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From an old drug to a new one: Synthesis of valproate from 5,5-dipropylbarbituric acid


Autoři: Oldřich Farsa;  Pavol Brka
Působiště autorů: Department of Chemical Drugs, Faculty of Pharmacy University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic
Vyšlo v časopise: Čes. slov. Farm., 2015; 64, 287-288
Kategorie: 44<sup>th</sup> Conference drug synthesis and analysis


Zdroje

1. Addictive Compounds Act No. 167/1998 Coll.

2. Government Regulation Concerning the lists of Addictive Compounds No. 463/2013 Coll.

3. Aspelund H., Skoglund L. The stability of the sodium salts of some soporifics of the barbituric acid series in solution. Acta Acad. Aboensis Math. et Phys. 1937; 10, 14–36.

4. Mokrosz J., Bojarski J. Hydrolysis of barbituric acid derivatives. Part IV. Hydrolysis of derivatives without a shielding steric effect. Polish Journal of Chemistry 1982; 56, 491–500.

5. Helavi V. B., Solabannavar S. B., Desai U. V., Mane R. B. Microwave assisted hydrolysis of Meldrum’s acid derivatives and decarboxylation of derived malonic acids. J. Chem. Research (S), 2003; 2003, 174–175.

6. Toussaint O., Capdevielle P., Maumy M. The Copper(I)-Catalyzed Decarboxylation of Malonic Acids; A New Mild and Quantitative Method. Synthesis 1986; 1986. 1029–1031.

7. Barton H., Mokrosz J., Bojarski J., Klimczak M. Photochemical degradation of barbituric acid derivatives. Part 1. Products of photolysis and hydrolysis of pentobarbital. Pharmazie 1980; 35, 155–158.

Štítky
Farmácia Farmakológia

Článok vyšiel v časopise

Česká a slovenská farmacie

Číslo 6

2015 Číslo 6

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