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Too Much Cleavage of Cyclin E Promotes Breast Tumorigenesis
article has not abstract
Vyšlo v časopise: Too Much Cleavage of Cyclin E Promotes Breast Tumorigenesis. PLoS Genet 8(3): e32767. doi:10.1371/journal.pgen.1002623
Kategorie: Perspective
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1002623Souhrn
article has not abstract
Zdroje
1. HwangHCClurmanBE 2005 Cyclin E in normal and neoplastic cell cycles. Oncogene 24 2776 2786
2. KeyomarsiKTuckerSLBuchholzTACallisterMDingY 2002 Cyclin E and survival in patients with breast cancer. N Engl J Med 347 1566 1575
3. PorterPLMaloneKEHeagertyPJAlexanderGMGattiLA 1997 Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nat Med 3 222 225
4. LoebKRKostnerHFirpoENorwoodTTsuchiyaKD 2005 A mouse model for cyclin E-dependent genetic instability and tumorigenesis. Cancer Cell 8 35 47
5. MinellaACSwangerJBryantEWelckerMHwangH 2002 p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation. Curr Biol 12 1817 1827
6. HarwellRMPorterDCDanesCKeyomarsiK 2000 Processing of cyclin E differs between normal and tumor breast cells. Cancer Res 60 481 489
7. PorterDCZhangNDanesCMcGahrenMJHarwellRM 2001 Tumor-specific proteolytic processing of cyclin E generates hyperactive lower-molecular-weight forms. Mol Cell Biol 21 6254 6269
8. HarwellRMMullBBPorterDCKeyomarsiK 2004 Activation of cyclin-dependent kinase 2 by full length and low molecular weight forms of cyclin E in breast cancer cells. J Biol Chem 279 12695 12705
9. WingateHPuskasADuongMBuiTRichardsonD 2009 Low molecular weight cyclin E is specific in breast cancer and is associated with mechanisms of tumor progression. Cell Cycle 8 1062 1068
10. AkliSZhengPJMultaniASWingateHFPathakS 2004 Tumor-specific low molecular weight forms of cyclin E induce genomic instability and resistance to p21, p27, and antiestrogens in breast cancer. Cancer Res 64 3198 3208
11. WingateHZhangNMcGarhenMJBedrosianIHarperJW 2005 The tumor-specific hyperactive forms of cyclin E are resistant to inhibition by p21 and p27. J Biol Chem 280 15148 15157
12. AkliSVan PeltCSBuiTMultaniASChangS 2007 Overexpression of the low molecular weight cyclin E in transgenic mice induces metastatic mammary carcinomas through the disruption of the ARF-p53 pathway. Cancer Res 67 7212 7222
13. Bagheri-YarmandRBiernackaAHuntKKKeyomarsiK 2010 Low molecular weight cyclin E overexpression shortens mitosis, leading to chromosome missegregation and centrosome amplification. Cancer Res 70 5074 5084
14. ZhouYJXieYTGuJYanLGuanGX 2011 Overexpression of cyclin E isoforms correlates with poor prognosis in rectal cancer. Eur J Surg Oncol 37 1078 1084
15. CorinIDi GiacomoMCLastellaPBagnuloRGuantiG 2006 Tumor-specific hyperactive low-molecular-weight cyclin E isoforms detection and characterization in non-metastatic colorectal tumors. Cancer Biol Ther 5 198 203
16. DavidsonBSkredeMSilinsIShih IeMTropeCG 2007 Low-molecular weight forms of cyclin E differentiate ovarian carcinoma from cells of mesothelial origin and are associated with poor survival in ovarian carcinoma. Cancer 110 1264 1271
17. BalesEMillsLMilamNMcGahren-MurrayMBandyopadhyayD 2005 The low molecular weight cyclin E isoforms augment angiogenesis and metastasis of human melanoma cells in vivo. Cancer Res 65 692 697
18. DuongMTAkliSWeiCWingateHFLiuW 2012 LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients. PLoS Genet 8 e1002538 doi:10.1371/journal.pgen.1002538
19. AkliSVan PeltCSBuiTMeijerLKeyomarsiK 2011 Cdk2 is required for breast cancer mediated by the low-molecular-weight isoform of cyclin E. Cancer Res 71 3377 3386
20. Nanos-WebbAJabbourNAMultaniASWingateHOumataN 2011 Targeting low molecular weight cyclin E (LMW-E) in breast cancer. Breast Cancer Res Treat E-pub ahead of print 22 June 2011
21. SpruckCSunDFieglHMarthCMueller-HolznerE 2006 Detection of low molecular weight derivatives of cyclin E1 is a function of cyclin E1 protein levels in breast cancer. Cancer Res 66 7355 7360
22. DelkNAHuntKKKeyomarsiK 2009 Altered subcellular localization of tumor-specific cyclin E isoforms affects cyclin-dependent kinase 2 complex formation and proteasomal regulation. Cancer Res 69 2817 2825
23. JackmanMKubotaYden ElzenNHagtingAPinesJ 2002 Cyclin A - and cyclin E-Cdk complexes shuttle between the nucleus and the cytoplasm. Mol Biol Cell 13 1030 1045
24. CarusoJAHuntKKKeyomarsiK 2010 The neutrophil elastase inhibitor elafin triggers rb-mediated growth arrest and caspase-dependent apoptosis in breast cancer. Cancer Res 70 7125 7136
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