#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

A new cascade of HIV care for the era of “treat all”


Matthew Fox and Sydney Rosen discuss a cascade of HIV care adapted to WHO-recommended antiretroviral therapy irrespective of CD4 cell count.


Vyšlo v časopise: A new cascade of HIV care for the era of “treat all”. PLoS Med 14(4): e32767. doi:10.1371/journal.pmed.1002268
Kategorie: Essay
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pmed.1002268

Souhrn

Matthew Fox and Sydney Rosen discuss a cascade of HIV care adapted to WHO-recommended antiretroviral therapy irrespective of CD4 cell count.


Zdroje

1. Greenberg A, Hader S, Masur H, Young A, Skillicorn J, Dieffenbach C. Fighting HIV/AIDS In Washington, D.C. Health Aff. 2009;28: 1677–1687.

2. Rosen S, Fox MP. Retention in HIV care between testing and treatment in sub-Saharan Africa: a systematic review. PLoS Med. 2011;8: e1001056. doi: 10.1371/journal.pmed.1001056 21811403

3. Gardner EM, McLees MP, Steiner JF, del Rio C, Burman WJ. The Spectrum of Engagement in HIV Care and its Relevance to Test-and-Treat Strategies for Prevention of HIV Infection. Clin Infect Dis. 2011;52: 793–800. doi: 10.1093/cid/ciq243 21367734

4. Mugglin C, Estill J, Wandeler G, Bender N, Egger M, Gsponer T, et al. Loss to programme between HIV diagnosis and initiation of antiretroviral therapy in sub-Saharan Africa: systematic review and meta-analysis. Trop Med Int Health. 2012;17: 1509–20. doi: 10.1111/j.1365-3156.2012.03089.x 22994151

5. Kranzer K, Govindasamy D, Ford N, Johnston V, Lawn SD. Quantifying and addressing losses along the continuum of care for people living with HIV infection in sub-Saharan Africa: a systematic review. J Int AIDS Soc. 2012;15: 17383. doi: 10.7448/IAS.15.2.17383 23199799

6. Plazy M, Orne-Gliemann J, Dabis F, Dray-Spira R. Retention in care prior to antiretroviral treatment eligibility in sub-Saharan Africa: a systematic review of the literature. BMJ Open. 2015;5: e006927. doi: 10.1136/bmjopen-2014-006927 26109110

7. World Health Organization. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection Recommendations for a public health approach—Second edition. Geneva, Switzerland; 2016.

8. UNAIDS. 90-90-90 An ambitious treatment target to help end the AIDS epidemic. Geneva, Switzerland; 2014. http://www.unaids.org/sites/default/files/media_asset/90-90-90_en_0.pdf

9. Fox MP, Rosen S. Retention of Adult Patients on Antiretroviral Therapy in Low- and Middle-Income Countries: Systematic Review and Meta-analysis 2008–2013. J Acquir Immune Defic Syndr. 2015;69: 98–108. doi: 10.1097/QAI.0000000000000553 25942461

10. Fox MP, Rosen S. Systematic review of retention of pediatric patients on HIV treatment in low and middle-income countries 2008–2013. AIDS. 2015;29: 493–502. doi: 10.1097/QAD.0000000000000559 25565496

11. Geng EH, Glidden D V, Bwana MB, Musinguzi N, Emenyonu N, Muyindike W, et al. Retention in care and connection to care among HIV-infected patients on antiretroviral therapy in Africa: estimation via a sampling-based approach. PLoS ONE. 2011;6: e21797. doi: 10.1371/journal.pone.0021797 21818265

12. Barnabas R V, van Rooyen H, Tumwesigye E, Murnane PM, Baeten JM, Humphries H, et al. Initiation of antiretroviral therapy and viral suppression after home HIV testing and counselling in KwaZulu-Natal, South Africa, and Mbarara district, Uganda: a prospective, observational intervention study. Lancet HIV. 2014;1: e68–e76. doi: 10.1016/S2352-3018(14)70024-4 25601912

13. MacPherson P, Lalloo DG, Webb EL, Maheswaran H, Choko AT, Makombe SD, et al. Effect of optional home initiation of HIV care following HIV self-testing on antiretroviral therapy initiation among adults in Malawi: a randomized clinical trial. JAMA. 2014;312: 372–9. doi: 10.1001/jama.2014.6493 25038356

14. Katz IT, Bangsberg DR. Cascade of Refusal—What Does It Mean for the Future of Treatment as Prevention in Sub-Saharan Africa? Curr HIV/AIDS Rep. 2016;13: 125–30. doi: 10.1007/s11904-016-0309-9 26894487

15. Amanyire G, Semitala FC, Namusobya J, Katuramu R, Kampiire L, Wallenta J, et al. Streamlining Antiretroviral Therapy Uptake: A Stepped-Wedge Cluster Randomized Trial. 23rd Conference on Retroviruses and Opportunistic Infections (CROI). Boston (Abstract 112); 2016.

