Autoimmune Responses in the Rheumatoid Synovium

1. TakemuraSBraunACrowsonCKurtinPJCofieldRH

2001

Lymphoid neogenesis in rheumatoid synovitis.

J Immunol

167

1072

1080

2. AloisiFPujol-BorrellR

2006

Lymphoid neogenesis in chronic inflammatory diseases.

Nat Rev Immunol

6

205

217

3. Girbal-NeuhauserEDurieuxJJArnaudMDalbonPSebbagM

1999

The epitopes targeted by the rheumatoid arthritis-associated antifilaggrin autoantibodies are posttranslationally generated on various sites of (pro)filaggrin by deimination of arginine residues.

J Immunol

162

585

594

4. SchellekensGAde JongBAvan den HoogenFHvan de PutteLBvan VenrooijWJ

1998

Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies.

J Clin Invest

101

273

281

5. NielenMMvanSDReesinkHWvan de StadtRJvan der Horst-BruinsmaIE

2004

Specific autoantibodies precede the symptoms of rheumatoid arthritis: A study of serial measurements in blood donors.

Arthritis Rheum

50

380

386

6. ZendmanAJvan VenrooijWJPruijnGJ

2006

Use and significance of anti-CCP autoantibodies in rheumatoid arthritis.

Rheumatology (Oxford)

45

20

25

7. KuhnKAKulikLTomookaBBraschlerKJArendWP

2006

Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis.

J Clin Invest

116

961

973

8. van GaalenFALinn-RaskerSPvan VenrooijWJde JongBABreedveldFC

2004

Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis: A prospective cohort study.

Arthritis Rheum

50

709

715

9. van GaalenFIoan-FacsinayAHuizingaTWToesRE

2005

The devil in the details: The emerging role of anticitrulline autoimmunity in rheumatoid arthritis.

J Immunol

175

5575

5580

10. Masson-BessiereCSebbagMDurieuxJJNogueiraLVincentC

2000

In the rheumatoid pannus, anti-filaggrin autoantibodies are produced by local plasma cells and constitute a higher proportion of IgG than in synovial fluid and serum.

Clin Exp Immunol

119

544

552

11. Iwaki-EgawaSMatsunoHOgawaYWatanabeY

2005

Production of anti-CCP antibodies and matrix metalloproteinase-3 by human rheumatoid arthritis synovial tissues using SCID mice.

Ann Rheum Dis

64

1094

1095

12. HumbyFBombardieriMManzoAKellySBladesMC

2009

Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium.

PLoS Med

6

e1

doi:10.1371/journal.pmed.0060001

13. VerpoortKNJol-van der ZijdeCMPapendrecht-van der VoortEAIoan-FacsinayADrijfhoutJW

2006

Isotype distribution of anti-cyclic citrullinated peptide antibodies in undifferentiated arthritis and rheumatoid arthritis reflects an ongoing immune response.

Arthritis Rheum

54

3799

3808

14. CantaertTKollnJTimmerTvan der Pouw KraanTCVandoorenB

2008

B lymphocyte autoimmunity in rheumatoid synovitis is independent of ectopic lymphoid neogenesis.

J Immunol

181

785

794