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Články
- Časopisy
- Kurzy
- Témy
- Kongresy
- Videa
- Podcasty
The development of connectives in three to five-year-old monolingual Spanish-speaking children
Authors: Francisco J. Rodríguez-Muñoz aff001; Dimitrinka G. Níkleva aff002
Authors place of work: Department of Education, University of Almería, Almería, Spain aff001; Department of Language Education, University of Granada, Granada, Spain aff002
Published in the journal: PLoS ONE 14(10)
Category: Research Article
doi: https://doi.org/10.1371/journal.pone.0224461Summary
Little attention has been paid to the expansion in the use of connectives in children that are acquiring Spanish as a first language. Considering that language structure emerges from language use, naturalistic data were utilised from two conversational corpora. 12 types of connectives showed significant expansion, with the conditional conjunction si ‘if’ presenting the greatest advance, followed by que ‘that’ used as relative pronoun with explicit antecedent and as completive conjunction. We observed that the interordination and subordination relationships progressed more than those of coordination; however, certain connective elements between coordinated constructions displayed a more notable expansion as discourse markers, in the interactional level.
Keywords:
children – Mothers – Language – Grammar – Syntax – Verbal communication – Speech – Phonology
Introduction
There is insufficient attention given to the early language development of Spanish as L1 in the Hispanic academic tradition, which has led to sometimes extreme dependence on Anglo-Saxon work; this is even more striking if one considers that Spanish is the language with the largest number of native speakers in the world [1]. The gap in this type of study has been even more noticeable in the field of constructional development as most of the research on Spanish language acquisition has focused on the phonological component from the eighties (e.g., [2]) until more recently (e.g., [3–5]).
When we refer to constructional development, not forgetting that language development is produced in a block, we situate ourselves at the syntactic level and adopt construction as the basic unit of analysis, which coincides with the definition of complex sentence provided by Diessel [6]; namely, grammatical structures through which specific relationships are expressed between at least two situations in two or more clauses. The term complex construction [7] is related to the constructionist approaches, for which form and function are indissoluble, as is the language of the cognitive and contextual conditions in which it occurs [8].
This study aims to provide new information regarding the elements (prepositions, conjunctions, relative pronouns and discourse markers) that Spanish-speaking children between three - and five-years old use most frequently to join distinct types of syntactic structures or discursive segments. On another note, we understand that the language structure emanates from its use [7, 9–13], so grammar-in-process will be examined through the child’s spontaneous and natural conversation; similarly, the peculiarities of its constructional development will not be described from the grammatic product of the adult, rather that the infantile language is conceived as an autonomous and singular model [10]. In summary, it is assumed that grammatical development is epiphenomenal in character and that advances at the constructional level appear together with specific communication contexts [9, 14–17].
Studies on constructional development in Spanish
In addressing constructional development, three phases associated with specific processes have been distinguished [10, 18]: (1) predication—the use of verbal elements and diversification of forms (tokens), the increase of which correlates with the index of conversational participation; (2) combinatorial—the integration of verbal elements into sequences, which are initially transitive and copulative; and (3) concordance—the use of words with grammatical value and relational in character. Although they can be presented sequentially and have a greater predominance at one time or another, the predication stage, which will have a leading role in the child’s initial grammatical development, does not decline when the phase of combination or concordance emerges; in other words, it is necessary to insist on the elasticity of the grammatical acquisition dynamics.
Of the three previous phases, the one of greatest interest in this work is the last, when there is an increase in the use of elements through which syntactic functions are introduced—connectives—above all, from 3 years onwards. Before this age, it is common for structures to be constructed by connecting lexical elements, ignoring the grammatical ones. At the same time, there is the step of repeating the syntactical schemes learned—through the cutting and pasting system—to manage their own productive patterns; this process has been described as a transition from a semantic grammar, in the initial stages, to a formal grammar, whereby the way the words relate to each other contributes to the comprehension of meaning [7, 19, 20].
Regarding the existing data on the development of grammatical complexity in Spanish, it has been pointed out that complex sentences emerge from 2;6 years [21]. Before using coordinating conjunctions, Spanish-speaking children resort to juxtaposed sentences, which, in adult language, one would expect to be linked by a connective [22]—it has even been said that there is a universal order in languages in which juxtaposition precedes the emergence of connectives [23].
Studies that have examined patterns in acquisition of connectives in Spanish have focused on children at ages between 2 and 4 years. The most widely used connectives in Spanish at the age of 2 and a half are the coordinators y ‘and’ and pero ‘but’. As for subordination, the most frequent class is the relative [24] (for the case of English, see [25]). Although to a lesser extent, the number of incomplete comparative constructions or ellipses is also elevated, and sentences headed by the relative adverb of place (donde ‘where’) without express antecedent, and with ellipses. At 4 years of age, only seven connectives are used [26]: y ‘and’, pero ‘but’, que ‘that’, porque ‘because’, cuando ‘when’, luego ‘then’ and entonces ‘so’, which are completed at ages between 6 and 11 with como ‘like’, o ‘or’, nada más ‘no more’, pues ‘as’, donde ‘where’, despues ‘after’, para ‘for’ and así que ‘so’. The most frequent are y ‘and’, que ‘that’, luego ‘then’ and entonces ‘then/thus’. As for the types of syntactic relationships, at age 4, coordination with y ‘and’ is prevalent, the earliest connective acquired [27], and reduced types of subordination (relative and causal), which will expand from 6 years of age onwards.
Connective or discourse marker? The syntax-pragmatics interface
In language, there are linking resources that can work in different ways within the same domain, the syntactic or the pragmatic, and at the same time in both. We talk, on the one hand, of conjunctions and prepositions that, as syntactic classes, serve to express relations of meaning between the facts denoted by two sentences, and play a central role in the construction of textual coherence [28]. Discourse markers, on the other hand, operate in the pragmatic domain and are used as expressions of relationships between members or discursive segments, speech acts or turns in conversation. However, as van Dijk points out, these elements must be interpreted with respect to pragmatic contexts in terms of function. Thus, the semantic use that is made of sentential connectives must be distinguished from the pragmatic use that corresponds to discourse markers [28], as conceived in this study. This distinction between the semantic and the pragmatic use of connectives and discourse markers has been described in terms of the subjectivity of speaker involvement [29]. Objective relations are defined as content or ideational relations between sentences, while subjective relations are identified with epistemic and speech acts relations [30].
Although the examples provided in (1) and (2) include the same lexical item (porque ‘because’) to express a cause-consequence relationship, they do not act on the same domain. In (1) periods are related because of their propositional content, which depends on their locutionary meaning, i.e., a verbal complement is introduced by a subordinating conjunction. On the contrary, in (2) the first segment reflects a reasoning process where a relationship exists between an event and an inference of the speaker, who is clearly involved. The epistemic use of connectives never appears before its logical meaning in the course of language acquisition [31, 32].
(1) CAELO, 5;1
*CHI: fue a la casa de su abuelita porque su mamá le dijo que fuera.
‘She went to his granny’s because his mom asked her to do it.’
(2) CAELO, 5;7
*CHI: ojalá fuera ya verano, porque en verano no hay cole.
‘I wish it were Summer now, because in Summer there is no school.’
Some of the elements that we analyse in this study are syntactically polycategorial; for example, que ‘that’ in Spanish can be a completive, causal, and even copulative conjunction, while in other sentences, a type of relative pronoun. However, at the same time, y ‘and’, pero ‘but’ or pues ‘as’ belong to the syntactic class of conjunction and, as a result of their decategorisation, they become pragmatic elements, which can carry out additive, counter-argumentative or continuative-type discursive functions, respectively. Therefore, a single unit can belong simultaneously to a syntactic class—conjunctions, prepositions, adverbs, etc. and a pragmatic class—discourse markers [33]. Here, we consider that such elements have undergone a process of pragmaticalisation [34], which determines their use as discourse markers; appropriating, therefore, a “discourse interactional meaning” [35]. The pathway that leads from the first classes to the latter—that is to say, the one that leads to the pragmaticalisation—seems to be the extra-sentential function, from which these units incorporate properties of the discourse markers, such as their mobility in the utterances, their tonicity, the transmission of interpersonal content or the logical-argumentative relations that they carry [36].
In the field that concerns us, one might wonder if there is a comparable evolution between the processes of pragmaticalisation that have been observed in these units within the system and their acquisition in childhood. In other words, are the syntactical functions developed before the pragmatical in the child’s acquisition processes, as is diachronically the case in the linguistic system? Works on language development in English (e.g., [6, 7]) and in Spanish (e.g., [1, 37, 38]) support the idea that these elements firstly unfold pragmatic functions in the interaction, then are later grammaticalized as a syntactic class and perform functions on the sentence plane. This line of research is based on the hypothesis of dependence, support or cohesion with the adult language [39].
Aims of this study
In view of the lack of research in the Hispanic area addressing early constructional development in children—even more so in the contact area between syntax and pragmatics—more descriptive studies are logically needed to account for the genuine characteristics of children’s language in their different evolutive stages.
In particular, this article aims to determine what types of connectives experience a more notable expansion in conversations between Spanish-speaking children and adults from 3 to 5 years of age, as well as identifying the types of syntactic structures that they connect or introduce most frequently. Therefore, the analysis that we propose will, above all, look at the frequency of occurrence.
Conversely, the most significant advance regarding some of the elements analysed will relate to the functions they play in the interaction; that is to say, we anticipate that, at 5 years of age, several will undergo a more significant expansion as discourse markers at the pragmatic level, beyond merely acting as connectives on the syntactical plane. Hence, this study will also attempt to recognise in which elements such a process is observed.
Method
Ethics statement
This study was conducted in accordance with the Declaration of Helsinki and with all the provisions of the human subjects oversight committee guidelines and policies of authors’ institutions (approval code 17-18-1-01C). Ethical permission was granted by the UAL and UGR institutional review boards. Parents and legal guardians provided written informed consent.
Procedure
In accordance with the premises of the modern observational studies on child language acquisition [40], free conversations between children and adults were tape-recorded in two familiar and everyday situations for the child: the domestic context and at school. For both, the researchers were in charge of collecting the material and motivating, in some cases, the conversations by means of spontaneous questions, game situations, graphic support and stories. To provide the most natural interaction, apart from the researcher, whenever possible, there was one or more interlocutor present from the child’s familiar environment where the recordings were made.
Corpus
In order to explore the constructional development of children from 3 to 5 years of age, a corpus was collected from a variety of children at the same age, referring to the similar social condition of all the participants and balancing the samples according to the number of conversational turns analysed.
This research is sourced from two corpora of conversational data: (1) BecaCESNo (Benedet and Snow, dirs.), deposited in the international TalkBank database, and (2) CAELO (‘The Corpus of Spanish oral language learners’), in preparation since September 2018. From the first corpus, 2,114 turns were analysed belonging to 7 children (*CHI) aged between 3;4 and 3;9 years, and 2,111 turns from 6 children between 5;2 and 5;7 years of age. From the second corpus, 2,341 turns from 7 children between 3;5 and 3;10 years of age were examined, and 2,943 turns corresponding to 8 children between 5;1 and 5;7 years of age. The conversational turns of the corpus were spoken segments whose final intonation contour was declarative (.), interrogative (?) or exclamatory (!), as well as independent segments that contained a non-final intonation contour indicating continuation (…). The total number of turns of this type was 9,509.
As for the detection of occurrences in the corpus, within the framework of sentence syntax, we considered elements that act as connectives that separated sentence sets or that introduced constructions. Therefore, connectives that headed groups of words that did not form sentences were not computed. In the pragmatic-interactional framework, the discourse markers that appear in the turns have been analysed, irrespective of whether that turn includes verbs. Likewise, the criterion assumed that the element considered as the discourse marker establishes connectives that exceeded the intra - and intersentence limits; that is to say, the relationships are produced, in such cases, between conversational turns, or within the same turn, between discursive segments. In other words, the discourse markers are differentiated from the connectives in which they are neither integrated in the predicate nor externally modify the sentence, but they link the propositional contents with others that carry the preceding discourse [33].
By codifying connectives and discourse markers, the elements that are repeated immediately in the same turn have been dispensed with. In order to guarantee the reliability of the analysis, the coders considered all the contextual information available to interpret the intra and inter-enunciative relationships of the codified units as specifically as possible.
The transcripts were adapted to the standards of the CHILDES (Child Data Exchange System) project from the TalkBank database and the CHAT coding system (Codes for the Human Analysis of Transcripts) [41]. However, 37 labels were developed for the analysed elements, establishing three levels of subcategorization: plane (syntactic = $SYN; pragmatic = $PRA), category (connective = CN; discourse marker = DM) and subcategory (see Table 1). So, for example, the sequence $SYN:CN:CSCJ corresponds to “syntactic level; connective; causal conjunction”, and $PRA:DM:AD, to a “pragmatic level; discourse marker; additive”.
Tab. 1. Coding scheme and examples for syntactic subcategories. In order to determine the degree to which coders 1 and 2 agree when applying these labels to categories and subcategories, inter-observer reliability was determined via percentage agreement (PA) and weighted kappa (κ) statistics (see Table 2). Results showed that PA was over 90% for both coders and values of k are good (.60-.75) [42].
Tab. 2. Inter-observer reliability values. Participants
As Table 3 shows, 28 monolingual Spanish-speaking children participated in the study. The mean age of the children in the younger age group was 3;7 (3;4–3;10). The mean age of the children in the older age group was 5;4 (5;1–5;7). The two age groups in our study consisted of equal numbers of boys and girls. According to the information provided by parents on the consent form, none of the participants had any known communicative or neurosensory difficulties, nor were they under any pharmacological treatment at the time of data collection. Therefore, they all manifested typical language development. They also belonged to Spanish families with middle socioeconomic status.
Tab. 3. Demographic information about the participants. Analytic plan
Statistical analysis was run on R software version 3.1.3 (Bell Laboratories, New Jersey, NJ, USA). The purpose of the analysis was to compare the proportions (p) of frequency occurrence (n) in relation to the corresponding totals through a descriptive-quantitative and inferential binomial analysis that established the statistical significance of the studied contrasts. As the total of the frequencies was different-not comparable, each frequency was applied to a two-sample z-test to differentiate between proportions, n1 and n2 ≥ 5. Also, a Mann-Whitney-Wilcoxon test was performed to check the existence of statistically significant differences between the group of three-year-olds and the five-year-olds. The significance level was set at p <. 05.
Results
According to the z-test, of the 26 types of identified syntactic elements that function as connectives in the infantile conversations, 12 showed statistically significant differences (46.2%). Likewise, the one-tailed Mann-Whitney-Wilcoxon test determined significant differences between “three-year-old” and “five-year-old” groups in relation to these connectives (p = .032; U = 39.5; z = -1.85). The critical value of U at p < .05 was 42; therefore, the result is significant and the alternative hypothesis (Ha) is accepted according to which there are differences in the usage frequency of the connectives analysed in both groups. This reveals a greater constructional development at 5 years, which corresponds to the similarly greater presence of 11 types of connectives at this age, since the proportion of relative adverbs of place without express antecedent (donde ‘where’) was significantly above that at 3 years of age (see Table 4).
Tab. 4. Connectives between 3 and 5 years of age. The difference in the frequency of use of the following connectives was not significant: final preposition (para ‘for’) (n1 = 132; n2 = 106; z = 1.54); relative adverb of place with explicit antecedent (donde ‘where’) (n1 = 8; n2 = 6; z = .52); relative adverb of mode without explicit antecedent (como ‘like’) (n1 = 36; n2 = 36; z = .00). The following syntactic units were ruled out by the low frequency of use (n1 or n2 < 5): concessive conjunction (aunque ‘although’); illative conjunctive locution (por lo que ‘thus’); consecutive conjunction (tan … que ‘so…that’); exceptive conjunction (menos ‘less’); relative pronoun without explicit antecedent (quien ‘who’); relative time adverb with explicit antecedent (cuando ‘when’); relative adverb of mode with an explicit antecedent (como ‘like’); relative adverb of quantity without an explicit antecedent (cuanto ‘that’); correlative disjunctive conjunction (o … o ‘either…or’); correlative copulative conjunction (ni … ni ‘neither…nor’); and the relative prepositional group (en el que ‘in which’).
Based on the z-value, in Fig 1 the types of connectives are ordered in terms of their greater to lesser incidence at the constructional level, showing a statistically significant frequency increase in the conversations from three to five-year-olds—except for element 12, which experienced a significant drop in use at age 5.
Fig. 1. Distribution of the frequency increase of connectives at the constructional level according to their statistical significance. 1. conditional conj.; 2. relative pron. with explicit antecedent; 3. completive conj.; 4. relative pron. preceded by definite article; 5. relative adv. of time without explicit antecedent; 6. illative conj.; 7. adversative conj.; 8. causal conj.; 9. comparative conj.; 10. disjunctive conj.; 11. copulative conj.; 12. relative adv. of place without explicit antecedent. Completive and copulative conjunctions
Completive and copulative conjunctions are the syntactic categories most frequently used in children’s conversations at both 3 and 5 years of age. While the first type is a mark of nominal subordination, the second one represents a coordinating conjunction that usually denotes that the next sentence contains additional information. Likewise, the increase in the exploitation of these types of connectives at 5 years of age is statistically significant, even more so for completive conjunction than for copulative conjunctions, the latter being less marked. As for the repertoire of units belonging to these categories, in both cases and at both ages, it is very small. However, the type-token ratio is also unable to provide information on the lexical diversity of the speakers, since the Spanish system itself presents a limited inventory for these two syntactic categories; hence, the most common completive conjunction is que ‘that’, the copulative, y ‘and’—with its contextual variant e and negative ni ‘nor’.
