and the probability of winning the bonus for the two construal level conditions. In the abstract condition, higher Machiavellianism scores were associated with a higher probability of winning, r = .17, t(117) = 1.88, p = .062, while Machiavellianism was not associated with a higher probability of winning in the concrete construal condition, r = -.04, t(120) = -0.46, p = .650. The significant two-way interaction indicates that these two slopes are different from each other.
Discussion
The results from Study 2 replicate the findings from Study 1 in a confirmatory, well-powered setting with a new sample. Stronger Machiavellianism scores were associated with a higher likelihood for dishonest behavior. Furthermore, this association was more pronounced under abstract construal level, while there was no such relation under concrete construal. As predicted by Construal Level Theory, the personality trait Machiavellianism impacted behavior more strongly when construing on a more abstract level.
Interestingly, in Study 2, cheating was more pronounced in conditions of concrete construal, while no statistically significant main effect was observed in Study 1. Our theorizing did not suggest ex ante predictions for main effects. This may possibly be a result of statistical power, that is, the ex ante likelihood of detecting effects if they are there, which was much higher in Study 2 than Study 1. While we had not specified ex ante predications for main effects, it is interesting to note that a main effect of construal level is in line with findings reported by other authors, e.g., [28]. To gauge this main effect’s reliability, we conducted Study 3.
Study 3
Study 3 was an exact replication of Study 2 with the objective to learn more about the effects’ generalizability. The design, materials, as well as the procedure were identical to Study 2. Therefore, respective descriptions only mention differences or highlights.
Method
Participants
Sample size was determined based on the effect size (slope between Machiavellianism and probability of winning a bonus in the abstract condition) of Study 2, a power of .80, and an alpha-level of .05, resulting in 212 participants for the abstract condition (and 424 for the entire sample) [58]. We added 10% as a buffer to this number for potential exclusions (see below) and collected data from 486 participants. Male US-American participants were recruited for a “Personality study” via prolific academic. Four hundred eighty-six participants (Mage = 33.69 years, SD = 11.35) completed the study by self-reporting the coin toss’ outcome, which served as our main dependent variable. Eight persons indicated that their data should not be used, and we therefore excluded these participants from further analyses. Furthermore, five participants stated their gender as female (despite only male individuals being admitted to the study), and were therefore excluded from further analyses, resulting in a sample of 473 participants. Participants received approximately US$ 1.01 (£0.77) as compensation and could gain another US$ 0.50 (£0.38) as a bonus for themselves.
Design, materials, and procedure
The design of Study 3, the materials and procedure were identical to Study 2. Cronbach’s alpha for the MACH-IV scale was .80 in Study 3.
Results
Manipulation check construal level. To investigate the success of our construal level manipulation, we followed the procedure described in Study 1. While looking at the coding of the answers, we observed that four participants had not completed the manipulation properly and two more had obviously participated twice. We excluded these six participants from further analyses. The ICC across two judges was .80. Results indicate that participants primed to an abstract construal level compared to a concrete construal level displayed a more abstract mindset, M = 2.68, SD = 1.86; M = -3.82, SD = 0.49; respectively; t(262.15) = 51.41, p < .001, thus attesting to the manipulation’s success.
Results on dishonesty. In total, 317 out of 467 participants reported winning the bonus payment (68%). A binomial test indicates that this proportion of wins was higher than expected by chance (.50), p < .001. Using the R package RRreg [57], 36% of participants were estimated to have been dishonest. Within the abstract construal condition this number increased to 40%, while in the concrete construal condition it was 32%. The logistic regression analysis indicated no significant main or interaction effects. Neither Machiavellianism (mean centered; b = 0.26, SE b = 0.52, Likelihood Ratio Test = 0.24, p = .623), nor construal level (b = -0.34, SE b = 0.38, Likelihood Ratio Test = 0.79, p = .373), or the interaction between the two predictor variables (b = -0.81, SE b = 0.80, Likelihood Ratio Test = 1.04, p = .309) significantly predicted the likelihood of winning a bonus.
Discussion
Study 3 does not replicate the pattern observed in Study 2. Neither the main effect for Machiavellianism, nor the main effect for construal level, nor the interaction between Machiavellianism and construal level were significant. Study 3 therefore does not confirm our hypotheses.
To understand what may account for these differences, we investigated potential differences between the samples in Studies 2 and 3. One aspect that caught our attention was participants’ mean age, which in Study 2 was lower than in Study 3 (MStudy2 = 30.21 versus MStudy3 = 33.69). Although this difference might seem negligible, it may prove important, because participant age and our key variable of interest, Machiavellianism, are negatively correlated, r(239) = -0.25, p < .001 in Study 2 and r(465) = -0.21, p < .001 in Study 3. This negative association has also been found in other work, e.g., [59]; Christie [60] further suggests that Machiavellianism scores might increase in adolescence (age 10 to age 16 or 17) and gradually decrease after the age of 40. We exploratorily analyzed only data from participants older than 22 and younger than 45 years old (+/ - 1 SD from the mean) and included age (centered) in the regression model. With this restricted (and likely underpowered) dataset, we find effects consistent with the hypotheses, namely for Machiavellianism (mean centered; b = 1.10, SE b = 0.89, Likelihood Ratio Test = 1.59, p = .207), construal level (b = -0.09, SE b = 0.51, Likelihood Ratio Test = 0.03, p = .860), and the interaction between the two predictor variables (b = -2.29, SE b = 1.24, Likelihood Ratio Test = 3.68, p = .055). These results indicate that a certain level of Machiavellianism scores may prove critical to uncover the predicted associations between Machiavellianism and cheating. However, because this analysis was conducted ex post, it needs to be treated with caution and a further replication appeared important.
Study 4
Study 3 did not replicate the results from Study 2. However, based on the exploratory results, one might speculate that a certain level of Machiavellianism scores is required to investigate the potential effects of Machiavellianism and construal level on dishonest behavior. Informed by the exploratory analysis of Study 3, we decided to conduct a further well-powered replication study that is identical to Studies 2 and 3, but limits participant age to the range of 18 to 40. We preregistered the entire study on aspredicted.org: http://aspredicted.org/blind.php?x=ub9y9w.
Method
Participants
Sample size was determined based on the effect size of Study 2, a power of .80, and an alpha-level of .05, resulting in a total of 424 participants [58]. To ensure that the sample size would meet the sample size in Study 3, we increased that number to 484 and added 10% as buffer to this number for potential exclusions (see below). In total we collected data from 532 participants. Male US-American participants were recruited for a “Personality study” via prolific academic and could only participate if they were between 18 and 40 years old and had not participated in the previous study. Although we had preregistered the age restriction before collecting the data, by a technical mistake, the filter was not applied at the beginning of the collection phase. Therefore, we had to collect data from another 128 participants. Data was not analyzed before completion of data collection; and all analyses reported here include only data from the preregistered sample of participants aged 18 to 40 years.
Five hundred thirty-three participants (Mage = 27.97 years, SD = 5.92) completed the study by self-reporting the coin toss’ outcome, which served as our main dependent variable. Nine persons indicated that their data should not be used, and therefore were excluded from further analyses. Furthermore, five participants stated their gender as female (despite only male individuals being admitted to the study) and three participants did not complete the manipulation successfully (see below), and were therefore excluded from analyses, resulting in a final sample of 516 participants. Participants received approximately US$ 0.90 (£0.69) as compensation and could gain another US$ 0.50 (£0.38) as a bonus for themselves.
Design, materials, and procedure
The design of Study 4, the materials and procedure were identical to Study 2. Cronbach’s alpha for the MACH-IV scale was .76.
Results
Manipulation check construal level. To investigate the success of our construal level manipulation, we followed the procedure described in Study 1. While looking at the coding of the answers, we found 3 participants had not completed the manipulation properly and were therefore excluded from further analyses. The ICC across two judges was .98. Results indicate that participants primed to an abstract construal level compared to a concrete construal level displayed a more abstract mindset, M = 3.82, SD = 0.87; M = -3.88, SD = 0.55; respectively; t(514) = 121.02, p < .001, thus attesting to the manipulation’s success.
Results on dishonesty. In total, 357 out of 516 participants reported winning the bonus payment (69%). A binomial test indicates that this proportion of wins was higher than expected by chance (.50), p < .001. Using the R package RRreg [57], 38% of participants were estimated to have been dishonest. Within the abstract construal condition this number dropped to 35%, while in the concrete construal condition it was 41%. The logistic regression analysis indicated no significant main or interaction effects. Neither Machiavellianism (mean centered; b = 0.71, SE b = 0.77, Likelihood Ratio Test = 0.90, p = .343), nor construal level (b = 0.23, SE b = 0.36, Likelihood Ratio Test = 0.41, p = .522), or the interaction between the two predictor variables (b = 0.03, SE b = 0.95, Likelihood Ratio Test = 0.00, p = .997) significantly predicted the likelihood of winning a bonus. Including age in the analysis did not change the resulting patterns.
Discussion
The results from Study 4 do not support our hypotheses that Machiavellianism (Hypothesis 1) and the interaction between Machiavellianism and construal level (Hypothesis 2) predict dishonest behavior. As in Study 3, the results in Study 4 do not replicate the findings from Study 2, although we used an identical design and collected data from a more age-homogeneous sample. Drawing conclusions appears difficult, as Studies 1 and 2 offer support, while Studies 3 and 4 do not. To gain insight into overall effects, we decided to pool the data from Studies 2, 3, and 4 into one overall data file and run a raw data analysis.
Integrative (meta) analysis across studies 2, 3, and 4
In order to test our hypotheses across the three identical studies in this manuscript, we pooled the data of Studies 2, 3, and 4 (total n = 1224) into one dataset and report the results below. In total, 833 out of 1224 participants reported winning the bonus payment (68%). A binomial test indicates that this proportion of wins was higher than expected by chance (.50), p < .001. Using the R package RRreg [57], 36% of participants were estimated to have been dishonest. Within the abstract construal condition this number dropped to 34%, while in the concrete construal condition it was 38% (see Table 2 for a summary of these estimates across all studies).
