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Genetic Architecture of Abdominal Pigmentation in


Body pigmentation contributes to the spectacular biodiversity present in nature and mediates mate choice, mimicry, and physiological functions such as thermoregulation and UV resistance. Thus, pigmentation is a significant contributor to fitness. In order to understand how complex traits such as pigmentation evolve, we must first identify the genetic variants underlying phenotypic variation. We used the Drosophila melanogaster Genetic Reference Panel, a wild derived population of fully sequenced inbred fly lines, to identify the contributions of both known and novel genetic variants to natural variation in abdominal pigmentation in female flies. Our results show that genetic variation within many biological pathways contributes to variation in D. melanogaster pigmentation.


Vyšlo v časopise: Genetic Architecture of Abdominal Pigmentation in. PLoS Genet 11(5): e32767. doi:10.1371/journal.pgen.1005163
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1005163

Souhrn

Body pigmentation contributes to the spectacular biodiversity present in nature and mediates mate choice, mimicry, and physiological functions such as thermoregulation and UV resistance. Thus, pigmentation is a significant contributor to fitness. In order to understand how complex traits such as pigmentation evolve, we must first identify the genetic variants underlying phenotypic variation. We used the Drosophila melanogaster Genetic Reference Panel, a wild derived population of fully sequenced inbred fly lines, to identify the contributions of both known and novel genetic variants to natural variation in abdominal pigmentation in female flies. Our results show that genetic variation within many biological pathways contributes to variation in D. melanogaster pigmentation.


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