Childhood stunting in relation to the pre- and postnatal environment during the first 2 years of life: The MAL-ED longitudinal birth cohort study

1. Black RE, Victora CG, Walker SP, Bhutta ZA, Christian P, de Onis M, et al. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet. 2013;382:427–51. doi: 10.1016/S0140-6736(13)60937-X 23746772

2. Victora CG, Adair L, Fall C, Hallal PC, Martorell R, Richter L, et al. Maternal and child undernutrition: consequences for adult health and human capital. Lancet. 2008;371:340–57. doi: 10.1016/S0140-6736(07)61692-4 18206223

3. Black RE, Allen LE, Bhutta ZA, Caulfield LE, de Onis M, Ezzati M, et al. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet. 2008;371:243–60. doi: 10.1016/S0140-6736(07)61690-0 18207566

4. Kuklina EV, Ramakrishnan U, Stein AD, Barnhart HH, Martorell R. Early childhood growth and development in rural Guatemala. Early Hum Dev. 2006;82:425–33. doi: 10.1016/j.earlhumdev.2005.10.018 16431042

5. Dewey KG, Begum K. Long-term consequences of stunting in early life. Matern Child Nutr. 2011;7:S5–18.

6. Shrimpton R, Victora CG, de Onis M, Lima RC, Blössner M, Clugston G. Worldwide timing of growth faltering: implications for nutritional interventions. Pediatrics. 2001;107:E75. 11331725

7. Victora CG, de Onis M, Hallal PC, Blössner M, Shrimpton R. Worldwide timing of growth faltering: revisiting implications for interventions. Pediatrics. 2010;125:e473–80. doi: 10.1542/peds.2009-1519 20156903

8. United Nations Children’s Fund. Strategy for improved nutrition of children and women in developing countries. New York: United Nations Children’s Fund; 1990.

9. The Malnutrition and Enteric Disease Study (MAL-ED): understanding the consequences for child health and development. Clin Infect Dis. 2014;59(Suppl 4):S193–330. Available from: https://academic.oup.com/cid/issue/59/suppl_4, Accessed 6/15/17.

10. MAL-ED Network Investigators. The MAL-ED study: a multinational and multidisciplinary approach to understand the relationship between enteric pathogens, malnutrition, gut physiology, physical growth, cognitive development, and immune responses in infants and children up to 2 years of age in resource-poor environments. Clin Infect Dis. 2014;59:S193–206. doi: 10.1093/cid/ciu653 25305287

11. Platts-Mills JA, McCormick BJ, Kosek M, Pan WK, Checkley W, Houpt ER. Methods of analysis of enteropathogen infection in the MAL-ED cohort study. Clin Infect Dis. 2014;59:S233–8. doi: 10.1093/cid/ciu408 25305292

12. Houpt E, Gratz J, Kosek M, Zaidi AK, Qureshi S, Kang G, et al. Microbiologic methods utilized in the MAL-ED cohort study. Clin Infect Dis. 2014;59:S225–32. doi: 10.1093/cid/ciu413 25305291

13. Richard SA, Barrett LJ, Guerrant RL, Checkley W, Miller MA, MAL-ED Network Investigators. Disease surveillance methods used in the 8-site MAL-ED cohort study. Clin Infect Dis. 2014;59:S220–4. doi: 10.1093/cid/ciu435 25305290

14. World Health Organization. WHO child growth standards: methods and development. Length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age. Geneva: World Health Organization; 2006.

15. Addo OY, Stein AD, Fall CH, Gigante DP, Guntupalli AM, Horta BL, et al. Maternal height and child growth patterns. J Pediatr. 2013;163:549–54. doi: 10.1016/j.jpeds.2013.02.002 23477997

16. Psaki SR, Seidman JC, Miller M, Gottlieb M, Bhutta ZA, Ahmed T, et al. Measuring socioeconomic status in multicountry studies: results from the eight-country MAL-ED study. Popul Health Metr. 2014;12:8. doi: 10.1186/1478-7954-12-8 24656134

17. Psaki S, Bhutta ZA, Ahmed T, Ahmed S, Bessong P, Islam M, et al. Household food access and child malnutrition: results from the eight-country MAL-ED study. Popul Health Metr. 2012;10:24. doi: 10.1186/1478-7954-10-24 23237098

18. Ambikapathi R, Kosek MN, Lee GO, Mahopo C, Patil CL, Maciel BL, et al. How multiple episodes of exclusive breastfeeding impact estimates of exclusive breastfeeding duration: report from the eight-site MAL-ED birth cohort study. Matern Child Nutr. 2016;12:740–56. doi: 10.1111/mcn.12352 27500709

19. Kosek M, Guerrant RL, Kang G, Bhutta Z, Yori PP, Gratz J, et al. Assessment of environmental enteropathy in the MAL-ED cohort study: theoretical and analytic framework. Clin Infect Dis. 2014;59:S239–47. doi: 10.1093/cid/ciu457 25305293