Tab. 2. Summary of estimates of proportions of dishonest participants across Studies and construal level conditions. The logistic regression analysis indicated no significant main or interaction effects. Neither Machiavellianism (mean centered; b = 0.73, SE b = 0.45, Likelihood Ratio Test = 2.80, p = .094), nor construal level (b = 0.20, SE b = 0.24, Likelihood Ratio Test = 0.70, p = .401), nor the interaction between the two predictor variables (b = -0.66, SE b = 0.57, Likelihood Ratio Test = 1.40, p = .236) significantly predicted the likelihood of winning a bonus. We summarize effect sizes, which have been calculated in line with the procedure reported in [61] in Table 3, which also provides an overview of the effect sizes for Studies 2, 3, and 4.
Tab. 3. Overview of effect size estimates (odds ratio) for model 1 (M1, original model) and model 2 (M2, including age). As we found a significant negative correlation between age and Machiavellianism in previous studies, we exploratorily investigated this association. Across the pooled data that includes the age-restricted sample of Study 4, Machiavellianism and age correlated negatively, r(1222) = -0.19, p < .001. We therefore again explored whether including age (mean centered) as main effect in the regression analysis would change the resulting pattern. Interestingly, it does. Neither Machiavellianism (mean centered; b = 0.68, SE b = 0.47, Likelihood Ratio Test = 2.12, p = .140), nor construal level (b = 0.23, SE b = 0.24, Likelihood Ratio Test = 0.92, p = .338), nor age (b = -0.02, SE b = 0.01, Likelihood Ratio Test = 2.06, p = .151) significantly predict the likelihood of winning a bonus. Furthermore, the interaction between Machiavellianism and construal level is not significant, (b = -0.71, SE b = 0.59, Likelihood Ratio Test = 1.50, p = .221). To exploratorily disentangle the interaction term, we looked at the correlations between Machiavellianism and winning probability separately for the high versus low construal conditions. Results indicate that in the high level condition, Machiavellianism and likelihood of winning correlate to r(593) = .06, p = .140 and in the low level condition to r(627) = .01, p = .843.
It should be noted that we did not pre-register the analysis with age as a covariate. These results, therefore, need to be treated with caution. Nevertheless, they allow for the speculation that the hypothesized relationship between Machiavellianism and cheating as a function of construal level additionally depends on participant age, most likely because Machiavellianism scores and participant age are negatively correlated.
General discussion
In this manuscript we investigated the impact of Machiavellianism on (dis)honest behavior using a coin toss paradigm. Results across four studies suggest that Machiavellianism did not significantly predict dishonest behavior. We also tested whether the relation between Machiavellianism and dishonest behavior was more pronounced in situations where individuals adopted a more abstract compared to concrete construal level, and when they personally benefited from the dishonest behavior. Results across studies were inconsistent and thus do not provide support for this interaction hypothesis. We summarize and discuss these findings in what follows.
Study 1 provided initial support for the hypothesized interaction between Machiavellianism and construal level on dishonest behavior, but was associated with two methodological caveats. First, because Study 1 initially tested the present hypothesis, we had no good estimate for the expected effect size and therefore relied on a rule of thumb as a sampling criterion. Ex post it appears that Study 1 was statistically underpowered, which may have resulted in the situation that associations were descriptively in line with our hypothesis, but did not reach significance. Furthermore, Study 1 was exploratory in nature, which together with the presumably low power, resulted in the requirement of a second, confirmatory Study 2. This Study 2 provided full support for the predicted main effect of Machiavellianism and dishonest behavior as well as for the interaction between Machiavellianism and construal level, showing that the association between Machiavellianism and dishonest behavior was stronger under abstract compared to concrete construal level. However, in Study 2 an unpredicted main effect for construal level on cheating was observed, and it appeared desirable to run well-powered follow-up studies to gauge reliability. Unfortunately, Studies 3 and 4 offer inconsistent evidence. Both studies did not provide support for the previously observed association between Machiavellianism and dishonest behavior. Furthermore, they did not support the interaction hypothesis between Machiavellianism and construal level on dishonest behavior. This picture is then strengthened by pooling the data from Studies 2, 3, and 4 and conducting a raw data meta analysis. Here again, we did not find support for Hypothesis 1 or Hypothesis 2.
In Study 3, exploratory analyses showed that participant age played an unexpectedly important role, as it was negatively correlated with Machiavellianism, see also [59,60]. Future research may fruitfully rely on these exploratory findings as a starting point.
Future research
Besides the interesting impact of age, future research could also check whether the negative association between Machiavellianism and participant age is associated to the MACH-IV scale used in this study, or generalizes to other scales, such as the Dirty Dozen [62], the Short Dark Triad (SD3) [63], or the Machiavellianism Personality Scale (MPS) [64]. It could also be commendable to develop and include measures reflecting the construct’s multifaceted conceptualization [65,66], to better understand differences and the differential impact of the facets of Machiavellianism. Here, we relied on the MACH-IV scale, which is assumed to be the “most important scale” [45], and persisted with this choice in Studies 3 and 4 to provide exact replications. If the negative association between Machiavellianism and participant age was specific to the MACH-IV scale, this choice could prove ill-informed in hindsight.
One limitation of our studies is that we did not include other potentially interesting variables, such as Honesty-Humility [25] or psychopathy [10]. Future research could therefore focus on these and other values and traits that have been linked to dishonest behavior and assess how they interact with individuals’ construal level. Moreover, future studies could introduce a temporal gap between the assessment of traits and the assessment of dishonest behavior. Such a gap would ensure against the potential caveat that assessing traits renders these unusually salient. If true, unusually high salience could artificially strengthen or reduce the traits’ impact on behavior.
In this contribution, we hypothesized that Machiavellianism is linked to behavior more strongly under abstract construal level, but did not find support for this hypothesis. This null-finding may dovetail with other evidence suggesting that the original finding of values on judgment as a function of psychological distance (related to abstract construal [67]) was replicated using some, but not all psychological distance manipulations [32]. Alper [68] describes differential effects as well, showing that in some cases abstract construal increased deception while in other cases it decreased deception. These findings suggest that our null-finding may be specific to the construal level manipulation we used, and may not necessarily generalize to other construal level manipulations. We opted for a manipulation that allowed manipulating construal level through goal priming, without affecting the related concept of psychological distance [69]. Furthermore, this manipulation has been well studied and used across a multitude of construal level studies, just to name a few, [28,70–76]. However, researchers have also noted that the manipulation has certain disadvantages, as it elicits different thought content in the different conditions [73]. Therefore, in retrospect, running exact replications in Studies 3 and 4 may not have been the best decision, as using different paradigms could have allowed for more far-reaching conclusions. Future studies could use alternatives such as the category versus exemplar task [55], or turn to manipulations that manipulate construal level by changing psychological distance, for example, by asking to think about the future versus today, a stranger versus yourself, a far-away place versus right here, or a very unlikely versus a very likely scenario, for an overview, see [29]. At the same time and concerning this manuscript, however, we believe that running exact replications allows for a rather firm conclusion that using the paradigms as we did does not uncover support for the suggested hypotheses.
It may also be interesting to replicate the current studies with different levels of bonus payments and compensations for the participants. In our studies, the bonus was quite high, with compensation resulting in a payment increase of, for example, 42% in Study 1 and 75% in Study 2. Arguably, such high bonuses might have invited higher levels of dishonesty in our overall sample. At the same time, it is interesting to note that reported winning probabilities in our study were only slightly lower than those in studies using similar designs, e.g., [53].
Last but not least, it may be fruitful to sample from populations that do not only include male participants, to investigate the effect across participant populations. Our choice was informed by prior research [44,45]; nevertheless, conclusions beyond the tested population can be more rigorous if other populations are tested, too.
Conclusion
In this manuscript we investigated the impact of Machiavellianism on (dis)honest behavior using a coin toss paradigm. We did not find support for the assumption that Machiavellianism significantly predicts dishonest behavior. Furthermore, we did not find support for an interaction between Machiavellianism and construal level on dishonest behavior. However, our research indicates that age might play a role when investigating the interaction between Machiavellianism and construal level and future research could fruitfully build on this exploratory finding to better understand predictors of dishonest behavior.
Supporting information
S1 Fig [docx]
Summary of Study 1 regression analyses on the 10 basic human values (Schwartz, 1992) predicting cheating behavior.S2 Fig [docx]
Screenshot of the instructions for the coin flip task.
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- High heat tolerance in plants from the Andean highlands: Implications for paramos in a warmer world
- Quantifying pediatric patient need for second- and third-line HIV treatment: A tool for decision-making in resource-limited settings
- Discovery of actionable genetic alterations with targeted panel sequencing in children with relapsed or refractory solid tumors
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- Fibre and extracellular matrix contributions to passive forces in human skeletal muscles: An experimental based constitutive law for numerical modelling of the passive element in the classical Hill-type three element model
- The status of imported Barremian-Bedoulian flint in north-eastern Iberia during the Middle Neolithic. Insights from the variscite mines of Gavà (Barcelona)
- Psychology of personal data donation
- Radiocarbon dating and cultural dynamics across Mongolia’s early pastoral transition
- MARGO (Massively Automated Real-time GUI for Object-tracking), a platform for high-throughput ethology
- Visual detection of time-varying signals: Opposing biases and their timescales
- Results from a World Health Organization pilot of the Basic Emergency Care Course in Sub Saharan Africa
- Scientists’ opinions and attitudes towards citizens’ understanding of science and their role in public engagement activities
- Dacentrurine stegosaurs (Dinosauria): A new specimen of Miragaia longicollum from the Late Jurassic of Portugal resolves taxonomical validity and shows the occurrence of the clade in North America
- Integrated pan-cancer gene expression and drug sensitivity analysis reveals SLFN11 mRNA as a solid tumor biomarker predictive of sensitivity to DNA-damaging chemotherapy
- Does membrane feeding compromise the quality of Aedes aegypti mosquitoes?
- Morphology, phylogeny, and taxonomy of two species of colonial volvocine green algae from Lake Victoria, Tanzania
- Metabolomics profiles associated with HbA1c levels in patients with type 2 diabetes
- Exploring local realities: Perceptions and experiences of healthcare workers on the management and control of drug-resistant tuberculosis in Addis Ababa, Ethiopia
- Sex differences in the treatment and outcome of emergency general surgery
- Comorbidities and costs in HIV patients: A retrospective claims database analysis in Germany
- Barriers to integration of bioinformatics into undergraduate life sciences education: A national study of US life sciences faculty uncover significant barriers to integrating bioinformatics into undergraduate instruction
- Local unemployment changes the springboard effect of low pay: Evidence from England
- A comparison of body composition assessment methods in climbers: Which is better?
