-
Články
- Časopisy
- Kurzy
- Témy
- Kongresy
- Videa
- Podcasty
Unmet Expectations: miR-34 Plays No Role in p53-Mediated Tumor Suppression In Vivo
article has not abstract
Vyšlo v časopise: Unmet Expectations: miR-34 Plays No Role in p53-Mediated Tumor Suppression In Vivo. PLoS Genet 8(7): e32767. doi:10.1371/journal.pgen.1002859
Kategorie: Perspective
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1002859Souhrn
article has not abstract
Zdroje
1. SpikeBT, WahlGM (2011) p53, stem cells, and reprogramming: tumor suppression beyond guarding the genome. Genes Cancer 2 : 404–419.
2. SoussiT (2007) p53 alterations in human cancer: more questions than answers. Oncogene 26 : 2145–2156.
3. HollsteinM, SidranskyD, VogelsteinB, HarrisCC (1991) p53 mutations in human cancers. Science 253 : 49–53.
4. HarveyM, McArthurMJ, MontgomeryCAJr, ButelJS, BradleyA, et al. (1993) Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice. Nat Genet 5 : 225–229.
5. JacksT, RemingtonL, WilliamsBO, SchmittEM, HalachmiS, et al. (1994) Tumor spectrum analysis in p53-mutant mice. Curr Biol : CB 4 : 1–7.
6. VousdenKH, PrivesC (2009) Blinded by the light: the growing complexity of p53. Cell 137 : 413–431.
7. SahVP, AttardiLD, MulliganGJ, WilliamsBO, BronsonRT, et al. (1995) A subset of p53-deficient embryos exhibit exencephaly. Nat Genet 10 : 175–180.
8. HuW, FengZ, TereskyAK, LevineAJ (2007) p53 regulates maternal reproduction through LIF. Nature 450 : 721–724.
9. MillsAA, ZhengB, WangXJ, VogelH, RoopDR, et al. (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398 : 708–713.
10. YangA, WalkerN, BronsonR, KaghadM, OosterwegelM, et al. (2000) p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature 404 : 99–103.
11. ConcepcionCP, HanY-C, MuP, BonettiC, YaoE, et al. (2012) Intact p53-dependent responses in miR-34-deficient mice. PloS Genet 8: e1002792 doi:10.1371/journal.pgen.1002797.
12. BommerGT, GerinI, FengY, KaczorowskiAJ, KuickR, et al. (2007) p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol 17 : 1298–1307.
13. HeL, HeX, LimLP, de StanchinaE, XuanZ, et al. (2007) A microRNA component of the p53 tumour suppressor network. Nature 447 : 1130–1134.
14. Raver-ShapiraN, MarcianoE, MeiriE, SpectorY, RosenfeldN, et al. (2007) Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol Cell 26 : 731–743.
15. ChangTC, WentzelEA, KentOA, RamachandranK, MullendoreM, et al. (2007) Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell 26 : 745–752.
16. TazawaH, TsuchiyaN, IzumiyaM, NakagamaH (2007) Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci U S A 104 : 15472–15477.
17. TarasovV, JungP, VerdoodtB, LodyginD, EpanchintsevA, et al. (2007) Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 6 : 1586–1593.
18. BartelDP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 : 281–297.
19. CalinGA, SevignaniC, DumitruCD, HyslopT, NochE, et al. (2004) Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 101 : 2999–3004.
20. HeL, HeX, LoweSW, HannonGJ (2007) microRNAs join the p53 network–another piece in the tumour-suppression puzzle. Nat Rev Cancer 7 : 819–822.
21. SpurgersKB, GoldDL, CoombesKR, BohnenstiehlNL, MullinsB, et al. (2006) Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression. J Biol Chem 281 : 25134–25142.
22. LeeKC, CroweAJ, BartonMC (1999) p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding. Mol Cell Biol 19 : 1279–1288.
23. LinT, ChaoC, SaitoS, MazurSJ, MurphyME, et al. (2005) p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol 7 : 165–171.
24. RileyT, SontagE, ChenP, LevineA (2008) Transcriptional control of human p53-regulated genes. Nat Rev Mol Cell Bio 9 : 402–412.
