Scaling Up Diarrhea Prevention and Treatment Interventions: A Lives Saved
Tool Analysis
Background:
Diarrhea remains a leading cause of mortality among young children in low- and
middle-income countries. Although the evidence for individual diarrhea prevention
and treatment interventions is solid, the effect a comprehensive scale-up effort
would have on diarrhea mortality has not been estimated.
Methods and Findings:
We use the Lives Saved Tool (LiST) to estimate the potential
lives saved if two scale-up scenarios for key diarrhea interventions (oral
rehydration salts [ORS], zinc, antibiotics for dysentery, rotavirus
vaccine, vitamin A supplementation, basic water, sanitation, hygiene, and
breastfeeding) were implemented in the 68 high child mortality countries. We also
conduct a simple costing exercise to estimate cost per capita and total costs for
each scale-up scenario. Under the ambitious (feasible improvement in coverage of
all interventions) and universal (assumes near 100% coverage of all
interventions) scale-up scenarios, we demonstrate that diarrhea mortality can be
reduced by 78% and 92%, respectively. With universal coverage nearly
5 million diarrheal deaths could be averted during the 5-year scale-up period for
an additional cost of US$12.5 billion invested across 68 priority countries
for individual-level prevention and treatment interventions, and an additional
US$84.8 billion would be required for the addition of all water and
sanitation interventions.
Conclusion:
Using currently available interventions, we demonstrate that with improved
coverage, diarrheal deaths can be drastically reduced. If delivery strategy
bottlenecks can be overcome and the international community can collectively
deliver on the key strategies outlined in these scenarios, we will be one step
closer to achieving success for the United Nations' Millennium Development
Goal 4 (MDG4) by 2015.
:
Please see later in the article for the Editors' Summary
Vyšlo v časopise:
Scaling Up Diarrhea Prevention and Treatment Interventions: A Lives Saved
Tool Analysis. PLoS Med 8(3): e32767. doi:10.1371/journal.pmed.1000428
Kategorie:
Research Article
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.pmed.1000428
Souhrn
Background:
Diarrhea remains a leading cause of mortality among young children in low- and
middle-income countries. Although the evidence for individual diarrhea prevention
and treatment interventions is solid, the effect a comprehensive scale-up effort
would have on diarrhea mortality has not been estimated.
Methods and Findings:
We use the Lives Saved Tool (LiST) to estimate the potential
lives saved if two scale-up scenarios for key diarrhea interventions (oral
rehydration salts [ORS], zinc, antibiotics for dysentery, rotavirus
vaccine, vitamin A supplementation, basic water, sanitation, hygiene, and
breastfeeding) were implemented in the 68 high child mortality countries. We also
conduct a simple costing exercise to estimate cost per capita and total costs for
each scale-up scenario. Under the ambitious (feasible improvement in coverage of
all interventions) and universal (assumes near 100% coverage of all
interventions) scale-up scenarios, we demonstrate that diarrhea mortality can be
reduced by 78% and 92%, respectively. With universal coverage nearly
5 million diarrheal deaths could be averted during the 5-year scale-up period for
an additional cost of US$12.5 billion invested across 68 priority countries
for individual-level prevention and treatment interventions, and an additional
US$84.8 billion would be required for the addition of all water and
sanitation interventions.
Conclusion:
Using currently available interventions, we demonstrate that with improved
coverage, diarrheal deaths can be drastically reduced. If delivery strategy
bottlenecks can be overcome and the international community can collectively
deliver on the key strategies outlined in these scenarios, we will be one step
closer to achieving success for the United Nations' Millennium Development
Goal 4 (MDG4) by 2015.
:
Please see later in the article for the Editors' Summary
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