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Kyasanur forest disease: A brief overview and relevance to public health in the Czech Republic


Authors: M. Špačková 1 ;  H. Orlíková 1,2 ;  J. Kynčl 1,2 ;  K. Kybicová 3 ;  J. Košťálová 1
Authors place of work: Oddělení epidemiologie infekčních nemocí, Centrum epidemiologie a mikrobiologie, Státní zdravotní ústav, Praha 1;  Ústav epidemiologie a biostatistiky 3. LF UK, Praha 2;  Národní referenční laboratoř pro lymeskou borreliózu, Centrum epidemiologie a mikrobiologie, Státní zdravotní ústav, Praha 3
Published in the journal: Epidemiol. Mikrobiol. Imunol. 75, 2026, č. 3, s. 127-130
Category: Krátké sdělení
doi: https://doi.org/10.61568/emi/11-6760/20260624/143938

Summary

Kyasanur forest disease is a tick-borne haemorrhagic disease endemic to southern India. The cases have recently been on the rise in India, and the area of occurrence is expanding. This is primarily due to climate change, deforestation, and increased human contact with forest ecosystems. The symptoms include fever, myalgia, haemorrhagic manifestations, and neurological complications. The case-fatality rate ranges from 3% to 10%. Kyasanur forest disease may be underdiagnosed, given its possible subclinical course. In India, an inactivated vaccine was available until 2022 but was withdrawn due to limited efficacy and short-term protection. Education and protection against ticks remain the primary means of prevention. Kyasanur forest disease has not yet been reported in the Czech Republic; however, we may encounter imported cases in the future following travel to endemic areas. The disease is becoming a significant emerging zoonosis, underscoring the need for a One Health approach and strengthened surveillance of arboviruses in Central Europe as well.

Keywords:

surveillance – Zoonoses – India – Climate change – Kyasanur Forest Disease – One Health – flavivirus – tick-borne diseases


Zdroje

1. Pandey N, Singh SK. Kyasanur Forest disease: an emerging arboviral threat. Lancet Infect Dis., 2026;26(5):e228–e239. DOI: 10.1016/S1473-3099(25)00589-4.

2. Bohra B, Srivastava KS, Raj A, et al. Kyasanur Forest Disease Virus: Epidemiological Insights, Pathogenesis, Therapeutic Strategies, and Advances in Vaccines and Diagnostics. Viruses, 2025;17(8):1022. DOI: 10.3390/v17081022.

3. Chunduru K, Saravu K. Kyasanur Forest Disease: A Review on the Emerging Infectious Disease. J Clin Infect Dis Soc., 2023;1(1):5 –⁠ 11. DOI: 10.4103/CIDS.CIDS_13_23

4. Mourya DT, Yadav PD, Patil DY, et al. Experiences of Indian Council of Medical Research with tick-borne zoonotic infections: Kyasanur Forest disease & Crimean-Congo haemorrhagic fever in India with One Health focus. Indian J Med Res., 2021;153(3):339 –⁠ 347. DOI: 10.4103/ijmr.IJMR_532_21.

5. Vedachalam SK, Rajput BL, Choudhary S, et al. Kyasanur Forest Disease: An Epidemiological Investigation and Case-Control Study in Shivamogga, Karnataka, India-2022. Int J Public Health, 2024;69 : 1606715. DOI: 10.3389/ijph.2024.1606715.

6. Yadav PD, Sahay RR, Mourya DT. Detection of Kyasanur forest disease in newer areas of Sindhudurg district of Maharashtra State. Indian J Med Res., 2018;148(4):453–455. DOI: 10.4103/ijmr. IJMR_1292_17.

7. Walsh MG, Mor SM, Maity H, et al. Forest loss shapes the landscape suitability of Kyasanur Forest disease in the biodiversity hotspots of the Western Ghats, India. Int J Epidemiol., 2019;48(6):1804–1814. DOI: 10.1093/ije/dyz232.

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9. Yadav PD, Patil S, Jadhav SM, et al. Phylogeography of Kyasanur Forest Disease virus in India (1957–2017) reveals evolution and spread in the Western Ghats region. Sci Rep., 2020;10(1):1966. DOI: 10.1038/s41598-020-58242-w.

10. Kaushal H, Kartaskar RS, Chiplunkar T, et al. Cellular Immune Responses Against γ-Inactivated Antigen in the Recovered Cases of Kyasanur Forest Disease. Viral Immunol., 2024;37(2):101–106. DOI: 10.1089/vim.2023.0107.

Štítky
Hygiena a epidemiológia Infekčné lekárstvo Mikrobiológia

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Epidemiologie, mikrobiologie, imunologie

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