- Comparison of an in-house ‘home-brew’ and commercial ViroSeq integrase genotyping assays on HIV-1 subtype C samples
- Elucidating genetic variability and population structure in Venturia inaequalis associated with apple scab diseaseusing SSR markers
- Clustering via hypergraph modularity
- Indomethacin enhances anti-tumor efficacy of a MUC1 peptide vaccine against breast cancer in MUC1 transgenic mice
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- Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A
- Pharmacological signatures of the reduced incidence and the progression of cognitive decline in ageing populations suggest the protective role of beneficial polypharmacy
- Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the “von Magnus effect”
- Complex interaction networks of cytokines after transarterial chemotherapy in patients with hepatocellular carcinoma
- Gender essentialism in transgender and cisgender children
- Insertional mutagenesis in the zoonotic pathogen Chlamydia caviae
- Being there: A scoping review of grief support training in medical education
- Does the psychological profile influence the position of promising young futsal players?
- Effect of self-rated health status on functioning difficulties among older adults in Ghana: Coarsened exact matching method of analysis of the World Health Organization’s study on global AGEing and adult health, Wave 2
- Olfactory screening of Parkinson’s Disease patients and healthy subjects in China and Germany: A study of cross-cultural adaptation of the Sniffin’ Sticks 12-identification test
- Molecular evolution of cytochrome C oxidase-I protein of insects living in Saudi Arabia
- Correlates of leisure-time sedentary behavior among 181,793 adolescents aged 12-15 years from 66 low- and middle-income countries
- Cost-effectiveness analysis of Mucosal Leishmaniasis diagnosis with PCR-based vs parasitological tests in Colombia
- Spatiotemporal analysis of historical records (2001–2012) on dengue fever in Vietnam and development of a statistical model for forecasting risk
- Resilience assessment of Puerto Rico’s coral reefs to inform reef management
- Effect of community based health education on knowledge and attitude towards iron and folic acid supplementation among pregnant women in Kiambu County, Kenya: A quasi experimental study
- Implementation and effectiveness of non-specialist mediated interventions for children with Autism Spectrum Disorder: A systematic review and meta-analysis
- A tailored cognitive behavioral program for juvenile justice-referred females at risk of substance use and delinquency: A pilot quasi-experimental trial
- Impact of adjusted kidney volume measured in the bench surgery on one-year renal function in kidney transplantation
- Machine learning algorithm validation with a limited sample size
- The magnitude of suicidal ideation, attempts and associated factors of HIV positive youth attending ART follow ups at St. Paul’s hospital Millennium Medical College and St. Peter’s specialized hospital, Addis Ababa, Ethiopia, 2018
- The nonlinear effect of financial and fiscal policies on poverty alleviation in China—An empirical analysis of Chinese 382 impoverished counties with PSTR models
- Impacts of risk and competition on the profitability of banks: Empirical evidence from Pakistan
- Molecular characterization of lung adenocarcinoma from Korean patients using next generation sequencing
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- Joint image compression and encryption based on sparse Bayesian learning and bit-level 3D Arnold cat maps
- Urticating setae of tarantulas (Araneae: Theraphosidae): Morphology, revision of typology and terminology and implications for taxonomy
- Live observation of the oviposition process in Daphnia magna
- On the accuracy of displacement-based wave intensity analysis: Effect of vessel wall viscoelasticity and nonlinearity
- Nodosilinea signiensis sp. nov. (Leptolyngbyaceae, Synechococcales), a new terrestrial cyanobacterium isolated from mats collected on Signy Island, South Orkney Islands, Antarctica
- A 3’ UTR SNP rs885863, a cis-eQTL for the circadian gene VIPR2 and lincRNA 689, is associated with opioid addiction
- Characterizing the Randot Preschool stereotest: Testability, norms, reliability, specificity and sensitivity in children aged 2-11 years
- Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells
- Amazon climatic factors driving terpene composition of Iryanthera polyneura Ducke in terra-firme forest: A statistical approach
- Differences in clinical features of cluster headache between drinkers and nondrinkers in Japan
- Distribution of macular ganglion cell layer thickness in foveal hypoplasia: A new diagnostic criterion for ocular albinism
- Polo-like kinase 1 (Plk1) inhibition synergizes with taxanes in triple negative breast cancer
- Effect of mechanochemical activation of natural phosphorite structure as well as phosphorus solubility
- Automated content analysis across six languages
- A deep learning reconstruction framework for X-ray computed tomography with incomplete data
- Integrating interconception care in preventive child health care services: The Healthy Pregnancy 4 All program
- The prognostic significance of tumor-infiltrating lymphocytes assessment with hematoxylin and eosin sections in resected primary lung adenocarcinoma
- Effectiveness of novel fabrics to resist punctures and lacerations from white shark (Carcharodon carcharias): Implications to reduce injuries from shark bites
- Bacillus Calmette-Guérin (BCG) therapy lowers the incidence of Alzheimer’s disease in bladder cancer patients
- Serial block-face scanning electron microscopy reveals neuronal-epithelial cell fusion in the mouse cornea
- Salt or fish (or salted fish)? The Bronze Age specialised sites along the Tyrrhenian coast of Central Italy: New insights from Caprolace settlement
- Pragmatic language dysfunction in systemic lupus erythematosus patients: Results from a single center Italian study
- Association between cerebral atrophy and osteoporotic vertebral compression fractures
- Latitudinal gradient of cyanobacterial diversity in tidal flats
- Gene expression based survival prediction for cancer patients—A topic modeling approach
- Understanding allergic multimorbidity within the non-eosinophilic interactome
- The association between psychological distress and angina pectoris: A population-based study
- Comparative analysis on Facebook post interaction using DNN, ELM and LSTM
- Cerebellum-mediated trainability of eye and head movements for dynamic gazing
- Psychological and physiological effects of applying self-control to the mobile phone
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- Genome-wide SNP analyses reveal population structure of Portunus pelagicus along Vietnam coastline
- Modulating transcription through development of semi-synthetic yeast core promoters
- Left-handed metamaterial bandpass filter for GPS, Earth Exploration-Satellite and WiMAX frequency sensing applications
- Cost-effectiveness analysis of PSA-based mass screening: Evidence from a randomised controlled trial combined with register data
- A good tennis player does not lose matches. The effects of valence congruency in processing stance-argument pairs
- Validation of the group tasks uncertainty model (MITAG) in a German sample
- Parent psychological wellbeing in a single-family room versus an open bay neonatal intensive care unit
- Optimizing the procedure of grain nutrient predictions in barley via hyperspectral imaging
- In-situ time resolved spectrographic measurement using an additively manufactured metallic micro-fluidic analysis platform
- Race disparity in blood sphingolipidomics associated with lupus cardiovascular comorbidity
- Characterization of the placental transcriptome through mid to late gestation in the mare
- Indirect violence exposure and mental health symptoms among an urban public-school population: Prevalence and correlates
- Diagnostic ability of multifocal electroretinogram in early multiple sclerosis using a new signal analysis method
- Predictors of never having a mammogram among Chinese, Vietnamese, and Korean immigrant women in the U.S.
- The impact of hepatic steatosis on portal hypertension
- How do and could clinical guidelines support patient-centred care for women: Content analysis of guidelines
- Study of the epidemiological behavior of malaria in the Darien Region, Panama. 2015–2017
- School-based obesity prevention for busy low-income families—Organisational and personal barriers and facilitators to implementation
- Neighborhood crime, disorder and substance use in the Caribbean context: Jamaica National Drug Use Prevalence Survey 2016
- Genomic comparison of diverse Salmonella serovars isolated from swine
- Significance of the lobe-specific emphysema index to predict prolonged air leak after anatomical segmentectomy
- Modeling of inter-organizational coordination dynamics in resilience planning of infrastructure systems: A multilayer network simulation framework
- Manipulating the odds: The effects of Machiavellianism and construal level on cheating behavior
- Early recognition of anorexia through patient-generated assessment predicts survival in patients with oesophagogastric cancer
- Identifying publications in questionable journals in the context of performance-based research funding
- ITGAM is a risk factor to systemic lupus erythematosus and possibly a protection factor to rheumatoid arthritis in patients from Mexico
- Nurses’ and patients’ experiences and preferences of the ankle-brachial pressure index and multi-site photoplethysmography for the diagnosis of peripheral arterial disease: A qualitative study
- Cluster tendency assessment in neuronal spike data
- Voluntary medical male circumcision for HIV prevention among adolescents in Kenya: Unintended consequences of pursuing service-delivery targets
- Primary care in five European countries: A citizens’ perspective on the quality of care for children
- High Order Profile Expansion to tackle the new user problem on recommender systems
- Psychometric properties of the Korean version of the Health Literacy on Social Determinants of Health Questionnaire (K-HL-SDHQ)
- Flood hazard mapping and assessment in data-scarce Nyaungdon area, Myanmar
- Methods for the identification of farm escapees in feral mink (Neovison vison) populations
- Transcriptional analysis of amino acid, metal ion, vitamin and carbohydrate uptake in butanol-producing Clostridium beijerinckii NRRL B-598
- Long-term vancomycin use had low risk of ototoxicity
- Overcoming platinum resistance in ovarian cancer by targeting pregnancy-associated plasma protein-A
- Exploration of muscle loss and metabolic state during prolonged critical illness: Implications for intervention?
