Chlamydia and Atherosclerosis
Chlamydie a ateroskleróza
Přehled o potenciálním vztahu Chlamydia pneumoniae (C.p.) ke vzniku aterosklerózy cév.Článek je uveden poukazem na nejnovější taxonomická kritéria, podle nichž se pro druh C.p.zavádí název Chlamydophila pneumoniae (podle příslušnosti do nového rodu Chlamydophila).Autor v článku používá dosud běžně používaných názvů. Průkaz C.p. v aterosklerotických lézíchbyl proveden s pomocí různých metod (kultivace, elektronová mikroskopie, imunohistochemie,polymerázová řetězová reakce atd.). Sérové protilátky proti antigenům C.p. (zvláště protilipopolysacharidu) jsou signifikantně častější u osob s aterosklerózou a jejími cévními komplikacemi.Exaktní důkaz o kauzálním vztahu C.p. pro vznik aterosklerózy však ještě nebyl podán.Přesto zůstává chronická infekce C.p. významným rizikovým faktorem vzniku kardiovaskulárníchkomplikací aterosklerózy.
Klíčová slova:
chlamydie - ateroskleróza - cévní komplikace.
Authors:
L. Pospíšil
Authors‘ workplace:
Výzkumný ústav veterinárního lékařství Brno, ředitel doc. MVDr. M. Toman, CSc.
Published in:
Prakt. Lék. 2003; (2): 59-61
Category:
Overview
A review of published data on the possible role of Chlamydia pneumoniae (C.p.) in the aetiologyof atherosclerosis is presented. Updated taxonomic criteria have introduced the new nameChlamydophila pneumoniae derived from the name of the new genus Chlamydophila. In hisarticle, the author adheres to the currently used nomenclature. The presence of chlamydiae inatherosclerotic lesions has been demonstrated by several methods, such as cultivation, electronmicroscopy, immunohistochemical tests, or polymerase chain reaction. The prevalence of bloodserum antibodies to C.p. antigens (particularly lipopolysaccharides) in patients suffering fromatherosclerosis and vascular complications associated therewith is significantly higher than inthe normal population. Although no exact proof of a causative role of C.p. in the developmentof atherosclerosis has been furnished so far, chronic C.p. infection must be regarded asa significant risk factor influencing the development of cardiovascular atherosclerotic complications.
Key words:
Chlamydia - atherosclerosis - vascular complications.
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
2003 Issue 2
- Metamizole at a Glance and in Practice – Effective Non-Opioid Analgesic for All Ages
- Metamizole in perioperative treatment in children under 14 years – results of a questionnaire survey from practice
- Hope Awakens with Early Diagnosis of Parkinson's Disease Based on Skin Odor
- Advances in the Treatment of Myasthenia Gravis on the Horizon
- The Importance of Limosilactobacillus reuteri in Administration to Diabetics with Gingivitis
-
All articles in this issue
- Congestive Heart Failure: Neuroendocrine and Inflammatory Response
- Brain Natriuretic Peptide (BNP)
- Nutrition of Cancer Patrients
- Symptoms of Psychiatric Disorders and Problems with Their Assessment.Part II. Couvade Syndrome
- Spondylodiscitis: Known - Unknown?
- Exudative Pericarditis as a Serious Complication of Tumourous Disease
- Metastasis of Laryngeal Cancer into the Penis
- Laboratory Diagnostic of Rubella
- Immunosuppressive Drugs as a Possible Cause of Psychiatric Complications in Patients after Organ Transplantation
- Erectile Dysfunction as the First Symptoms of Cardiovascular Disease
- Disabled People - Position Statement on Bioethics and Human Rights (or How to Teach Medical Ethics)
- Chlamydia and Atherosclerosis
- General Practitioner
- Journal archive
- Current issue
- About the journal
Most read in this issue
- Congestive Heart Failure: Neuroendocrine and Inflammatory Response
- Spondylodiscitis: Known - Unknown?
- Chlamydia and Atherosclerosis
- Brain Natriuretic Peptide (BNP)