With regard to the completive conjunction que ‘that’, it is very common in the analysed conversations that it is preceded by the verb ser ‘to be’ in the third person singular of the present indicative: es que ‘is that’—sometimes in the BecaCESNo corpus, this formula is transcribed as ej que; this reflects a very characteristic phonetic phenomenon of speech in Madrid, which consists of the aspiration of /s/ before a velar consonant. In these cases, the conjunction serves to introduce a sentence as focal information, emphasizing its relevance or contrasting it with information oriented in the opposite direction [33] and can make structures understood of the type (lo que pasa/sucede/ocurre) es que… ‘(what happens/occurs) is that’. Both in these types of copulative constructions as in others, the completive conjunction introduces substantive subordinate sentences in Spanish.
In contrast, the copulative conjunction y ‘and’ serves to unite coordinated sentences; i.e., limbs that do not depend on other syntactic categories, even though it is possible to interpret different nuances, which are distributed in the way observed in Fig 2. In particular, the conjunction y ‘and’ supports the following interpretations in the oral samples of three and five-year-olds:
Additive: The content of the second sentence is in addition to that of the first.
(3) BecaCESNo, 5;2: y = (y) además, (y) también… ‘and = (and) as well as, (and) also…’
*CHI: a_ver, los tiene azules (.) es bajo <y (.) tiene el (.) pelo entre> [/] y tiene el pelo marrón claro
‘Let’s see, he/she has blue eyes (.) is short <and (.) has the (.) hair between> [/] and has light brown hair.’
Illative: The content of the second sentence expresses a consequence derived from that of the first.
(4) BecaCESNo, 5;4: y = por tanto ‘and = therefore’
*CHI: porque no, se ponen el abrigo (.) y se mojan (.) con la lluvia.
‘Because they didn’t put on the coat (.) and they get wet (.) in the rain.’
Adversative: The content of the second sentence contrasts to that of the first.
(5) CAELO, 5;4: y = pero ‘and = but’
*CHI: en mi casa no (es)taba (.) y en la tuya sí.
‘He/She was not in my house (.) and in yours, yes.’
Fig. 2. Frequencies of use of y with additive, illative and adversative values from 3 to 5 years of age, and its increased use as a discourse marker at 5 years of age. As shown in Fig 2, although at 5 years of age there is an increase in frequency with which y ‘and’ is used illatively (z = -.37; p > .05) and adversatively (z = -.37; p > .05), statistical analysis determined significant differences only in relation to the additive value of this conjunction from three to five-years of age (z = -1.89; p < .05). Even so, the most frequent use of y ‘and’ is in the absolute initial position of the turns and, in these cases, it is interpreted as a marker that serves to open the discourse, expressing a continuative value equivalent to other connectives such as pues ‘as’, (y) entonces ‘(and) so’, (y) luego ‘(and) then’, also with an elevated frequency of use in the conversations analysed, in addition to the purely additive (n1 = 266; n2 = 532; z = -6.03; p < .05):
(6) BecaCESNo, 3;7
*CHI: y le destrozó el país y entonces las casitas volvieron a vivir.
‘and tore the country apart and so the cottages lived again.’
*CHI: y entonces colorín colorado (…).
‘and so end of story (…).’
(7) BecaCESNo, 5;5
*CHI: entonces dijo a Caperucita que dónde iba y entonces ella le dijo que a casa de su abuelita y entonces le dijo el lobo que se fuera por el otro pero […].
‘So she told Little Riding Hood where she was going and then she told her to go to her granny's house and then told the Wolf to go for the other but […].’
From these results, it follows that the element y ‘and’ is employed at 3 years of age in a proportionally equated manner as a conjunction and as a discourse marker; However, at 5 years of age, there is a very significant increase in its use having an interactional function on the pragmatic plane, if it is compared with its constructional role as a connective on the syntactic plane (z = -5.97; p < .05).
Other coordinating conjunctions: Disjunctive, adversative and illative
Although there is a significant increase in the use of disjunctive conjunctions from 3 to 5 year of age (z = -3.70; p > .05), it is in relation to adversative (z = -6.19; p > .05) and illative (z = -6.66; p > .05) conjunctions where the most marked increase is observed. In general terms, disjunctive conjunctions are not usual syntactic categories in the conversations analysed when they act as connectives between coordinated sentences. Nor is there a varied repertoire of conjunctions of this type in Spanish: o ‘or’ and its contextual variant u.
Similarly, we do not find simple or complex units (locutions) as alternatives to pero ‘but’ functioning as adversative coordinating conjunctions—sometimes, at 3 years of age, the phonetic variant pelo appears, because the vibrating phonemes are still being acquired. As for illative conjunctions, the inventory is reduced to a single exponent: pues ‘as’ as in the case of disjunctive and adversative conjunctions. Still, it should be remembered that y ‘and’ assumes the functions of pues ‘as’ and, to a lesser extent, pero ‘but’ in the discussions examined.
On the other hand, both in the case of the adversative and the illative connectives, analogous pragmatic functions are identified to those performed by discourse markers in oral interactions. The adversative (pero ‘but’) and concessive (aunque ‘although’) conjunctions find a correlate in the counter-argumentative markers, which operate at the pragmatic level.
As observed by y ‘and’, from 3 to 5 years of age there is a very significant increase in the frequency of use of pero ‘but’ with an interactional function; i.e., as a counter-argumentative discourse marker (n1 = 38; n2 = 304; z = -14.24; p < .05) (Fig 3). If we compare the proportional use of pero ‘but’ as a connective and discourse marker at 5 years of age, the differences are equally significant (z = -5.35; p < .05). In these cases, as in (8), it has interpersonal scope and usually appears in the absolute initial position of the turns, introducing a contrasting movement linked to the immediately preceding turn of an interlocutor.
(8) BecaCESNo, 5;7
*MAR: una toallita de limón, ¿quieres limpia(r)te?
‘A lemon wipe, do you want to clean yourself?’
‘*CHI: pero ¿para qué es?
‘But what is it for?’
*MAR: para cuando comes gambas en las bodas.
‘For when you eat prawns at weddings.’
‘*CHI: pero ¿para qué es el limón?
‘But what's the lemon for?’
Fig. 3. Development of the contrasting expression on the constructional and interactional planes from 3 to 5 years old. A curious phenomenon observed in a few conversations of three-year-olds, as in (9), is that referring to the use of pero ‘but’ as pues ‘well’; i.e., as a discourse marker on a continuative basis. This may be because pero ‘but’ is acquired in isolated cases, before pues ‘well’; which would imply it would assume its discursive function.
(9) BecaCESNo, 3;4: pero = pues ‘but = well’
*PAT: ¿no has escrito la carta todavía?
‘Haven’t you written the letter yet?’
*CHI: <pero no>.
‘< but no >.’
The exceptionality of the previous example is confirmed by the already extraordinary development by the age of 3 of the continuative function on the interactional plane, which also undergoes a significant increase in frequency of use at 5 years of age (n1 = 232; n2 = 444; z = -8.34; p < .05). When comparing the proportional use of pues ‘well’ with the syntactic value in the constructional plane, and that corresponding to its pragmatic value in the interactional plane, we realize that, at 5 years of age, there is an absolute prevalence of the second type (z = -16.68; p < .05). This function is mainly carried out by the discourse markers of y ‘and’, pues ‘as’, entonces ‘so’ and luego ‘then’.
As Fig 4 shows, the early development of pues ‘as’ with a discursive function contrasts with its low productivity on the constructional plane at 3 and 5 years of age, as an illative conjunction that, in our conversations, does not alternate with any other exponent—only the phonetic variants pos and p(u)es are recorded.
Fig. 4. Development of the expression of illation/continuity on the constructional and interactional planes from 3 to 5 years of age. Other subordinate conjunctions: conditional, causal and comparative
According to our data, there is significant development from 3 to 5 years of age at the constructional level to establish conditional (z = -11.29), causal (z = -6.14) and comparative (z = -4.39) relationships, in that order, using subordinate conjunctions in conversations.
The most characteristic connective that heads conditional constructions in Spanish is si ‘if’, as in the oral interactions we analysed. In these cases, on the one hand, the conditional clause (protasis) often precedes the conditioned clause (apodosis) and, on the other, other particles appear (y ‘and’, o ‘or’, pero ‘but’, porque ‘because’, pues ‘as’) before the connective si ‘if’.
The connective that typically introduces causal constructions in Spanish coincides with the most common in the conversations analysed: porque ‘because’—with phonetic variants: po(r)que, polque—. As for the repertoire of causal connectives, together with porque, at 3 years of age que ‘that’ (24.42%), como ‘like’ (4.65%) and pues ‘as’ (1.16%) are used, while at 5 years of age, como ‘like’ (23.23%) and que ‘that’ (7.1%). Through the conjunctions that alternate with porque ‘because’, external causals to the verbal predicate are usually constructed, also called explicit causals as they often provide a justification that the speaker infers about the context; i.e., the cause from which a conclusion is expressed about something that is not found in that utterance but in the enunciation.
Causals headed by que ‘because’ and pues ‘as’ are always postponed, whilst those headed by como ‘like’ come before; moreover, they are all external to the predicate and explicit in character. In terms of informativity, in the former, the information is shown as an unfamiliar justification (10), whereas in the latter, the information is presented as if it were already known (11). Apart from this, the causals introduced by que ‘because’ tend to be preceded by an imperative (for related theory with English adverbials, see [43] and [44]).
(10) BecaCESNo, 3;7
*CHI: cuéntamelo tú (.) que yo no sé las letras.
‘You tell me (.) because I don't know the letters.’
(11) BecaCESNo, 3;4
*CHI: como se han monta(d)o to(do)s (.) han tenido que segá [*] la calle y se han queda(d)o en la calle.
%err: segá = cerrar $PHO
‘As they have put up everything (.) they have had to close [*] the street and have stayed in the street.’
Porque ‘because’ is used to introduce both internal and external causalities to the predicate, and the causal constructions headed by that connective may either come before or after; despite this, in the samples, this element usually occupies the initial margin of the children's reactive turns, as in (12), and serves to answer questions with por que ‘why’, something that does not allow external causals.
(12) BecaCESNo, 5;2
*INT: ¿por qué?
‘Why?’
*CHI: porque me llaman Monicaca.
‘Because they call me Monicaca.’
Finally, we look at the constructions that establish quantitative relationships. These are classified according to the quantifiers that form them in a) comparatives of superiority, b) comparatives of equality, and c) comparatives of inferiority. In these constructions, we distinguish between quantitative groups and comparative complements introduced by que ‘that’ and como ‘like’. At 3 years of age, these constructions are very unusual in the samples analysed; of the 6 that we identify, there are equality (tan … como ‘so… that’: 50%) and superiority (más … que ‘more…than’; mayor que ‘greater than’: 50%). In (13) mayor ‘greater’ does not function as a comparative but is considered an adjective in a positive degree since it is combined with the más ‘more’ quantifier.
(13) BecaCESNo, 3;4
*CHI: más mayo(r) que yo.
‘Older than me.’
The increase in the frequency of use of these types of constructions at 5 years of age is significant; they are distributed as follows:
Superiority comparatives (53.1%): más… que ‘more than’.
Equality comparatives (34.4%): lo mismo que ‘the same as’, el mismo que ‘the same as’ and igual que ‘the same as’.
Inferiority comparatives (12.5%): menos … que ‘less … than’.
Also, at the age of 5, there are ponderative consecutive constructions that are absent in the conversations of three-year-old children, whose outline is analogous to that of the comparatives. In all the examples that we find, as in (14) and (15), there is a repeat of the quantifying group, either by the determinant that heads it, or of the whole group; from a pragmatic perspective, this implies a double intensification of that utterance because it is self-ponderative (indicating that an extreme degree of something has been achieved) and is reinforced by repetition:
(14) BecaCESNo, 5;7
*CHI: había una vez un zapatero tan pobre (.) tan pobre (.) que no podía comprar más cuero para hacer zapatos.
‘There once was a shoemaker so poor (.) so poor (.) that he couldn’t buy more leather to make shoes.’
(15) BecaCESNo, 5;8
*CHI: este era un hombre tan (.) tan (.) tan (.) tan gordo (.) que su &esto estómago le llegaba hasta lios [*] pies.
%err: lios = los
‘This man was so (.) so (.) so (.) so fat (.) that his &this stomach touched his [*] feet.’
Relative pronouns and adverbs
Of all the connectives that introduce relative sentences in Spanish, there are only 4 that significantly progress from 3 to 5 years of age; namely: 1) the relative pronoun with explicit antecedent; 2) the relative pronoun without explicit antecedent headed by the definite article; 3) the relative adverb of place without explicit antecedent; and 4) the relative adverb of time without explicit antecedent.
In all cases, they introduce subordinate sentences; those headed by a relative pronoun with an explicit or incorporated antecedent, as in (16) and may act as a noun complement; conversely, those that do not have an explicit antecedent but are headed by a definite article, also called semi-free relatives, can perform various functions, such as being the subject (17) or direct complement (18).
(16) BecaCESNo, 3;7
*CHI: era una vez una barquita de una enanita que vivía en un país muy lejano con los reyes […]
‘There was once a small boat of a dwarf that lived in a very distant country with the king and queen […].’
(17) BecaCESNo, 5;4
*CHI: por ejemplo (.) las que se visten de monjas (.) hacen miedo a todas las niñas (.) y eso tampoco.
‘For example (.) those who dress up as nuns (.) scare all the girls (.) and not that either.’
(18) BecaCESNo, 3;6
*CHI: <el cuando> [//] ya sé lo que quieres hacel [*] para entlal [*] en mi casa quieres comelme [*].
%err: hacel = hacer $PHO; entlal = entrar $PHO; comelme = comerme $PHO
‘When I know what you want to do [*] to enter my house, you want to eat me [*].’
Relative subordinates that have no explicit antecedents, also called free relatives can be introduced both by pronouns and relative adverbs. Those showing a significant expansion in the conversations we analyzed from 3 to 5 years of age are only those introduced by cuando ‘when’, and function as an adjunct or time circumstantial (19); thus, when the relative adverb donde ‘where’ introduces a clause functioning as an adjunct or place circumstantial, as in (20), instead of observing greater exploitation of these types of structures at 5 years of age, a significant drop in use occurs compared to at 3 years of age:
(19) BecaCESNo, 5;8
*CHI: yo me cabreo cuando las cosas no se pueden hacer.
‘I get angry when things can't be done.’
(20) CAELO, 3;5
*CHI: y vino uno donde estaba yo.
‘And one came where I was.’
Discussion
Interordination and subordination vs. coordination from 3 to 5 years of age
In contrast to subordinate conjunctions, such as the completive que ‘that’ which introduces subordinate clauses dependent on another syntactic category that they complement or modify, the coordinative conjunctions, such as the copulative y, unite independent sentence conjuncts which do not depend on other categories. Generally speaking, the types of sentences that advance or expand more from 3 to 5 years of age are those that are associated with interordination and subordination. However, it is advisable to note certain nuances regarding these types of structures present quite different properties amongst themselves:
Conditional constructions, typically introduced by the conjunction si ‘if’, are those that experience the most significant frequency increase at 5 years of age. These are major (regular) structures that do not modify the predicate; instead the two periods that integrate them (conditioning and conditioned) maintain an interdependent relationship (or interordination) so the conditional constructions are considered sentence complements, external or peripheral.
Sentences headed by relative pronouns with an explicit antecedent (que ‘that’), which are the second type whose frequency increases more significantly at 5 years of age; they are subordinates that modify the preceding segment (antecedent), with which they maintain an anaphoric relationship, so that the relative exerts a subordinate connection when introducing a clause as a dependent sentence. Relative semi-free sentences are also considered subordinate, those that are headed by the definite article plus a relative pronoun—they are the fourth whose frequency increases most significantly at 5 years of age.
Sentences introduced by a completive conjunction (que ‘that’), the third type that progresses most significantly at 5 years of age in terms of frequency of use in conversation. These are also subordinate (substantive, completive or declarative) and they perform the same functions as nouns or nominal groups.
Only starting from the sixth position out of the twelve we have established coordinating conjunctions appear; their use, as in the case of subordinates, increasing significantly in statistical frequency at 5 years of age: the illatives—analyzed by some grammarians as subordinate links [see 33]—the adversatives, the disjunctives and, finally, the copulatives. Also, in the second sextile are those conjunctions that head causal constructions, which, as in the case of conditionals, are sometimes interpreted as peripheral complements—this is the case for the external causals—although at other times, they can function as adjuncts or circumstantials—when the causal sentence is internal to the predicate and subordinate to it.
Constructional development in Spanish linked to the expansion of connectives from 3 to 5 years of age
After analysing the 12 connectives in the oral interactions of the 28 children, the syntactic category found to advance most from 3 to 5 years of age is the conjunction si ‘if’, which appears in major sentences structures headed by conditional constructions.
With regard to the relative structures (S1-wh-S2), it has been pointed out that the function that first develops the wh-forms in complex sentences is complementation (i.e., a relative sentence without an antecedent), whereas the function of relativization (i.e., a relative sentence with an antecedent) would be posterior [45]. According to our data, at 3 years of age, there is a similar trend in Spanish; i.e., relative sentences without an explicit antecedent (n = 160) are proportionally higher than those constructed with an antecedent (n = 118) (z = -2.67; p < .05). However, the analysis of spontaneous conversation samples reveals a very notable expansion of relative sentences with an explicit antecedent (relativization) from 3 to 5 years of age, the second syntactic category in terms of advancing most at these ages.
