Illuminating Fungal Infections with Bioluminescence

1. GreerLF3rd, SzalayAA (2002) Imaging of light emission from the expression of luciferases in living cells and organisms: a review. Luminescence 17 : 43–74 doi:10.1002/bio.676

2. AndreuN, ZelmerA, WilesS (2011) Noninvasive biophotonic imaging for studies of infectious disease. FEMS Microbiol Rev 35 : 360–394 doi:10.1111/j.1574-6976.2010.00252

3. RiceBW, CableMD, NelsonMB (2001) In vivo imaging of light-emitting probes. J Biomed Opt 6 : 432–440 doi:10.1117/1.1413210

4. SollDR, SrikanthaT (1998) Reporters for the analysis of gene regulation in fungi pathogenic to man. Curr Opin Microbiol 1 : 400–405 Doi:10.1016/S1369-5274(98)80056-8

5. BrockM (2012) Application of bioluminescence imaging for in vivo monitoring of fungal infections. Int J Microbiol 2012 : 956794 doi:10.1155/2012/956794

6. DoyleTC, NawotkaKA, PurchioAF, AkinAR, FrancisKP, et al. (2006) Expression of firefly luciferase in Candida albicans and its use in the selection of stable transformants. Microb Pathog 40 : 69–81 doi:10.1016/j.micpath.2005.11.002

7. EnjalbertB, RachiniA, VediyappanG, PietrellaD, SpaccapeloR, et al. (2009) A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections. Infect Immun 77 : 4847–4858 doi:10.1128/IAI.00223-09

8. DonatS, HasenbergM, SchäferT, OhlsenK, GunzerM, et al. (2012) Surface display of Gaussia princeps luciferase allows sensitive fungal pathogen detection during cutaneous aspergillosis. Virulence 3 : 51–61 doi:10.4161/viru.3.1.18799

9. SlesionaS, Ibrahim-GranetO, OliasP, BrockM, JacobsenID (2012) Murine infection models for Aspergillus terreus pulmonary aspergillosis reveal long-term persistence of conidia and liver degeneration. J Infect Dis 205 : 1268–1277 doi:10.1093/infdis/jis193

10. GaligerC, BrockM, JouvionG, SaversA, ParlatoM, et al. (2013) Assessment of efficacy of antifungals against Aspergillus fumigatus: value of real-time bioluminescence imaging. Antimicrob Agents Chemother 57 : 3046–3059 doi:10.1128/AAC.01660-12

11. PichlerA, PriorJL, Piwnica-WormsD (2004) Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine. Proc Natl Acad Sci U S A 101 : 1702–1707 doi:10.1073/pnas.0304326101

12. SantosEB, YehR, LeeJ, NikhaminY, PunzalanB, et al. (2009) Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase. Nat Med 15 : 338–344 doi:10.1038/nm.1930

13. DoyleTC, NawotkaKA, KawaharaCB, FrancisKP, ContagPR (2006) Visualizing fungal infections in living mice using bioluminescent pathogenic Candida albicans strains transformed with the firefly luciferase gene. Microb Pathog 40 : 82–90 doi:10.1016/j.micpath.2005.11.003

14. d'EnfertC, VecchiarelliA, BrownAJ (2010) Bioluminescent fungi for real-time monitoring of fungal infections. Virulence 1 : 174–176 doi:10.4161/viru.1.3.11119

15. VecchiarelliA, d'EnfertC (2012) Shedding natural light on fungal infections. Virulence 3 : 15–17 doi:10.4161/viru.3.1.19247

16. BrockM, JouvionG, Droin-BergèreS, DussurgetO, NicolaMA, et al. (2008) Bioluminescent Aspergillus fumigatus, a new tool for drug efficiency testing and in vivo monitoring of invasive aspergillosis. Appl Environ Microbiol 74 : 7023–7035 doi:10.1128/AEM.01288-08

17. PietrellaD, EnjalbertB, ZeidlerU, ZnaidiS, RachiniA, et al. (2012) A luciferase reporter for gene expression studies and dynamic imaging of superficial Candida albicans infections. Methods Mol Biol 845 : 537–546 doi:10.1007/978-1-61779-539-8_39

18. MosciP, PericoliniE, GabrielliE, KennoS, PeritoS, et al. (2013) A novel bioluminescence mouse model for monitoring oropharyngeal candidiasis in mice. Virulence 4 : 250–254 doi:10.1186/1471-2180-10-105

19. Vande VeldeG, KucharíkováS, SchrevensS, HimmelreichU, Van DijckP (2013) Towards non-invasive monitoring of pathogen-host interactions during Candida albicans biofilm formation using in vivo bioluminescence. Cell Microbiol 16 : 115–130 doi:10.1111/cmi.12184

20. Vande VeldeG, KucharíkováS, Van DijckP, HimmelreichU (2014) Bioluminescence imaging of fungal biofilm development in live animals. Methods Mol Biol 1098 : 153–167 doi:10.1007/978-1-62703-718-1_13

21. Ibrahim-GranetO, JouvionG, HohlTM, Droin-BergèreS, PhilippartF, et al. (2010) In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis. BMC Microbiol 10 : 105 doi:10.1186/1471-2180-10-105

22. JouvionG, BrockM, Droin-BergèreS, Ibrahim-GranetO (2012) Duality of liver and kidney lesions after systemic infection of immunosuppressed and immunocompetent mice with Aspergillus fumigatus. Virulence 3 : 43–50 doi:10.4161/viru.3.1.18654

23. PietrellaD, AngiolellaL, VavalaE, RachiniA, MondelloF, et al. (2011) Beneficial effect of Mentha suaveolens essential oil in the treatment of vaginal candidiasis assessed by real-time monitoring of infection. BMC Complement Altern Med 11 : 18 doi:10.1186/1472-6882-11-18

24. PietrellaD, RachiniA, TorosantucciA, ChianiP, BrownAJ, et al. (2010) A beta-glucan-conjugate vaccine and anti-beta-glucan antibodies are effective against murine vaginal candidiasis as assessed by a novel in vivo imaging technique. Vaccine 28 : 1717–1725 doi:10.1016/j.vaccine

25. BranchiniBR, AblamskyDM, DavisAL, SouthworthTL, ButlerB, et al. (2010) Red-emitting luciferases for bioluminescence reporter and imaging applications. Anal Biochem 396 : 290–297 doi:10.1016/j.ab.2009.09.009