MODELING OF CIRCULATION DYNAMICS WITH ACAUSAL MODELING TOOLS


This paper presents an innovative approach to modeling and simulation using acausal modeling tools, which is representative of the modeling language Modelica. This language allows the description of the modeled relationships directly with the equations. Advantages of this approach are demonstrated on the model circulation dynamics by Guyton, Coleman and Grange of the 1972, which is one of the first models of integrated physiological systems of the organism and opened the domain, which is now engaged in the integrative physiology. The introduction of acausal approach and its comparison to previous methods is the scientific contribution of this paper.

Keywords:
Modelica, Guyton, modeling, biomedicine, Dymola


Autoři: Tomáš Kroček 1
Působiště autorů: First Faculty of Medicine, Charles University, Czech Republic 1
Vyšlo v časopise: Lékař a technika - Clinician and Technology No. 2, 2012, 42, 104-107
Kategorie: Conference YBERC 2012

Souhrn

This paper presents an innovative approach to modeling and simulation using acausal modeling tools, which is representative of the modeling language Modelica. This language allows the description of the modeled relationships directly with the equations. Advantages of this approach are demonstrated on the model circulation dynamics by Guyton, Coleman and Grange of the 1972, which is one of the first models of integrated physiological systems of the organism and opened the domain, which is now engaged in the integrative physiology. The introduction of acausal approach and its comparison to previous methods is the scientific contribution of this paper.

Keywords:
Modelica, Guyton, modeling, biomedicine, Dymola


Zdroje

[1] Guyton, A. C., Coleman, T. G., & Grander, H. J. (1972). Circulation: Overall Regulation. Ann. Rev. Physiol. , 41, stránky 13-41.

[2] Jiří Kofránek, Jan Rusz, Marek Mateják: From Guyton's graphic diagram to multimedia simulators for teaching physiology. (Resurection of Guyton's Chart for educational purpose) Proceedings of the Jackson Cardiovascular-Renal Meeting 2008. (Stephanie Lucas Ed,), CD ROM, 11. pp.

[3] Mangourova, V., Ringwood, J., & Van Vliet, B. (2011). Graphical simulation on environments for modelling and simulation on of integrative physiology. Computer Methods and Programs in Biomedicine, volume 102 (3), pp. 295–304

[4] cellML. (2010). Description of Guyton 1992 Full cardiovascular circulation model. [Online] http://models.cellml.org/exposure/cd10322c000e- 6ff64441464f8773ed83/Guyton_Model_1-0.cellml/view

[5] Fritzon, P. (2003). Principles of object-oriented modeling and simulation with Modelica 2.1. Wiley-IEE Press.

[6] Kroček, Tomáš. Implementation of large-scale model of physiological functions in the environment of the language Modelica (in czech). Prague, 2011. Available from: https://cyber.felk.cvut.cz/research/theses/papers/181.pdf. Master thesis. CTU FEE. Supervisor: Doc. MUDr. Jiří Kofránek, CSc.

[7] Jiří Kofránek, Marek Mateják, Pavol Privitzer: Causal or acausal modeling: labour for humans or labour for machines. In Technical Conmputing Prague 2008, 16th Annual Conference Proceedings. (Cleve Moler, Aleš Procházka, Robert bartko, Martin Folin, Jan Houška, Petr Byron Eds). Humusoft s.r.o., Prague, 2008, ISBN 978-80-7080-692-0. CD ROM, str. 1-16, [Online] http://www2.humusoft.cz/kofranek/058_Kofranek.pdf

[8] Jiří Kofránek, Marek Mateják, Pavol Privitzer: HumMod - large scale physiological model in Modelica. Proceedings of 8th. International Modelica conference 2011, Dresden*, internetový sborník (12 stran): https://www.modelica.org/events/modelica2011/Proceedings/pa ges/papers/23_poster_ID_175_a_fv.pdf

[9] Hester R, Brown A, Husband L, Iliescu R, Pruett WA, Summers RL and Coleman T (2011). HumMod: A modeling environment for the simulation of integrative human physiology. Front. Physio. 2:12. doi: 10.3389/fphys.2011.00012

[10] Kofránek, Jiří Privitzer, Pavol, Mateják, Marek, Matoušek, Stanislav: Use of web multimedia simulation in biomedical teaching. In Proceedings of the 2011 International Conference on Frontiers in Education: Computer Science & Computer Engineering, Las Vegas, July 18-21, 2011, (H. R. Arabia, V. A. Cincy, L. Deligianidis, Eds.), ISBN 1-60132-180-5, CSREA Press, Las Vegas, Nevada, 2011, 282-288.

[11] Kofránek, Jiří, Matoušek, Stanislav, Rusz, Jan, Stodulka, Petr, Privitzer, Pavol, Mateják, Marek, Tribula Martin: The Atlas of physiology and pathophysiology: web-based multimedia enabled interactive simulations. Computer Methods and Programs in Biomedicine, 104(2), 143-153, 2011 IF 1.44

Štítky
Biomedicína
Článek Editorial

Článok vyšiel v časopise

Lékař a technika

Číslo 2

2012 Číslo 2

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