On the other hand, the first two types of sentences used by children in Spanish are the direct complement subordinates without a connective (Quiero ir al parque ‘I want to go to the park’) and the coordinatives with y ‘and’ [21]. The relative subordinates, of which we have already mentioned the causal, the temporal and the direct complements introduced by que that appear later, between 2 and 3 years of age; however, the development of the latter is not completed until the age of 5 [46]. According to our data, the completive conjunction is the third syntactic category that experiences the most expansion from 3 to 5 years of age, although it does not only introduce direct complement subordinate sentences.
Referring ourselves to the acquisition of English as a first language, the results of our analysis of y coincide with that of Bloom et al. [45], where the first syntactic connective produced by children from 2 to 3 years of age is and, the equivalent of y in Spanish. Taking into account the polyfunctional character of this syntactic-pragmatic element, they establish the following sequence for the emergence of the semantic values corresponding to those ages: 1) additive, 2) temporal, 3) causal, and 4) adversative. In the interactions analysed, the additive value of the copulative conjunction also predominates, followed by the illative conjunction, which relates to the temporal value of posteriority and to consequence—and lastly an adversative value is attributed.
For Peterson and McCabe [47], y is not initially an “all-purpose connective” that progressively gives way to other more specific connectives through which the same semantic relationships are expressed by the copulative conjunction. However, in our analysis, this intuition is confirmed to some extent. So, while y ‘and’ is the connective that experiences the least expansion from 3 to 5 years of age of all those analysed, the increase in the use of the adversative conjunction pero ‘but’ and the illative pues ‘as’ is proportionally greater, despite the fact that, as noted above, the use of y ‘and’ also increases. Both the results of the naturalistic and the experimental studies correspond in that the additive relationships are acquired before the causal ones and, consequently, the additive connectives emerge before the causal connectives [48].
With regard to pues ‘as’, in the samples examined by Aguado [24] and Idiázabal [49] at 2;6 years and between 1;11 and 3;2 years, respectively, no use is recorded. Enríquez [1] dates the emergence of pues at 3;1 years, but only records its use up until 4 years of age as a discourse marker, not as a conjunction. Lastly, it has been pointed out that the subordinate conjunction porque ‘because’, linked to the causal expression, is not fully controlled until 4 years of age [23]. Porque ‘because’ functions more like “a wild card” or “a form of responding” at 2 and a half years than as the introducing connective of a subordinate [24]; in fact, in the interactions analysed, it tends to act as a marginal element that heads reactive turns. In other words, its production is not usually spontaneous, rather the adult gives the child the pattern in the interactions by explicitly asking something using the sequence por que ‘why’, which would function as a key or discursive guideline determining the use of porque ‘because’. The truly causal relationships that are produced spontaneously by the child have been identified in Spanish from the age of 6 [26]. Nonetheless, in our analysis, porque ‘because’ undergoes a fairly significant expansion from 3 to 5 years of age.
Syntactic function vs. pragmatic function: the transcategorical elements
As has been demonstrated, some of the elements analysed that behave as connectives in the constructional level, and experience a notable expansion from 3 to 5 years of age, also increase their interactional functions in a very significant way at 5 years of age—y, which acts as an additive-continuative discourse marker; pero ‘but’, which assumes counter-argumentative functions in the conversation; and pues ‘as’, which has a continuative role equivalent to that of adverbs that are pragmaticalized in the same way, such as entonces ‘so’ or luego ‘then’, with the special presence in narrative sequences of autobiographical episodes based on experiences and personal memories, and in others pertaining to learnt classic stories that are reproduced in conversations (e.g., The three little piggies, Little Red Riding Hood, etc.).
The frequent combination of y ‘and’ as a discourse marker with other markers such as entonces ‘so’ or luego ‘then’ is also commented on in relation to and, which may appear along with then (and then …) [45]. The use of the discourse marker with an additive-continuative value is recurrent even within the same turn and is associated primarily with narrative sequences; this recursion of the marker has been considered a characteristic of child language and has been interpreted as a pragmatic intensification strategy [26]. The use of pues ‘as’ on the interactional plane also coincides often with the additive-continuative corresponding to y ‘and’. This type of pues ‘well’ has been labelled as a commentator, a discursive starter marker and an explanation [1].
As for pero ‘but’, our results confirm those of Varela [50] in children aged between 2 and 4 years, who established its origin in the interaction; i.e., its use in infantile speech emanates from an essentially dialogic process and from collaborative co-construction with the adult. Thus, this often corresponds to a responsive function that logically transcends the sentence plane: following the turn initiated by an adult interlocutor, the child reacts to what was said using the counter-argumentative marker pero ‘but’, which introduces a contrasting movement in the form of objection.
On the other hand, although this study has analysed the sequence es que ‘is that’ as the combination of the copulative verb immobilized in the third person (es ‘is’) and the completive conjunction (que ‘that’) [33], other authors have considered that the formula is fixed and pragmaticalized; therefore, at the argumentative level, it would constitute a justification-type discourse marker [51], which would require the presence of a previous utterance. Likewise, at the informative level, it acts as a focuser while, in other cases, as an intensification mechanism [52].
When pragmatic functions are identified for the analysed elements; that is to say, whenever they are considered discursivised, these are usually located at the initial margin of the turns, either preceded by some other particle or in the absolute initial position—in other cases, as when y acts as an additive-continuative in narrative sequences, it may appear after a pause in the same turn. This increase in frequency of pragmatic functions is particularly marked at the age of 5 when using pues ‘well’ in oral interactions.
In summary, those elements that can carry out both syntactic and pragmatic functions, which we have called transcategorial, show more pronounced development of the latter function between 3 and 5 years of age, although there are also examples recorded in which they act as coordinative conjunctions, in the case of y ‘and’, pero ‘but’ and pues ‘as’, or subordinates, in the case of que ‘that’. However, they are usually present in the absolute initial position of the turns and establish logical-argumentative relationships that are additive(-continuative) (y ‘and’), counter-argumentative (pero ‘but’) and continuative (pues ‘as’) in type, on the one hand; and justificative (es que ‘is that’), on the other. Therefore, our results support the hypothesis of dependence with the adult language [39] and are aligned with those of other authors for whom the pragmatic functions of these transcategorical elements precede the syntactic functions, which are deployed a posteriori in the acquisition process [1, 37, 38, 50]. In other words, in contrast to the tendency observed diachronically in the linguistic system, where first the syntactic functions develop and then extrasententially one arrives at the pragmatic functions, in the development of the language, the child firstly resorts to these elements for interactive and interpersonal purposes, and then gives them grammatical value—the child grammaticalizes them. Therefore, the pragmatic-discursive functionality precedes the purely constructional.
Conclusion
From the analysis of the children’s spontaneous speech, the present study has dealt with expansion rather than emergence (as is more usual in the bibliography) of connectives from 3 to 5 years of age in Spanish. Accordingly, it has been shown that the expression of conditionality using bipolar constructions headed by si ‘if’ is the one showing the greatest expansion, followed by the relative que ‘that’ with antecedent and the completive conjunction que ‘that’. Therefore, it has been verified that, from 3 to 5 years of age, the interdependent (or interordinational) and dependent (or subordinate) relationships between structures increase.
It has also been shown that those transcategorical elements capable of operating simultaneously on two planes, the syntactic and the pragmatic, such as y ‘and’, pero ‘but’ or pues ‘as’, continue to show greater productivity at the interactional level, such as discourse markers, than at the purely grammatical level. As has been pointed out, before being used as conjunctions, they correspond to interactional functions, based on items and patterns learnt in a specific context that can later be imitated and reproduced, which the child will have to recover and extrapolate to comparable communicative situations.
Finally, in the future, it would be advisable to more profoundly investigate the syntagmatic-discursive dynamics in which such elements are produced as those analysed here; for example, after initial labelling, to which this work gives account, it would be possible to establish the relationships between the codified units and the position that they occupy in the utterances, which can be linked to specific informative functions such as focalisation, or to certain types of turns (initiative, reactive, etc.) or speech acts, amongst other things. Likewise, it seems necessary to more profoundly investigate, along with others, development during the infantile period of those elements in Spanish that are adverbial in character, which can act as discourse markers and as modalizers of various kinds on the interactional plane.
Supporting information
S1 Appendix [pdf]
CHAT codes.
Zdroje
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Článok vyšiel v časopisePLOS One
Najčítanejšie tento týždeň
2019 Číslo 10- Metamizol jako analgetikum první volby: kdy, pro koho, jak a proč?
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- Increased incidence of age-related macular degeneration in sensorineural hearing loss: A population-based cohort study
- Evaluating the foundations that help avert antimicrobial resistance: Performance of essential water sanitation and hygiene functions in hospitals and requirements for action in Kenya
- Effects of a hot ambient operating theatre on manual dexterity, psychological and physiological parameters in staff during a simulated burn surgery
- Introduction of quality management in a National Reference Laboratory in Germany
- Histopathological investigation of complex gill disease in sea farmed Atlantic salmon
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- Cognitive impairment in multiple sclerosis: An exploratory analysis of environmental and lifestyle risk factors
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- Interaction of detergents with biological membranes: Comparison of fluorescence assays with filtration protocols and implications for the rates of detergent association, dissociation and flip-flop
- Potential causes of early death among admitted newborns in a rural Tanzanian hospital
- Identification of glomerular and podocyte-specific genes and pathways activated by sera of patients with focal segmental glomerulosclerosis
- Prevalence and correlates of partner violence among adolescent girls and young women: Evidence from baseline data of a cluster randomised trial in Tanzania
- Development of an integrated fingerstick blood self-collection device for radiation countermeasures
- Concordance between gene expression in peripheral whole blood and colonic tissue in children with inflammatory bowel disease
- Effects of arthroscopic vs. mini-open rotator cuff repair on function, pain & range of motion. A systematic review and meta-analysis
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- Hyperglycemia in the early stages of type 1 diabetes accelerates gastric emptying through increased networks of interstitial cells of Cajal
- Nanoaperture fabrication via colloidal lithography for single molecule fluorescence analysis
- A rapid, low pH, nutrient stress, assay to determine the bactericidal activity of compounds against non-replicating Mycobacterium tuberculosis
- Sialochemical analysis in polytraumatized patients in intensive care units
- The black sheep effect: The case of the deviant ingroup robot
- No relationship between fornix and cingulum degradation and within-network decreases in functional connectivity in prodromal Alzheimer’s disease
- Implementation of an international standardized set of outcome indicators in pregnancy and childbirth in Kenya: Utilizing mobile technology to collect patient-reported outcomes
- Breastfeeding support through wet nursing during nutritional emergency: A cross sectional study from Rohingya refugee camps in Bangladesh
- Does route matter? Impact of route of oxytocin administration on postpartum bleeding: A double-blind, randomized controlled trial
- Research on OpenCL optimization for FPGA deep learning application
- Drug therapy problems, medication adherence and treatment satisfaction among diabetic patients on follow-up care at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
- Quality of life and symptom intensity over time in people with cancer receiving palliative care: Results from the international European Palliative Care Cancer Symptom study
- The dynamics of Early Celtic consumption practices: A case study of the pottery from the Heuneburg
- Safety and efficacy of artesunate-amodiaquine combined with either methylene blue or primaquine in children with falciparum malaria in Burkina Faso: A randomized controlled trial
- “Cementing” marriages through childbearing in subsequent unions: Insights into fertility differentials among first-time married and remarried women in Ghana
- Single session high definition transcranial direct current stimulation to the cerebellum does not impact higher cognitive function
- The contribution of age structure to the international homicide decline
- Genetic structure of Mexican lionfish populations in the southwest Gulf of Mexico and the Caribbean Sea
- A physiological dose of oral vitamin B-12 improves hematological, biochemical-metabolic indices and peripheral nerve function in B-12 deficient Indian adolescent women
- Nutritional status, cognitive achievement, and educational attainment of children aged 8-11 in rural South India
- Costs and cost-effectiveness analyses of mCARE strategies for promoting care seeking of maternal and newborn health services in rural Bangladesh
- Cause-specific mortality in the general population with transient dipstick-proteinuria
- Assessing hand dysfunction in cervical spondylotic myelopathy
- KETOS: Clinical decision support and machine learning as a service – A training and deployment platform based on Docker, OMOP-CDM, and FHIR Web Services
- Variation in activity rates may explain sex-specific dorsal color patterns in Habronattus jumping spiders
- Adjusting for spatial variation when assessing individual-level risk: A case-study in the epidemiology of snake-bite in Sri Lanka
- Acute sprint exercise transcriptome in human skeletal muscle
- Parenting and personality disorder: An overview and meta-synthesis of systematic reviews
- Female rats release a trapped cagemate following shaping of the door opening response: Opening latency when the restrainer was baited with food, was empty, or contained a cagemate
- Multiplex communities and the emergence of international conflict
- The impact of socioeconomic status on emergency department outcome in a low-income country setting: A registry-based analysis
- Effect of psycho-social support by teachers on improving mental health and hope of adolescents in an earthquake-affected district in Nepal: A cluster randomized controlled trial
- A cluster-randomized controlled trial of the effectiveness of the JUMP Math program of math instruction for improving elementary math achievement
- Transgenic mouse model for conditional expression of influenza hemagglutinin-tagged human SLC20A1/PIT1
- Use of rapid Model for End-Stage Liver Disease (MELD) increases for liver transplant registrant prioritization after MELD-Na and Share 35, an evaluation using data from the United Network for Organ Sharing
- Fishery Improvement Projects as a governance tool for fisheries sustainability: A global comparative analysis
- QRStree: A prefix tree-based model to fetal QRS complexes detection
- Fundraising and vote distribution: A non-equilibrium statistical approach
- Evaluation of PRRSv specific, maternally derived and induced immune response in Ingelvac PRRSFLEX EU vaccinated piglets in the presence of maternally transferred immunity
- Gene expression profiling of whole blood: A comparative assessment of RNA-stabilizing collection methods
- Alteration of adipose tissue immune cell milieu towards the suppression of inflammation in high fat diet fed mice by flaxseed oil supplementation
- Isoniazid preventive therapy: Uptake, incidence of tuberculosis and survival among people living with HIV in Bulawayo, Zimbabwe
- P16 methylation increases the sensitivity of cancer cells to the CDK4/6 inhibitor palbociclib
- Using long-term datasets to assess the impacts of dietary exposure to neonicotinoids on farmland bird populations in England
- Genetic mapping of distal femoral, stifle, and tibial radiographic morphology in dogs with cranial cruciate ligament disease
- Optimized bioluminescence analysis of adenosine triphosphate (ATP) released by platelets and its application in the high throughput screening of platelet inhibitors
- Consumer beliefs about healthy foods and diets
- An observational study on intracutaneous sodium storage in intensive care patients and controls
- Recovery when you are on your own: Slow population responses in an isolated marine reserve
- How does the method change what we measure? Comparing virtual reality and text-based surveys for the assessment of moral decisions in traffic dilemmas
- Is recent Afghanistan survey data suitable for fertility analysis? A regional investigation based on fertility inhibiting determinants
- Analytical validation of the Target Selector ctDNA platform featuring single copy detection sensitivity for clinically actionable EGFR, BRAF, and KRAS mutations
- Comparison of two swept-source optical coherence tomography biometers and a partial coherence interferometer
- Removal of anthracycline cytostatics from aquatic environment: Comparison of nanocrystalline titanium dioxide and decontamination agents
- A social media intervention to improve nutrition knowledge and behaviors of low income, pregnant adolescents and adult women
- Detection of vision and /or hearing loss using the interRAI Community Health Assessment aligns well with common behavioral vision/hearing measurements
- E-MOVIE - Experimental MOVies for Induction of Emotions in neuroscience: An innovative film database with normative data and sex differences
- Does self-reported pregnancy loss identify women at risk of an adverse cardiovascular phenotype in later life? Insights from UK Biobank
- An elevated glycemic gap predicts adverse outcomes in diabetic patients with necrotizing fasciitis
- 40-Hz auditory steady-state responses and the complex information processing: An exploratory study in healthy young males
- Highly diverse anaerobe-predominant vaginal microbiota among HIV-infected pregnant women in Zambia
- Decision-based models of the implementation of interventions in systems of healthcare: Implementation outcomes and intervention effectiveness in complex service environments
- Dual number-based variational data assimilation: Constructing exact tangent linear and adjoint code from nonlinear model evaluations
- Ultra-deep sequencing reveals pre-mRNA splicing as a sequence driven high-fidelity process
- Use of IoT sensing and occupant surveys for determining the resilience of buildings to forest fire generated PM2.5
- Classification of neurons in the adult mouse cochlear nucleus: Linear discriminant analysis
- Lek-associated movement of a putative Ebolavirus reservoir, the hammer-headed fruit bat (Hypsignathus monstrosus), in northern Republic of Congo
- Attenuation correction using 3D deep convolutional neural network for brain 18F-FDG PET/MR: Comparison with Atlas, ZTE and CT based attenuation correction
- Differences in macular capillary parameters between healthy black and white subjects with Optical Coherence Tomography Angiography (OCTA)
- Sealing agent reduces formation of single and dual-species biofilms of Candida albicans and Enterococcus faecalis on screw joints at the abutment/implant interface
- Chitotetraose activates the fungal-dependent endosymbiotic signaling pathway in actinorhizal plant species
- What is the optimum time for initiation of early mobilization in mechanically ventilated patients? A network meta-analysis
- Cognitive aptitude, peers, and trajectories of marijuana use from adolescence through young adulthood
- Early mortality after diagnosis of cancer of the head and neck – A population-based nationwide study
- Accuracy and interobserver-agreement of respiratory rate measurements by healthcare professionals, and its effect on the outcomes of clinical prediction/diagnostic rules
- Does task delegation to non-physician health professionals improve quality of diabetes care? Results of a scoping review
- The Univariate Flagging Algorithm (UFA): An interpretable approach for predictive modeling
- Profiles and trajectories of impaired social cognition in people with Prader-Willi syndrome
- Effect of pimobendan on physical fitness, lactate and echocardiographic parameters in dogs with preclinical mitral valve disease without cardiomegaly
- Sub-types of safety behaviours and their effects on social anxiety disorder
- Engaging in prosocial behavior explains how high self-control relates to more life satisfaction: Evidence from three Chinese samples
- Artificial fingerprints for cross-comparison of forensic DNA and protein recovery methods
- The organization of Golgi in Drosophila bristles requires microtubule motor protein function and a properly organized microtubule array
- Direct and moderating effects of environmental regulation intensity on enterprise technological innovation: The case of China
- Prevalence and associated factors of depression among Korean adolescents
- Transcriptome analysis of PK-15 cells in innate immune response to porcine deltacoronavirus infection
- Geographic variation in cardiometabolic risk distribution: A cross-sectional study of 256,525 adult residents in the Illawarra-Shoalhaven region of the NSW, Australia
- Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury
- Lipid profile changings after switching from rilpivirine/tenofovir disoproxil fumarate/emtricitabine to rilpivirine/tenofovir alafenamide/emtricitabine: Different effects in patients with or without baseline hypercholesterolemia
- A feature selection strategy for gene expression time series experiments with hidden Markov models
- Dissociating the sequential dependency of subjective temporal order from subjective simultaneity
- Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis
- Population-based estimates of engagement in HIV care and mortality using double-sampling methods following home-based counseling and testing in western Kenya
- Vaginal temperature as indicative of thermoregulatory response in Nellore heifers under different microclimatic conditions
- Galectin-9 gene (LGALS9) polymorphisms are associated with rheumatoid arthritis in Brazilian patients
- The association of brightness with number/duration in human newborns
- Microslit on a chip: A simplified filter to capture circulating tumor cells enlarged with microbeads
- Integrating continuous differential evolution with discrete local search for meander line RFID antenna design
- The impact of the French soda tax on prices and purchases. An ex post evaluation
- Development and validation of monoclonal antibodies against N6-methyladenosine for the detection of RNA modifications
- Structural characterization of a novel polysaccharide from Sargassum thunbergii and its antioxidant and anti-inflammation effects
- Potential biomarker identification for Friedreich’s ataxia using overlapping gene expression patterns in patient cells and mouse dorsal root ganglion
- Major drug resistance mutations to HIV-1 protease inhibitors (PI) among patients exposed to PI class failing antiretroviral therapy in São Paulo State, Brazil
- Chile (Capsicum annuum) plants transformed with the RB gene from Solanum bulbocastanum are resistant to Phytophthora capsici
- Outcomes of acute coronary syndrome patients with concurrent extra-cardiac vascular disease in the era of transradial coronary intervention: A retrospective multicenter cohort study
- Analysis of gene co-expression networks of phosphate starvation and aluminium toxicity responses in Populus spp.
