Innate Recognition of Fungal Cell Walls

1. BowmanSM

FreeSJ

2006 The structure and synthesis of the fungal cell wall. Bioessays 28 799 808

2. WheelerRT

FinkGR

2006 A drug-sensitive genetic network masks fungi from the immune system. PLoS Pathog 2 e35 doi:10.1371/journal.ppat.0020035

3. LevitzSM

SpechtCA

2006 The molecular basis for the immunogenicity of Cryptococcus neoformans mannoproteins. FEMS Yeast Res 6 513 524

4. LongKH

GomezFJ

MorrisRE

NewmanSL

2003 Identification of heat shock protein 60 as the ligand on Histoplasma capsulatum that mediates binding to CD18 receptors on human macrophages. J Immunol 170 487 494

5. ChaffinWL

2008 Candida albicans cell wall proteins. Microbiol Mol Biol Rev 72 495 544

6. RappleyeCA

EissenbergLG

GoldmanWE

2007 Histoplasma capsulatum α-(1,3)-glucan blocks innate immune recognition by the beta-glucan receptor. Proc Natl Acad Sci U S A 104 1366 1370

7. BanksIR

SpechtCA

DonlinMJ

GerikKJ

LevitzSM

2005 A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans. Eukaryot Cell 4 1902 1912

8. NeteaMG

GowNA

MunroCA

BatesS

CollinsC

2006 Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors. J Clin Invest 116 1642 1650

9. MeansTK

MylonakisE

TampakakisE

ColvinRA

SeungE

2009 Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36. J Exp Med 206 637 653

10. GoodridgeHS

WolfAJ

UnderhillDM

2009 Beta-glucan recognition by the innate immune system. Immunol Rev 230 38 50

11. FerwerdaB

FerwerdaG

PlantingaTS

WillmentJA

van SprielAB

2009 Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections. N Engl J Med 361 1760 1767

12. GlockerE-O

HennigsA

NabaviM

SchafferAA

WoellnerC

2009 A Homozygous CARD9 Mutation in a Family with Susceptibility to Fungal Infections. N Engl J Med 361 1727 1735

13. DanJM

WangJP

LeeCK

LevitzSM

2008 Cooperative stimulation of dendritic cells by Cryptococcus neoformans mannoproteins and CpG oligodeoxynucleotides. PLoS ONE 3 e2046 doi:10.1371/journal.pone.0002046

14. BittencourtVC

FigueiredoRT

da SilvaRB

Mourao-SaDS

FernandezPL

2006 An alpha-glucan of Pseudallescheria boydii is involved in fungal phagocytosis and Toll-like receptor activation. J Biol Chem 281 22614 22623

15. LeeCG

Da SilvaCA

LeeJY

HartlD

EliasJA

2008 Chitin regulation of immune responses: an old molecule with new roles. Curr Opin Immunol

16. BrandhorstTT

WuthrichM

Finkel-JimenezB

WarnerT

KleinBS

2004 Exploiting type 3 complement receptor for TNF-alpha suppression, immune evasion, and progressive pulmonary fungal infection. J Immunol 173 7444 7453

17. MaYJ

DoniA

HummelshojT

HonoreC

BastoneA

2009 Synergy between ficolin-2 and pentraxin 3 boosts innate immune recognition and complement deposition. J Biol Chem 284 28263 28275

18. AimaniandaV

BayryJ

BozzaS

KniemeyerO

PerruccioK

2009 Surface hydrophobin prevents immune recognition of airborne fungal spores. Nature 460 1117 1121

19. HuangH

OstroffGR

LeeCK

WangJP

SpechtCA

2009 Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists. Infect Immun 77 1774 1781

20. Rubin-BejeranoI

AbeijonC

MagnelliP

GrisafiP

FinkGR

2007 Phagocytosis by human neutrophils is stimulated by a unique fungal cell wall component. Cell Host Microbe 2 55 67