Fibrobronchoscopy, Bronchoalveolar Lavage and Transbronchial Biopsy in the Diagnosis ofDiseases of the Pulmonary Interstitium in Children
Fibrobronchoskopia, bronchoalveolárna laváž a transbronchiálnabiopsia v diagnostike chorôb pľúcneho interstícia detí
Autori popisujú metodiku fibrobronchoskopie, bronchoalveolárnej laváže a transbronchiálnej biopsie. Súzhodnotené výsledky z transbronchiálnych biopsií u 97 detí, ktorým bola táto urobená pri podozrení na poškodeniepľúcneho interstícia.Pľúcny parenchým bol biopsiou získaný u 62 detí (63,9 %). Z toho u 36 detí bola potvrdená niektorá formaidiopatickej intersticiálnej pľúcnej fibrózy, u 6 detí sarkoidóza (overená cytologicky z perbronchiálnej punkciea 1krát histologicky), 1krát bola histologicky verifikovaná exogénna alergická alveolitída a u 4 detí overenáhemosideróza (2krát siderofágy v bronchoalveolárnej laváži a 2krát aj histologicky).U histologicky potvrdených nálezov hodnotia autori bronchoskopické nálezy, uvádzajú výsledky z vyšetreníbronchoalveolárnej laváže (včítane hodnotenia T-lymfocytov - CD3 a CD4 a CD8 subpopulácií). Uzatvárajú, žeBAL má t.č. pri IPCH detí len informatívny charakter, i keď korelácia medzi histologickým nálezom z TBBa cytologickým obrazom z BAL je relatívne vysoká. TBB je jednou z možností ako verifikovať poškodeniepľúcneho interstícia.Podľa názoru autorov sú kompletné údaje o TBB a BAL u detí s intersticiálnymi pľúcnymi chorobami sozhodnotením endoskopického obrazu, BAL a histologických nálezov prvýkrát publikované.
Klíčová slova:
intersticiálne pľúcne choroby u detí, diagnostika, fibrobronchoskopia, bronchoalveolárna
Authors:
M. Šelest 1; L. Doležel 2; V. Herout 3; I. Chudý 4; I. Schwendt 5
Authors‘ workplace:
Dětská klinika FN, Plzeň
1
Published in:
Čes-slov Pediat 2000; (4): 230-235.
Category:
Overview
The authors describe the method of fibrobronchoscopy, bronchoalveolar lavage and transbronchial biopsy.They evaluate the results of transbronchial biopsies in 97 children where damage of the pulmonary interstitiumwas suspected.The pulmonary parenchyma was obtained by biopsy from 62 children (63.9%). Of these in 36 children someform of idiopathic interstitial pulmonary fibrosis was confirmed, in 6 children sarcoidosis (confirmed by cytologicalexamination of perbronchial puncture and in one case by histological examination). In one instance exogenousallergic alveolitis was confirmed by histological examination and in four children haemosiderosis (2x siderophagesin the bronchoalveolar lavage and 2x also by histological examination).In histologically confirmed findings the authors evaluate the bronchoscopic findings, they present the resultsof bronchoalveolar lavage (incl. evaluation of T lymphocytes - CD3 and CD4 a CD8 sub-populations). Theyconclude that BAL serves in IPCH in children for preliminary information although the correlation between thehistological findings of TBB and cytological finding from BAL is relatively close. TBB is one of the possible wayshow to verify damage of the pulmonary interstitium.In the authors’ opinion complete data on TBB and BAL in children with interstitial lung disease with evaluationof the endoscopic picture, BAL and histological findings were published for the first time.
Key words:
interstitial lung diseases in children, diagnosis, fibrobronchoscopy, bronchoalveolar lavage,
Labels
Neonatology Paediatrics General practitioner for children and adolescentsArticle was published in
Czech-Slovak Pediatrics
2000 Issue 4
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