- Risk factors associated with IgA vasculitis with nephritis (Henoch–Schönlein purpura nephritis) progressing to unfavorable outcomes: A meta-analysis
- The prediction model of suicidal thoughts in Korean adults using Decision Tree Analysis: A nationwide cross-sectional study
- A multidimensional understanding of prosperity and well-being at country level: Data-driven explorations
- Factors associated with muscle mass in community-dwelling older people in Singapore: Findings from the SHIELD study
- The prevalence and risk of non-infectious comorbidities in HIV-infected and non-HIV infected men attending general practice in Australia
- Vibrio cholerae strains with inactivated cqsS gene overproduce autoinducer-2 which enhances resuscitation of dormant environmental V. cholerae
- Myocardial function in patients with anomalous left coronary artery from the pulmonary artery syndrome: A long-term speckle tracking echocardiographic study
- Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo
- Joint distribution for number of crossings and longest run in independent Bernoulli observations. The R package crossrun
- Learning to play badminton altered resting-state activity and functional connectivity of the cerebellar sub-regions in adults
- Children’s dietary diversity and related factors in Rwanda and Burundi: A multilevel analysis using 2010 Demographic and Health Surveys
- Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson’s disease
- Precluding rare outcomes by predicting their absence
- Tidal inlet seafloor changes induced by recently built hard structures
- A further study on Franciscobasis Machado & Bedê, 2016 (Odonata: Coenagrionidae), a newly described genus from Minas Gerais, Brazil
- Associative responses to visual shape stimuli in the mouse auditory cortex
- Extracellular matrix turnover and inflammation in chemically-induced TMJ arthritis mouse models
- LRP receptors in chondrocytes are modulated by simulated microgravity and cyclic hydrostatic pressure
- Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases
- Separating the effects of temperature and carbon allocation on the diel pattern of soil respiration in the different phenological stages in dry grasslands
- Unweaving tangled mortality and antibiotic consumption data to detect disease outbreaks – Peaks, growths, and foresight in swine production
- Factors associated with exclusive breast-feeding: A cross-sectional survey in Kaiyuan, Yunnan, Southwest China
- The Model of Mortality with Incident Cirrhosis (MoMIC) and the model of Long-term Outlook of Mortality in Cirrhosis (LOMiC)
- Burden of treatment-resistant depression in Medicare: A retrospective claims database analysis
- Genomic characterisation of perinatal Western Australian Streptococcus agalactiae isolates
- Sharing the filmic experience - The physiology of socio-emotional processes in the cinema
- A super-SILAC based proteomics analysis of diffuse large B-cell lymphoma-NOS patient samples to identify new proteins that discriminate GCB and non-GCB lymphomas
- Pneumoproteins are associated with pulmonary function in HIV-infected persons
- Tissue-specific expression of IgG receptors by human macrophages ex vivo
- Electrical impedance myography for the detection of muscle inflammation induced by λ-carrageenan
- Clustering of the structures by using “snakes-&-dragons” approach, or correlation matrix as a signal
- Asymmetric valuation of gains and losses in effort-based decision making
- Genomic and metabolic differences between Pseudomonas putida populations inhabiting sugarcane rhizosphere or bulk soil
- Method comparison for N-glycan profiling: Towards the standardization of glycoanalytical technologies for cell line analysis
- Gender linked fate explains lower legal abortion support among white married women
- L-3,3’,5-triiodothyronine and pregnenolone sulfate inhibit Torpedo nicotinic acetylcholine receptors
- eQTL mapping of rare variant associations using RNA-seq data: An evaluation of approaches
- Cell fishing: A similarity based approach and machine learning strategy for multiple cell lines-compound sensitivity prediction
- Macrogeographic genetic structure of Lutzomyia longipalpis complex populations using Next Generation Sequencing
- Dual-career through the elite university student-athletes’ lenses: The international FISU-EAS survey
- Machine learning prediction of emesis and gastrointestinal state in ferrets
- Impact of bitter tastant sub-qualities on retronasal coffee aroma perception
- Head orientation and electrode placement potentially influence fetal scalp ECG waveform
- Clinical outcomes associated with the use of the NexSite hemodialysis catheter with new exit barrier technology: Results from a prospective, observational multi-center registry study
- Geospatial correlates of early marriage and union formation in Ghana
- Disruption of white matter connectivity in chronic obstructive pulmonary disease
- Integrated evaluation of clinical, pathological and radiological prognostic factors in squamous cell carcinoma of the lung
- Saliva enhances infection of gingival fibroblasts by herpes simplex virus 1
- Pyk2-dependent phosphorylation of LSR enhances localization of LSR and tricellulin at tricellular tight junctions
- An alternative approach for estimating the number needed to treat for survival endpoints
- Bilirubin reduces visceral obesity and insulin resistance by suppression of inflammatory cytokines
- Can telemedicine initiative be an effective intervention strategy for improving treatment compliance for pediatric HIV patients: Evidences on costs and improvement in treatment compliance from Maharashtra, India
- Trial registration as a safeguard against outcome reporting bias and spin? A case study of randomized controlled trials of acupuncture
- Multi-disciplinary interventions for chronic pain involving education: A systematic review
- Impact of climate change on the integrity of the superstructure of deteriorated U.S. bridges
- Switching to bedaquiline for treatment of rifampicin-resistant tuberculosis in South Africa: A retrospective cohort analysis
- Efficacy of Lactobacillus-supplemented triple therapy for H. pylori eradication: A meta-analysis of randomized controlled trials
- Testing gene by community disadvantage moderation of sexual health outcomes among urban women
- The impact of leishmaniasis on mental health and psychosocial well-being: A systematic review
- Evaluation of a screening algorithm using the Strengths and Difficulties Questionnaire to identify children with mental health problems: A five-year register-based follow-up on school performance and healthcare use
- Optimized fast GPU implementation of robust artificial-neural-networks for k-space interpolation (RAKI) reconstruction
- The cost of illness and economic burden of endometriosis and chronic pelvic pain in Australia: A national online survey
- Refined distributed emotion vector representation for social media sentiment analysis
- Enhancing timeliness of drug overdose mortality surveillance: A machine learning approach
- A real-time gesture recognition system using near-infrared imagery
- Alcohol use and its association with sexual risk behaviors in the Armed Forces of the Republic of the Congo
- Improved survival rates in patients with H1N1 acute respiratory failure in Korea between 2009 and 2016
- Electroencephalographic features of discontinuous activity in anesthetized infants and children
- Tumor stromal type is associated with stromal PD-L1 expression and predicts outcomes in breast cancer
- Mutant prevention concentration of ozenoxacin for quinolone-susceptible or -resistant Staphylococcus aureus and Staphylococcus epidermidis
- The Echobot: An automated system for stimulus presentation in studies of human echolocation
- Evaluation of clinical manifestations, health risks, and quality of life among women with polycystic ovary syndrome
- Magnetic resonance imaging presentation of deep infiltrating endometriosis nodules before and after pregnancy: A case series
- Agrobacterium tumefaciens-mediated transformation of a hevein-like gene into asparagus leads to stem wilt resistance
- Effect of a Mentor Mother Programme on retention of mother-baby pairs in HIV care: A secondary analysis of programme data in Uganda
- Utilizing multiplex fluor LAMPs to illuminate multiple gene expressions in situ
- Genetic relationships between the RACK1 homolog cpc-2 and heterotrimeric G protein subunit genes in Neurospora crassa
- Is latent tuberculosis infection challenging in Iranian health care workers? A systematic review and meta-analysis
- A comparison of the risk of congestive heart failure-related hospitalizations in patients receiving hemodialysis and peritoneal dialysis - A retrospective propensity score-matched study
- A tailored approach to fusion transcript identification increases diagnosis of rare inherited disease
- Experiences, needs, and preferences for follow-up after stroke perceived by people with stroke and healthcare professionals: A focus group study
- Iodine supplementation of lactating women and assessment of infant visual information processing and maternal and infant thyroid function: A randomized trial
- The Nordic Maintenance Care Program: Does psychological profile modify the treatment effect of a preventive manual therapy intervention? A secondary analysis of a pragmatic randomized controlled trial
- Within-subject variability in human retinal nerve fiber bundle width
- Motivation for alcohol consumption or abstinence during pregnancy: A clinical-qualitative study in Brazil
- Comparison of conventional BLUP and single-step genomic BLUP evaluations for yearling weight and carcass traits in Hanwoo beef cattle using single trait and multi-trait models
- Do cognitive and non-cognitive abilities mediate the relationship between air pollution exposure and mental health?
- Molecular phylogeny and morphology reveal a new epiphytic species of Habenaria (Orchidaceae; Orchideae; Orchidinae) from Nepal
- Nitrogen nutrition is a key modulator of the sugar and organic acid content in citrus fruit
- Understanding variation in health service coverage and maternal health outcomes among districts in Rwanda – A qualitative study of local health workers’ perceptions
- Biased cognition in East Asian and Western cultures
- Physical fitness and physical self-concept of male and female young adults in Qatar
- Robust policy evaluation from large-scale observational studies
- Improved semi-supervised autoencoder for deception detection
- Delineation of high resolution climate regions over the Korean Peninsula using machine learning approaches
- Are spasticity, weakness, selectivity, and passive range of motion related to gait deviations in children with spastic cerebral palsy? A statistical parametric mapping study
- ProphET, prophage estimation tool: A stand-alone prophage sequence prediction tool with self-updating reference database
- Conspicuous and cryptic reef fishes from a unique and economically important region in the northern Red Sea
- Time scale of resilience loss: Implications for managing critical transitions in water quality
- Effectiveness of physical and cognitive-behavioural intervention programmes for chronic musculoskeletal pain in adults: A systematic review and meta-analysis of randomised controlled trials
- Relationship between feed efficiency indexes and performance, body measurements, digestibility, energy partitioning, and nitrogen partitioning in pre-weaning dairy heifers
- Long-stay patients in pediatric intensive care unit: Diagnostic-specific definition and predictors
- Evidence of ritual breakage of a ground stone tool at the Late Natufian site of Hilazon Tachtit cave (12,000 years ago)
- Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease
- A systematic review and thematic synthesis of Canada’s LGBTQ2S+ employment, labour market and earnings literature
- The occurrence of ‘Sleeping Beauty’ publications in medical research: Their scientific impact and technological relevance
- Analysis of the protein composition of the spindle pole body during sporulation in Ashbya gossypii
- Assessing undergraduate student and faculty views on animal research: What do they know, whom do they trust, and how much do they care?