- Pan-caspase inhibitor F573 mitigates liver ischemia reperfusion injury in a murine model
- Efficacy of interleukin 10 gene hydrofection in pig liver vascular isolated ‘in vivo’ by surgical procedure with interest in liver transplantation
- Molecular characteristics of segment 5, a unique fragment encoding two partially overlapping ORFs in the genome of rice black-streaked dwarf virus
- Early economic evaluation of MRI-guided laser interstitial thermal therapy (MRgLITT) and epilepsy surgery for mesial temporal lobe epilepsy
- GLADS: A gel-less approach for detection of STMS markers in wheat and rice
- Anterior tooth-use behaviors among early modern humans and Neandertals
- Incidence patterns of orofacial clefts in purebred dogs
- Capacity of the medullary cavity of tibia and femur for intra-bone marrow transplantation in mice
- Association of thoracic spine deformity and cardiovascular disease in a mouse model for Marfan syndrome
- Predicting atrial fibrillation in primary care using machine learning
- M3VR—A multi-stage, multi-resolution, and multi-volumes-of-interest volume registration method applied to 3D endovaginal ultrasound
- A developmental trajectory supporting the evaluation and achievement of competencies: Articulating the Mastery Rubric for the nurse practitioner (MR-NP) program curriculum
- Mobile medication manager application to improve adherence with immunosuppressive therapy in renal transplant recipients: A randomized controlled trial
- Default Mode Network structural alterations in Kocher-Monro trajectory white matter transection: A 3 and 7 tesla simulation modeling approach
- Phylogenetic revision of Gymnotidae (Teleostei: Gymnotiformes), with descriptions of six subgenera
- Population genetic analysis of 36 Y-chromosomal STRs yields comprehensive insights into the forensic features and phylogenetic relationship of Chinese Tai-Kadai-speaking Bouyei
- Prevention of suicidal behaviour: Results of a controlled community-based intervention study in four European countries
- An assessment of khat consumption habit and its linkage to household economies and work culture: The case of Harar city
- Fixation of genetic variation and optimization of gene expression: The speed of evolution in isolated lizard populations undergoing Reverse Island Syndrome
- One simple claudication question as first step in Peripheral Arterial Disease (PAD) screening: A meta-analysis of the association with reduced Ankle Brachial Index (ABI) in 27,945 subjects
- Direct cost of health care for individuals with community associated Clostridium difficile infections: A population-based cohort study
- Association between serum homocysteine level and cognitive function in middle-aged type 2 diabetes mellitus patients
- A qualitative research synthesis of contextual factors contributing to female overweight and obesity over the life course in sub-Saharan Africa
- Insight into the relationship between aryl-hydrocarbon receptor and β-catenin in human colon cancer cells
- Hidden noise in immunologic parameters might explain rapid progression in early-onset periodontitis
- The role of stigma in the acceptance and disclosure of HIV among recently diagnosed men who have sex with men in Australia: A qualitative study
- Detection of Schistosoma japonicum and Oncomelania hupensis quadrasi environmental DNA and its potential utility to schistosomiasis japonica surveillance in the Philippines
- Does age influence the quality of life in children with atopic dermatitis?
- Questioning the lasting effect of galvanic vestibular stimulation on postural control
- Identification of a novel monocytic phenotype in Classic Hodgkin Lymphoma tumor microenvironment
- Characterization of 20 complete plastomes from the tribe Laureae (Lauraceae) and distribution of small inversions
- Binding and dynamics of melatonin at the interface of phosphatidylcholine-cholesterol membranes
- Recent climate-driven ecological change across a continent as perceived through local ecological knowledge
- Nonalcoholic fatty liver disease is an early predictor of metabolic diseases in a metabolically healthy population
- Occurrence and multilocus genotyping of Giardia duodenalis from post-weaned dairy calves in Sichuan province, China
- Retinoic acid-stimulated ERK1/2 pathway regulates meiotic initiation in cultured fetal germ cells
- Gender disparities in scientific production: A nationwide assessment among physicians in Peru
- Effect of F1 and F2 generations on genetic variability and working steps of doubled haploid production in maize
- Mitochondrial dysfunction in rheumatoid arthritis: A comprehensive analysis by integrating gene expression, protein-protein interactions and gene ontology data
- A caspase-6-cleaved fragment of Glial Fibrillary Acidic Protein as a potential serological biomarker of CNS injury after cardiac arrest
- A handy method to remove bacterial contamination from fungal cultures
- The self-care profiles and its determinants among adults with hypertension in primary health care clinics in Selangor, Malaysia
- The mutational landscape of quinolone resistance in Escherichia coli
- Exploring the influence of self-perceptions on the relationship between motor competence and identity in adolescents
- Study on the damage characteristics of gas-bearing shale under different unloading stress paths
- EPILAT-IRA Study: A contribution to the understanding of the epidemiology of acute kidney injury in Latin America
- 16S rDNA droplet digital PCR for monitoring bacterial DNAemia in bloodstream infections
- Three-dimensional (3D) brain microphysiological system for organophosphates and neurochemical agent toxicity screening
- Diversity of endocervical microbiota associated with genital Chlamydia trachomatis infection and infertility among women visiting obstetrics and gynecology clinics in Malaysia
- Health impact of hepatic-venous-occlusive disease in a small town in Ethiopia—Case study from Tahtay koraro district in Tigray region, 2017
- Development of a novel automatable fabrication method based on electrospinning co electrospraying for rotator cuff augmentation patches
- Development of a quantitative PCR assay for the detection and enumeration of a potentially ciguatoxin-producing dinoflagellate, Gambierdiscus lapillus (Gonyaulacales, Dinophyceae)
- Association of clinical factors with survival outcomes in laryngeal squamous cell carcinoma (LSCC)
- Seasonal oyster harvesting recorded in a Late Archaic period shell ring
- Population preferences for breast cancer screening policies: Discrete choice experiment in Belarus
- Respiratory health and inflammatory markers - Exposure to respirable dust and quartz and chemical binders in Swedish iron foundries
- Trends and predictors of mother-to-child transmission of HIV in an era of protocol changes: Findings from two large health facilities in North East Nigeria
- Elevated Ki-67 (MIB-1) expression as an independent predictor for unfavorable pathologic outcomes and biochemical recurrence after radical prostatectomy in patients with localized prostate cancer: A propensity score matched study
- Genome-wide identification and gene expression analysis of SOS family genes in tuber mustard (Brassica juncea var. tumida)
- Carvedilol improves glucose tolerance and insulin sensitivity in treatment of adrenergic overdrive in high fat diet-induced obesity in mice
- Institutional differences in USMLE Step 1 and 2 CK performance: Cross-sectional study of 89 US allopathic medical schools
- Molecular epidemiological characteristics of dengue virus carried by 34 patients in Guangzhou in 2018
- Heteroplasmy in the complete chicken mitochondrial genome
- Candida blood stream infections observed between 2011 and 2016 in a large Italian University Hospital: A time-based retrospective analysis on epidemiology, biofilm production, antifungal agents consumption and drug-susceptibility
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- Association of uric acid in serum and urine with subclinical renal damage: Hanzhong Adolescent Hypertension Study
- Appropriate management of acute gastroenteritis in Australian children: A population-based study
- The plasma metabolome of women in early pregnancy differs from that of non-pregnant women
- Effectiveness of four types of neuraminidase inhibitors approved in Japan for the treatment of influenza
- More than just availability: Who has access and who administers take-home naloxone in Baltimore, MD
- Evaluating the cross-cultural validity of the Dutch version of the Social Exclusion Index for Health Surveys (SEI-HS): A mixed methods study
- Diminuendo al bottom—Clarifying the semantics of music notation by re-modeling
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- Serum uromodulin is associated with the severity of clinicopathological findings in ANCA-associated glomerulonephritis
- Male support for cervical cancer screening and treatment in rural Ghana
- ADAPTS: Automated deconvolution augmentation of profiles for tissue specific cells
- Comparison of shape quantification methods for genomic prediction, and genome-wide association study of sorghum seed morphology
- An attempt to identify the issues underlying the lack of consistent conceptualisations in the field of student mathematics-related beliefs
- Video abstracts and plain language summaries are more effective than graphical abstracts and published abstracts
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- Cost savings associated with timely treatment of botulism with botulism antitoxin heptavalent product
- Effects of light and nitrogen availability on photosynthetic efficiency and fatty acid content of three original benthic diatom strains
- Early signal detection of adverse events following influenza vaccination using proportional reporting ratio, Victoria, Australia
- Bioinformatic analysis of a novel Echinococcus granulosus nuclear receptor with two DNA binding domains
- Genome-wide identification and characterization, phylogenetic comparison and expression profiles of SPL transcription factor family in B. juncea (Cruciferae)
- Hypoxia inhibits TNF-α-induced TSLP expression in keratinocytes
- Conceptualising alcohol consumption in relation to long-term health conditions: Exploring risk in interviewee accounts of drinking and taking medications
- Elevated interleukin-25 and its association to Th2 cytokines in systemic lupus erythematosus with lupus nephritis
- Thrombocytopenia and thrombocytosis are associated with different outcome in atrial fibrillation patients on anticoagulant therapy
- Involvement of extracellular vesicles in the macrophage-tumor cell communication in head and neck squamous cell carcinoma
- Comparison of Humphrey Field Analyzer and imo visual field test results in patients with glaucoma and pseudo-fixation loss
- Out-of-pocket expenditure and catastrophic health expenditure for hospitalization due to injuries in public sector hospitals in North India
- Concurrent validity and discriminative ability of Dutch performance-based motor tests in 5 to 6 years old children
- Cumulative viral load as a predictor of CD4+ T-cell response to antiretroviral therapy using Bayesian statistical models
- Can General Practitioners manage mental disorders in primary care? A partially randomised, pragmatic, cluster trial
- Self-serving incentives impair collective decisions by increasing conformity
- Mutation and immune profiling of metaplastic breast cancer: Correlation with survival
- The clinicopathological significance of Thrombospondin-4 expression in the tumor microenvironment of gastric cancer
- Propofol-based total intravenous anesthesia did not improve survival compared to desflurane anesthesia in breast cancer surgery
- Association between ossification of the posterior longitudinal ligament and ossification of the nuchal ligament in the cervical spine
