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Let's Face It—Complex Traits Are Just Not That Simple


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Vyšlo v časopise: Let's Face It—Complex Traits Are Just Not That Simple. PLoS Genet 10(11): e32767. doi:10.1371/journal.pgen.1004724
Kategorie: Formal Comment
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1004724

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Zdroje

1. ClaesP, LibertonDK, DanielsK, RosanaKM, QuillenEE, et al. (2014) Modeling 3D Facial Shape from DNA. PLoS Genet 10: e1004224.

2. HuD, MarcucioRS (2009) A SHH-responsive signaling center in the forebrain regulates craniofacial morphogenesis via the facial ectoderm. Development 136: 107–116.

3. LiuF, van der LijnF, SchurmannC, ZhuG, ChakravartyMM, et al. (2012) A genome-wide association study identifies five loci influencing facial morphology in Europeans. PLoS Genet 8: e1002932.

4. GrimstonSK, GoldbergDB, WatkinsM, BrodtMD, SilvaMJ, et al. (2011) Connexin43 deficiency reduces the sensitivity of cortical bone to the effects of muscle paralysis. J Bone Miner Res 26: 2151–2160.

5. HumphriesSE, DrenosF, Ken-DrorG, TalmudPJ (2010) Coronary heart disease risk prediction in the era of genome-wide association studies: current status and what the future holds. Circulation 121: 2235–2248.

6. WagnerGP, PavlicevM, CheverudJM (2007) The road to modularity. Nat Rev Genet 8: 921–931.

7. HallgrimssonB, JamniczkyH, YoungNM, RolianC, ParsonsTE, et al. (2009) Deciphering the Palimpsest: Studying the Relationship Between Morphological Integration and Phenotypic Covariation. Evol Biol 36: 355–376.

8. HermissonJ, WagnerGP (2004) The population genetic theory of hidden variation and genetic robustness. Genetics 168: 2271–2284.

9. Martinez-AbadiasN, MitteroeckerP, ParsonsTE, EsparzaM, SjovoldT, et al. (2012) The Developmental Basis of Quantitative Craniofacial Variation in Humans and Mice. Evol Biol 39: 554–567.

10. HeuzeY, SinghN, BasilicoC, JabsEW, HolmesG, et al. (2014) Morphological comparison of the craniofacial phenotypes of mouse models expressing the Apert FGFR2 S252W mutation in neural crest- or mesoderm-derived tissues. Bone 63: 101–109 doi:10.1016/j.bone.2014.03.003

11. YoungNM, ChongHJ, HuD, HallgrimssonB, MarcucioRS (2010) Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape. Development 137: 3405–3409.

12. AttanasioC, NordAS, ZhuY, BlowMJ, LiZ, et al. (2013) Fine tuning of craniofacial morphology by distant-acting enhancers. Science 342: 1241006.

13. HillWG, GoddardME, VisscherPM (2008) Data and theory point to mainly additive genetic variance for complex traits. PLoS Genet 4: e1000008.

14. YangJ, BenyaminB, McEvoyBP, GordonS, HendersAK, et al. (2010) Common SNPs explain a large proportion of the heritability for human height. Nat Genet 42: 565–569.

15. WolfJB, PompD, EisenEJ, CheverudJM, LeamyLJ (2006) The contribution of epistatic pleiotropy to the genetic architecture of covariation among polygenic traits in mice. Evol Dev 8: 468–476.

16. WolfJB, FrankinoWA, AgrawalAF, BrodieED3rd, MooreAJ (2001) Developmental interactions and the constituents of quantitative variation. Evolution Int J Org Evolution 55: 232–245.

17. MitteroeckerP, BooksteinF (2011) Linear Discrimination, Ordination, and the Visualization of Selection Gradients in Modern Morphometrics. Evol Biol 38: 100–114.

18. HammondP, HuttonTJ, AllansonJE, BuxtonB, CampbellLE, et al. (2005) Discriminating power of localized three-dimensional facial morphology. Am J Hum Genet 77: 999–1010.

19. HammondP, HuttonTJ, AllansonJE, CampbellLE, HennekamRC, et al. (2004) 3D analysis of facial morphology. Am J Med Genet A 126A: 339–348.

20. WagnerGP (1996) Homologues, natural kinds and the evolution of modularity. Am Zool 36: 36–43.

Štítky
Genetika Reprodukčná medicína

Článok vyšiel v časopise

PLOS Genetics


2014 Číslo 11
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