- The views and experiences of general dental practitioners (GDP’s) in West Yorkshire who used the International Caries Detection and Assessment System (ICDAS) in research
- Compare HIV/syphilis infections between age groups and explore associated factors of HIV/syphilis co-infections among men who have sex with men in Shenzhen, China, from 2009 to 2017
- Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers
- Effect of exclusive breastfeeding cessation time on childhood morbidity and adverse nutritional outcomes in Ethiopia: Analysis of the demographic and health surveys
- Dual antiplatelet therapy in patients with cirrhosis and acute myocardial infarction – A 13-year nationwide cohort study
- Relationships between electrolyte and amino acid compositions in sweat during exercise suggest a role for amino acids and K+ in reabsorption of Na+ and Cl- from sweat
- A simplified vocal tract model for articulation of [s]: The effect of tongue tip elevation on [s]
- Management and glycemic control of patients with type 2 diabetes mellitus at primary care level in Kedah, Malaysia: A statewide evaluation
- Anabolic steroids among resistance training practitioners
- Factors associated with unsafe abortion practices in Nepal: Pooled analysis of the 2011 and 2016 Nepal Demographic and Health Surveys
- New methods of removing debris and high-throughput counting of cyst nematode eggs extracted from field soil
- Vehicle configurations associated with anatomical-specific severe injuries resulting from traffic collisions
- What has reproductive health decision-making capacity got to do with unintended pregnancy? Evidence from the 2014 Ghana Demographic and Health Survey
- Circulating levels of CD34+ cells predict long-term cardiovascular outcomes in patients on maintenance hemodialysis
- Penetration of linezolid into bone tissue 24 h after administration in patients with multidrug-resistant spinal tuberculosis
- Prosthesis design of animal models of periprosthetic joint infection following total knee arthroplasty: A systematic review
- Coherent diversification in corporate technological portfolios
- Technology opportunity discovery by structuring user needs based on natural language processing and machine learning
- Effect of tranexamic acid administration on acute traumatic coagulopathy in rats with polytrauma and hemorrhage
- Factors associated with the use of diet and the use of exercise for prostate cancer by long-term survivors
- Congenital Zika Syndrome in a Brazil-Paraguay-Bolivia border region: Clinical features of cases diagnosed between 2015 and 2018
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- Malawian children with uncomplicated and cerebral malaria have decreased activated Vγ9Vδ2 γδ T cells which increase in convalescence
- Predictors of mortality within the first year of initiating antiretroviral therapy in urban and rural Kenya: A prospective cohort study
- The investment case as a mechanism for addressing the NCD burden: Evaluating the NCD institutional context in Jamaica, and the return on investment of select interventions
- Design, synthesis, and structural elucidation of novel NmeNANAS inhibitors for the treatment of meningococcal infection
- Bringing fear into focus: The intersections of HIV and masculine gender norms in Côte d’Ivoire
- Scientific output scales with resources. A comparison of US and European universities
- Transplanted spleen stromal cells with osteogenic potential support ectopic myelopoiesis
- Effect of host genotype and Eimeria acervulina infection on the metabolome of meat-type chickens
- Gravity influences bevacizumab distribution in an undisturbed balanced salt solution in vitro
- Agrobacterium tumefaciens-mediated transformation and expression of GFP in Ascochyta lentis to characterize ascochyta blight disease progression in lentil
- Proteomic changes of aryl hydrocarbon receptor (AhR)-silenced porcine granulosa cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
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- Improving the forecasting performance of temporal hierarchies
- Prevalence of surgically correctable conditions among children in a mixed urban-rural community in Nigeria using the SOSAS survey tool: Implications for paediatric surgical capacity-building
- Relatives’ attachment anxiety mediates the association between perceived loss and expressed emotion in early psychosis
- The impact of PEPFAR transition on HIV service delivery at health facilities in Uganda
- Impact of peri-intraventricular haemorrhage and periventricular leukomalacia in the neurodevelopment of preterms: A systematic review and meta-analysis
- Correction: Activation of aryl hydrocarbon receptor signaling by a novel agonist ameliorates autoimmune encephalomyelitis
- Macrophage PPAR-γ suppresses long-term lung fibrotic sequelae following acute influenza infection
- Determination of factors affecting medication adherence in type 2 diabetes mellitus patients using a nationwide claim-based database in Japan
- Beyond the metabolic syndrome: Visceral and marrow adipose tissues impair bone quantity and quality in Cushing’s disease
- Clade II Candida auris possess genomic structural variations related to an ancestral strain
- Effect of aging on the association between ankle muscle strength and the control of bipedal stance
- Dietary polyphenols as a safe and novel intervention for modulating pain associated with intervertebral disc degeneration in an in-vivo rat model
- Kinematic and electromyographic analysis of variations in Nordic hamstring exercise
- Comparison of transcriptomes of an orthotospovirus vector and non-vector thrips species
- Trabeculectomy followed by phacoemulsification versus trabeculectomy alone: The Collaborative Bleb-Related Infection Incidence and Treatment Study
- Whole genome resequencing of watermelons to identify single nucleotide polymorphisms related to flesh color and lycopene content
- Religious practices and long-term survival after hospital discharge for an acute coronary syndrome
- Behavioral recovery and spinal motoneuron remodeling after polyethylene glycol fusion repair of singly cut and ablated sciatic nerves
- Platelets modulate multiple markers of neutrophil function in response to in vitro Toll-like receptor stimulation
- Comparative characterization of bacterial communities in geese consuming of different proportions of ryegrass
- Temperature sensitivity patterns of carbon and nitrogen processes in decomposition of boreal organic soils – Quantification in different compounds and molecule sizes based on a multifactorial experiment
- Cows painted with zebra-like striping can avoid biting fly attack
- The intriguing effect of ethanol and nicotine on acetylcholine-sensitive potassium current IKAch: Insight from a quantitative model
- The accumulation of deficits approach to describe frailty
- Botulinum toxin A injection into the entopeduncular nucleus improves dynamic locomotory parameters in hemiparkinsonian rats
- Turing complete neural computation based on synaptic plasticity
- Influence of mydriasis on optical coherence tomography angiography imaging in patients with age-related macular degeneration
- Specialized care improves outcomes for patients with cirrhosis who require general surgical operations
- Association between plural legal systems and sexual and reproductive health outcomes for women and girls in Nigeria: A state-level ecological study
- 3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster
- Utility of qSOFA and modified SOFA in severe malaria presenting as sepsis
- Correction: Perspectives of general dental practitioners on preventive, patient-centred, and evidence-based oral healthcare—A Q-methodology study
- Early detection and differential serodiagnosis of Mycoplasma hyorhinis and Mycoplasma hyosynoviae infections under experimental conditions
- No evidence of associations between ADHD and event-related brain potentials from a continuous performance task in a population-based sample of adolescent twins
- Antibiotic resistance of blood cultures in regional and tertiary hospital settings of Tyrol, Austria (2006-2015): Impacts & trends
- Simultaneous cardiac and respiratory inhibition during seizure precedes death in the DBA/1 audiogenic mouse model of SUDEP
- Dopamine receptor antagonists effects on low-dimensional attractors of local field potentials in optogenetic mice
- Cell-free DNA levels of twins and sibling pairs indicate individuality and possible use as a personalized biomarker
- Dinosaur ichnology and sedimentology of the Chignik Formation (Upper Cretaceous), Aniakchak National Monument, southwestern Alaska; Further insights on habitat preferences of high-latitude hadrosaurs
- Mechanical effects of MitraClip on leaflet stress and myocardial strain in functional mitral regurgitation – A finite element modeling study
- Catastrophic factors involved in road accidents: Underlying causes and descriptive analysis
- Seroprevalence of anti-Toxoplasma gondii antibodies in wild boars (Sus scrofa), hunting dogs, and hunters of Brazil
- Detection and determination of stability of the antibiotic residues in cow’s milk
- Neural minimization methods (NMM) for solving variable order fractional delay differential equations (FDDEs) with simulated annealing (SA)
- Maternal and perinatal outcomes among women with hypertensive disorders in pregnancy in Kumasi, Ghana
- Characteristics and costs in adults with acute poisoning admitted to the emergency department of a university hospital in Belgium
- War pact model of shrinking networks
- Treatment outcomes based on radiation therapy fields for bifocal germinoma: Synchronous or disseminated disease?
- Effect of an intensive 3-day social cognitive treatment (can do treatment) on control self-efficacy in patients with relapsing remitting multiple sclerosis and low disability: A single-centre randomized controlled trial
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- Postural changes in optic nerve and optic nerve sheath diameters in postural orthostatic tachycardia syndrome and spontaneous intracranial hypotension: A cohort study
- Attitudes and referral practices for pre-exposure prophylaxis (PrEP) among HIV rapid testers and case managers in Philadelphia: A mixed methods study
- The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study
- Endovascular therapy of direct dural carotid cavernous fistulas – A therapy assessment study including long-term follow-up patient interviews
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- An extinction event in planktonic Foraminifera preceded by stabilizing selection
- Optimal seismic retrofitting techniques for URM school buildings located in the southwestern Iberian peninsula
- The effect of a hiding box on stress levels and body weight in Dutch shelter cats; a randomized controlled trial
- Early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: A systematic review and meta-analysis
- Deep brain activation patterns involved in virtual gait without and with a doorway: An fMRI study
- Infant dietary intake of yogurt and cheese and gastroenteritis at 1 year of age: The Japan Environment and Children’s Study
- Attenuation of renal fibrosis after unilateral ureteral obstruction in mice lacking the N-type calcium channel
- Anesthesia during deployment of a military forward surgical unit in low income countries: A register study of 1547 anesthesia cases
- CsBZIP40, a BZIP transcription factor in sweet orange, plays a positive regulatory role in citrus bacterial canker response and tolerance
- Differences in perceived popularity and social preference between bullying roles and class norms
- Identity and pathogenicity of some fungi associated with hazelnut (Corylus avellana L.) trunk cankers in Oregon
- Fermented cereal-based Munkoyo beverage: Processing practices, microbial diversity and aroma compounds
- Associations between focus constructions and levels of exhaustivity: An experimental investigation of Chinese
- Measurement invariance tests of revisions to archaically worded items in the Mach IV scale
- Give science and peace a chance: Speeches by Nobel laureates in the sciences, 1901-2018
- The effect of food anticipation on cognitive function: An eye tracking study
- Adaptation of H3N2 canine influenza virus to feline cell culture
- A meta-analysis of crop response patterns to nitrogen limitation for improved model representation
- Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer’s mouse model are associated with hippocampal synaptic deficits in an age-dependent manner
- Does antibiotic use accelerate or retard cutaneous repair? A systematic review in animal models
- Transforming growth factor beta 1 induces methylation changes in lung fibroblasts
- Hepatic disease and the risk of mortality of Vibrio vulnificus necrotizing skin and soft tissue infections: A systematic review and meta-analysis
- Diagnostic accuracy of midkine on hepatocellular carcinoma: A meta-analysis
- Phosphorus-mediated alleviation of aluminum toxicity revealed by the iTRAQ technique in Citrus grandis roots
- Grouping of complex substances using analytical chemistry data: A framework for quantitative evaluation and visualization
- Management strategies for vaccinated animals after an outbreak of foot-and-mouth disease and the impact on return to trade
- RNA-Seq analysis reveals an essential role of tyrosine metabolism pathway in response to root-rot infection in Gerbera hybrida
- SpliceHetero: An information theoretic approach for measuring spliceomic intratumor heterogeneity from bulk tumor RNA-seq
- Large-scale phylogenomic analysis suggests three ancient superclades of the WUSCHEL-RELATED HOMEOBOX transcription factor family in plants
- Plasma sCD36 as non-circadian marker of chronic circadian disturbance in shift workers
- A cross sectional comparison of drug use indicators using WHO methodology in primary level hospitals participating in an Auditable Pharmaceutical Transactions and Services program versus non-APTS primary hospitals in Southern Ethiopia
- Trends in NBA and Euroleague basketball: Analysis and comparison of statistical data from 2000 to 2017
- Liquid biopsies for omics-based analysis in sentinel mussels
- Reporting biases in self-assessed physical and cognitive health status of older Europeans
- Trends in the characteristics of acute primary angle closure in Korea over the past 10-years
- Obesity-associated insulin resistance adversely affects skin function
- First-line treatments in EGFR-mutated advanced non-small cell lung cancer: A network meta-analysis
- In vivo human lower limb muscle architecture dataset obtained using diffusion tensor imaging
- Tobacco smoke exposure as a risk factor for human papillomavirus infections in women 18-26 years old in the United States
- The trigger-information-response model: Exploring health literacy during the first six months following a kidney transplantation
- Factors influencing the behaviour and perceptions of Australian veterinarians towards antibiotic use and antimicrobial resistance
- The development of an evidence-based street food vending model within a socioecological framework: A guide for African countries
- Sociodemographic changes and trends in the rates of new perinatal HIV diagnoses and transmission in Spain from 1997 to 2015
- Patient navigation services for cancer care in low-and middle-income countries: A scoping review
- Weather extremes and perinatal mortality – Seasonal and ethnic differences in northern Sweden, 1800-1895
- Cognitive, relational and task crafting: Spanish adaptation and analysis of psychometric properties of the Job Crafting Questionnaire
- Maternal and perinatal death surveillance and response in Ethiopia: Achievements, challenges and prospects
- Identification and characterisation of capidermicin, a novel bacteriocin produced by Staphylococcus capitis
- Joint emulation of Earth System Model temperature-precipitation realizations with internal variability and space-time and cross-variable correlation: fldgen v2.0 software description
- Extensive culturomics of 8 healthy samples enhances metagenomics efficiency
- Macroepidemiological aspects of porcine reproductive and respiratory syndrome virus detection by major United States veterinary diagnostic laboratories over time, age group, and specimen
- Correction: Low dose naltrexone: Effects on medication in rheumatoid and seropositive arthritis. A nationwide register-based controlled quasi-experimental before-after study
- Correction: Human indole(ethyl)amine-N-methyltransferase (hINMT) catalyzed methylation of tryptamine, dimethylsulfide and dimethylselenide is enhanced under reducing conditions - A comparison between 254C and 254F, two common hINMT variants
- Myofibrillar function differs markedly between denervated and dexamethasone-treated rat skeletal muscles: Role of mechanical load
- Quantitation of eumelanin and pheomelanin markers in diverse biological samples by HPLC-UV-MS following solid-phase extraction
- Kinetics of mean platelet volume predicts mortality in patients with septic shock
- An integrated epigenome and transcriptome analysis identifies PAX2 as a master regulator of drug resistance in high grade pancreatic ductal adenocarcinoma
- Combining CDK4/6 inhibitors ribociclib and palbociclib with cytotoxic agents does not enhance cytotoxicity
- Association of Medicaid expansion with health insurance coverage by marital status and sex
- Are current approaches for measuring access to clean water and sanitation inclusive of people with disabilities? Comparison of individual- and household-level access between people with and without disabilities in the Tanahun district of Nepal
- A proteomic clock for malignant gliomas: The role of the environment in tumorigenesis at the presymptomatic stage
- Monitoring Universal Health Coverage (UHC) in high Tuberculosis burden countries: Tuberculosis mortality an important tracer of UHC service coverage
- RCT evaluation of Skhokho: A holistic school intervention to prevent gender-based violence among South African Grade 8s
- On the use of Action Units and fuzzy explanatory models for facial expression recognition
- A systematic review of complementary and alternative medicine in oncology: Psychological and physical effects of manipulative and body-based practices
- What factors best explain attitudes to snow leopards in the Nepal Himalayas?
- Determinants of temperature sensitivity of soil respiration with the decline of a foundation species
- Mindfulness meditation, time judgment and time experience: Importance of the time scale considered (seconds or minutes)
- Regional, institutional, and departmental factors associated with gender diversity among BS-level chemical and electrical engineering graduates
- Transepithelial transport of P-glycoprotein substrate by the Malpighian tubules of the desert locust
- Sex affects immunolabeling for histone 3 K27me3 in the trophectoderm of the bovine blastocyst but not labeling for histone 3 K18ac
- A survey of public attitudes toward uterus transplantation, surrogacy, and adoption in Japan
- Replacing plasma membrane outer leaflet lipids with exogenous lipid without damaging membrane integrity
- Accurate dried blood spots collection in the community using non-medically trained personnel could support scaling up routine viral load testing in resource limited settings
- Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study
- Antimicrobial efficacy of commercially available endodontic bioceramic root canal sealers: A systematic review
- The motility-based swim-up technique separates bull sperm based on differences in metabolic rates and tail length
- Synbiotic supplementation to decrease Salmonella colonization in the intestine and carcass contamination in broiler birds
- Bexarotene therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer´s disease
- States with higher minimum wages have lower STI rates among women: Results of an ecological study of 66 US metropolitan areas, 2003-2015
- Weakening the subjective sensation of own hand ownership does not interfere with rapid finger movements
- Identification of DNA methyltransferases and demethylases in Solanum melongena L., and their transcription dynamics during fruit development and after salt and drought stresses
- Environmental conditions for Jamestown Canyon virus correlated with population-level resource selection by white-tailed deer in a suburban landscape
- The contribution of linear perspective cues and texture gradients in the perceptual rescaling of stimuli inside a Ponzo illusion corridor
- Cerebral blood flow imbalance is associated with motor outcome after pediatric arterial ischemic stroke
- Particularly neglected in countries with other challenges: High Toxoplasma gondii seroprevalence in pregnant women in Kabul, Afghanistan, while a low proportion know about the parasite
- Implementing advance care planning in routine nursing home care: The development of the theory-based ACP+ program
- Identifying genetic lineages through shape: An example in a cosmopolitan marine turtle species using geometric morphometrics
- The causality of borrowing: Lexical loans in Eurasian languages
- The uptake of the pharmacy-dispensed naloxone kit program in Ontario: A population-based study
- Gaze and body cues interplay during interactive requests
- Acetylcholine-mediated top-down attention improves the response to bottom-up inputs by deformation of the attractor landscape
- Deep architectures for long-term stock price prediction with a heuristic-based strategy for trading simulations
- Vaccination status of patients using anti-TNF therapy and the physicians’ behavior shaping the phenomenon: Mixed-methods approach
- Organizational justice and illness reporting among Japanese employees with chronic diseases
- CavBench: A benchmark for protein cavity detection methods
- Antimicrobial resistance (AMR) and molecular characterization of Neisseria gonorrhoeae in Ghana, 2012-2015
- Prevalence of methicillin-resistant Staphylococcus aureus in healthy Chinese population: A system review and meta-analysis
- Suppression treatment differentially influences the microbial community and the occurrence of broad host range plasmids in the rhizosphere of the model cover crop Avena sativa L.
- Risk of pneumonia among residents living near goat and poultry farms during 2014-2016
- Lipid levels after childbirth and association with number of children: A population-based cohort study
- Birth outcomes in women who have taken adalimumab in pregnancy: A prospective cohort study
- ECMO with vasopressor use during early endotoxic shock: Can it improve circulatory support and regional microcirculatory blood flow?