- Effects of Debaryomyces hansenii treatment on intestinal mucosa microecology in mice with antibiotic-associated diarrhea
- Molecular validation of clinical Pantoea isolates identified by MALDI-TOF
- A novel wheat lodging resistance evaluation method and device based on the thrust force of the stalks
- Evolution of high tooth replacement rates in theropod dinosaurs
- Outpatient facility-based order variation in combined imaging
- Ethnic-racial identity affirmation: Validation in Aboriginal Australian children
- Non-intubated anesthesia in patients undergoing video-assisted thoracoscopic surgery: A systematic review and meta-analysis
- Tissue-type plasminogen activator selectively inhibits multiple toll-like receptors in CSF-1-differentiated macrophages
- Changes of serum pentraxin-3 and hypersensitive CRP levels during pregnancy and their relationship with gestational diabetes mellitus
- Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake
- Investigating reindeer pastoralism and exploitation of high mountain zones in northern Mongolia through ice patch archaeology
- Diversity pattern of Plasmodium knowlesi merozoite surface protein 4 (MSP4) in natural population of Malaysia
- Protein synthesis rates of muscle, tendon, ligament, cartilage, and bone tissue in vivo in humans
- “What gets measured better gets done better”: The landscape of validation of global maternal and newborn health indicators through key informant interviews
- Contactless monitoring of heart and respiratory rate in anesthetized pigs using infrared thermography
- Molecular characterisation of genital human papillomavirus among women in Southwestern, Nigeria
- The impact of “male clinics” on health-seeking behaviors of adult men in rural Kenya
- Gene expression microarray public dataset reanalysis in chronic obstructive pulmonary disease
- Utility of the new cobas HCV test for viral load monitoring during direct-acting antiviral therapy
- Impact of negative tuberculin skin test on growth among disadvantaged Bangladeshi children
- Streptococcal phosphotransferase system imports unsaturated hyaluronan disaccharide derived from host extracellular matrices
- Maternal diet modulates placental nutrient transporter gene expression in a mouse model of diabetic pregnancy
- Effects of an incremental theory of personality intervention on the reciprocity between bullying and cyberbullying victimization and perpetration in adolescents
- The clot thickens: Autologous and allogeneic fibrin sealants are mechanically equivalent in an ex vivo model of cartilage repair
- Reproducibility, stability, and accuracy of microbial profiles by fecal sample collection method in three distinct populations
- Cooperation with autonomous machines through culture and emotion
- Variation in hybridogenetic hybrid emergence between populations of water frogs from the Pelophylax esculentus complex
- Breast cancer in Tanzanian, black American, and white American women: An assessment of prognostic and predictive features, including tumor infiltrating lymphocytes
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- A global overview of cassava genetic diversity
- Whole body periodic acceleration in normal and reduced mucociliary clearance of conscious sheep
- Identifying resurrection genes through the differentially expressed genes between Selaginella tamariscina (Beauv.) spring and Selaginella moellendorffii Hieron under drought stress
- Impact of hemodialysis on the concentrations of sodium and potassium during infusion of sodium thiosulfate using an In Vitro hemodialysis model
- Minimal effects of oyster aquaculture on local water quality: Examples from southern Chesapeake Bay
- Suboptimal infant and young child feeding practices in rural Boucle du Mouhoun, Burkina Faso: Findings from a cross-sectional population-based survey
- High salinity tolerance of invasive blue catfish suggests potential for further range expansion in the Chesapeake Bay region
- From waste to food: Optimising the breakdown of oil palm waste to provide substrate for insects farmed as animal feed
- Quantitative assessment of interstitial lung disease in Sjögren’s syndrome
- Comparative efficacy of tenofovir and entecavir in nucleos(t)ide analogue-naive chronic hepatitis B: A systematic review and meta-analysis
- Reference ranges for ultrasonographic renal dimensions as functions of age and body indices: A retrospective observational study in Taiwan
- Finding phrases: On the role of co-verbal facial information in learning word order in infancy
- Mathematical modeling reveals the factors involved in the phenomena of cancer stem cells stabilization
- Effects of forest management and roe deer impact on a mountain forest development in the Italian Apennines: A modelling approach using LANDIS-II
- Evaluation of comprehensive improvement for mild and moderate soil salinization in arid zone
- Efficacy, acceptability and feasibility of daily text-messaging in promoting glycaemic control and other clinical outcomes in a low-resource setting of South Africa: A randomised controlled trial
- Magnitude and associated factors of postpartum depression among women in Nekemte town, East Wollega zone, west Ethiopia, 2019: A community-based study
- Comparison of continuous wave and cold lateral condensation filling techniques in 3D printed simulated C-shape canals instrumented with Reciproc Blue or Hyflex EDM
- Effect of caffeine on neuromuscular function following eccentric-based exercise
- AtUBL5 regulates growth and development through pre-mRNA splicing in Arabidopsis thaliana
- The gut microbiome of freshwater Unionidae mussels is determined by host species and is selectively retained from filtered seston
- Alcohol consumption and survival after breast cancer diagnosis in Japanese women: A prospective patient cohort study
- Selection of reference genes for normalization of cranberry (Vaccinium macrocarpon Ait.) gene expression under different experimental conditions
- The household economic costs associated with depression symptoms: A cross-sectional household study conducted in the North West province of South Africa
- Increased cell size, structural complexity and migration of cancer cells acquiring fibroblast organelles by cell-projection pumping
- Acute low- compared to high-load resistance training to failure results in greater energy expenditure during exercise in healthy young men
- Impact of body mass index and metabolically unhealthy status on mortality in the Japanese general population: The JMS cohort study
- Characterization of two thermophilic cellulases from Talaromyces leycettanus JCM12802 and their synergistic action on cellulose hydrolysis
- Ecohydrology of urban trees under passive and active irrigation in a semiarid city
- Cyclosporine A eyedrops with self-nanoemulsifying drug delivery systems have improved physicochemical properties and efficacy against dry eye disease in a murine dry eye model
- LFastqC: A lossless non-reference-based FASTQ compressor
- Highly accurate prediction of flammability limits of chemical compounds using novel integrated hybrid models
- Nonsteroidal anti-inflammatory drugs and acetaminophen ameliorate muscular mechanical hyperalgesia developed after lengthening contractions via cyclooxygenase-2 independent mechanisms in rats
- A popular Indian clove-based mosquito repellent is less effective against Culex quinquefasciatus and Aedes aegypti than DEET
- Yeasts affect tolerance of Drosophila melanogaster to food substrate with high NaCl concentration
- The effect of climate change on cholera disease: The road ahead using artificial neural network
- Grit (effortful persistence) can be measured with a short scale, shows little variation across socio-demographic subgroups, and is associated with career success and career engagement
- Micro-dislodgement during transcatheter aortic valve implantation with a contemporary self-expandable prosthesis
- Improving the antimicrobial efficacy against resistant Staphylococcus aureus by a combined use of conjugated oligoelectrolytes
- Kin discrimination and outer membrane exchange in Myxococcus xanthus: Experimental analysis of a natural population
- Inflammatory cell infiltrates, hypoxia, vascularization, pentraxin 3 and osteoprotegerin in abdominal aortic aneurysms – A quantitative histological study
- Effects of virtual reality rehabilitation training on gait and balance in patients with Parkinson's disease: A systematic review
- Serum miR-33a is associated with steatosis and inflammation in patients with non-alcoholic fatty liver disease after liver transplantation
- Association between housing tenure and self-rated health in Japan: Findings from a nationwide cross-sectional survey
- Investigation of biochemical and physiological parameters of the newborn Saiga antelope (Saiga tatarica) in Gansu Province, China
- One-year follow-up of changes in refraction and aberrations induced by corneal incision
- Evaluation of upper limb superficial venous percussion as a sign of anatomical location and venous permeability. A comparative study of superficial venous percussion to ultrasound findings on non-renal patients and on chronic kidney disease patients
- An assessment of the Dutch experience with health insurers acting as healthcare advisors
- Perception of potential harm and benefits of HIV vaccine trial participation: A qualitative study from urban Tanzania
- Veterans with Gulf War Illness exhibit distinct respiratory patterns during maximal cardiopulmonary exercise
- Deep brain stimulation restores the glutamatergic and GABAergic synaptic transmission and plasticity to normal levels in kindled rats
- Metformin strongly affects transcriptome of peripheral blood cells in healthy individuals
- Cranberry extracts promote growth of Bacteroidaceae and decrease abundance of Enterobacteriaceae in a human gut simulator model
- Long-term retention on antiretroviral therapy among infants, children, adolescents and adults in Malawi: A cohort study
- Histochemical quantification of collagen content in articular cartilage
- Optogenetically transduced human ES cell-derived neural progenitors and their neuronal progenies: Phenotypic characterization and responses to optical stimulation
- Ion torrent high throughput mitochondrial genome sequencing (HTMGS)
- Outpatient antibiotic prescription rate and pattern in the private sector in India: Evidence from medical audit data
- Acute Influenza A virus outbreak in an enzootic infected sow herd: Impact on viral dynamics, genetic and antigenic variability and effect of maternally derived antibodies and vaccination
- Prevalence and correlates of low serum calcium in late pregnancy: A cross sectional study in the Nkongsamba Regional Hospital; Littoral Region of Cameroon
- Home-cage monitoring ascertains signatures of ictal and interictal behavior in mouse models of generalized seizures
- CRISPR/Cas9 gene editing in the West Nile Virus vector, Culex quinquefasciatus Say
- Genetic susceptibility to angiotensin-converting enzyme-inhibitor induced angioedema: A systematic review and evaluation of methodological approaches
- Proton pump inhibitor use increases the risk of peritonitis in peritoneal dialysis patients
- Comparative distribution of extended-spectrum beta-lactamase–producing Escherichia coli from urine infections and environmental waters
- Sex differences in thigh muscle volumes, sprint performance and mechanical properties in national-level sprinters
- Maternal serum and cord blood leptin concentrations at delivery
- Winter nitrification in ice-covered lakes
- Intolerance of uncertainty fuels depressive symptoms through rumination: Cross-sectional and longitudinal studies
- Monitoring exercise-induced muscle damage indicators and myoelectric activity during two weeks of knee extensor exercise training in young and old men
- Can adoption of pollution prevention techniques reduce pollution substitution?
