#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials


In a systematic review and metanalysis, Harsha Shanthanna and colleagues examine the evidence for the benefits and safety of gabapentoids for chronic low back pain.


Vyšlo v časopise: Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials. PLoS Med 14(8): e32767. doi:10.1371/journal.pmed.1002369
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pmed.1002369

Souhrn

In a systematic review and metanalysis, Harsha Shanthanna and colleagues examine the evidence for the benefits and safety of gabapentoids for chronic low back pain.


Zdroje

1. Deyo RA, Weinstein JN. Low back pain. The New England journal of medicine. 2001;344(5):363–70. doi: 10.1056/NEJM200102013440508 11172169

2. Hooten WM, Cohen SP. Evaluation and Treatment of Low Back Pain: A Clinically Focused Review for Primary Care Specialists. Mayo Clin Proc. 2015;90(12):1699–718. doi: 10.1016/j.mayocp.2015.10.009 26653300

3. Hoy D, Bain C, Williams G, March L, Brooks P, Blyth F, et al. A systematic review of the global prevalence of low back pain. Arthritis Rheum. 2012;64(6):2028–37. doi: 10.1002/art.34347 22231424

4. Morlion B. Chronic low back pain: pharmacological, interventional and surgical strategies. Nature reviews Neurology. 2013;9(8):462–73. doi: 10.1038/nrneurol.2013.130 23817349

5. Shanthanna H, Gilron I, Thabane L, Devereaux PJ, Bhandari M, AlAmri R, et al. Gabapentinoids for chronic low back pain: a protocol for systematic review and meta-analysis of randomised controlled trials. BMJ open. 2016;6(11).

6. Chou R, Huffman LH. Medications for acute and chronic low back pain: a review of the evidence for an American Pain Society/American College of Physicians clinical practice guideline. Ann Intern Med. 2007;147(7):505–14. 17909211

7. White AP, Arnold PM, Norvell DC, Ecker E, Fehlings MG. Pharmacologic management of chronic low back pain: synthesis of the evidence. Spine. 2011;36(21 Suppl):S131–43. 21952185

8. Patel R, Dickenson AH. Mechanisms of the gabapentinoids and alpha 2 delta-1 calcium channel subunit in neuropathic pain. Pharmacol Res Perspect. 2016;4(2):e00205. doi: 10.1002/prp2.205 27069626

9. Maizels M, McCarberg B. Antidepressants and antiepileptic drugs for chronic non-cancer pain. Am Fam Physician. 2005;71(3):483–90. 15712623

10. Moore RA, Straube S, Wiffen PJ, Derry S, McQuay HJ. Pregabalin for acute and chronic pain in adults. Cochrane Database Syst Rev. 2009(3):Cd007076. doi: 10.1002/14651858.CD007076.pub2 19588419

11. Chaparro LE, Smith SA, Moore RA, Wiffen PJ, Gilron I. Pharmacotherapy for the prevention of chronic pain after surgery in adults. Cochrane Database Syst Rev. 2013(7):Cd008307. doi: 10.1002/14651858.CD008307.pub2 23881791

12. Mack A. Examination of the evidence for off-label use of gabapentin. J Manag Care Pharm. 2003;9(6):559–68. doi: 10.18553/jmcp.2003.9.6.559 14664664

13. Public Health England and National Health Services, UK. Advice for prescribers on the risk of the misuse of pregabalin and gabapentin. https://www.gov.uk/government/publications/pregabalin-and-gabapentin-advice-for-prescribers-on-the-risk-of-misuse. First published 14 December 2014. Last accessed 22 January, 2017.

14. Dworkin RH, Turk DC, Farrar JT, Haythornthwaite JA, Jensen MP, Katz NP, et al. Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain. 2005;113(1–2):9–19. doi: 10.1016/j.pain.2004.09.012 15621359

15. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. International journal of surgery (London, England). 2010;8(5):336–41.

16. Viera AJ, Garrett JM. Understanding interobserver agreement: the kappa statistic. Family medicine. 2005;37(5):360–3. 15883903

17. Schandelmaier S, Ebrahim S, Burkhardt SC, de Boer WE, Zumbrunn T, Guyatt GH, et al. Return to work coordination programmes for work disability: a meta-analysis of randomised controlled trials. PLoS ONE. 2012;7(11):e49760. doi: 10.1371/journal.pone.0049760 23185429

18. Higgins JPT G S. Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0 The Cochrane Collaboration: The Cochrane Collaboration; 2011. Last accessed 22 January 2017. http://handbook.cochrane.org/

19. Chan AW, Altman DG. Identifying outcome reporting bias in randomised trials on PubMed: review of publications and survey of authors. BMJ (Clinical research ed). 2005;330(7494):753.

20. Andrew Moore R, Eccleston C, Derry S, Wiffen P, Bell RF, Straube S, et al. "Evidence" in chronic pain—establishing best practice in the reporting of systematic reviews. Pain. 2010;150(3):386–9. 20627575

21. Ioannidis JP, Cappelleri JC, Lau J. Issues in comparisons between meta-analyses and large trials. Jama. 1998;279(14):1089–93. 9546568

22. Sterne JA, Gavaghan D, Egger M. Publication and related bias in meta-analysis: power of statistical tests and prevalence in the literature. Journal of clinical epidemiology. 2000;53(11):1119–29. 11106885

23. Ebrahim S, Johnston BC, Akl EA, Mustafa RA, Sun X, Walter SD, et al. Addressing continuous data measured with different instruments for participants excluded from trial analysis: a guide for systematic reviewers. J Clin Epidemiol 2014 May;67(5):560–70. doi: 10.1016/j.jclinepi.2013.11.014 24613497

24. Akl EA, Johnston BC, Alonso-Coello P, Neumann I, Ebrahim S, Briel M, et al. Addressing dichotomous data for participants excluded from trial analysis: a guide for systematic reviewers. PLoS ONE. 2013;8(2):e57132. doi: 10.1371/journal.pone.0057132 23451162

25. Atkinson JH, Slater MA, Capparelli EV, Patel SM, Wolfson T, Gamst A, et al. A randomized controlled trial of gabapentin for chronic low back pain with and without a radiating component. Pain. 2016;157(7):1499–507. doi: 10.1097/j.pain.0000000000000554 26963844

26. McCleane GJ. Gabapentin reduces chronic benign nociceptive pain: a double-blind, placebo-controlled cross-over study. The Pain Clinic. 2000;12(2):81–5.

27. McCleane GJ. Does gabapentin have an analgesic effect on background, movement and referred pain? A randomised, double-blind, placebo controlled study. The Pain Clinic. 2001;13(2):103–7.

28. Baron R, Martin-Mola E, Muller M, Dubois C, Falke D, Steigerwald I. Effectiveness and Safety of Tapentadol Prolonged Release (PR) Versus a Combination of Tapentadol PR and Pregabalin for the Management of Severe, Chronic Low Back Pain With a Neuropathic Component: A Randomized, Double-blind, Phase 3b Study. Pain Pract. 2015;15(5):455–70. doi: 10.1111/papr.12200 24738609

29. Kalita J, Kohat AK, Misra UK, Bhoi SK. An open labeled randomized controlled trial of pregabalin versus amitriptyline in chronic low backache. J Neurol Sci. 2014;342(1–2):127–32. doi: 10.1016/j.jns.2014.05.002 24857356

30. Pota V, Barbarisi M, Sansone P, Moraci M, Pace MC, Passavanti MB, et al. Combination therapy with transdermal buprenorphine and pregabalin for chronic low back pain. Pain Manag. 2012;2(1):23–31. doi: 10.2217/pmt.11.71 24654615

31. Romano CL, Romano D, Bonora C, Mineo G. Pregabalin, celecoxib, and their combination for treatment of chronic low-back pain. J Orthop Traumatol. 2009;10(4):185–91. doi: 10.1007/s10195-009-0077-z 19921480

32. Sakai Y, Ito K, Hida T, Ito S, Harada A. Pharmacological management of chronic low back pain in older patients: a randomized controlled trial of the effect of pregabalin and opioid administration. European spine journal: official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2015;24(6):1309–17.

33. Morlion B. Pharmacotherapy of low back pain: targeting nociceptive and neuropathic pain components. Current medical research and opinion. 2011;27(1):11–33. doi: 10.1185/03007995.2010.534446 21083513

34. Chiappini S, Schifano F. A Decade of Gabapentinoid Misuse: An Analysis of the European Medicines Agency's 'Suspected Adverse Drug Reactions' Database. CNS drugs. 2016;30(7):647–54. doi: 10.1007/s40263-016-0359-y 27312320

35. Bezerra DM, El Dib R, Vidal EIO, De Barros GAM, Chou R, Fukushima F. Anticonvulsants for chronic low-back pain. Cochrane Database of Systematic Reviews. 2014(6). CD011171

36. Tetsunaga T, Tetsunaga T, Tanaka M, Sugimoto Y, Takigawa T, Ozaki T. Outcomes of pregabalin in lumbar-disease patients with depression. Journal of orthopaedic science: official journal of the Japanese Orthopaedic Association. 2014;19(2):229–34.