20. Harrell FE Jr. Regression modeling strategies. New York Springer-Verlag; 2001.

21. Lin DY, Wei LJ. The robust inference for the Cox proportional hazards model. J Amer Stat Assoc. 1989;84:1074–8.

22. Checkley W, Buckley G, Gilman RH, Assis AM, Guerrant RL, Morris SS, et al. Childhood malnutrition and infection network. multi-country analysis of the effects of diarrhea on childhood stunting. Int J Epidemiol. 2008;37:816–30. doi: 10.1093/ije/dyn099 18567626

23. Christian P, Lee SE, Donahue Angel M, Adair LS, Arifeen SE, Ashorn P, et al. Risk of childhood undernutrition related to small-for-gestational age and preterm birth in low- and middle-income countries. Int J Epidemiol. 2013;42:1340–55. doi: 10.1093/ije/dyt109 23920141

24. Lee AC, Katz J, Blencowe H, Cousens S, Kozuki N, Vogel JP, et al. National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010. Lancet Global Health. 2013;1:e26–36. doi: 10.1016/S2214-109X(13)70006-8 25103583

25. Han Z, Lutsiv O, Mulla S, McDonald SD. Maternal height and the risk of preterm birth and low birth weight: a systematic review and meta-analyses. J Obstet Gynaecol Can. 2012;34:721–46. doi: 10.1016/S1701-2163(16)35337-3 22947405

26. World Health Organization. Global nutrition targets 2025: policy brief series. Geneva: World Health Organization; 2014.

27. Garza C, Borghi E, Onyango AW, de Onis M, WHO Multicentre Growth Reference Study Group. Parental height and child growth from birth to 2 years in the WHO Multicentre Growth Reference Study. Matern Child Nutr. 2013;9:58–68. doi: 10.1111/mcn.12085 24074318

28. Puentes E, Wang F, Behrman JR, Cunha F, Hoddinott J, Maluccio JA, et al. Early life height and weight production functions with endogenous energy and protein inputs. Econ Hum Biol. 2016;22:65–81. doi: 10.1016/j.ehb.2016.03.002 27026217

29. Weemaes C, Klasen I, Göertz J, Beldhuis-Valkis M, Olafsson O, Haraldsson A. Development of immunoglobulin A in infancy and childhood. Scand J Immunol. 2003;58(6):642–8. 14636420

30. Steiner TS, Lima AA, Nataro JP, Guerrant RL. Enteroaggregative escherichia coli produce intestinal inflammation and growth impairment and cause interleukin-8 release from intestinal epithelial cells. J Infect Dis. 1998;177:88–96. 9419174

31. Checkley W, Gilman RH, Epstein LD, Suarez M, Diaz JF, Cabrera L, et al. Asymptomatic and symptomatic cryptosporidiosis: their acute effect on weight gain in Peruvian children. Am J Epidemiol. 1997;145:156–63. 9006312

32. Korpe PS, Petri WA. Environmental enteropathy: critical implications of a poorly understood condition. Trends Mol Med. 2012;18:328–36. doi: 10.1016/j.molmed.2012.04.007 22633998

33. The MAL-ED Network Investigators. Causal pathways from enteropathogens to environmental enteropathy: findings from the MAL-ED birth cohort study. EBioMedicine. 2017;18:109–17. doi: 10.1016/j.ebiom.2017.02.024 28396264

34. Charbonneau MR, Blanton LV, DiGiulio DB, Relman DA, Lebrilla CB, Mills DA, et al. A microbial perspective of human developmental biology. Nature. 2016;535:48–55. doi: 10.1038/nature18845 27383979

35. Cole TJ, Parkin JM. Infection and its effect on the growth of young children: a comparison of The Gambia and Uganda. Trans R Soc Trop Med Hyg. 1977;71:196–8. 888165

36. Guerrant RL, Kirchhoff LV, Shields DS, Nations MK, Leslie J, de Sousa MA, et al. Prospective study of diarrheal illnesses in northeastern Brazil: patterns of disease, nutritional impact, etiologies, and risk factors. J Infect Dis. 1983;148:986–97. 6361176

37. Black RE, Brown KH, Becker S. Effects of diarrhea associated with specific enteropathogens on the growth of children in rural Bangladesh. Pediatrics. 1984;73:799–805. 6374599

38. Bairagi R, Chowdhury MK, Kim YJ, Curlin GT, Gray RH. The association between malnutrition and diarrhoea in rural Bangladesh. Int J Epidemiol. 1987;16:477–81. 3667051

39. Borghol N, Suderman M, McArdle W, Racine A, Hallett M, Pembrey M, et al. Associations with early-life socio-economic position in adult DNA methylation. Int J Epidemiol. 2012;41:62–74. doi: 10.1093/ije/dyr147 22422449