Amyotrophic Lateral Sclerosis, A Motoneuron Disorder
Amyotrophic Lateral Sclerosis, A Motoneuron Disorder
The term „motoneuron disorder“ has been used for a degenerative disease of the motor system. In its etiology,the role is probably played by more factors out of which excitotoxic theory has been nowadays consideredas the most significant one. Besides amyotrophic lateral sclerosis, this group also involves progressivebulbar paralysis, progressive muscular atrophy, primary lateral sclerosis, brachial amyotrophic diplegia,and monomelic muscular atrophy. Both clinical and electrophysiological diagnostic criteria have been developedfor ALS, they enable the decision for early therapy as well as inclusion in clinical trials. In addition toriluzole treatment, individual symptomatic therapy is needed.
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Autoři:
M. Nouza
Působiště autorů:
Neurologická klinika IPVZ a FTN Praha
Vyšlo v časopise:
Prakt. Lék. 2003; (8): 408-417
Kategorie:
Články
Souhrn
The term „motoneuron disorder“ has been used for a degenerative disease of the motor system. In its etiology,the role is probably played by more factors out of which excitotoxic theory has been nowadays consideredas the most significant one. Besides amyotrophic lateral sclerosis, this group also involves progressivebulbar paralysis, progressive muscular atrophy, primary lateral sclerosis, brachial amyotrophic diplegia,and monomelic muscular atrophy. Both clinical and electrophysiological diagnostic criteria have been developedfor ALS, they enable the decision for early therapy as well as inclusion in clinical trials. In addition toriluzole treatment, individual symptomatic therapy is needed.
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Štítky
Praktické lekárstvo pre deti a dorast Praktické lekárstvo pre dospelýchČlánok vyšiel v časopise
Praktický lékař
2003 Číslo 8
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