The Long Path from QTL to Gene
article has not abstract
Vyšlo v časopise:
The Long Path from QTL to Gene. PLoS Genet 8(9): e32767. doi:10.1371/journal.pgen.1002975
Kategorie:
Perspective
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.pgen.1002975
Souhrn
article has not abstract
Zdroje
1. EppigJT, BlakeJA, BultCJ, KadinJA, RichardsonJE, et al. (2012) The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse. Nucleic Acids Res 40: D881–D886.
2. DwinellMR, WortheyEA, ShimoyamaM, Bakir-GungorB, DePonsJ, et al. (2009) The Rat Genome Database 2009: variation, ontologies, and pathways. Nucleic Acids Res 37: D744–D749.
3. Weinberg RA (2006) The biology of cancer. New York: Garland Science. 850 p.
4. FarajiF, PangY, WalkerRC, BorgesRN, YangL, HunterKW (2012) Cadm1 is a metastasis susceptibility gene that suppresses metastasis by modifying tumor interaction with the cell-mediated immunity. PLoS Genet 8: e1002926 doi:10.1371/journal.pgen.1002926.
5. DemantP (2003) Cancer susceptibility in the mouse: Genetics, biology and implications for human cancer. Nature Rev Genetics 4 : 721–735.
6. FlintJ, ValdarW, ShifmanS, MottR (2005) Strategies for mapping and cloning quantitative trait genes in rodents. Nature Rev Genetics 6 : 271–286.
7. HunterKW, BromanKW, Le VoyerT, LukesL, CozmaD, et al. (2001) Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1. Cancer Res 61 : 8866–8872.
8. LancasterM, RouseJ, HunterKW (2005) Modifiers of mammary tumor progression and metastasis on mouse chromosomes 7, 9, and 17. Mammalian Genome 16 : 120–126.
9. FrazerKA, EskinE, KangHM, BogueMA, HindsDA, et al. (2007) A sequence-based variation map of 8.27 million SNPs in inbred mouse strains. Nature 448 : 1050–1053.
10. KeaneTM, GoodstadtL, DanecekP, WhiteMA, WongK, et al. (2011) Mouse genomic variation and its effect on phenotypes and gene regulation. Nature 477 : 289–294.
11. ThreadgillDW, ChurchillGA (2012) Ten years of the collaborative cross. G3 2 : 153–156.
12. SvensonKL, GattiDM, ValdarW, WelshCE, ChengR, et al. (2012) High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics 190 : 437–447.
13. LloydKC (2011) A knockout mouse resource for the biomedical research community. Ann NY Acad Sci 1245 : 24–26.
14. GuanC, YeC, YangX, GaoJ (2010) A review of current large-scale mouse knockout efforts. Genesis 48 : 73–85.
15. CuiX, JiD, FisherDA, WuY, BrinerDM, WeinsteinEJ (2011) Targeted integration in rat and mouse embryos with zinc-finger nucleases. Nature Biotechnol 29 : 64–67.
Štítky
Genetika Reprodukčná medicínaČlánok vyšiel v časopise
PLOS Genetics
2012 Číslo 9
- Gynekologové a odborníci na reprodukční medicínu se sejdou na prvním virtuálním summitu
- Je „freeze-all“ pro všechny? Odborníci na fertilitu diskutovali na virtuálním summitu
-
Všetky články tohto čísla
- Heterozygous Mutations in DNA Repair Genes and Hereditary Breast Cancer: A Question of Power
- GWAS of Diabetic Nephropathy: Is the GENIE out of the Bottle?