25. HoJ, BenchimolS (2003) Transcriptional repression mediated by the p53 tumour suppressor. Cell Death Differ 10 : 404–408.
26. LinCP, ChoiYJ, HicksGG, HeL (2012) The emerging functions of the p53-miRNA network in stem cell biology. Cell Cycle 11 : 2063–72.
27. VersteegR, CaronH, ChengNC, van der DriftP, SlaterR, et al. (1995) 1p36: every subband a suppressor? Eur J Cancer 31A: 538–541.
28. HermekingH (2010) The miR-34 family in cancer and apoptosis. Cell Death Differ 17 : 193–199.
29. HermekingH (2007) p53 enters the microRNA world. Cancer Cell 12 : 414–418.
30. ChoiYJ, LinCP, HoJJ, HeX, OkadaN, et al. (2011) miR-34 miRNAs provide a barrier for somatic cell reprogramming. Nat Cell Biol 13 : 1353–1360.
31. KrizhanovskyV, LoweSW (2009) Stem cells: The promises and perils of p53. Nature 460 : 1085–1086.
32. JainAK, AlltonK, IacovinoM, MahenE, MilczarekRJ, et al. (2012) p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells. PLoS Biol 10: e1001268 doi:10.1371/journal.pbio.1001268.
33. LeucciE, CoccoM, OnnisA, De FalcoG, van CleefP, et al. (2008) MYC translocation-negative classical Burkitt lymphoma cases: an alternative pathogenetic mechanism involving miRNA deregulation. J Pathol 216 : 440–450.
34. JiQ, HaoX, ZhangM, TangW, YangM, et al. (2009) MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PloS ONE 4: e6816 doi:10.1371/journal.pone.0006816.
35. CorneyDC, Flesken-NikitinA, GodwinAK, WangW, NikitinAY (2007) MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res 67 : 8433–8438.
36. WelchC, ChenY, StallingsRL (2007) MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene 26 : 5017–5022.
Štítky
Genetika Reprodukčná medicína
Článek Allelic Heterogeneity and Trade-Off Shape Natural Variation for Response to Soil MicronutrientČlánek The Chicken Frizzle Feather Is Due to an α-Keratin () Mutation That Causes a Defective RachisČlánek A Trans-Species Missense SNP in Is Associated with Sex Determination in the Tiger Pufferfish, (Fugu)
Článok vyšiel v časopisePLOS Genetics
Najčítanejšie tento týždeň
2012 Číslo 7- Gynekologové a odborníci na reprodukční medicínu se sejdou na prvním virtuálním summitu
- Je „freeze-all“ pro všechny? Odborníci na fertilitu diskutovali na virtuálním summitu
-
Všetky články tohto čísla
- Functional Evolution of Mammalian Odorant Receptors
- Oocyte Family Trees: Old Branches or New Stems?
- Allelic Heterogeneity and Trade-Off Shape Natural Variation for Response to Soil Micronutrient
- Guidelines for Genome-Wide Association Studies
- GWAS Identifies Novel Susceptibility Loci on 6p21.32 and 21q21.3 for Hepatocellular Carcinoma in Chronic Hepatitis B Virus Carriers
- DNA Methyltransferases Are Required to Induce Heterochromatic Re-Replication in Arabidopsis
- Genomic Data Reveal a Complex Making of Humans
- Let-7b/c Enhance the Stability of a Tissue-Specific mRNA during Mammalian Organogenesis as Part of a Feedback Loop Involving KSRP
- The Secreted Immunoglobulin Domain Proteins ZIG-5 and ZIG-8 Cooperate with L1CAM/SAX-7 to Maintain Nervous System Integrity
- RsfA (YbeB) Proteins Are Conserved Ribosomal Silencing Factors
- Gene Conversion Occurs within the Mating-Type Locus of during Sexual Reproduction
- The Chicken Frizzle Feather Is Due to an α-Keratin () Mutation That Causes a Defective Rachis
- Meta-Analysis of Genome-Wide Scans for Total Body BMD in Children and Adults Reveals Allelic Heterogeneity and Age-Specific Effects at the Locus
- Balancing Selection at the Tomato Guardee Gene Family Maintains Variation in Strength of Pathogen Defense
- Large-Scale Introgression Shapes the Evolution of the Mating-Type Chromosomes of the Filamentous Ascomycete
- OSD1 Promotes Meiotic Progression via APC/C Inhibition and Forms a Regulatory Network with TDM and CYCA1;2/TAM