16. Rosen S, Maskew M, Fox M, Nyoni D, Mongwenyana C, Malete G, et al. Initiating Antiretroviral Therapy for HIV at a Patient’s First Clinic Visit: The RapIT Randomized Controlled Trial. PLoS Med. 2016;13: e1002015. doi: 10.1371/journal.pmed.1002015 27163694

17. Wilkinson L, Duvivier H, Patten G, Solomon S, Mdani L, Patel S, et al. Outcomes from the implementation of a counselling model supporting rapid antiretroviral treatment initiation in a primary healthcare clinic in Khayelitsha, South Africa. South African J HIV Med. 2015;16: 1–7.

18. Kluberg SA, Fox MP, LaValley M, Bärnighausen T, Pillay D, Bor J. Do ART Eligibility Expansions Crowd out the Sickest? Evidence From South Africa. 23rd Conference on Retroviruses and Opportunistic Infections (CROI). Boston (Abstract 1012 Themed Discussion); 2016.

19. Avila D, Althoff KN, Mugglin C, Wools-Kaloustian K, Koller M, Dabis F, et al. Immunodeficiency at the start of combination antiretroviral therapy in low-, middle-, and high-income countries. J Acquir Immune Defic Syndr. 2014;65: e8–16. doi: 10.1097/QAI.0b013e3182a39979 24419071

20. Fox MP. Are we shifting attrition downstream in the HIV cascade? Lancet HIV. 2016;3: e554–e555. doi: 10.1016/S2352-3018(16)30149-7 27771232

21. Nachega JB, Uthman OA, del Rio C, Mugavero MJ, Rees H, Mills EJ. Addressing the Achilles’ Heel in the HIV Care Continuum for the Success of a Test-and-Treat Strategy to Achieve an AIDS-Free Generation. Clin Infect Dis. 2014;59: S21–S27. doi: 10.1093/cid/ciu299 24926028

22. Fox MP, Rosen S, Geldsetzer P, Bärnighausen T, Negussie E, Beanland R. Interventions to improve the rate or timing of initiation of antiretroviral therapy for HIV in sub-Saharan Africa: meta-analyses of effectiveness. J Int AIDS Soc. 2016;19: 20888 doi: 10.7448/IAS.19.1.20888 27507249

23. Govindasamy D, Ford N, Kranzer K. Risk factors, barriers and facilitators for linkage to antiretroviral therapy care. AIDS. 2012;26: 2059–2067. doi: 10.1097/QAD.0b013e3283578b9b 22781227

24. Siedner MJ, Lankowski A, Haberer JE, Kembabazi A, Emenyonu N, Tsai AC, et al. Rethinking the “pre” in pre-therapy counseling: no benefit of additional visits prior to therapy on adherence or viremia in Ugandans initiating ARVs. PLoS ONE. 2012;7: e39894. doi: 10.1371/journal.pone.0039894 22761924

25. Ford D, Muzambi M, Nkhata MJ, Abongomera G, Joseph S, Ndlovu M, et al. Implementation of antiretroviral therapy for life in pregnant/breastfeeding HIV+ women (Option B+) alongside rollout and changing guidelines for ART initiation in rural Zimbabwe: the Lablite Project experience. J Acquir Immune Defic Syndr. 2016; 1. E-pub ahead of print.

26. Clouse K, Pettifor A, Shearer K, Maskew M, Bassett J, Larson B, et al. Loss to follow-up before and after delivery among women testing HIV positive during pregnancy in Johannesburg, South Africa. Trop Med Int Health. 2013;18: 451–60. doi: 10.1111/tmi.12072 23374278

27. Hallett TB, Eaton JW. A side door into care cascade for HIV-infected patients? J Acquir Immune Defic Syndr. 2013;63 Suppl 2: S228–32.

28. World Health Organization. Prevent HIV, test and treat all—WHO support for country impact. Progress report 2016. Geneva, Switerland; 2016. http://www.who.int/hiv/pub/progressreports/2016-progress-report/en/.

Štítky
Interné lekárstvo

Článok vyšiel v časopise

PLOS Medicine


2017 Číslo 4
Najčítanejšie tento týždeň
Najčítanejšie v tomto čísle
Kurzy

Zvýšte si kvalifikáciu online z pohodlia domova

Získaná hemofilie - Povědomí o nemoci a její diagnostika
nový kurz

Eozinofilní granulomatóza s polyangiitidou
Autori: doc. MUDr. Martina Doubková, Ph.D.

Všetky kurzy
Prihlásenie
Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.

Prihlásenie

Nemáte účet?  Registrujte sa

#ADS_BOTTOM_SCRIPTS#