- Effects of dietary intake and nutritional status on cerebral oxygenation in patients with chronic kidney disease not undergoing dialysis: A cross-sectional study
- Micro-RNA 150-5p predicts overt heart failure in patients with univentricular hearts
- Flexible learning spaces facilitate interaction, collaboration and behavioural engagement in secondary school
- Clinical significance and prognostic role of hypoxia-induced microRNA 382 in gastric adenocarcinoma
- Genome-wide investigation of superoxide dismutase (SOD) gene family and their regulatory miRNAs reveal the involvement in abiotic stress and hormone response in tea plant (Camellia sinensis)
- Classifying recurrent Mycobacterium tuberculosis cases in Georgia using MIRU-VNTR typing
- Prevalence of Trypanosoma cruzi infection in active military population of The Colombian National Army gathered in five departments
- An observational study comparing HPV prevalence and type distribution between HPV-vaccinated and -unvaccinated girls after introduction of school-based HPV vaccination in Norway
- Sarcopenia as a prognostic factor for survival in patients with locally advanced gastroesophageal adenocarcinoma
- Increased aggression and reduced aversive learning in honey bees exposed to extremely low frequency electromagnetic fields
- Attending to design when developing complex health interventions: A qualitative interview study with intervention developers and associated stakeholders
- Increased fecundity of Aphis fabae on Vicia faba plants following seed or leaf inoculation with the entomopathogenic fungus Beauveria bassiana
- Is summer food intake a limiting factor for boreal browsers? Diet, temperature, and reproduction as drivers of consumption in female moose
- Characterization of sound scattering layers in the Bay of Biscay using broadband acoustics, nets and video
- Conducting human challenge studies in LMICs: A survey of researchers and ethics committee members in Thailand
- eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization
- Clinical use of SAND battery to evaluate language in patients with Progressive Supranuclear Palsy
- The interplay of personality and attitudes toward own aging across two decades of later life
- Robust automated reading of the skin prick test via 3D imaging and parametric surface fitting
- Reconstructing the population history of the sandy beach amphipod Haustorioides japonicus using the calibration of demographic transition (CDT) approach
- A psychoacoustic application for the adjustment of electrical hearing thresholds in cochlear implant patients
- Correction: Blue light-dependent human magnetoreception in geomagnetic food orientation
- Re-evaluation of a Tn5::gacA mutant of Pseudomonas syringae pv. tomato DC3000 uncovers roles for uvrC and anmK in promoting virulence
- Sugar-sweetened beverages and colorectal cancer risk in the California Teachers Study
- Illuminating biological pathways for drug targeting in head and neck squamous cell carcinoma
- The impact of shared knowledge on speakers’ prosody
- Effects of insecticides, fipronil and imidacloprid, on the growth, survival, and behavior of brown shrimp Farfantepenaeus aztecus
- Prevalence of pectus excavatum (PE), pectus carinatum (PC), tracheal hypoplasia, thoracic spine deformities and lateral heart displacement in thoracic radiographs of screw-tailed brachycephalic dogs
- Validation of the vignette-based German Exercise Causality Orientation Scale (G-ECOS)
- Hierarchical classification of snowmelt episodes in the Pyrenees using seismic data
- A national survey of videolaryngoscopes and alternative intubation devices in Hungary
- The relevance of U.S. Strategic Highway Safety Plans in a future context
- Inhaled nebulized glatiramer acetate against Gram-negative bacteria is not associated with adverse pulmonary reactions in healthy, young adult female pigs
- Anti-inflammatory effects induced by ultralow concentrations of bupivacaine in combination with ultralow concentrations of sildenafil (Viagra) and vitamin D3 on inflammatory reactive brain astrocytes
- Access to unauthorized hepatitis C generics: Perception and knowledge of physicians, pharmacists, patients and non-healthcare professionals
- Urban commuting dynamics in response to public transit upgrades: A big data approach
- Intestinal mucosal injury induced by obstructive jaundice is associated with activation of TLR4/TRAF6/NF-κB pathways
- When resolution does matter: Modelling indirect contacts in dairy farms at different levels of detail
- Molecular epidemiology of Mycoplasma hyorhinis porcine field isolates in the United States
- Liquorice ingestion attenuates vasodilatation via exogenous nitric oxide donor but not via β2-adrenoceptor stimulation
- Adolescents living with HIV are at higher risk of death and loss to follow up from care: Analysis of cohort data from eight health facilities in Ethiopia
- Identification of social relation within pedestrian dyads
- Blood donation and health status based on SF-36: The mediating effect of cognition in blood donation
- The cost-effectiveness of controlling cervical cancer using a new 9-valent human papillomavirus vaccine among school-aged girls in Australia
- Inactivation of chronic wasting disease prions using sodium hypochlorite
- Analysing linear multivariate pattern transformations in neuroimaging data
- Ecological aesthetic assessment of a rebuilt wetland restored from farmland and management implications for National Wetland Parks
- A method for predicting background advertisement exposure parameters in sporting events: Televised football game approach
- Self-reported and experimentally induced self-disgust is heightened in Parkinson’s disease: Contribution of behavioural symptoms
- Associations between nocturnal sleep duration, midday nap duration and body composition among adults in Southwest China
- Short-term effects of video gaming on brain response during working memory performance
- Molecular detection and genetic characterization of Bartonella species from rodents and their associated ectoparasites from northern Tanzania
- Estimation of the number of HCV-positive patients in Italy
- Comparative cost analysis of point-of-care versus laboratory-based testing to initiate and monitor HIV treatment in South Africa
- Insights into the behavior of six rationally designed peptides based on Escherichia coli’s OmpA at the water-dodecane interface
- Identification of muscle-specific candidate genes in Simmental beef cattle using imputed next generation sequencing
- A game theoretic setting of capitation versus fee-for-service payment systems
- In utero exposure to economic fluctuations and birth outcomes: An analysis of the relevance of the local unemployment rate in Brazilian state capitals
- QTL mapping for aluminum tolerance in RIL population of soybean (Glycine max L.) by RAD sequencing
- Establishing an infrastructure for collaboration in primate cognition research
- Evaluation of left ventricular dimension and systolic function by standard transthoracic echocardiography before and 24-hours after percutaneous closure of patent ductus arteriosus in 120 dogs
- Modeling environmental variability and network formation among pastoral nomadic households: Implications for the rise of the Mongol Empire
- Changes in real-life practice for hepatocellular carcinoma patients in the Republic of Korea over a 12-year period: A nationwide random sample study
- Correction: Homology analysis of malware based on ensemble learning and multifeatures
- Illness beliefs and emotional responses in mildly disabled stroke survivors: A qualitative study
- Extended-wavelength diffuse reflectance spectroscopy with a machine-learning method for in vivo tissue classification
- Modeling the natural history of fatty liver using lifestyle–related risk factors: Effects of body mass index (BMI) on the life–course of fatty liver
- Development of a recombinant replication-deficient rabies virus-based bivalent-vaccine against MERS-CoV and rabies virus and its humoral immunogenicity in mice
- Educational achievement at age 9.5 years of children born to mothers maintained on methadone during pregnancy
- Comparative transcriptome analysis of galls from four different host plants suggests the molecular mechanism of gall development
- Experiences with peer support for breastfeeding in Beirut, Lebanon: A qualitative study
- Elucidating optical field directed hierarchical self-assembly of homogenous versus heterogeneous nanoclusters with femtosecond optical tweezers
- Structure establishment of three-dimensional (3D) cell culture printing model for bladder cancer
- Elevated serum alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality
- Correction: Functional atlases for analysis of motor and neuropsychological outcomes after medial globus pallidus and subthalamic stimulation
- Correction: Estimating Body Composition in Adolescent Sprint Athletes: Comparison of Different Methods in a 3 Years Longitudinal Design
- Quality of labor and birth care in Sindh Province, Pakistan: Findings from direct observations at health facilities
- A comparison of sLASER and MEGA-sLASER using simultaneous interleaved acquisition for measuring GABA in the human brain at 7T
- Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis
- Intrabladder pressure as predictor of intra-abdominal pressure in horses
- Pollock avoided hydrodynamic instabilities to paint with his dripping technique
- Metabolomic analysis of the occurrence of bitter fruits on grafted oriental melon plants
- Photo-degradation dynamics of five neonicotinoids: Bamboo vinegar as a synergistic agent for improved functional duration
- Use of acoustic emission to identify novel candidate biomarkers for knee osteoarthritis (OA)
- Cetacean biodiversity, spatial and temporal trends based on stranding records (1920-2016), Victoria, Australia
- Neutrophil elastase inhibitor purification strategy from cowpea seeds
- Correction: Hafting of Middle Paleolithic tools in Latium (central Italy): New data from Fossellone and Sant’Agostino caves
- Coherent poly propagation materials with 3-dimensional photonic control over visible light
- Characterization of Worldwide Olive Germplasm Banks of Marrakech (Morocco) and Córdoba (Spain): Towards management and use of olive germplasm in breeding programs
- Can non-pharmacological interventions reduce hospital admissions in people with dementia? A systematic review
- Metarhizium robertsii ammonium permeases (MepC and Mep2) contribute to rhizoplane colonization and modulates the transfer of insect derived nitrogen to plants
- Genotyping and antimicrobial resistance of Streptococcus uberis isolated from bovine clinical mastitis
- Isotopic compositions of ground ice in near-surface permafrost in relation to vegetation and microtopography at the Taiga–Tundra boundary in the Indigirka River lowlands, northeastern Siberia
- Financial inclusion and intimate partner violence: What does the evidence suggest?
- Are intestinal helminths playing a positive role in tuberculosis risk? A systematic review and meta-analysis
- Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transition
- Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer
- Take one step backward to move forward: Assessment of genetic diversity and population structure of captive Asian woolly-necked storks (Ciconia episcopus)
- Money doesn’t matter! Householders’ intentions to reduce standby power are unaffected by personalised pecuniary feedback
- Validating a scale to measure engineers’ perceived self-efficacy for engineering education outreach
- Effect of d-cycloserine on fear extinction training in adults with social anxiety disorder
- Nursing students and nurses’ knowledge and attitudes regarding children’s pain: A comparative cross-sectional study
- Inter-method and anatomical correlates of episodic memory tests in the Alzheimer’s Disease spectrum
- Knowledge, attitudes and medical practice regarding hepatitis B prevention and management among healthcare workers in Northern Vietnam
- Development and validation of a symptom assessment tool for postmicturition dribble: A prospective, multicenter, observational study in Korea
- Identification of closely related Ixodes species by protein profiling with MALDI-TOF mass spectrometry
- When calculators lie: A demonstration of uncritical calculator usage among college students and factors that improve performance
- Socio-economic characteristics and career intentions of the WiSDOM health professional cohort in South Africa
- Correction: Neural computational model GrowthEstimate: A model for studying living resources through digestive efficiency
- Social proximity in dairy calves is affected by differences in pessimism
- Amphibian skin-associated Pigmentiphaga: Genome sequence and occurrence across geography and hosts
- Expanded consumer niche widths may signal an early response to spatial protection
- Moral grandstanding in public discourse: Status-seeking motives as a potential explanatory mechanism in predicting conflict
- Adipose stem cells in reparative goat mastitis mammary gland
- Seventy-five mosses and liverworts found frozen with the late Neolithic Tyrolean Iceman: Origins, taphonomy and the Iceman’s last journey
- Hyaluronic acid and epidermal growth factor improved the bovine embryo quality by regulating the DNA methylation and expression patterns of the focal adhesion pathway
- Associations among knowledge, attitudes, and practices toward palliative care consultation service in healthcare staffs: A cross-sectional study
- A novel, wearable, electronic visual aid to assist those with reduced peripheral vision
- Genetic diversity and population structure of the Mediterranean sesame core collection with use of genome-wide SNPs developed by double digest RAD-Seq
- Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression
- Mobile health-based physical activity intervention for individuals with spinal cord injury in the community: A pilot study
- Factors influencing cultivated ginseng (Panax ginseng C. A. Meyer) bioactive compounds
- Estimation of soil pH with geochemical indices in forest soils
- Multiplexed editing of a begomovirus genome restricts escape mutant formation and disease development
- Correlates of longitudinal leukocyte telomere length in the Costa Rican Longevity Study of Healthy Aging (CRELES): On the importance of DNA collection and storage procedures
- Collaboration and followership: A stochastic model for activities in social networks
- Evaluating access to oral anti-diabetic medicines: A cross-sectional survey of prices, availability and affordability in Shaanxi Province, Western China
- Comparison of corneal elevation and pachymetry measurements made by two state of the art corneal tomographers with different measurement principles
- Use of a pressure-sensing walkway system for biometric assessment of gait characteristics in goats
- Current status and direct medical cost of amyotrophic lateral sclerosis in the region of Catalonia: A population-based analysis
- Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion
- Can work climate foster pro-environmental behavior inside and outside of the workplace?
- Gene editing of PKLR gene in human hematopoietic progenitors through 5’ and 3’ UTR modified TALEN mRNA
- Pelvic alignment changes during the perinatal period
- Interatrial blocks prevalence and risk factors for human immunodeficiency virus-infected persons
- Life-course trajectories of body mass index and subsequent cardiovascular risk among Chinese population
- Inhibitory interaction networks among coevolved Streptomyces populations from prairie soils
- Exploiting contextual information to improve call prediction
- Visual inputs decrease brain activity in frontal areas during silent lipreading
- The synergistic effects of TaAGP.L-B1 and TaSSIVb-D mutations in wheat lead to alterations of gene expression patterns and starch content in grain development
- Live-attenuated H1N1 influenza vaccine candidate displays potent efficacy in mice and ferrets
- Robust, real-time generic detector based on a multi-feature probabilistic method
- Maize leaves drought-responsive genes revealed by comparative transcriptome of two cultivars during the filling stage
- Xenon lamps used for fruit surface sterilization can increase the content of total flavonols in leaves of Lactuca sativa L. without any negative effect on net photosynthesis
- An alternative procedure to obtain the mortality rate with non-linear functions: Application to the case of the Spanish population
- Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis
- Longitudinal assessment of post-surgical physical activity in endometrial and ovarian cancer patients
- THINGS: A database of 1,854 object concepts and more than 26,000 naturalistic object images
- Evaluation of ranibizumab and aflibercept for the treatment of diabetic macular edema in daily clinical practice
- Proteomic analysis of Escherichia coli detergent-resistant membranes (DRM)
- Correction: Effect of curcuminoids and curcumin derivate products on thioredoxin-glutathione reductase from Taenia crassiceps cysticerci. Evidence suggesting a curcumin oxidation product as a suitable inhibitor
- Correction: Predicting childhood obesity using electronic health records and publicly available data
- Correction: Estimating the value of tropical coastal wetland habitats to fisheries: Caveats and assumptions
- Correction: The effects of sympathetic activity induced by ice water on blood flow and brachial artery flow-mediated dilatation response in healthy volunteers
- Determinants of frailty development and progression using a multidimensional frailty index: Evidence from the English Longitudinal Study of Ageing
- Supporting informed clinical trial decisions: Results from a randomized controlled trial evaluating a digital decision support tool for those with intellectual disability
- BMAL1 associates with chromosome ends to control rhythms in TERRA and telomeric heterochromatin
- Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry
- Hepatopulmonary syndrome has low prevalence of pulmonary vascular abnormalities on chest computed tomography
- Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study
- Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15
- The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population
- Expression of Concern: The Coordination of Cell Growth during Fission Yeast Mating Requires Ras1-GTP Hydrolysis
- Correction: Lentivirus-Mediated Knockdown of Astrocyte Elevated Gene-1 Inhibits Growth and Induces Apoptosis through MAPK Pathways in Human Retinoblastoma Cells
- Relationship between self-disclosure to first acquaintances and subjective well-being in people with schizophrenia spectrum disorders living in the community
- Remarkable cell recovery from cerebral ischemia in rats using an adaptive escalator-based rehabilitation mechanism
- Integrating environmental and neighborhood factors in MaxEnt modeling to predict species distributions: A case study of Aedes albopictus in southeastern Pennsylvania
- Post-overdose interventions triggered by calling 911: Centering the perspectives of people who use drugs (PWUDs)
- The prevalence of intimate partner violence among couples signing up for universally offered parent preparation
- Analysis of gear surface morphology based on gray level co-occurrence matrix and fractal dimension
- Abiotic, present-day and historical effects on species, functional and phylogenetic diversity in dry grasslands of different age
- Clonality analysis of pulmonary tumors by genome-wide copy number profiling
- A relictual troglomorphic harvestman discovered in a volcanic cave of western Argentina: Otilioleptes marcelae, new genus, new species, and Otilioleptidae, new family (Arachnida, Opiliones, Gonyleptoidea)
- HIV drug resistance in persons who inject drugs enrolled in an HIV prevention trial in Indonesia, Ukraine, and Vietnam: HPTN 074
- Dietary acid load significantly predicts 10-years survival in patients underwent coronary artery bypass grafting (CABG) surgery
- Regulation of nitrogen availability results in changes in grain protein content and grain storage subproteomes in barley (Hordeum vulgare L.)
- Diagnostic test evaluation methodology: A systematic review of methods employed to evaluate diagnostic tests in the absence of gold standard – An update
- Longitudinal trends of and factors associated with inappropriate antibiotic prescribing for non-bacterial acute respiratory tract infection in Japan: A retrospective claims database study, 2012–2017
- Revealing users’ experience and social interaction outcomes following a web-based smoking prevention intervention for adolescents: A qualitative study
- Coordination of human movements resulting in motor strategies exploited by skilled players during a throwing task
- Impact of pericardiectomy on exercise capacity and sleep of patients with chronic constrictive pericarditis
- Blue-violet light decreases VEGFa production in an in vitro model of AMD
- Identification of protein changes in the blood plasma of lung cancer patients subjected to chemotherapy using a 2D-DIGE approach
- Speed of processing training and depression in assisted and independent living: A randomized controlled trial
- Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient
- What happens in the brain of meditators when perception changes but not the stimulus?
- Comparison of HIV-1 Vif and Vpu accessory proteins for delivery of polyepitope constructs harboring Nef, Gp160 and P24 using various cell penetrating peptides
- Are degree of urbanisation and travel times to healthcare services associated with the processes of care and outcomes of heart failure? A retrospective cohort study based on administrative data
- A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing
- Influence of transcutaneous vagus nerve stimulation on cardiac vagal activity: Not different from sham stimulation and no effect of stimulation intensity
- Co-prescription network reveals social dynamics of opioid doctor shopping
- Contractile properties of superficial skeletal muscle affect postural control in healthy young adults: A test of the rambling and trembling hypothesis
- Does intrauterine crowding affect the force generating capacity and muscle composition of the piglet front limb?
