Facility-Based Delivery during the Ebola Virus Disease Epidemic in Rural Liberia: Analysis from a Cross-Sectional, Population-Based Household Survey

John Kraemer and colleagues estimate changes in facility-based delivery during the Ebola virus disease epidemic in rural Liberia using cross-sectional data from a population-based household survey.

Vyšlo v časopise: Facility-Based Delivery during the Ebola Virus Disease Epidemic in Rural Liberia: Analysis from a Cross-Sectional, Population-Based Household Survey. PLoS Med 13(8): e32767. doi:10.1371/journal.pmed.1002096
Kategorie: Research Article
prolekare.web.journal.doi_sk: 10.1371/journal.pmed.1002096


John Kraemer and colleagues estimate changes in facility-based delivery during the Ebola virus disease epidemic in rural Liberia using cross-sectional data from a population-based household survey.


1. World Health Organization. Ebola Situation Report—16 March 2016. 2016; Available at: http://apps.who.int/ebola/current-situation/ebola-situation-report-16-march-2016. Accessed March 20, 2016.

2. Evans DK, Goldstein M, Popova A. Health-care worker mortality and the legacy of the Ebola epidemic. The Lancet Global Health 2015 2015/07.

3. World Health Organization. Ebola Situation Report—5 August 2015. 2015. http://apps.who.int/ebola/current-situation/ebola-situation-report-5-august-2015. Accessed August 6, 2015.

4. Abramowitz SA, McLean KE, McKune SL, Bardosh KL, Fallah M, Monger J, et al. Community-centered responses to Ebola in urban Liberia: the view from below. PLoS Negl Trop Dis 2015 Apr 9;9(4):e0003706. doi: 10.1371/journal.pntd.0003706 25856072

5. Hamel MJ, Slutsker L. Ebola: the hidden toll. Lancet Infect Dis 2015 Apr 23.

6. WHO Ebola Response Team. Ebola virus disease in West Africa—the first 9 months of the epidemic and forward projections. N Engl J Med 2014 Oct 16;371(16):1481–1495. doi: 10.1056/NEJMoa1411100 25244186

7. Iyengar P, Kerber K, Howe CJ, Dahn B. Services for mothers and newborns during the ebola outbreak in liberia: the need for improvement in emergencies. PLoS Curr 2015 Apr 16;7:doi: 10.1371/currents.outbreaks.4ba318308719ac86fbef91f8e56cb66f

8. Helleringer S, Noymer A. Assessing the direct effects of the ebola outbreak on life expectancy in liberia, sierra leone and Guinea. PLoS Curr 2015 Feb 19;7:doi: 10.1371/currents.outbreaks.01a99f8342b42a58d806d7d1749574ea

9. De Roo A, Ado B, Rose B, Guimard Y, Fonck K, Colebunders R. Survey among survivors of the 1995 Ebola epidemic in Kikwit, Democratic Republic of Congo: their feelings and experiences. Trop Med Int Health 1998 Nov;3(11):883–885. 9855400

10. Takahashi S, Metcalf CJ, Ferrari MJ, Moss WJ, Truelove SA, Tatem AJ, et al. Reduced vaccination and the risk of measles and other childhood infections post-Ebola. Science 2015 Mar 13;347(6227):1240–1242. doi: 10.1126/science.aaa3438 25766232

11. Walker PG, White MT, Griffin JT, Reynolds A, Ferguson NM, Ghani AC. Malaria morbidity and mortality in Ebola-affected countries caused by decreased health-care capacity, and the potential effect of mitigation strategies: a modelling analysis. Lancet Infect Dis 2015 Apr 23.

12. Delamou A, Hammonds RM, Caluwaerts S, Utz B, Delvaux T. Ebola in Africa: beyond epidemics, reproductive health in crisis. Lancet 2014 Dec 13;384(9960):2105-6736(14)62364-3.

13. Bolkan HA, Bash-Taqi DA, Samai M, Gerdin M, von Schreeb J. Ebola and indirect effects on health service function in sierra leone. PLoS Curr 2014 Dec 19;6:doi: 10.1371/currents.outbreaks.0307d588df619f9c9447f8ead5b72b2d

14. Ndawinz JD, Cisse M, Diallo MS, Sidibe CT, D'Ortenzio E. Prevention of HIV spread during the Ebola outbreak in Guinea. Lancet 2015 Apr 11;385(9976):1393-6736(15)60713-9. doi: 10.1016/S0140-6736(15)60713-9 25890415

15. Tattevin P, Baysah MK, Raguin G, Toomey J, Chapplain JM, Taylor ME, et al. Retention in care for HIV-infected patients in the eye of the Ebola storm: lessons from Monrovia, Liberia. AIDS 2015 Mar 27;29(6):N1–2. doi: 10.1097/QAD.0000000000000614 25849843

16. Loubet P, Mabileau G, Baysah M, Nuta C, Taylor M, Jusu H, et al. Likely effect of the 2014 Ebola epidemic on HIV care in Monrovia, Liberia. AIDS 2015;Publish Ahead of Print.

17. Leuenberger D, Hebelamou J, Strahm S, De Rekeneire N, Balestre E, Wandeler G, et al. Impact of the ebola epidemic on general and HIV care in Macenta, forest guinea, 2014. AIDS 2015;Publish Ahead of Print.

18. Plucinski MM, Guilavogui T, Sidikiba S, Diakite N, Diakite S, Dioubate M, et al. Effect of the Ebola-virus-disease epidemic on malaria case management in Guinea, 2014: a cross-sectional survey of health facilities. Lancet Infect Dis 2015 Jun 23.

19. Barden-O'Fallon J, Barry MA, Brodish P, Hazerjian J. Rapid Assessment of Ebola-Related Implications for Reproductive, Maternal, Newborn and Child Health Service Delivery and Utilization in Guinea. PLoS Curr 2015 Aug 4;7:doi: 10.1371/currents.outbreaks.0b0ba06009dd091bc39ddb3c6d7b0826

20. Lori JR, Rominski SD, Perosky JE, Munro ML, Williams G, Bell SA, et al. A case series study on the effect of Ebola on facility-based deliveries in rural Liberia. BMC Pregnancy Childbirth 2015 Oct 12;15:254-015-0694-x.

21. Brolin Ribacke KJ, van Duinen AJ, Nordenstedt H, Hoijer J, Molnes R, Froseth TW, et al. The Impact of the West Africa Ebola Outbreak on Obstetric Health Care in Sierra Leone. PLoS ONE 2016 Feb 24;11(2):e0150080. doi: 10.1371/journal.pone.0150080 26910462

22. Parpia AS, Ndeffo-Mbah ML, Wenzel NS, Galvani AP. Effects of Response to 2014–2015 Ebola Outbreak on Deaths from Malaria, HIV/AIDS, and Tuberculosis, West Africa. Emerg Infect Dis 2016 Mar;22(3):433–441. doi: 10.3201/eid2203.150977 26886846

23. Kruk ME, Myers M, Varpilah ST, Dahn BT. What is a resilient health system? Lessons from Ebola. Lancet 2015 May 9;385(9980):1910–1912. doi: 10.1016/S0140-6736(15)60755-3 25987159

24. