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PLOS Genetics - Číslo 6/2012

Research Article

32767

Selection-Driven Gene Loss in Bacteria

Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer

Parallel Evolution of Auditory Genes for Echolocation in Bats and Toothed Whales

Diverse CRISPRs Evolving in Human Microbiomes

The Rad4 ATR-Activation Domain Functions in G1/S Phase in a Chromatin-Dependent Manner

Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains

Uracil-Containing DNA in : Stability, Stage-Specific Accumulation, and Developmental Involvement

Fuzzy Tandem Repeats Containing p53 Response Elements May Define Species-Specific p53 Target Genes

Adaptive Introgression across Species Boundaries in Butterflies

G Protein Activation without a GEF in the Plant Kingdom

Synaptonemal Complex Components Persist at Centromeres and Are Required for Homologous Centromere Pairing in Mouse Spermatocytes

An Engineering Approach to Extending Lifespan in

Incompatibility and Competitive Exclusion of Genomic Segments between Sibling Species

Effects of Histone H3 Depletion on Nucleosome Occupancy and Position in

Patterns of Evolutionary Conservation of Essential Genes Correlate with Their Compensability

Interplay between Synaptonemal Complex, Homologous Recombination, and Centromeres during Mammalian Meiosis

Preferential Genome Targeting of the CBP Co-Activator by Rel and Smad Proteins in Early Embryos

A Mouse Model of Acrodermatitis Enteropathica: Loss of Intestine Zinc Transporter ZIP4 (Slc39a4) Disrupts the Stem Cell Niche and Intestine Integrity

Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2

Geographic Differences in Genetic Susceptibility to IgA Nephropathy: GWAS Replication Study and Geospatial Risk Analysis

Cohesin Proteins Promote Ribosomal RNA Production and Protein Translation in Yeast and Human Cells

TERRA Promotes Telomere Shortening through Exonuclease 1–Mediated Resection of Chromosome Ends

Stimulation of Host Immune Defenses by a Small Molecule Protects from Bacterial Infection

A Broad Requirement for TLS Polymerases η and κ, and Interacting Sumoylation and Nuclear Pore Proteins, in Lesion Bypass during Embryogenesis

Genome-Wide Identification of Ampicillin Resistance Determinants in

The CCR4-NOT Complex Is Implicated in the Viability of Aneuploid Yeasts

Gustatory Perception and Fat Body Energy Metabolism Are Jointly Affected by Vitellogenin and Juvenile Hormone in Honey Bees

Genetic Variants on Chromosome 1q41 Influence Ocular Axial Length and High Myopia

Is a Key Regulator of Pancreaticobiliary Ductal System Development

The NSL Complex Regulates Housekeeping Genes in

Attenuation of Notch and Hedgehog Signaling Is Required for Fate Specification in the Spinal Cord

Dual-Level Regulation of ACC Synthase Activity by MPK3/MPK6 Cascade and Its Downstream WRKY Transcription Factor during Ethylene Induction in Arabidopsis

Genome-Wide Functional Profiling Identifies Genes and Processes Important for Zinc-Limited Growth of

Base-Pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid Leukemia

MicroRNA93 Regulates Proliferation and Differentiation of Normal and Malignant Breast Stem Cells

Phylogenomic Analysis Reveals Dynamic Evolutionary History of the Drosophila Heterochromatin Protein 1 (HP1) Gene Family

The Mutation in Chickens Constitutes a Structural Rearrangement Causing Both Altered Comb Morphology and Defective Sperm Motility

Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases

Polymorphisms in the Mitochondrial Ribosome Recycling Factor Compromise Cell Respiratory Function and Increase Atorvastatin Toxicity

Gene Expression Profiles in Parkinson Disease Prefrontal Cortex Implicate and Genes under Its Transcriptional Regulation

Global Regulatory Functions of the Endoribonuclease III in Gene Expression

Extensive Evolutionary Changes in Regulatory Element Activity during Human Origins Are Associated with Altered Gene Expression and Positive Selection

The Regulatory Network of Natural Competence and Transformation of

Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants

Quantifying the Adaptive Potential of an Antibiotic Resistance Enzyme

Divergence of the Yeast Transcription Factor Affects Sulfite Resistance

The Histone Demethylase Jhdm1a Regulates Hepatic Gluconeogenesis

RNA Methylation by the MIS Complex Regulates a Cell Fate Decision in Yeast

Rare Copy Number Variants Observed in Hereditary Breast Cancer Cases Disrupt Genes in Estrogen Signaling and Tumor Suppression Network

Genome-Wide Location Analysis Reveals Distinct Transcriptional Circuitry by Paralogous Regulators Foxa1 and Foxa2

A Mutation Links a Canine Progressive Early-Onset Cerebellar Ataxia to the Endoplasmic Reticulum–Associated Protein Degradation (ERAD) Machinery

The Mechanism for RNA Recognition by ANTAR Regulators of Gene Expression

Limits to the Rate of Adaptive Substitution in Sexual Populations

Perspective

32767

Rumors of Its Disassembly Have Been Greatly Exaggerated: The Secret Life of the Synaptonemal Complex at the Centromeres

Mimetic Butterflies Introgress to Impress

Tipping the Balance in the Powerhouse of the Cell to “Protect” Colorectal Cancer

Found: The Elusive ANTAR Transcription Antiterminator

PLOS Genetics

2012 Číslo 6

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