- Correction: Measuring compassionate healthcare with the 12-item Schwartz Center Compassionate Care Scale
- Facilitators and barriers to traditional medicine use among cancer patients in Malawi
- Expression of CMV protein pp65 in cutaneous malignant melanoma
- The evolution of mental health outcomes across a combat deployment cycle: A longitudinal study of a Guam-based National Guard unit
- Caesarean section delivery and childhood obesity in a British longitudinal cohort study
- Incidence, characteristics, and mortality of infective endocarditis in France in 2011
- Pfcyp51 exclusively determines reduced sensitivity to 14α-demethylase inhibitor fungicides in the banana black Sigatoka pathogen Pseudocercospora fijiensis
- Evaluation of the bacterial ocular surface microbiome in clinically normal cats before and after treatment with topical erythromycin
- Histological and developmental insights into the herbivorous dentition of tapinocephalid therapsids
- Differential immunomodulation of T-cells by immunoglobulin replacement therapy in primary and secondary antibody deficiency
- A longitudinal study on perceived health in cardiovascular patients: The role of conscientiousness, subjective wellbeing and cardiac self-efficacy
- The effectiveness of interferon beta versus glatiramer acetate and natalizumab versus fingolimod in a Polish real-world population
- Interactions of Streptococcus suis serotype 9 with host cells and role of the capsular polysaccharide: Comparison with serotypes 2 and 14
- Honey bee and native solitary bee foraging behavior in a crop with dimorphic parental lines
- A flexible formula for incorporating distributive concerns into cost-effectiveness analyses: Priority weights
- Correction: Lack of association between hypothyroxinemia of prematurity and transient thyroid abnormalities with adverse long term neurodevelopmental outcome in very low birth weight infants
- A reconnaissance survey of farmers’ awareness of hypomagnesaemic tetany in UK cattle and sheep farms
- Health workers’ perception of malaria rapid diagnostic test and factors influencing compliance with test results in Ebonyi state, Nigeria
- Conformational flexibility of fork-remodeling helicase Rad5 shown by full-ensemble hybrid methods
- The increasing importance of fellowships and career development awards in the careers of early-stage biomedical academic researchers
- Occurrence and stability of hetero-hexamer associations formed by β-carboxysome CcmK shell components
- Auxin driven indoleamine biosynthesis and the role of tryptophan as an inductive signal in Hypericum perforatum (L.)
- Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development
- Distance to large rivers affects fish diversity patterns in highly dynamic streams of Central Amazonia
- Real vs. immersive-virtual emotional experience: Analysis of psycho-physiological patterns in a free exploration of an art museum
- Modulation of brain tumor risk by genetic SNPs in PARP1gene: Hospital based case control study
- Processed meat intake and chronic disease morbidity and mortality: An overview of systematic reviews and meta-analyses
- Modeling ENSO impact on rice production in the Mekong River Delta
- The feasibility of a behavioral group intervention after weight-loss surgery: A randomized pilot trial
- EMR-integrated minimal core dataset for routine health care and multiple research settings: A case study for neuroinflammatory demyelinating diseases
- A review of a 13-month period of FilmArray Meningitis/Encephalitis panel implementation as a first-line diagnosis tool at a university hospital
- Increased BMI has a linear association with late-onset preeclampsia: A population-based study
- Autoantibody production significantly decreased with APRIL/BLyS blockade in murine chronic rejection kidney transplant model
- Vancomycin-resistance gene cluster, vanC, in the gut microbiome of acute leukemia patients undergoing intensive chemotherapy
- Telomere length in COPD: Relationships with physical activity, exercise capacity, and acute exacerbations
- Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP
- Impact of faecal calprotectin measurement on clinical decision-making in patients with Crohn’s disease and ulcerative colitis
- Additive effects of a small molecular PCNA inhibitor PCNA-I1S and DNA damaging agents on growth inhibition and DNA damage in prostate and lung cancer cells
- Autophagy is important to the acidogenic metabolism of Aspergillus niger
- Continuous ratings of movie watching reveal idiosyncratic dynamics of aesthetic enjoyment
- Sensitivity and specificity of serum soluble interleukin-2 receptor for diagnosing sarcoidosis in a population of patients suspected of sarcoidosis
- Enhancing genomic selection by fitting large-effect SNPs as fixed effects and a genotype-by-environment effect using a maize BC1F3:4 population
- Quantitation and modeling of post-translational modifications in a therapeutic monoclonal antibody from single- and multiple-dose monkey pharmacokinetic studies using mass spectrometry
- Microbial induced solidification and stabilization of municipal solid waste incineration fly ash with high alkalinity and heavy metal toxicity
- Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses
- A fault-tolerant aware scheduling method for fog-cloud environments
- Correction: BCG vaccination and tuberculosis prevention: A forty years cohort study, Monastir, Tunisia
- Correction: Perceptions among transgender women of factors associated with the access to HIV/AIDS-related health services in Yogyakarta, Indonesia
- Assessing the convergent validity between the automated emotion recognition software Noldus FaceReader 7 and Facial Action Coding System Scoring
- Deep learning based banana plant detection and counting using high-resolution red-green-blue (RGB) images collected from unmanned aerial vehicle (UAV)
- Comparison of cardiorespiratory fitness between preschool children with normal and excess body adipose ~ An observational study
- Intraregional differences in renal function in the Northern Netherlands: The Lifelines Cohort Study
- Effects of MCHM on yeast metabolism
- Signaling impacts of GMO labeling on fruit and vegetable demand
- Dietary specialization depending on ecological context and sexual differences in Asiatic black bears
- Electronic device use and beverage related sugar and caffeine intake in US adolescents
- Isolation and characterization of five novel probiotic strains from Korean infant and children faeces
- Correction: Silymarin in non-cirrhotics with non-alcoholic steatohepatitis: A randomized, double-blind, placebo controlled trial
- Correction: Anatomical analysis of antebrachial cutaneous nerve distribution pattern and its clinical implications for sensory reconstruction
- Endothelial nitric oxide synthase limits host immunity to control disseminated Candida albicans infections in mice
- Lack of detection of Candida nivariensis and Candida bracarensis among 440 clinical Candida glabrata sensu lato isolates in Kuwait
- Nonlinear dynamics captures brain states at different levels of consciousness in patients anesthetized with propofol
- Visual encounters on line transect surveys under-detect carnivore species: Implications for assessing distribution and conservation status
- Menstrual health communication among Indian adolescents: A mixed-methods study
- Fast fluorescence in situ hybridisation for the enhanced detection of MET in non-small cell lung cancer
- The influence of personality on the effect of iTBS after being stressed on cortisol secretion
- Parental and peer support and modelling in relation to domain-specific physical activity participation in boys and girls from Germany
- Oral delivery of water-soluble compounds to the phytoseiid mite Neoseiulus californicus (Acari: Phytoseiidae)
- Force perceptual bias caused by muscle activity in unimanual steering
- Correction: Comparison of risk models for mortality and cardiovascular events between machine learning and conventional logistic regression analysis
- Correction: Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium
- Providencia entomophila sp. nov., a new bacterial species associated with major olive pests in Tunisia
- Safety of intravitreal ziv-aflibercept in choroido-retinal vascular diseases: A randomised double-blind intervention study
- A novel framework for evaluating the impact of individual decision-making on public health outcomes and its potential application to study antiviral treatment collection during an influenza pandemic
- Reduction of the rocuronium-induced withdrawal reflex by MR13A10A, a generic rocuronium with a novel solution: A randomized, controlled study
- Emotionally expressed voices are retained in memory following a single exposure
- Megabenthic communities of the Ligurian deep continental shelf and shelf break (NW Mediterranean Sea)
- Election forensics: Using machine learning and synthetic data for possible election anomaly detection
- A randomized crossover trial comparing the Nifty cup to a medicine cup in preterm infants who have difficulty breastfeeding at Komfo Anokye Teaching Hospital (KATH) in Kumasi, Ghana
- The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease
- Genomic impact of severe population decline in a nomadic songbird
- Evolution of high-sensitivity troponin-T and echocardiography parameters in patients undergoing high efficiency on-line hemodiafiltration versus conventional low-flux hemodialysis
- Full genome characterization of 12 citrus tatter leaf virus isolates for the development of a detection assay
- Intake of myo-inositol hexaphosphate and urinary excretion of inositol phosphates in Wistar rats: Gavage vs. oral administration with sugar
- Enhancing financial security of female sex workers through a community-led intervention in India: Evidence from a longitudinal survey
- In-silico prediction of novel genes responsive to drought and salinity stress tolerance in bread wheat (Triticum aestivum)
- Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
- Partitioning the risk of tuberculosis transmission in household contact studies
- Recommendation system in social networks with topical attention and probabilistic matrix factorization
- Using satellite-measured relative humidity for prediction of Metisa plana’s population in oil palm plantations: A comparative assessment of regression and artificial neural network models
- A drug interaction study investigating the effect of Rifabutin on the pharmacokinetics of Maraviroc in healthy subjects
- Emotional and behavioral problems, social competence and risk factors in 6–16-year-old students in Beijing, China
- Clinicopathologic and prognostic significance of tumor-associated macrophages in patients with hepatocellular carcinoma: A meta-analysis
- Involution of retinopathy of prematurity and neurodevelopmental outcomes after intravitreal bevacizumab treatment
- Travel demand and distance analysis for free-floating car sharing based on deep learning method
- Genome-wide identification, characterization, expression and enzyme activity analysis of coniferyl alcohol acetyltransferase genes involved in eugenol biosynthesis in Prunus mume
- Population analysis of D6-like plasmid prophage variants associated with specific IncC plasmid types in the emerging Salmonella Typhimurium ST213 genotype
- The high resource impact of reformatting requirements for scientific papers
- Egg yolk-free cryopreservation of bull semen
- Fine epitope mapping of glycoprotein Gn in Guertu virus
- Are hospital nurse staffing practices associated with postoperative cardiac events and death? A systematic review
- Dysregulation of macrophage development and phenotype in diabetic human macrophages can be rescued by Hoxa3 protein transduction
- Aging and the wandering brain: Age-related differences in the neural correlates of stimulus-independent thoughts
- Elucidating stygofaunal trophic web interactions via isotopic ecology
- Experimental characterization of two archaeal inosine 5'-monophosphate cyclohydrolases
- Scientist and data architect collaborate to curate and archive an inner ear electrophysiology data collection
- No effect of triple-pulse TMS medial to intraparietal sulcus on online correction for target perturbations during goal-directed hand and foot reaches
- Correction: Controlling Social Stress in Virtual Reality Environments
- TNF-α is responsible for the contribution of stromal cells to osteoclast and odontoclast formation during orthodontic tooth movement
- Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children
- Alteration of humoral, cellular and cytokine immune response to inactivated influenza vaccine in patients with Sickle Cell Disease
- To tweet or not to tweet, that is the question: A randomized trial of Twitter effects in medical education
- Visualizing a field of research: A methodology of systematic scientometric reviews
- True Colors: Commercially-acquired morphological genotypes reveal hidden allele variation among dog breeds, informing both trait ancestry and breed potential
- Impact of the detection of ζ-globin chains and hemoglobin Bart’s using immunochromatographic strip tests for α0-thalassemia (--SEA) differential diagnosis
- Cognitive impairment and medication adherence post-stroke: A five-year follow-up of the ASPIRE-S cohort
- Correction: Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism
- Correction: Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana
- Correction: Precision public health: Mapping socioeconomic disparities in opioid dispensations at Swedish pharmacies by Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA)
- Epidemiological, clinical and laboratory characteristics of the measles resurgence in the Republic of Serbia in 2014-2015
- Macro-charcoal accumulation in floodplain wetlands: Problems and prospects for reconstruction of fire regimes and environmental conditions
- Stage at diagnosis and stage-specific survival of breast cancer in Latin America and the Caribbean: A systematic review and meta-analysis
- Correction: Retraction: Stiffening-Induced High Pulsatility Flow Activates Endothelial Inflammation via a TLR2/NF-κB Pathway
- TEM8/ANTXR1-specific CAR T cells mediate toxicity in vivo
- Clinical impact of intraoperative hyperlactatemia during craniotomy
- Intubation with channeled versus non-channeled video laryngoscopes in simulated difficult airway by junior doctors in an out-of-hospital setting: A crossover manikin study
- Age and growth of stocked juvenile Shoal Bass in a tailwater: Environmental variation and accuracy of daily age estimates
- Sex-specific differences in risk factors of lymph node metastasis in patients with early gastric cancer
- The impact of electroconvulsive therapy on the spatial QRS-T angle and cardiac troponin T concentration in psychiatric patients
- BDNF, NT-3 and Trk receptor agonist monoclonal antibodies promote neuron survival, neurite extension, and synapse restoration in rat cochlea ex vivo models relevant for hidden hearing loss
- Investigation on the hereditary basis of colorectal cancers in an African population with frequent early onset cases
- Comparison of cancer prevalence between patients with glomerulonephritis and the general population at the time of kidney biopsy
- Predictors of time to unfavorable treatment outcomes among patients with multidrug resistant tuberculosis in Oromia region, Ethiopia
- Experimentally validated simulation of coronary stents considering different dogboning ratios and asymmetric stent positioning
- The membrane effects of melittin on gastric and colorectal cancer
- Exclusive breastfeeding policy, practice and influences in South Africa, 1980 to 2018: A mixed-methods systematic review
- Hippocampal subfield volumes and pre-clinical Alzheimer’s disease in 408 cognitively normal adults born in 1946
- Uncorrected low hyperopia in young subjects induces postural instability even in those with clear visual acuity
- Membrane associated proteins of two Trichomonas gallinae clones vary with the virulence
- Awareness, current use of electronic cigarettes and associated smoking factors in Zhejiang Chinese adolescents
- Associations between pre-pregnancy BMI, gestational weight gain, and prenatal diet quality in a national sample
- Effects of continuous ketamine infusion on hemodynamics and mortality in critically ill children
- Optofluidic laser speckle image decorrelation analysis for the assessment of red blood cell storage
- Complete chloroplast genome sequence and phylogenetic analysis of Spathiphyllum 'Parrish'
- Strategic science communication as planned behavior: Understanding scientists’ willingness to choose specific tactics
- Understanding spatial patterns of soils for sustainable agriculture in northern Ethiopia’s tropical mountains
- Does Japan’s national nutrient-based dietary guideline improve lifestyle-related disease outcomes? A retrospective observational cross-sectional study
- Agitation near the end of life with dementia: An ethnographic study of care
- Tick-borne encephalitis virus infections in Germany. Seasonality and in-year patterns. A retrospective analysis from 2001-2018
- Encouraging perspective taking: Using narrative writing to induce empathy for others engaging in negative health behaviors
- Considerations of target surface area and the risk of radiosurgical toxicity
- Correction: A comparative study of RNA-Seq and microarray data analysis on the two examples of rectal-cancer patients and Burkitt Lymphoma cells
- Effect of using immobilization device in fluoroscopic study in pediatric patient: Focused on radiation dose reduction in voiding cystourethrogram
- Temporal trends in breast cancer survival by race and ethnicity: A population-based cohort study
- Contamination of hospital surfaces with respiratory pathogens in Bangladesh
- The impact on the bioenergetic status and oxidative-mediated tissue injury of a combined protocol of hypothermic and normothermic machine perfusion using an acellular haemoglobin-based oxygen carrier: The cold-to-warm machine perfusion of the liver
- Association between hospital interval and survival in patients with oral cancer: A waiting time paradox
- Translating a stress management intervention for rural Latina breast cancer survivors: The Nuevo Amanecer-II
- Comprehensive management of obstructive sleep apnea by telemedicine: Clinical improvement and cost-effectiveness of a Virtual Sleep Unit. A randomized controlled trial
- Proteomic characterisation of the Chlamydia abortus outer membrane complex (COMC) using combined rapid monolithic column liquid chromatography and fast MS/MS scanning
- Harnessing therapeutic viruses as a delivery vehicle for RNA-based therapy
- Korean soybean core collection: Genotypic and phenotypic diversity population structure and genome-wide association study
- Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study
- Measurement of structural integrity of the spinal cord in patients with amyotrophic lateral sclerosis using diffusion tensor magnetic resonance imaging
- Typological analysis of public-private partnerships in the veterinary domain
- Improved clinical outcome after medial open-wedge osteotomy despite cartilage lesions in the lateral compartment
- Rapid and structure-specific cellular uptake of selected steroids
- Avoiding gambling harm: An evidence-based set of safe gambling practices for consumers
- Epidemiology of chronic pain in Ukraine: Findings from the World Mental Health Survey
- PIAS1 is not suitable as a urothelial carcinoma biomarker protein and pharmacological target
- Double triage to identify poorly annotated genes in maize: The missing link in community curation
- N-acetyl cysteine restores the fertility of vitrified–warmed mouse oocytes derived through ultrasuperovulation
- Architecture of population-differentiated polymorphisms in the human genome
- Linguistic neutrosophic power Muirhead mean operators for safety evaluation of mines
- Extracellular vesicles nanoarray technology: Immobilization of individual extracellular vesicles on nanopatterned polyethylene glycol-lipid conjugate brushes
- Exercise intensity-dependent effects of arm and leg-cycling on cognitive performance
- How information about perpetrators’ nature and nurture influences assessments of their character, mental states, and deserved punishment
- Stringent response governs the oxidative stress resistance and virulence of Francisella tularensis
- In silico assessment of human Calprotectin subunits (S100A8/A9) in presence of sodium and calcium ions using Molecular Dynamics simulation approach
- Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment by bioluminescence imaging
- Measurable residual disease monitoring for patients with acute myeloid leukemia following hematopoietic cell transplantation using error corrected hybrid capture next generation sequencing
- Characteristics of complementary medicine therapists in Switzerland: A cross-sectional study
- Lack of generalization between explicit and implicit visuomotor learning
