The Role of Procalcitonin in the Differencial Diagnosis of Fever in Patiens with Multiple Myeloma

Česká verzia

Authors: K. Machálková; V. Maisnar
Authors place of work: II. interní klinika, Oddělení klinické hematologie, LF UK a FN Hradec Králové
Published in the journal: Klin Onkol 2011; 24(4): 298-301
Category: Kazuistiky

Summary

Fever and elevated C-reactive protein are frequently found in hematooncological patients. It is sometimes difficult to distinguish between infectious fever and drug-related or tumour-associated fever. Tumour-related fever is not very common in multiple myeloma (unlike malignant lymphomas). C-reactive protein (CRP) is usually elevated simultaneously with fever and so it cannot be used in differential diagnosis of febrile states. There is another marker that provides information about the origins of the fever – procalcitonin. We present cases of three patients that illustrate the significance of procalcitonin in patients with multiple myeloma.

Key words:
multiple myeloma – procalcitonin – fever – C-reactive protein

Zdroje

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