37. Sakai Y, Ito K, Hida T, Ito S, Harada A. Neuropathic pain in elderly patients with chronic low back painand effects of pregabalin: a preliminary study. Asian spine journal. 2015;9(2):254–62. doi: 10.4184/asj.2015.9.2.254 25901238

38. Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, et al. Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol. 2015;14(2):162–73. doi: 10.1016/S1474-4422(14)70251-0 25575710

39. Simunovic M, Baxter NN. Knowledge translation research: a review and new concepts from a surgical case study. Surgery. 2009;145(6):639–44. doi: 10.1016/j.surg.2008.11.011 19486766

40. Giladi H, Choinière M, Fitzcharles M-A, Ware MA, Tan X, Shir Y. Pregabalin for chronic pain: does one medication fit all? Current medical research and opinion. 2015;31(7):1403–11. doi: 10.1185/03007995.2015.1040750 25868712

41. Baron R, Binder A, Attal N, Casale R, Dickenson AH, Treede RD. Neuropathic low back pain in clinical practice. Eur J Pain. 2016; 20(6): 861–873. doi: 10.1002/ejp.838 26935254

42. Taguchi T, Igarashi A, Watt S, Parsons B, Sadosky A, Nozawa K, et al. Effectiveness of pregabalin for the treatment of chronic low back pain with accompanying lower limb pain (neuropathic component): a non-interventional study in Japan. J Pain Res. 2015;8:487–97. doi: 10.2147/JPR.S88642 26346468

43. Orita S, Yamashita M, Eguchi Y, Suzuki M, Inoue G, Miyagi M, et al. Pregabalin for Refractory Radicular Leg Pain due to Lumbar Spinal Stenosis: A Preliminary Prospective Study. Pain Research and Management. 2016;2016:10.

44. Baron R, Freynhagen R, Tolle TR, Cloutier C, Leon T, Murphy TK, et al. The efficacy and safety of pregabalin in the treatment of neuropathic pain associated with chronic lumbosacral radiculopathy. Pain. 2010;150(3):420–7. doi: 10.1016/j.pain.2010.04.013 20493632

45. Markman JD, Frazer ME, Rast SA, McDermott MP, Gewandter JS, Chowdhry AK, et al. Double-blind, randomized, controlled, crossover trial of pregabalin for neurogenic claudication. Neurology. 2015;84(3):265–72. doi: 10.1212/WNL.0000000000001168 25503625

46. Cohen SP, Hanling S, Bicket MC, White RL, Veizi E, Kurihara C, et al. Epidural steroid injections compared with gabapentin for lumbosacral radicular pain: multicenter randomized double blind comparative efficacy study. BMJ: British Medical Journal. 2015;350:h1748. doi: 10.1136/bmj.h1748 25883095

47. Thorlund K, Imberger G, Johnston BC, Walsh M, Awad T, Thabane L, et al. Evolution of heterogeneity (I2) estimates and their 95% confidence intervals in large meta-analyses. PLoS ONE. 2012;7(7):e39471. doi: 10.1371/journal.pone.0039471 22848355

48. Muehlbacher M, Nickel MK, Kettler C, Tritt K, Lahmann C, Leiberich PK, et al. Topiramate in treatment of patients with chronic low back pain: a randomized, double-blind, placebo-controlled study. Clin J Pain. 2006;22(6):526–31. 16788338

49. Spence D. Bad medicine: gabapentin and pregabalin. BMJ (Clinical research ed). 2013;347:f6747.

50. Mathieson S, Maher CG, McLachlan AJ, Latimer J, Koes BW, Hancock MJ, et al. PRECISE—pregabalin in addition to usual care for sciatica: study protocol for a randomised controlled trial. Trials. 2013;14(1):213.

51. Clinical Trials Registry. https://clinicaltrials.gov/ct2/show/NCT02273908. Last accessed 22 January, 2017.

52. Clinical Trials Registry. https://www.clinicaltrials.gov/ct2/show/NCT01298466. Last accessed 22 January, 2017.

Štítky
Interné lekárstvo

Článok vyšiel v časopise

PLOS Medicine


2017 Číslo 8
Najčítanejšie tento týždeň
Najčítanejšie v tomto čísle
Kurzy

Zvýšte si kvalifikáciu online z pohodlia domova

Získaná hemofilie - Povědomí o nemoci a její diagnostika
nový kurz

Eozinofilní granulomatóza s polyangiitidou
Autori: doc. MUDr. Martina Doubková, Ph.D.

Všetky kurzy
Prihlásenie
Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.

Prihlásenie

Nemáte účet?  Registrujte sa

#ADS_BOTTOM_SCRIPTS#