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Depression increases the risk of rotator cuff tear and rotator cuff repair surgery: A nationwide population-based study


Autoři: Liang-Tseng Kuo aff001;  Hong-Ming Chen aff003;  Pei-An Yu aff001;  Chi-Lung Chen aff001;  Wei-Hsiu Hsu aff001;  Yao-Hung Tsai aff001;  Ko-Jung Chen aff004;  Vincent Chin-Hung Chen aff002
Působiště autorů: Division of Sports Medicine, Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan aff001;  College of Medicine, Chang Gung University, Taoyuan, Taiwan aff002;  Department of Psychiatry, Chang Gung Memorial Hospital, Chiayi, Taiwan aff003;  Health Information and Epidemiology Laboratory, Chang Gung Memorial Hospital, Chiayi, Taiwan aff004
Vyšlo v časopise: PLoS ONE 14(11)
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pone.0225778

Souhrn

Background

Chronic inflammation is known to be associated with both rotator cuff tears (RCTs) and depression. However, no epidemiological studies with a longitudinal follow-up have been performed to prove this association. We aimed to investigate whether depressed patients had an elevated risk of RCT and subsequent repair surgery compared with those without depression.

Methods

This retrospective cohort study comprised of patients diagnosed with depression between 2000 and 2010 (depression cohort) and patients without depression (non-depression cohort, 1:2 age and sex matched). The risk of RCT and rotator cuff repair surgery were determined during a 13-year follow-up (2000–2013) between these two cohorts.

Results

This study included 26,868 patients with depression and 53,736 patients without depression. The incidence of RCT was 648 and 438 per 100,000 person-years in the depression and non-depression cohorts, respectively. The adjusted hazard ratio (HR) was 1.46 (95% confidence interval [CI], 1.36–1.57) for depressed patients. The incidence of rotator cuff repair surgery was 28 and 18 per 100,000 person-years in the depression and non-depression cohorts, respectively. Depressed patients also had a significantly increased risk of subsequent rotator cuff repair surgery (adjusted HR = 1.46; 95% CI, 1.04–2.06).

Conclusion

The present study showed that depression was associated with an increased risk of rotator cuff tear and rotator cuff repair surgery.

Klíčová slova:

Diagnostic medicine – Surgical and invasive medical procedures – Coronary heart disease – Depression – Hyperlipidemia – Inflammatory diseases – Tendons – Surgical repair


Zdroje

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