- The association between self-efficacy and self-management behaviors among Chinese patients with type 2 diabetes
- Poly-arginine-18 peptides do not exacerbate bleeding, or improve functional outcomes following collagenase-induced intracerebral hemorrhage in the rat
- Affective disorders in the elderly in different European countries: Results from the MentDis_ICF65+ study
- Evaluation of forearm vascular resistance during orthostatic stress: Velocity is proportional to flow and size doesn’t matter
- Proton pencil minibeam irradiation of an in-vivo mouse ear model spares healthy tissue dependent on beam size
- Maternal stress in Shank3ex4-9 mice increases pup-directed care and alters brain white matter in male offspring
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- Exploiting open source 3D printer architecture for laboratory robotics to automate high-throughput time-lapse imaging for analytical microbiology
- Long non-coding RNAs and latent HIV – A search for novel targets for latency reversal
- Clinical characteristics of neonatal fulminant necrotizing enterocolitis in a tertiary Children's hospital in the last 10 years
- Effects of neuromuscular electrical stimulation training on muscle size in collegiate track and field athletes
- Adaptive fuzzy flow rate control considering multifractal traffic modeling and 5G communications
- Evaluation of four commercial tests for detecting ceftiofur in waste milk bulk tank samples
- A smart tele-cytology point-of-care platform for oral cancer screening
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- Microbial metabolisms in an abyssal ferromanganese crust from the Takuyo-Daigo Seamount as revealed by metagenomics
- Incidence of chronic kidney disease hospitalisations and mortality in Espírito Santo between 1996 to 2017
- The impact of short-term machine perfusion on the risk of cancer recurrence after rat liver transplantation with donors after circulatory death
- Proteomic profiling of the thrombin-activated canine platelet secretome (CAPS)
- Blood metal levels and serum testosterone concentrations in male and female children and adolescents: NHANES 2011–2012
- The effects of prolonged single night session of videogaming on sleep and declarative memory
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- Mapping developmental QTL for plant height in soybean [Glycine max (L.) Merr.] using a four-way recombinant inbred line population
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- Positive selection and precipitation effects on the mitochondrial NADH dehydrogenase subunit 6 gene in brown hares (Lepus europaeus) under a phylogeographic perspective
- Evaluation of Minimum Inhibitory Concentrations for 154 Mycoplasma synoviae isolates from Italy collected during 2012-2017
- Enhancement of antibiotics antimicrobial activity due to the silver nanoparticles impact on the cell membrane
- Correction: Smoking, alcohol use disorder and tuberculosis treatment outcomes: A dual co-morbidity burden that cannot be ignored
- Correction: Effect of corruption on perceived difficulties in healthcare access in sub-Saharan Africa
- Knowledge-based best of breed approach for automated detection of clinical events based on German free text digital hospital discharge letters
- Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects
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- Verification of hub genes in the expression profile of aortic dissection
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- Diagnostic value of ASVS for insulinoma localization: A systematic review and meta-analysis
- Newly educated care managers’ experiences of providing care for persons with stress-related mental disorders in the clinical primary care context
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- Qualification programmes for immigrant health professionals: A systematic review
- An analytical model to minimize the latency in healthcare internet-of-things in fog computing environment
- Grain filling of early-season rice cultivars grown under mechanical transplanting
- Intercalation of small molecules into DNA in chromatin is primarily controlled by superhelical constraint
- Correlative evidence for co-regulation of phosphorus and carbon exchanges with symbiotic fungus in the arbuscular mycorrhizal Medicago truncatula
- How to design a dose-finding study on combined agents: Choice of design and development of R functions
- Altered expression of Notch1 in Alzheimer's disease
- The ZJU index is a powerful surrogate marker for NAFLD in severely obese North American women
- Trunk velocity-dependent Light Touch reduces postural sway during standing
- Evaluation of cytological diagnostic accuracy for canine splenic neoplasms: An investigation in 78 cases using STARD guidelines
- Trade-offs in motivating volunteer effort: Experimental evidence on voluntary contributions to science
- Does caching strategy vary with microclimate in endangered Mt. Graham red squirrels?
- Assessment of energy expenditure during high intensity cycling and running using a heart rate and activity monitor in young active adults
- Evaluating rectal swab collection method for gut microbiome analysis in the common marmoset (Callithrix jacchus)
- Implementation of a screening, brief intervention and referral to treatment programme for risky substance use in South African emergency centres: A mixed methods evaluation study
- Can the CalproQuest predict a positive Calprotectin test? A prospective diagnostic study
- The calcium sensor OsCBL1 modulates nitrate signaling to regulate seedling growth in rice
- Acceptability of and treatment preferences for recurrent bacterial vaginosis—Topical lactic acid gel or oral metronidazole antibiotic: Qualitative findings from the VITA trial
- Mathematical determination of the HIV-1 matrix shell structure and its impact on the biology of HIV-1
- Contingent negative variation during a modified cueing task in simulated driving
- CAMDI interacts with the human memory-associated protein KIBRA and regulates AMPAR cell surface expression and cognition
- Effect of feeding patterns on growth and nutritional status of children aged 0-24 months: A Chinese cohort study
- A fecal sequel: Testing the limits of a genetic assay for bat species identification
- Measuring the impact of chronic conditions and associated multimorbidity on health-related quality of life in the general population in Hong Kong SAR, China: A cross-sectional study
- Short and long-term clinical effectiveness and cost-effectiveness of a late-phase community-based balance and gait exercise program following hip fracture. The EVA-Hip Randomised Controlled Trial
- Vaccine cold chain in general practices: A prospective study in 75 refrigerators (Keep Cool study)
- Brazilian norms for the Bank of Standardized Stimuli (BOSS)
- Distinct varieties of aesthetic chills in response to multimedia
- Interaction between apolipoprotein E genotype and hypertension on cognitive function in older women in the Nurses’ Health Study
- Correction: Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study
- New formulation of the Gompertz equation to describe the kinetics of untreated tumors
- Development of visual perception of others’ actions: Children’s judgment of lifted weight
- Retrospective comparative analysis of intraocular lens calculation formulas after hyperopic refractive surgery
- Human vitreous concentrations of citicoline following topical application of citicoline 2% ophthalmic solution
- Development and validation of exhaled breath condensate microRNAs to identify and endotype asthma in children
- Arthroscopic release for frozen shoulder: Does the timing of intervention and diabetes affect outcome?
- Risk factors affecting dairy cattle protective grouping behavior, commonly known as bunching, against Stomoxys calcitrans (L.) on California dairies
- Acceleration of chemical shift encoding-based water fat MRI for liver proton density fat fraction and T2* mapping using compressed sensing
- Characterisation and microbial community analysis of lipid utilising microorganisms for biogas formation
- Sexuality in male partners of women with fibromyalgia syndrome: A qualitative study
- Exploring optimization strategies for improving explicit water models: Rigid n-point model and polarizable model based on Drude oscillator
- Artificial insemination with fresh, liquid stored and frozen thawed semen in dromedary camels
- Moving into an urban drug scene among people who use drugs in Vancouver, Canada: Latent class growth analysis
- Numerical study on the start and unstart phenomena in a scramjet inlet-isolator model
- Effects of dietary supplementation with apple peel powder on the growth, blood and liver parameters, and transcriptome of genetically improved farmed tilapia (GIFT, Oreochromis niloticus)
- Urban growth simulation in different scenarios using the SLEUTH model: A case study of Hefei, East China
- Chronic bronchitis without airflow obstruction, asthma and rhinitis are differently associated with cardiovascular risk factors and diseases
- Factors associated with medication adherence among people with diabetes mellitus in poor urban areas of Cambodia: A cross-sectional study
- Mammary microbiome of lactating organic dairy cows varies by time, tissue site, and infection status
- Force field generalization and the internal representation of motor learning
- Polyphenism of visual and chemical secondary sexually-selected wing traits in the butterfly Bicyclus anynana: How different is the intermediate phenotype?
- Minimal genetic differentiation of the malaria vector Nyssorhynchus darlingi associated with forest cover level in Amazonian Brazil
- The impact of leisure activities on older adults’ cognitive function, physical function, and mental health
- scafSLICR: A MATLAB-based slicing algorithm to enable 3D-printing of tissue engineering scaffolds with heterogeneous porous microarchitecture
- Association of serum leptin and adiponectin concentrations with echocardiographic parameters and pathophysiological states in patients with cardiovascular disease receiving cardiovascular surgery
- Operation of cognitive memory inhibition in adults with Down syndrome: Effects of maintenance load and material
- Influences on surgical antimicrobial prophylaxis decision making by surgical craft groups, anaesthetists, pharmacists and nurses in public and private hospitals
- Post-treatment Lyme disease symptoms score: Developing a new tool for research
- Expression of Concern: The Role of the RACK1 Ortholog Cpc2p in Modulating Pheromone-Induced Cell Cycle Arrest in Fission Yeast
- Equine bronchial fibroblasts enhance proliferation and differentiation of primary equine bronchial epithelial cells co-cultured under air-liquid interface
- Investigating cooperation with robotic peers
- Synthesis, purification and crystallization of a putative critical bulge of HAR1 RNA
- Prosthetic push-off power in trans-tibial amputee level ground walking: A systematic review
- A case study of the use of verbal reports for talent identification purposes in soccer: A Messi affair!
- Transgenerational deep sequencing revealed hypermethylation of hippocampal mGluR1 gene with altered mRNA expression of mGluR5 and mGluR3 associated with behavioral changes in Sprague Dawley rats with history of prolonged febrile seizure
- Obesity is associated with an impaired survival in lymphoma patients undergoing autologous stem cell transplantation
- Periodontal disease: Repercussions in pregnant woman and newborn health—A cohort study
- Origins of Chinese reindeer (Rangifer tarandus) based on mitochondrial DNA analyses
- Regional, racial, gender, and tumor biology disparities in breast cancer survival rates in Africa: A systematic review and meta-analysis
- How effective are films in inducing positive and negative emotional states? A meta-analysis
- 3D nanostructural characterisation of grain boundaries in atom probe data utilising machine learning methods
- An outbreak of tuberculosis in a middle school in Henan, China: Epidemiology and risk factors
- Initial clinical radiological findings and staging to predict prognosis of primary hepatic angiosarcoma: A retrospective analysis
- A new early Eocene deperetellid tapiroid illuminates the origin of Deperetellidae and the pattern of premolar molarization in Perissodactyla
- Longevity and marginal bone loss of narrow-diameter implants supporting single crowns: A systematic review
- Impact of UVC-sustained recirculating air filtration on airborne bacteria and dust in a pig facility
- Cold-related Florida manatee mortality in relation to air and water temperatures
- Conceptual fluency in inductive reasoning
- Clinical outcomes and treatment patterns among Medicare patients with nonvalvular atrial fibrillation (NVAF) and chronic kidney disease
- Improvements in the learnability of smartphone haptic interfaces for visually impaired users
- Role of the malic enzyme in metabolism of the halotolerant methanotroph Methylotuvimicrobium alcaliphilum 20Z
- Cyclic loading test study on a new cast-in-situ insulated sandwich concrete wall
- Natural compounds as angiogenic enzyme thymidine phosphorylase inhibitors: In vitro biochemical inhibition, mechanistic, and in silico modeling studies
- Analysis of virulence potential of Escherichia coli O145 isolated from cattle feces and hide samples based on whole genome sequencing
- Pre-clinical medical student reflections on implicit bias: Implications for learning and teaching
- Prognostic significance of non-sustained ventricular tachycardia on stored electrograms in pacemaker recipients
- Determinants of preterm birth among mothers who gave birth at public hospitals in the Amhara region, Ethiopia: A case-control study
- Real-world evidence of the effectiveness of ombitasvir-paritaprevir/r ± dasabuvir ± ribavirin in patients monoinfected with chronic hepatitis C or coinfected with human immunodeficiency virus-1 in Spain
- Unique transcriptomic landscapes identified in idiopathic spontaneous and infection related preterm births compared to normal term births
- Restrained expansion of the recall germinal center response as biomarker of protection for influenza vaccination in mice
- Arabidopsis TRM5 encodes a nuclear-localised bifunctional tRNA guanine and inosine-N1-methyltransferase that is important for growth
- Achievement of weight loss in patients with overweight during dietetic treatment in primary health care
- Autophagy deficiency exacerbates colitis through excessive oxidative stress and MAPK signaling pathway activation
- The impacts of parity on lung function data (LFD) of healthy females aged 40 years and more issued from an upper middle income country (Algeria): A comparative study
- Reorganization of spatial configurations in visual working memory: A matter of set size?
- Unravelling travellers’ route choice behaviour at full-scale urban network by focusing on representative OD pairs in computer experiments
- Evaluating the higher-order structure of the Profile of Emotional Competence (PEC): Confirmatory factor analysis and Bayesian structural equation modeling
- HIV prevalence and correlated factors among male clients of female sex workers in a border region of China
- Next generation sequencing and RNA-seq characterization of adipose tissue in the Nile crocodile (Crocodylus niloticus) in South Africa: Possible mechanism(s) of pathogenesis and pathophysiology of pansteatitis
- Association between advanced maternal age and maternal and neonatal morbidity: A cross-sectional study on a Spanish population
- Ethnic differences in the prevalence, socioeconomic and health related risk factors of knee pain and osteoarthritis symptoms in older Malaysians
- Increasing knowledge of HIV status in a country with high HIV testing coverage: Results from the Botswana Combination Prevention Project
- Friends with benefits: The effects of vegetative shading on plant survival in a green roof environment
- Comparison of the fecal, cecal, and mucus microbiome in male and female mice after TNBS-induced colitis
- Identifying candidate diagnostic markers for early stage of non-small cell lung cancer
- Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform
- Correction: KML001 Induces Apoptosis and Autophagic Cell Death in Prostate Cancer Cells via Oxidative Stress Pathway
- Unique developmental trajectories of risk behaviors in adolescence and associated outcomes in young adulthood
- Enhanced fibrinolysis detection in a natural occurring canine model with intracavitary effusions: Comparison and degree of agreement between thromboelastometry and FDPs, D-dimer and fibrinogen concentrations
- Overexpression of Saussurea involucrata dehydrin gene SiDHN promotes cold and drought tolerance in transgenic tomato plants
- Foxtail millet (Setaria italica (L.) P. Beauv) CIPKs are responsive to ABA and abiotic stresses
- Autonomous drone hunter operating by deep learning and all-onboard computations in GPS-denied environments
- Heterogeneity Diffusion Imaging of gliomas: Initial experience and validation
- Frequency cluster formation and slow oscillations in neural populations with plasticity
- DHP23002 as a next generation oral paclitaxel formulation for pancreatic cancer therapy
- Diagnostic accuracy of SOX11 immunohistochemistry in mantle cell lymphoma: A meta-analysis
- Analytical solution to swing equations in power grids
- Pathways to conspiracy: The social and linguistic precursors of involvement in Reddit’s conspiracy theory forum
- Spatiotemporally random and diverse grid cell spike patterns contribute to the transformation of grid cell to place cell in a neural network model
- Empathic concern and personal distress depend on situational but not dispositional factors
- Who is more susceptible to job stressors and resources? Sensory-processing sensitivity as a personal resource and vulnerability factor
- Cost-effectiveness of integrating postpartum antiretroviral therapy and infant care into maternal & child health services in South Africa
- A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling
- One step at a time: Physical activity is linked to positive interpretations of ambiguity
- Calreticulin regulates vascular endothelial growth factor-A mRNA stability in gastric cancer cells
- Evaluation of various methods of selection of B. subtilis strains capable of secreting surface-active compounds
- Association between US Pharmacopeia (USP) monograph standards, generic entry and prescription drug costs
- Molecular characterisation of the synovial fluid microbiome in rheumatoid arthritis patients and healthy control subjects
- On sorption hysteresis in wood: Separating hysteresis in cell wall water and capillary water in the full moisture range
- Inbreeding, Allee effects and stochasticity might be sufficient to account for Neanderthal extinction
- Reliability and construct validity of the stepping-forward affordance perception test for fall risk assessment in community-dwelling older adults
- Socioeconomic determinants of nutritional status among ‘Baiga’ tribal children In Balaghat district of Madhya Pradesh: A qualitative study
- Study on characteristics of fire plume in building facade window under lateral blow
- ‘When you talk to someone in a bad way or always put her under pressure, it is actually worse than beating her’: Conceptions and experiences of emotional intimate partner violence in Rwanda and South Africa
- Effects of 6-mercaptopurine in pressure overload induced right heart failure
- The association between haemoglobin levels in the first 20 weeks of pregnancy and pregnancy outcomes
- Implementation and evaluation of an antimicrobial stewardship programme in companion animal clinics: A stepped-wedge design intervention study
- Factors associated with persistently high-cost health care utilization for musculoskeletal pain
- Nitrogen and chlorophyll status determination in durum wheat as influenced by fertilization and soil management: Preliminary results
- Effect of repeated in vivo microCT imaging on the properties of the mouse tibia
- Coupling environment and physiology to predict effects of climate change on the taxonomic and functional diversity of fish assemblages in the Murray-Darling Basin, Australia
- Hematology and plasma biochemistries in the Blanding’s turtle (Emydoidea blandingii) in Lake County, Illinois
- CRISPR-Cas influences the acquisition of antibiotic resistance in Klebsiella pneumoniae
- Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors
- Antidepressant prescriptions, discontinuation, depression and perinatal outcomes, including breastfeeding: A population cohort analysis
- Why men with a low-risk prostate cancer select and stay on active surveillance: A qualitative study
- Imported severe malaria and risk factors for intensive care: A single-centre retrospective analysis
- Combined treatment (image-guided thrombectomy and endovascular therapy with open femoral access) for acute lower limb ischemia: Clinical efficacy and outcomes
- Low-latency single channel real-time neural spike sorting system based on template matching
- Quantifying the scale effect in geospatial big data using semi-variograms
- Paper-and-pencil versus computerized administration mode: Comparison of data quality and risk behavior prevalence estimates in the European school Survey Project on Alcohol and other Drugs (ESPAD)
- Regression adjusted colocalisation colour mapping (RACC): A novel biological visual analysis method for qualitative colocalisation analysis of 3D fluorescence micrographs
- Ostrich eggshell bead diameter in the Holocene: Regional variation with the spread of herding in eastern and southern Africa
- Spatial and temporal variations in female size at maturity of a Southern Rock Lobster (Jasus edwardsii) population: A likely response to climate change
- Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells
- Training rhesus macaques to take daily oral antiretroviral therapy for preclinical evaluation of HIV prevention and treatment strategies
- Left ventricular structural and functional changes in Friedreich ataxia – Relationship with body size, sex, age and genetic severity
- Magnitude and factors associated with anemia among pregnant women attending antenatal care in Bench Maji, Keffa and Sheka zones of public hospitals, Southwest, Ethiopia, 2018: A cross -sectional study
- Effectiveness of telerehabilitation in the management of adults with stroke: A systematic review
- Hydrogen sulphide-induced hypometabolism in human-sized porcine kidneys
- Correction: Comparison of the molecular properties of retinitis pigmentosa P23H and N15S amino acid replacements in rhodopsin
- Retraction: Regulation of gastric smooth muscle contraction via Ca2+-dependent and Ca2+-independent actin polymerization
- Evaluation of neutral oral contrast agents for assessment of the small bowel at abdominal staging CT
- Blood type and breed-associated differences in cell marker expression on equine bone marrow-derived mesenchymal stem cells including major histocompatibility complex class II antigen expression
- Induced abortion and future use of IVF treatment; A nationwide register study
- Psychosocial determinants of sustained maternal functional impairment: Longitudinal findings from a pregnancy-birth cohort study in rural Pakistan
- Measurement of finger joint angle using stretchable carbon nanotube strain sensor
- Determinants of mortality among patients with drug-resistant tuberculosis in northern Nigeria
- Drugs modulating stochastic gene expression affect the erythroid differentiation process
- Efficacy of UB0316, a multi-strain probiotic formulation in patients with type 2 diabetes mellitus: A double blind, randomized, placebo controlled study
- Prognostic value of des-γ-carboxy prothrombin in patients with hepatocellular carcinoma treated with transarterial chemotherapy: A systematic review and meta-analysis
- Avermectin induces the oxidative stress, genotoxicity, and immunological responses in the Chinese Mitten Crab, Eriocheir sinensis
- Antibiotic use in mandarin production (Citrus reticulata Blanco) in major mandarin-producing areas in Thailand: A survey assessment
- Application of CPI cutoff value based on parentage testing of duos and trios typed by four autosomal kits
- Correction: Good and Bad in the Hands of Politicians: Spontaneous Gestures during Positive and Negative Speech
- Adolescents with worse levels of oral health literacy have more cavitated carious lesions
- Effective methods for the inactivation of Francisella tularensis
- Detection of early-stage Alzheimer’s pathology using blood-based autoantibody biomarkers in elderly hip fracture repair patients
- Correlation between internal pudendal artery stenosis and erectile dysfunction in patients with suspected coronary artery disease
- Analysis of HER2 genomic binding in breast cancer cells identifies a global role in direct gene regulation
- Population productivity of shovelnose rays: Inferring the potential for recovery
- Correction: Long-term clinical outcomes in a cohort of patients with solitary plasmacytoma treated in the modern era
- Effects of tetracycline on myocardial infarct size in obese rats with chemically-induced colitis
- Mineral absorption is an enriched pathway in a brain region of restless legs syndrome patients with reduced MEIS1 expression
- Changes in weight and body composition across five years at university: A prospective observational study
- Adeno-associated virus-mediated expression of human butyrylcholinesterase to treat organophosphate poisoning
- Effects of insulin signaling on mouse taste cell proliferation
- Patient-level cost of home- and facility-based child pneumonia treatment in Suba Sub County, Kenya
- TAP: A static analysis model for PHP vulnerabilities based on token and deep learning technology
- Cost-effectiveness of QuantiFERON-TB Gold In-Tube versus tuberculin skin test for diagnosis and treatment of Latent Tuberculosis Infection in primary health care workers in Brazil
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- Changes over time in creatinine clearance and comparison of emergent adverse events for HIV-positive adults receiving standard doses (300 mg/day) of lamivudine-containing antiretroviral therapy with baseline creatinine clearance of 30–49 vs ≥50 mL/min
- Population dynamics of foxes during restricted-area culling in Britain: Advancing understanding through state-space modelling of culling records
- Impacts of experimental advisory exit speed sign on traffic speeds for freeway exit ramp
- In-hospital outcomes and 30-day readmission rates among ischemic and hemorrhagic stroke patients with delirium
