A Nested Case–Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)

English version České info

Gunter and colleagues analyse a large European dataset to determine how body size and metabolic profile associates with the risk of developing colorectal cancer.

Vyšlo v časopise: A Nested Case–Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). PLoS Med 13(4): e32767. doi:10.1371/journal.pmed.1001988
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pmed.1001988

Souhrn

Gunter and colleagues analyse a large European dataset to determine how body size and metabolic profile associates with the risk of developing colorectal cancer.

Zdroje

1. Larsson SC, Wolk A (2007) Obesity and colon and rectal cancer risk: a meta-analysis of prospective studies. Am J Clin Nutr 86 : 556–565. 17823417

2. Moghaddam AA, Woodward M, Huxley R (2007) Obesity and risk of colorectal cancer: a meta-analysis of 31 studies with 70,000 events. Cancer Epidemiol Biomarkers Prev 16 : 2533–2547. 18086756

3. Vazquez G, Duval S, Jacobs DR, Silventoinen K (2007) Comparison of body mass index, waist circumference, and waist/hip ratio in predicting incident diabetes: a meta-analysis. Epidemiol Rev 29 : 115–128. 17494056

4. Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M (2008) Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 371 : 569–578. doi: 10.1016/S0140-6736(08)60269-X 18280327

5. Pischon T, Lahmann PH, Boeing H, Friedenreich C, Norat T, Tjonneland A, et al. (2006) Body size and risk of colon and rectal cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC). J Natl Cancer Inst 98 : 920–931. 16818856

6. Giovannucci E (2007) Metabolic syndrome, hyperinsulinemia, and colon cancer: a review. Am J Clin Nutr 86 : 836S–842S.

7. Gunter MJ, Hoover DR, Yu H, Wassertheil-Smoller S, Rohan TE, et al. (2008) Insulin, insulin-like growth factor-I, endogenous estradiol, and risk of colorectal cancer in postmenopausal women. Cancer Res 68 : 329–337. doi: 10.1158/0008-5472.CAN-07-2946 18172327

8. Schoen RE, Tangen CM, Kuller LH, Burke GL, Cushman M, et al. (1999) Increased blood glucose and insulin, body size, and incident colorectal cancer. J Natl Cancer Inst 91 : 1147–1154. 10393723

9. Bonser AM, Garcia-Webb P, Harrison LC (1984) C-peptide measurement: methods and clinical utility. Crit Rev Clin Lab Sci 19 : 297–352. doi: 10.3109/10408368409165766 6373142

10. Kaaks R, Toniolo P, Akhmedkhanov A, Lukanova A, Biessy C, et al. (2000) Serum C-peptide, insulin-like growth factor (IGF)-I, IGF-binding proteins, and colorectal cancer risk in women. J Natl Cancer Inst 92 : 1592–1600. 11018095

11. Jenab M, Riboli E, Cleveland RJ, Norat T, Rinaldi S, et al. (2007) Serum C-peptide, IGFBP-1 and IGFBP-2 and risk of colon and rectal cancers in the European Prospective Investigation into Cancer and Nutrition. Int J Cancer 121 : 368–376. doi: 10.1002/ijc.22697 17372899

12. Ma J, Giovannucci E, Pollak M, Leavitt A, Tao Y, et al. (2004) A prospective study of plasma C-peptide and colorectal cancer risk in men. J Natl Cancer Inst 96 : 546–553. 15069117

13. Gunter MJ, Xie X, Xue X, Kabat GC, Rohan TE, et al. (2015) Breast cancer risk in metabolically healthy but overweight postmenopausal women. Cancer Res 75 : 270–274. doi: 10.1158/0008-5472.CAN-14-2317 25593034

14. Ogorodnikova AD, Kim M, McGinn AP, Muntner P, Khan U, et al. (2012) Incident cardiovascular disease events in metabolically benign obese individuals. Obesity 20 : 651–659. doi: 10.1038/oby.2011.243 21799477

15. Meigs JB, Wilson PWF, Fox CS, Vasan RS, Nathan DM, et al. (2006) Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease. J Clin Endocrinol Metab 91 : 2906–2912. 16735483

16. Bo S, Musso G, Gambino R, Villois P, Gentile L, et al. (2012) Prognostic implications for insulin-sensitive and insulin-resistant normal-weight and obese individuals from a population-based cohort. Am J Clin Nutr 96 : 962–969. doi: 10.3945/ajcn.112.040006 23034958

17. Riboli E, Kaaks R (1997) The EPIC Project: rationale and study design. European Prospective Investigation into Cancer and Nutrition. Int J Epidemiol 26: S6. 9126529

18. Riboli E, Hunt KJ, Slimani N, Ferrari P, Norat T, et al. (2002) European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection. Public Health Nutr 5 : 1113–1124. 12639222

19. Rinaldi S, Rohrmann S, Jenab M, Biessy C, Sieri S, Palli D, et al. (2008) Glycosylated hemoglobin and risk of colorectal cancer in men and women, the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiol Biomarkers Prev 17 : 3108–3115. doi: 10.1158/1055-9965.EPI-08-0495 18990751

20. Alberti KGM, Zimmet P, Shaw J (2005) The metabolic syndrome—a new worldwide definition. Lancet 366 : 1059–1062. 16182882

21. Dvorak RV, DeNino WF, Ades PA, Poehlman ET (1999) Phenotypic characteristics associated with insulin resistance in metabolically obese but normal-weight young women. Diabetes 48 : 2210–2214. 10535456

22. Hyun YJ, Koh SJ, Chae JS, Kim JY, Kim OY, et al. (2008) Atherogenecity of LDL and unfavorable adipokine profile in metabolically obese, normal-weight woman. Obesity 16 : 784–789. doi: 10.1038/oby.2007.127 18239579

23. De Lorenzo A, Del Gobbo V, Premrov MG, Bigioni M, Galvano F, et al. (2007) Normal-weight obese syndrome: early inflammation? Am J Clin Nutr 85 : 40–45. 17209175

24. Yun KE, Chang Y, Jung HS, Kim CW, Kwon MJ, et al. (2013) Impact of body mass index on the risk of colorectal adenoma in a metabolically healthy population. Cancer Res 73 : 4020–4027. doi: 10.1158/0008-5472.CAN-12-3477 23687341

25. Aleksandrova K, Boeing H, Jenab M, Bas Bueno-de-Mesquita H, Jansen E, et al. (2011) Metabolic syndrome and risks of colon and rectal cancer: the European Prospective Investigation into Cancer and Nutrition Study. Cancer Prev Res 4 : 1873–1883.

26. Aleksandrova K, Nimptsch KF, Pischon T (2013) Influence of obesity and related metabolic alterations on colorectal cancer risk. Curr Nutr Rep 2 : 1–9. 23396857

27. Wei EK, Ma J, Pollak MN, Rifai N, Fuchs CS, et al. (2005) A prospective study of C-peptide, insulin-like growth factor-I, insulin-like growth factor binding protein-1, and the risk of colorectal cancer in women. Cancer Epidemiol Biomarkers Prev 14 : 850–855. 15824155

28. Kitahara CM, Berndt SI, de Gonzalez AB, Coleman HG, Schoen RE, et al. (2013) Prospective investigation of body mass index, colorectal adenoma, and colorectal cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. J Clin Oncol 31 : 2450–2459. doi: 10.1200/JCO.2012.48.4691 23715565