How Might Cocaine Interfere with Brain Development?

1. ChiribogaCAKuhnLWassermanGA

2007

Prenatal cocaine exposures and dose-related cocaine effects on infant tone and behavior.

Neurotoxicol Teratol

29

323

330

2. SingerLTArendtRMinnesSFarkasKSalvatorA

2002

Cognitive and motor outcomes of cocaine-exposed infants.

JAMA

287

1952

1960

3. NolandJSSingerLTShortEJMinnesSArendtRE

2005

Prenatal drug exposure and selective attention in preschoolers.

Neurotoxicol Teratol

27

429

438

4. LeeC-TChenJHayashiTTsaiS-YSanchezJF

2008

A mechanism responsible for the inhibition of neural progenitor cell proliferation by cocaine.

PLoS Med

5

e117

doi:10.1371/journal.pmed.0050117

5. MalangaCJPejchalMKosofskyBE

2007

Prenatal exposure to cocaine alters the development of conditioned place-preference to cocaine in adult mice.

Pharmacol Biochem Behav

87

462

471

6. LidowMSSongZM

2001

Primates exposed to cocaine in utero display reduced density and number of cerebral cortical neurons.

J Comp Neurol

435

263

275

7. LidowMSSongZM

2001

Effect of cocaine on cell proliferation in the cerebral wall of monkey fetuses.

Cereb Cortex

11

545

551

8. HuSCheeranMCShengWSNiHTLokensgardJR

2006

Cocaine alters proliferation, migration, and differentiation of human fetal brain-derived neural precursor cells.

J Pharmacol Exp Ther

318

1280

1286

9. DeySSnowDM

2007

Cocaine exposure in vitro induces apoptosis in fetal locus coeruleus neurons through TNF-alpha-mediated induction of Bax and phosphorylated c-Jun NH(2)-terminal kinase.

J Neurochem

103

542

556

10. KosofskyBEHymanSE

2001

No time for complacency: The fetal brain on drugs.

J Comp Neurol

435

259

262

11. FrankDAAugustynMKnightWGPellTZuckermanB

2001

Growth, development, and behavior in early childhood following prenatal cocaine exposure: A systematic review.

JAMA

285

1613

1625