SOFTWARE PACKAGE FOR ELECTROPHYSIOLOGICAL MODELING OF NEURONAL AND CARDIAC EXCITABLE CELLS

English version České info

The software package described in this article is dedicated for educational and research purposes in the area of electrophysiological cell membrane properties modeling. The designed and created software package offers a selection of several models of nerve fibre membrane, cortical neuron models and various models of heart cells. The model properties and simulation conditions can be set interactively. Consequently, generation of an action potential (AP) on a particular membrane can be observed. The software allows computation and graphical visualization of actual time courses of model state variables, particularly the membrane potential, membrane currents and other model variables. Eventually, additional important characteristics are evaluated from the output data, such as AP duration (APD) of heart cells or AP frequency of cortical neurons.

Keywords:
electrophysiological modeling, software package, neuron, heart cell, cell membrane models, action potential

Autoři: Elena Cocherová ^1,2; Jozef Púčik ¹; Martin Nováček ¹
Působiště autorů: Institute of Electronics and Photonics, FEI STU, Bratislava, Slovak Republic ¹; Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovak Republic ²
Vyšlo v časopise: Lékař a technika - Clinician and Technology No. 2, 2012, 42, 57-60
Kategorie: Conference YBERC 2012

Souhrn

Keywords:
electrophysiological modeling, software package, neuron, heart cell, cell membrane models, action potential

Zdroje

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