- Intact p53-Dependent Responses in miR-34–Deficient Mice
- FANCJ/BACH1 Acetylation at Lysine 1249 Regulates the DNA Damage Response
- CED-10/Rac1 Regulates Endocytic Recycling through the RAB-5 GAP TBC-2
- Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity
- F-Box Protein Specificity for G1 Cyclins Is Dictated by Subcellular Localization
- The Gene Encodes a Nuclear Protein That Affects Alternative Splicing
- A Key Role for Chd1 in Histone H3 Dynamics at the 3′ Ends of Long Genes in Yeast
- Genome-Wide Association Analysis in Asthma Subjects Identifies as a Novel Bronchodilator Response Gene
- GRHL3/GET1 and Trithorax Group Members Collaborate to Activate the Epidermal Progenitor Differentiation Program
- Brain-Specific Rescue of Reveals System-Driven Transcriptional Rhythms in Peripheral Tissue
- Recent Loss of Self-Incompatibility by Degradation of the Male Component in Allotetraploid
- Pregnancy-Induced Noncoding RNA () Associates with Polycomb Repressive Complex 2 and Regulates Mammary Epithelial Differentiation
- The HEI10 Is a New ZMM Protein Related to Zip3
- The SCF Ubiquitin E3 Ligase Ubiquitylates Sir4 and Functions in Transcriptional Silencing
- Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways
- Role of Architecture in the Function and Specificity of Two Notch-Regulated Transcriptional Enhancer Modules
- Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway
- A Regulatory Loop Involving PAX6, MITF, and WNT Signaling Controls Retinal Pigment Epithelium Development
- The Three Faces of Riboviral Spontaneous Mutation: Spectrum, Mode of Genome Replication, and Mutation Rate
- Unmet Expectations: miR-34 Plays No Role in p53-Mediated Tumor Suppression In Vivo
- A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone–Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation
- The Role of Rice HEI10 in the Formation of Meiotic Crossovers
- A Trans-Species Missense SNP in Is Associated with Sex Determination in the Tiger Pufferfish, (Fugu)
- Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk
- Evidence of Inbreeding Depression on Human Height
- Comparative Genomics of Plant-Associated spp.: Insights into Diversity and Inheritance of Traits Involved in Multitrophic Interactions
- Detecting Individual Sites Subject to Episodic Diversifying Selection
- Regulates Rhodopsin-1 Metabolism and Is Required for Photoreceptor Neuron Survival
- Identification of Chromatin-Associated Regulators of MSL Complex Targeting in Dosage Compensation
- Three Dopamine Pathways Induce Aversive Odor Memories with Different Stability
- TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in
- Rapid Turnover of Long Noncoding RNAs and the Evolution of Gene Expression
- The Yeast Rab GTPase Ypt1 Modulates Unfolded Protein Response Dynamics by Regulating the Stability of RNA
- Histone H2B Monoubiquitination Facilitates the Rapid Modulation of Gene Expression during Arabidopsis Photomorphogenesis
- Cellular Variability of RpoS Expression Underlies Subpopulation Activation of an Integrative and Conjugative Element
- Genetic Variants in , , and Influence Male Recombination in Cattle
- Differential Impact of the HEN1 Homolog HENN-1 on 21U and 26G RNAs in the Germline of
- PLOS Genetics
- Archív čísel
- Aktuálne číslo
- Informácie o časopise
Najčítanejšie v tomto čísle- Guidelines for Genome-Wide Association Studies
- The Role of Rice HEI10 in the Formation of Meiotic Crossovers
- Identification of Chromatin-Associated Regulators of MSL Complex Targeting in Dosage Compensation
- GWAS Identifies Novel Susceptibility Loci on 6p21.32 and 21q21.3 for Hepatocellular Carcinoma in Chronic Hepatitis B Virus Carriers
Prihlásenie#ADS_BOTTOM_SCRIPTS#Zabudnuté hesloZadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.
- Časopisy