Chromatin Remodeling in Development and Disease: Focus on CHD7

1. VissersLE

van RavenswaaijCM

AdmiraalR

HurstJA

de VriesBB

2004 Mutations in a new member of the chromodomain gene family cause CHARGE syndrome. Nat Genet 36 955 957

2. ZentnerGE

LaymanWS

MartinDM

ScacheriPC

2010 Molecular and phenotypic aspects of CHD7 mutation in CHARGE syndrome. Am J Med Genet A 152A 674 686

3. BosmanEA

PennAC

AmbroseJC

KettleboroughR

StempleDL

2005 Multiple mutations in mouse Chd7 provide models for CHARGE syndrome. Hum Mol Genet 14 3463 3476

4. HurdEA

CapersPL

BlauwkampMN

AdamsME

RaphaelY

2007 Loss of Chd7 function in gene-trapped reporter mice is embryonic lethal and associated with severe defects in multiple developing tissues. Mamm Genome 18 94 104

5. SchnetzMP

BartelsCF

ShastriK

BalasubramanianD

ZentnerGE

2009 Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns. Genome Res 19 590 601

6. SchnetzMP

HandokoL

Akhtar-ZaidiB

BartelsCF

PereiraCF

2010 CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression. PLoS Genet 6(7) e1001023 doi:10.1371/journal.pgen.1001023

7. BajpaiR

ChenDA

Rada-IglesiasA

ZhangJ

XiongY

2010 CHD7 cooperates with PBAF to control multipotent neural crest formation. Nature 463 958 962

8. HoL

JothiR

RonanJL

CuiK

ZhaoK

2009 An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network. Proc Natl Acad Sci U S A 106 5187 5191

9. TakadaI

MiharaM

SuzawaM

OhtakeF

KobayashiS

2007 A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation. Nat Cell Biol 9 1273 1285

10. LaymanWS

McEwenDP

BeyerLA

LalaniSR

FernbachSD

2009 Defects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndrome. Hum Mol Genet 18 1909 1923

11. HoL

CrabtreeGR

2010 Chromatin remodelling during development. Nature 463 474 484

12. De SarioA

2009 Clinical and molecular overview of inherited disorders resulting from epigenomic dysregulation. Eur J Med Genet 52 363 372

13. BagchiA

PapazogluC

WuY

CapursoD

BrodtM

2007 CHD5 is a tumor suppressor at human 1p36. Cell 128 459 475

14. PeoplesRJ

CiscoMJ

KaplanP

FranckeU

1998 Identification of the WBSCR9 gene, encoding a novel transcriptional regulator, in the Williams-Beuren syndrome deletion at 7q11.23. Cytogenet Cell Genet 82 238 246