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Phenotypic Screens, Chemical Genomics, and Antimalarial Lead Discovery

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Vyšlo v časopise: Phenotypic Screens, Chemical Genomics, and Antimalarial Lead Discovery. PLoS Pathog 7(8): e32767. doi:10.1371/journal.ppat.1002156
Kategorie: Opinion
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.ppat.1002156

Souhrn

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Zdroje

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3. PlouffeDBrinkerAMcNamaraCHensonKKatoN 2008 In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proc Natl Acad Sci U S A 105 9059 9064

4. LipinskiCA 2000 Drug-like properties and the causes of poor solubility and poor permeability. J Pharmacol Toxicol Methods 44 235 249

5. LipinskiCALombardoFDominyBWFeeneyPJ 2001 Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 46 3 26

6. StrobelGLArnoldJ 2004 Essential eukaryotic core. Evolution 58 441 446

7. BajorathJ 2008 Computational analysis of ligand relationships within target families. Curr Opin Chem Biol 12 352 358

8. KolbPFerreiraRSIrwinJJShoichetBK 2009 Docking and chemoinformatic screens for new ligands and targets. Curr Opin Biotechnol 20 429 436

9. KeiserMJSetolaVIrwinJJLaggnerCAbbasAI 2009 Predicting new molecular targets for known drugs. Nature 462 175 181

10. CrowtherGJNapuliAJGilliganJHGagaringKBorboaR 2011 Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds. Mol Biochem Parasitol 175 21 29

11. DujonB 1998 European Functional Analysis Network (EUROFAN) and the functional analysis of the Saccharomyces cerevisiae genome. Electrophoresis 19 617 624

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Článok vyšiel v časopise

PLOS Pathogens

2011 Číslo 8

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Autori: doc. MUDr. Martina Doubková, Ph.D.

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