Hereditary angioedema as a cause of abdominal pain

Česká verzia

Authors: K. Hrubišková; P. Jackuliak; J. Payer
Authors place of work: V. interná klinika LF UK a UN Bratislava, SR
Published in the journal: Gastroent Hepatol 2014; 68(2): 149-153
Category: Klinická a experimentální gastroenterologie: přehledová práce

Summary

Hereditary angioedema is a rare disease that may have potentially fatal consequences. Despite the fact that recently there is a deeper understanding of the pathophysiology of the disease, it is still a diagnostic challenge. The average time from the start of symptoms to the diagnosis is in avarage 10 to 25 years. The problem is the wide variety of clinical symptoms affecting various organ systems, the progress of the disease in attacks, and also a lack of awaraness of this disease in medical professionals. The aim of this article is to review the pathofysiology, the clinical picture and briefly the current treatment options. The authors also present a case report of a young female patient with a typical clinical picture of hereditary angioedema.

Key words:
hereditary angioedema – C1 inhibitor – edema

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE „uniform requirements“ for biomedical papers.

Submitted:
20. 1. 2014

Accepted:
8. 3. 2014

Zdroje

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