- Monitoring quality indicators for the Xpert MTB/RIF molecular assay in Ethiopia
- Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids
- Correction: Using remote sensing to detect whale strandings in remote areas: The case of sei whales mass mortality in Chilean Patagonia
- Comparison of the inoculum size effects of antibiotics on IMP-6 β-lactamase-producing Enterobacteriaceae co-harboring plasmid-mediated quinolone resistance genes
- Contrast-enhanced computed tomography findings of canine primary renal tumors including renal cell carcinoma, lymphoma, and hemangiosarcoma
- Non-invasive in vivo imaging of UCP1 expression in live mice via near-infrared fluorescent protein iRFP720
- Overexpression of pink1 or parkin in indirect flight muscles promotes mitochondrial proteostasis and extends lifespan in Drosophila melanogaster
- Fiber stiffness, pore size and adhesion control migratory phenotype of MDA-MB-231 cells in collagen gels
- Comparison of two experimental ARDS models in pigs using electrical impedance tomography
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- Stroke risks in women with dysmenorrhea by age and stroke subtype
- Changes in patterns of mortality rates and years of life lost due to firearms in the United States, 1999 to 2016: A joinpoint analysis
- In vitro modeling of Batrachochytrium dendrobatidis infection of the amphibian skin
- Development and validation of LC-MS/MS method for imatinib and norimatinib monitoring by finger-prick DBS in gastrointestinal stromal tumor patients
- Correction: Habitat disturbance and the organization of bacterial communities in Neotropical hematophagous arthropods
- Characterisation of early metazoan secretion through associated signal peptidase complex subunits, prohormone convertases and carboxypeptidases of the marine sponge (Amphimedon queenslandica)
- Time trends between 2002 and 2017 in correlates of self-reported sitting time in European adults
- Performance of patient acuity rating by rapid response team nurses for predicting short-term prognosis
- Changes in HbA1c during the first six years after the diagnosis of Type 2 diabetes mellitus predict long-term microvascular outcomes
- Correction: Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry
- Correction: Mental health and quality of life outcomes in family members of patients with chronic critical illness admitted to the intensive care units of two Brazilian hospitals serving the extremes of the socioeconomic spectrum
- Correction: Establishing an infrastructure for collaboration in primate cognition research
- Correction: The impact of public health insurance on health care utilisation, financial protection and health status in low- and middle-income countries: A systematic review
- Health provider and service-user experiences of sensory modulation rooms in an acute inpatient psychiatry setting
- Comparison of potential drug-drug interactions with metabolic syndrome medications detected by two databases
- The Polish version of the Cultural Intelligence Scale: Assessment of its reliability and validity among healthcare professionals and medical faculty students
- Selection of optimal reference genes for qRT-PCR analysis of shoot development and graviresponse in prostrate and erect chrysanthemums
- Metastasis risk prediction model in osteosarcoma using metabolic imaging phenotypes: A multivariable radiomics model
- Defining hospital community benefit activities using Delphi technique: A comparison between China and the United States
- Establishment of the experimental procedure for prediction of conjugation capacity in mutant UGT1A1
- A robust multi-objective optimization framework to capture both cellular and intercellular properties in cardiac cellular model tuning: Analyzing different regions of membrane resistance profile in parameter fitting
- Sea star wasting disease demography and etiology in the brooding sea star Leptasterias spp.
- Diagnostic plasma miRNA-profiles for ovarian cancer in patients with pelvic mass
- Genetic diversity and drug resistance of HIV-1 among infected pregnant women newly diagnosed in Luanda, Angola
- I’ve been robbed! – Can changes in floral traits discourage bee pollination?
- Visualising statistical models using dynamic nomograms
- Assessing the capacity of Malawi’s district and central hospitals to manage traumatic diaphyseal femoral fractures in adults
- Diagnostic performance of basal cortisol level at 0900-1300h in adrenal insufficiency
- The Mastery Rubric for Bioinformatics: A tool to support design and evaluation of career-spanning education and training
- Microdissection and whole chromosome painting confirm karyotype transformation in cryptic species of the Lariophagus distinguendus (Förster, 1841) complex (Hymenoptera: Pteromalidae)
- Quality of Kangaroo Mother Care services in Ethiopia: Implications for policy and practice
- Gemcitabine potentiates the anti-tumour effect of radiation on medullary thyroid cancer
- iTRAQ-based high-throughput proteomics analysis reveals alterations of plasma proteins in patients infected with human bocavirus
- The detection of a non-anemophilous plant species using airborne eDNA
- Perception and control of low cable operation forces in voluntary closing body-powered upper-limb prostheses
- Neoadjuvant chemotherapy plus surgery versus concurrent chemoradiotherapy in stage IB2-IIB cervical cancer: A systematic review and meta-analysis
- Randomized methods to characterize large-scale vortical flow networks
- Disentangling the coexistence strategies of mud-daubing wasp species through trophic analysis in oases of Baja California peninsula
- Front-of-pack nutritional labels: Understanding by low- and middle-income Mexican consumers
- Distress in patients with end-stage renal disease: Staff perceptions of barriers to the identification of mild-moderate distress and the provision of emotional support
- Pathways to antibiotics in Bangladesh: A qualitative study investigating how and when households access medicine including antibiotics for humans or animals when they are ill
- DOC export is exceeded by C fixation in May Creek: A late-successional watershed of the Copper River Basin, Alaska
- Behavioral observation of prosocial behavior and social initiative is related to preschoolers’ psychopathological symptoms
- Evaluating the impact of citations of articles based on knowledge flow patterns hidden in the citations
- Correction: Economic sanctions and academia: Overlooked impact and long-term consequences
- Correction: A novel association between relaxin receptor polymorphism and hematopoietic stem cell yield after mobilization
- Expression of Concern: Cooperativity of Oncogenic K-Ras and Downregulated p16/INK4A in Human Pancreatic Tumorigenesis
- Price dispersion of generic medications
- Sex differences in body composition but not neuromuscular function following long-term, doxycycline-induced reduction in circulating levels of myostatin in mice
- The emotion regulation effect of cognitive control is related to depressive state through the mediation of rumination: An ERP study
- Comparison of SMS-EPI and 3D-EPI at 7T in an fMRI localizer study with matched spatiotemporal resolution and homogenized excitation profiles
- Left ventricular mass normalization for body size in children based on an allometrically adjusted ratio is as accurate as normalization based on the centile curves method
- Correction: Combining biophysical parameters, spectral indices and multivariate hyperspectral models for estimating yield and water productivity of spring wheat across different agronomic practices
- Correction: Flowers as viral hot spots: Honey bees (Apis mellifera) unevenly deposit viruses across plant species
- 'Small small quarrels bring about happiness or love in the relationships’: Exploring community perceptions and gendered norms contributing to male perpetrated intimate partner violence in the Central Region of Ghana
- The performance of practitioners conducting facial comparisons on images of children across age
- Increased amounts and stability of telomeric repeat-containing RNA (TERRA) following DNA damage induced by etoposide
- Patients with limitation or withdrawal of life supporting care admitted in a medico-surgical intermediate care unit: Prevalence, description and outcome over a six-month period
- Correction: Diverse radiofrequency sensitivity and radiofrequency effects of mobile or cordless phone near fields exposure in Drosophila melanogaster
- Predicting the performance of TV series through textual and network analysis: The case of Big Bang Theory
- Risk of temperature, humidity and concentrations of air pollutants on the hospitalization of AECOPD
- Mixed methods grant applications in the health sciences: An analysis of reviewer comments
- Renal abnormalities among children with sickle cell conditions in highly resource-limited setting in Ghana
- Size matters: How reaching and vergence movements are influenced by the familiar size of stereoscopically presented objects
- Willingness to receive institutional and community-based eldercare among the rural elderly in China
- An improved deep learning method for predicting DNA-binding proteins based on contextual features in amino acid sequences
- Beyond executive functions, creativity skills benefit academic outcomes: Insights from Montessori education
- A LAMP assay for the rapid and robust assessment of Wolbachia infection in Aedes aegypti under field and laboratory conditions
- Nonarteritic anterior ischemic optic neuropathy is associated with cerebral small vessel disease
- Fiber-tract localized diffusion coefficients highlight patterns of white matter disruption induced by proximity to glioma
- The fight against polio through the NO-DO newsreels during the Francoism period in Spain
- Ocean sound levels in the northeast Pacific recorded from an autonomous underwater glider
- Cost-consequence analysis of influenza vaccination among the staff of a large teaching hospital in Rome, Italy: A pilot study
- The relationship among the progression of inflammation in umbilical cord, fetal inflammatory response, early-onset neonatal sepsis, and chorioamnionitis
- How medical professional students view older people with dementia: Implications for education and practice
- An enhanced nonparametric EWMA sign control chart using sequential mechanism
- Land use change, carbon stocks and tree species diversity in green spaces of a secondary city in Myanmar, Pyin Oo Lwin
- Is there a difference in women’s experiences of care with medication vs. manual vacuum aspiration abortions? Determinants of person-centered care for abortion services
- Maternal complications in pregnancy and childbirth for women with epilepsy: Time trends in a nationwide cohort
- Adsorption of oxytetracycline on kaolinite
- Interdisciplinary stratified care for low back pain: A qualitative study on the acceptability, potential facilitators and barriers to implementation
- The role of resource transfer in positive, non-additive litter decomposition
- The impact of language on the interpretation of resuscitation clinical care plans by doctors. A mixed methods study
- Quantum dots reveal heterogeneous membrane diffusivity and dynamic surface density polarization of dopamine transporter
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- The heavy metals lead and cadmium are cytotoxic to human bone osteoblasts via induction of redox stress
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- Correction: Change in larval fish assemblage in a USA east coast estuary estimated from twenty-six years of fixed weekly sampling
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- Correction: Transcriptome profiling of mouse brain and lung under Dip2a regulation using RNA-sequencing
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