Ovarian Cancer: A Clinical Challenge That Needs Some Basic Answers

1. LeviFLucchiniFNegriEBoylePLa VecchiaC

2004

Cancer mortality in Europe, 1995–1999, and an overview of trends since 1960.

Int J Cancer

110

155

169

2. KöbelMKallogerSEBoydNMcKinneySMehlE

2008

Ovarian carcinoma subtypes are different diseases: Implications for biomarker studies.

PLoS Med

5

e232

doi:10.1371/journal.pmed.0050232

3. KurmanRJShihIeM

2008

Pathogenesis of ovarian cancer: Lessons from morphology and molecular biology and their clinical implications.

Int J Gynecol Pathol

27

151

160

4. McCluggageWG

2008

My approach to and thoughts on the typing of ovarian carcinomas.

J Clin Pathol

61

152

163

5. ZornKKBonomeTGangiLChandramouliGVAwtreyCS

2005

Gene expression profiles of serous, endometrioid, and clear cell subtypes of ovarian and endometrial cancer.

Clin Cancer Res

11

6422

6430

6. Sainz de la CuestaREichhornJHRiceLWFullerAFJrNikruiN

1996

Histologic transformation of benign endometriosis to early epithelial ovarian cancer.

Gynecol Oncol

60

238

244

7. MokSCKwongJWelchWRSamimiGOzbunL

2007

Etiology and pathogenesis of epithelial ovarian cancer.

Dis Markers

367

376

8. JarboeEFolkinsANucciMRKindelbergerDDrapkinR

2008

Serous carcinogenesis in the fallopian tube: A descriptive classification.

Int J Gynecol Pathol

27

1

9

9. CrijnsAPGFehrmannRSNde JongSGerbensFMeersmaGJ

2009

Survival-related profile, pathways, and transcription factors in ovarian cancer.

PLoS Med

6

e1000024

doi:10.1371/journal.pmed.1000024

10. van de VijverMJHeYDvan't VeerLJDaiHHartAA

2002

A gene-expression signature as a predictor of survival in breast cancer.

N Engl J Med

347

1999

2009

11. IsraeliOGoldring-AviramARiensteinSBen-BaruchGKorachJ

2005

In silico chromosomal clustering of genes displaying altered expression patterns in ovarian cancer.

Cancer Genet Cytogenet

160

35

42

12. TinkerAVBoussioutasABowtellDD

2006

The challenges of gene expression microarrays for the study of human cancer.

Cancer Cell

9

333

339

13. BuyseMLoiSvan't VeerLVialeGDelorenziM

2006

Validation and clinical utility of a 70-gene prognostic signature for women with node negative breast cancer.

J Natl Cancer Inst

98

1183

1192

14. DesmedtCPietteFLoiSWangYLallemandF

2007

Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series.

Clin Cancer Res

13

3207

3214

15. SotiriouCPiccartMJ

2007

Taking gene-expression profiling to the clinic: When will molecular signatures become relevant to patient care?

Nat Rev Cancer

7

545

553