- Diet modulates cecum bacterial diversity and physiological phenotypes across the BXD mouse genetic reference population
- Effects of temperature and salinity on respiratory losses and the ratio of photosynthesis to respiration in representative Antarctic phytoplankton species
- Self-reported non-receipt of HIV test results: A silent barrier to HIV epidemic control in Mozambique
- Plasma midkine concentrations in healthy children, children with increased and decreased adiposity, and children with short stature
- Echocardiography overestimates LV mass in the elderly as compared to cardiac CT
- Efficacy of cotrimoxazole (Sulfamethoxazole-Trimethoprim) as a salvage therapy for the treatment of bone and joint infections (BJIs)
- Molecular mechanism of antimicrobial activity of chlorhexidine against carbapenem-resistant Acinetobacter baumannii
- First identification of the benzimidazole resistance-associated F200Y SNP in the beta-tubulin gene in Ascaris lumbricoides
- Green synthesis of silver nanoparticles using Solanum mammosum L. (Solanaceae) fruit extract and their larvicidal activity against Aedes aegypti L. (Diptera: Culicidae)
- Enterovirus 71 seroepidemiology in Taiwan in 2017 and comparison of those rates in 1997, 1999 and 2007
- Effect of statin on life prognosis in Japanese patients undergoing hemodialysis
- 13C and 15N NMR identification of product compound classes from aqueous and solid phase photodegradation of 2,4,6-trinitrotoluene
- Off-target effects of CRISPRa on interleukin-6 expression
- Exploring the antimicrobial properties of dark-operating ceramic-based nanocomposite materials for the disinfection of indoor air
- Experienced males recognise and avoid mating with non-virgin females in the western flower thrips
- Liver transplantation in patients with a history of migration—A German single center comparative analysis
- Retraction: The Different Role of Notch1 and Notch2 in Astrocytic Gliomas
- Correction: Understanding climate change from a global analysis of city analogues
- Comparison of 4D Flow MRI to 2D Flow MRI in the pulmonary arteries in healthy volunteers and patients with pulmonary hypertension
- The relationship between sleep quality, inappropriate medication use and frailty among older adults in aged care homes in Malaysia
- Clonal diversity and spatial genetic structure in the long-lived herb, Prairie trillium
- Medication histories documentation at the community pharmacy setting: A study from Jordan
- Population dynamics of an invasive bird parasite, Philornis downsi (Diptera: Muscidae), in the Galapagos Islands
- Because you had a bad day: General and daily relations between reactive temperament, emotion regulation, and depressive symptoms in youth
- Socioeconomic status and alcohol use disorders across the lifespan: A co-relative control study
- Generation of deletions and precise point mutations in Dictyostelium discoideum using the CRISPR nickase
- Polymorphisms in vasoactive eicosanoid genes of kidney donors affect biopsy scores and clinical outcomes in renal transplantation
- Adjuvant therapeutic potential of tonabersat in the standard treatment of glioblastoma: A preclinical F98 glioblastoma rat model study
- Validation and perception of a key feature problem examination in neurology
- Gender affirmative HIV care framework: Decisions on feminizing hormone therapy (FHT) and antiretroviral therapy (ART) among transgender women
- Quantifying international human mobility patterns using Facebook Network data
- Localization and characterization of thyroid microcalcifications: A histopathological study
- Young children are the main victims of fast food induced obesity in Brazil
- Understanding self-reported importance of religion/spirituality in a North American sample of individuals at risk for familial depression: A principal component analysis
- Standing balance of professional ballet dancers and non-dancers under different conditions
- 30-day unplanned readmission rate in otolaryngology patients: A population-based study in Thuringia, Germany
- Physical exercise stimulates salivary secretion of cystatins
- Vintage electronics for trusted radiation measurements and verified dismantlement of nuclear weapons
- Keepin’ it real: Linguistic models of authenticity judgments for artificially generated rap lyrics
- Carbon emission reduction and profit distribution mechanism of construction supply chain with fairness concern and cap-and-trade
- Modulations of microbehaviour by associative memory strength in Drosophila larvae
- Changes in peak expiratory flow rates using two head-tilt/chin-lift maneuver angles in young healthy conscious volunteers
- 3D image analysis reveals differences of CD30 positive cells and network formation in reactive and malignant human lymphoid tissue (classical Hodgkin Lymphoma)
- Change in larval fish assemblage in a USA east coast estuary estimated from twenty-six years of fixed weekly sampling
- 2-methylquinazoline derivative F7 as a potent and selective HDAC6 inhibitor protected against rhabdomyolysis-induced acute kidney injury
- Correction: Reducing growth and developmental problems in children: Development of an innovative postnatal risk assessment
- Comparative analysis of the vertebral pneumatization in pterosaurs (Reptilia: Pterosauria) and extant birds (Avialae: Neornithes)
- Associations between cognitive performance and sigma power during sleep in children with attention-deficit/hyperactivity disorder, healthy children, and healthy adults
- Retraction: MiR-375 Is Epigenetically Downregulated by HPV-16 E6 Mediated DNMT1 Upregulation and Modulates EMT of Cervical Cancer Cells by Suppressing lncRNA MALAT1
- Comparing growth patterns of three species: Similarities and differences
- Iron is increased in the brains of ageing mice lacking the neurofilament light gene
- Economic evaluation of community acquired pneumonia management strategies: A systematic review of literature
- A participatory community case study of periurban coastal flood vulnerability in southern Ecuador
- Chemotherapy-induced cellular senescence suppresses progression of Notch-driven T-ALL
- Mitochondrial dysfunctions in leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL)
- MRI-based visualization of rTMS-induced cortical plasticity in the primary motor cortex
- Knowledge, attitudes, and practices related to anthrax and animal care: A case-control study in Georgia
- Information diffusion in signed networks
- Nurses’ perspectives on their communication with patients in busy oncology wards: A qualitative study
- Inflammation in acute coronary syndrome: Expression of TLR2 mRNA is increased in platelets of patients with ACS
- ART is key to clearing oncogenic HPV genotypes (HR-HPV) in anal mucosa of HIV-positive MSM
- Retraction: Fluid–Structure Interaction-Based Biomechanical Perception Model for Tactile Sensing
- Correction: Role of Caveolin-1 in Atrial Fibrillation as an Anti-Fibrotic Signaling Molecule in Human Atrial Fibroblasts
- The French adaptation and validation of the Partners in Health (PIH) scale among patients with chronic conditions seen in primary care
- Depth inversion with a 3D structure influences brightness perception
- Analysis of group evolution prediction in complex networks
- Effect of aridity and dune type on rhizosphere soil bacterial communities of Caragana microphylla in desert regions of northern China
- Knowledge, attitudes, and practices related to TB among the general population of Ethiopia: Findings from a national cross-sectional survey
- Correction: Personality traits in companion dogs—Results from the VIDOPET
- MANET 3.0: Hierarchy and modularity in evolving metabolic networks
- Agreement study on gait assessment using a video-assisted rating method in patients with idiopathic normal-pressure hydrocephalus
- Single fixed low-dose rituximab as induction therapy suppresses de novo donor-specific anti-HLA antibody production in ABO compatible living kidney transplant recipients
- Myomesin is part of an integrity pathway that responds to sarcomere damage and disease
- Acute normobaric hypoxia does not affect the simultaneous exercise-induced increase in circulating BDNF and GDNF in young healthy men: A feasibility study
- Systematic investigation on quad-metallic AgAuPdPt and tri-metallic AuPdPt NPs through the solid-state dewetting of quad-layer Ag/Au/Pd/Pt thin films on c-plane sapphire
- Video lecturing in Clicker-assisted English flipped class
- Significant changes of the choroid in patients with ocular ischemic syndrome and symptomatic carotid artery stenosis
- Skewed T cell responses to Epstein-Barr virus in long-term asymptomatic kidney transplant recipients
- Candidate genes expression profiling during wilting in chickpea caused by Fusarium oxysporum f. sp. ciceris race 5
- Host plants influence the composition of the gut bacteria in Henosepilachna vigintioctopunctata
- ‘We are all serving the same Ugandans’: A nationwide mixed-methods evaluation of private sector surgical capacity in Uganda
- The association between flavor capsule cigarette use and sociodemographic variables: Evidence from Chile
- Relations between gross motor skills and executive functions, controlling for the role of information processing and lapses of attention in 8-10 year old children
- Linalool acts as a fast and reversible anesthetic in Hydra
- Double burden of maternal and child malnutrition and socioeconomic status in urban Sri Lanka
- Using isotemporal substitution to predict the effects of changing physical behaviour on older adults’ cardio-metabolic profiles
- Adherence to general medical checkup and cancer screening guidelines according to self-reported smoking status: Korea National Health and Nutrition Examination Survey (KNHANES) 2010–2012
- Do older English adults exhibit day-to-day compensation in sedentary time and in prolonged sedentary bouts? An EPIC-Norfolk cohort analysis
- Linoleic acid supplementation of cell culture media influences the phospholipid and lipid profiles of human reconstructed adipose tissue
- Correction: Factors associated with hospitalization and death among TB/HIV co-infected persons in Porto Alegre, Brazil
- An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
- Reporting adverse events related to medical devices: A single center experience from a tertiary academic hospital
- Enterohemorrhagic Escherichia coli infection inhibits colonic thiamin pyrophosphate uptake via transcriptional mechanism
- Estimating biodiversity changes in the Camargue wetlands: An expert knowledge approach
- Decreased risk of Parkinson’s disease in diabetic patients with thiazolidinediones therapy: An exploratory meta-analysis
- Retraction: Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis
- Lipoarabinomannan from Mycobacterium indicus pranii shows immunostimulatory activity and induces autophagy in macrophages
- A measure of inconsistencies in intertemporal choice
- A novel radiopaque tissue marker for soft tissue localization and in vivo length and area measurements
- Anatomical, histological and computed tomography comparisons of the eye and adnexa of crab-eating fox (Cerdocyon thous) to domestic dogs
- Subpopulation augmentation among habitat patches as a tool to manage an endangered Mojave Desert wetlands-dependent rodent during anthropogenic restricted water climate regimes
- Characteristics of CD5-positive diffuse large B-cell lymphoma among Koreans: High incidence of BCL2 and MYC double-expressors
- Fossil tabulate corals reveal outcrops of Paleozoic sandstones in the Atlantic Coastal Plain Province, Southeastern USA
- Coming and going – Historical distributions of the European oyster Ostrea edulis Linnaeus, 1758 and the introduced slipper limpet Crepidula fornicata Linnaeus, 1758 in the North Sea
- Behavioral predictors of subsequent respiratory illness signs in dogs admitted to an animal shelter
- Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation
- Can emotional intelligence be improved? A randomized experimental study of a business-oriented EI training program for senior managers
- Genetic variability in landraces populations and the risk to lose genetic variation. The example of landrace ‘Kyperounda’ and its implications for ex situ conservation
- Sleep problems are a strong predictor of stress-related metabolic changes in police officers. A prospective study
- Age, sex and primary care setting differences in patients’ perception of community healthcare seeking behaviour towards health services
- Kinematic analyses including finite helical axes of drop jump landings demonstrate decreased knee control long after anterior cruciate ligament injury
- Effects of model inaccuracies on reaching movements with intermittent control
- C-reactive protein to albumin ratio predicts the outcome in renal cell carcinoma: A meta-analysis
- A new synthetic lure for management of the invasive giant African snail, Lissachatina fulica
- Bridging solvent molecules mediate RNase A – Ligand binding
- Variation in methods, results and reporting in electronic health record-based studies evaluating routine care in gout: A systematic review
- The use of prophylactic intra-aortic balloon pump in high-risk patients undergoing coronary artery bypass grafting
- Compliance with clinical guidelines for breast cancer management: A population-based study of quality-of-care indicators in France
- Dysregulated T helper type 1 (Th1) and Th17 responses in elderly hospitalised patients with infection and sepsis
- Acute effects of differential learning on football kicking performance and in countermovement jump
- Escherichia coli and Salmonella spp. isolated from Australian meat chickens remain susceptible to critically important antimicrobial agents
- Play like me: Similarity in playfulness promotes social play
- Awareness of family health history in a predominantly young adult population
- Care pathways during a child’s final illness in rural South Africa: Findings from a social autopsy study
- Intranasal lidocaine for acute migraine: A meta-analysis of randomized controlled trials
- Evaluating case management as a complex intervention: Lessons for the future
- Allele-specific enhancer interaction at the Peg3 imprinted domain
- Has the “M” word been framed? Marijuana, cannabis, and public opinion
- Is spontaneous normalization of systolic blood pressure within 24 hours after ischemic stroke onset related with favorable outcomes?
- Mixotrophic cultivation of Spirulina platensis in dairy wastewater: Effects on the production of biomass, biochemical composition and antioxidant capacity
- Constitutive expression of an A-5 subgroup member in the DREB transcription factor subfamily from Ammopiptanthus mongolicus enhanced abiotic stress tolerance and anthocyanin accumulation in transgenic Arabidopsis
- Stable carbon isotope diagnostics of mammalian metabolism, a high-resolution isotomics approach using amino acid carboxyl groups
- Factors associated with depressive symptoms in patients with ankylosing spondylitis in Northern Taiwan
- A multicenter prospective study of 515 febrile neutropenia episodes in Argentina during a 5-year period
- Retraction: Reversal Effect of ST6GAL 1 on Multidrug Resistance in Human Leukemia by Regulating the PI3K/Akt Pathway and the Expression of P-gp and MRP1
- Potential role for microRNA-16 (miR-16) and microRNA-93 (miR-93) in diagnosis and prediction of disease progression in mycosis fungoides in Egyptian patients
- Rapid visual categorization is not guided by early salience-based selection
- Relative contribution of climate and non-climate drivers in determining dynamic rates of boreal birds at the edge of their range
- A simple-to-use nomogram to predict long term survival of patients undergoing coronary artery bypass grafting (CABG) using bilateral internal thoracic artery grafting technique
- Effects of sonication parameters on transcranial focused ultrasound brain stimulation in an ovine model
- Antenatal and intrapartum interventions for reducing caesarean section, promoting vaginal birth, and reducing fear of childbirth: An overview of systematic reviews
- Relative species abundance successfully predicts nestedness and interaction frequency of monthly pollination networks in an alpine meadow
- Correction: RCER: Reliable Cluster-based Energy-aware Routing protocol for heterogeneous Wireless Sensor Networks
- Amphibians on the hotspot: Molecular biology and conservation in the South American Atlantic Rainforest
- Role of psychosocial status in predicting health-related quality of life at 1-year follow-up among newly diagnosed people living with HIV
- Application of national pollutant inventories for monitoring trends on dioxin emissions from stationary industrial sources in Australia, Canada and European Union
- The association between vaccination confidence, vaccination behavior, and willingness to recommend vaccines among Finnish healthcare workers
- Retraction: Interleukin-1β-Induced Autophagy-Related Gene 5 Regulates Proliferation of Embryonic Stem Cell-Derived Odontoblastic Cells
- A localized sanitation status index as a proxy for fecal contamination in urban Maputo, Mozambique
- E2 protein is the major determinant of specificity at the human papillomavirus origin of replication
- “You’re kind of at war with yourself as a nurse”: Perspectives of inpatient nurses on treating people who present with a comorbid opioid use disorder
- A refinement approach in a mouse model of rehabilitation research. Analgesia strategy, reduction approach and infrared thermography in spinal cord injury
- Circulating cell-free DNA from plasma undergoes less fragmentation during bisulfite treatment than genomic DNA due to low molecular weight
- Understanding fatigue in adults with visual impairment: A path analysis study of sociodemographic, psychological and health-related factors
- Retraction: Mouse-Induced Pluripotent Stem Cells Differentiate into Odontoblast-Like Cells with Induction of Altered Adhesive and Migratory Phenotype of Integrin
- A novel analytical method to assess the effect of imipenem/cilastatin on liver function laboratory indexes in Chinese underage inpatients: Probability distribution curve
- The cause of anorexia and proportion of its recovery in older adults without underlying disease: Results of a retrospective study
- Referral and admission to intensive care: A qualitative study of doctors’ practices in a Tanzanian university hospital
- Agreement between clinical and non-clinical digital manometer for assessing maximal respiratory pressures in healthy subjects
- Heads or tails? Differential translational regulation in cercarial heads and tails of schistosome worms
- Horizontal seed dispersal by dung beetles reduced seed and seedling clumping, but did not increase short-term seedling establishment
- The coupling of the M2 muscarinic receptor to its G protein is voltage dependent
- Subsidy strategy of pharmaceutical e-commerce platform based on two-sided market theory
- Shoulder girdle injuries involving the medial clavicle differ from lateral clavicle injuries with a focus on concomitant injuries and management strategies: A retrospective study based on nationwide routine data
- Unraveling middle childhood attachment-related behavior sequences using a micro-coding approach
- Divergence history and hydrothermal vent adaptation of decapod crustaceans: A mitogenomic perspective
- Duration of solid fuel cookstove use is associated with increased risk of acute lower respiratory infection among children under six months in rural central India
- Evolving flocking in embodied agents based on local and global application of Reynolds’ rules
- Non-invasive contrast enhanced ultrasound molecular imaging of inflammation in autoimmune myocarditis for prediction of left ventricular fibrosis and remodeling
- Care coordination for chronic and complex health conditions: An experienced based co-design study engaging consumer and clinician groups for service improvement
- Association between socioeconomic status and diet quality in Mexican men and women: A cross-sectional study
- Surveillance of panicle positions by unmanned aerial vehicle to reveal morphological features of rice
- Is Betula carpatica genetically distinctive? A morphometric, cytometric and molecular study of birches in the Bohemian Massif with a focus on Carpathian birch
- Correction: Sequential analysis of myocardial gene expression with phenotypic change: Use of cross-platform concordance to strengthen biologic relevance
- The genome of the migratory nematode, Radopholus similis, reveals signatures of close association to the sedentary cyst nematodes
- Factors associated with pneumococcal carriage and density in infants and young children in Laos PDR
- Overlap between telangiectasia and photoreceptor loss increases with progression of macular telangiectasia type 2
- The role of hope for health professionals in rehabilitation: A qualitative study on unfavorable prognosis communication
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