- The Conflict within and the Escalating War between the Sex Chromosomes
- Proteome-Wide Analysis of Disease-Associated SNPs That Show Allele-Specific Transcription Factor Binding
- Exome Sequencing Identifies Rare Deleterious Mutations in DNA Repair Genes and as Potential Breast Cancer Susceptibility Alleles
- A Gene Family Derived from Transposable Elements during Early Angiosperm Evolution Has Reproductive Fitness Benefits in
- Genome-Wide Association Study for Serum Complement C3 and C4 Levels in Healthy Chinese Subjects
- Role of Transposon-Derived Small RNAs in the Interplay between Genomes and Parasitic DNA in Rice
- Co-Evolution of Mitochondrial tRNA Import and Codon Usage Determines Translational Efficiency in the Green Alga
- SIRT6/7 Homolog SIR-2.4 Promotes DAF-16 Relocalization and Function during Stress
- CNV Formation in Mouse Embryonic Stem Cells Occurs in the Absence of Xrcc4-Dependent Nonhomologous End Joining
- Tetraspanin Is Required for Generation of Reactive Oxygen Species by the Dual Oxidase System in
- Citrullination of Histone H3 Interferes with HP1-Mediated Transcriptional Repression
- Variation in Genes Related to Cochlear Biology Is Strongly Associated with Adult-Onset Deafness in Border Collies
- The Long Non-Coding RNA Affects Chromatin Conformation and Expression of , but Does Not Regulate Its Imprinting in the Developing Heart
- Rif2 Promotes a Telomere Fold-Back Structure through Rpd3L Recruitment in Budding Yeast
- Is a Metastasis Susceptibility Gene That Suppresses Metastasis by Modifying Tumor Interaction with the Cell-Mediated Immunity
- The p38/MK2-Driven Exchange between Tristetraprolin and HuR Regulates AU–Rich Element–Dependent Translation
- Rare Copy Number Variants Contribute to Congenital Left-Sided Heart Disease
- A Genetic Basis for a Postmeiotic X Versus Y Chromosome Intragenomic Conflict in the Mouse
- An Essential Role of Variant Histone H3.3 for Ectomesenchyme Potential of the Cranial Neural Crest
- Characterization of Inducible Models of Tay-Sachs and Related Disease
- Hominoid-Specific Protein-Coding Genes Originating from Long Non-Coding RNAs
- Transcriptional Repression of Hox Genes by HP1/HPL and H1/HIS-24
- Integrative Genomic Analysis Identifies Isoleucine and CodY as Regulators of Virulence
- Convergence of the Transcriptional Responses to Heat Shock and Singlet Oxygen Stresses
- Genomics of Adaptation during Experimental Evolution of the Opportunistic Pathogen
- Enrichment of HP1a on Drosophila Chromosome 4 Genes Creates an Alternate Chromatin Structure Critical for Regulation in this Heterochromatic Domain
- Vsx2 Controls Eye Organogenesis and Retinal Progenitor Identity Via Homeodomain and Non-Homeodomain Residues Required for High Affinity DNA Binding
- The Long Path from QTL to Gene
- TCF7L2 Modulates Glucose Homeostasis by Regulating CREB- and FoxO1-Dependent Transcriptional Pathway in the Liver
- The Non-Flagellar Type III Secretion System Evolved from the Bacterial Flagellum and Diversified into Host-Cell Adapted Systems
- Complex Chromosomal Rearrangements Mediated by Break-Induced Replication Involve Structure-Selective Endonucleases
- Factors That Promote H3 Chromatin Integrity during Transcription Prevent Promiscuous Deposition of CENP-A in Fission Yeast
- A Mimicking-of-DNA-Methylation-Patterns Pipeline for Overcoming the Restriction Barrier of Bacteria
- Determinants of Human Adipose Tissue Gene Expression: Impact of Diet, Sex, Metabolic Status, and Genetic Regulation
- Genome-Wide Association Studies Identify Heavy Metal ATPase3 as the Primary Determinant of Natural Variation in Leaf Cadmium in
- Tethering of the Conserved piggyBac Transposase Fusion Protein CSB-PGBD3 to Chromosomal AP-1 Proteins Regulates Expression of Nearby Genes in Humans
- A Genome-Wide Association Study Identifies Five Loci Influencing Facial Morphology in Europeans
- Normal DNA Methylation Dynamics in DICER1-Deficient Mouse Embryonic Stem Cells
- H4K20me1 Contributes to Downregulation of X-Linked Genes for Dosage Compensation
- The NDR Kinase Scaffold HYM1/MO25 Is Essential for MAK2 MAP Kinase Signaling in
- Coevolution within and between Regulatory Loci Can Preserve Promoter Function Despite Evolutionary Rate Acceleration
- New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes
- SWI/SNF-Like Chromatin Remodeling Factor Fun30 Supports Point Centromere Function in
- A Response Regulator Interfaces between the Frz Chemosensory System and the MglA/MglB GTPase/GAP Module to Regulate Polarity in
- Functional Variants in and Involved in Activation of the NF-κB Pathway Are Associated with Rheumatoid Arthritis in Japanese
- Two Distinct Repressive Mechanisms for Histone 3 Lysine 4 Methylation through Promoting 3′-End Antisense Transcription
- Genetic Modifiers of Chromatin Acetylation Antagonize the Reprogramming of Epi-Polymorphisms
- UTX and UTY Demonstrate Histone Demethylase-Independent Function in Mouse Embryonic Development
- A Comparison of Brain Gene Expression Levels in Domesticated and Wild Animals
- PLOS Genetics
- Archív čísel
- Aktuálne číslo
- Informácie o časopise
Najčítanejšie v tomto čísle
- Enrichment of HP1a on Drosophila Chromosome 4 Genes Creates an Alternate Chromatin Structure Critical for Regulation in this Heterochromatic Domain
- Normal DNA Methylation Dynamics in DICER1-Deficient Mouse Embryonic Stem Cells
- The NDR Kinase Scaffold HYM1/MO25 Is Essential for MAK2 MAP Kinase Signaling in
- Functional Variants in and Involved in Activation of the NF-κB Pathway Are Associated with Rheumatoid Arthritis in Japanese