Differential Expression of Ecdysone Receptor Leads to Variation in Phenotypic Plasticity across Serial Homologs

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One of the most exquisite types of organismal adaptations in nature occurs when organisms are able to change the way they develop in anticipation of the different selective environments they will experience as adults. This leads to variation in adult morphologies that are adaptive. Environmental cues experienced during development often lead to variation in hormonal titers that can have profound effect on the way genes are regulated and on the adult morphology. Here we examine the hormonal and molecular mechanisms that allow specific traits that are repeated in an organism (butterfly eyespots) to either be sensitive to environmental cues–and develop different morphologies—or insensitive to these cues and develop the same morphology. We discover that a specific gene, a hormone receptor, that is expressed in the sensitive eyespots but absent in the insensitive eyespots, is responsible for regulating the level of sensitivity of each of the eyespots to an environmental cue. We identify a molecule that is regulating levels of environmental sensitivity, or phenotypic plasticity, across repeated traits in an organism.

Vyšlo v časopise: Differential Expression of Ecdysone Receptor Leads to Variation in Phenotypic Plasticity across Serial Homologs. PLoS Genet 11(9): e32767. doi:10.1371/journal.pgen.1005529
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1005529

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