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The Community As the Patient in Malaria-Endemic Areas: Preempting Drug Resistance with Multiple First-Line Therapies


Maciej F.
Boni and colleagues propose deploying multiple first-line combination therapies against malaria within a community to delay drug-resistance evolution.


Vyšlo v časopise: The Community As the Patient in Malaria-Endemic Areas: Preempting Drug Resistance with Multiple First-Line Therapies. PLoS Med 13(3): e32767. doi:10.1371/journal.pmed.1001984
Kategorie: Policy Forum
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pmed.1001984

Souhrn

Maciej F.
Boni and colleagues propose deploying multiple first-line combination therapies against malaria within a community to delay drug-resistance evolution.


Zdroje

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6. A study by the tracking resistance to artemisinin collaboration (TRACII). 2015. https://clinicaltrials.gov/ct2/show/NCT02453308?term=NCT02453308&rank=1.

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14. Sutherland CJ, Babiker H, Mackinnon MJ, Ranford-Cartwright L, El Sayed BB. Rational deployment of antimalarial drugs in Africa: should first-line combination drugs be reserved for paediatric cases? Parasitology. 2011; 138:1459–1468. doi: 10.1017/S0031182011001144 21810298

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16. Sabot OJ, Mwita A, Cohen JM, Ipuge Y, Gordon M, Bishop D, et al. Piloting the global subsidy: the impact of subsidized artemisinin-based combination therapies distributed through private drug shops in rural Tanzania. PLoS ONE. 2009; 4:e6857. doi: 10.1371/journal.pone.0006857 19724644

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18. Ursing J, Kofoed P-E, Rodrigues A, Blessborn D, Thoft-Nielsen R, Björkman A, et al. Similar efficacy and tolerability of double-dose chloroquine and artemether-lumefantrine for treatment of Plasmodium falciparum infection in Guinea-Bissau: a randomized trial. J Infect Dis. 2011; 203:109–116. doi: 10.1093/infdis/jiq001 21148503

19. Yeka A, Kigozi R, Conrad MD, Lugemwa M, Okui P, Katureebe C, et al. Artesunate/amodiaquine versus artemether/lumefantrine for the treatment of uncomplicated malaria in Uganda: a randomized trial. J Infect Dis. 2015; e-pub ahead of print, doi: 10.1093/infdis/jiv551

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Interné lekárstvo

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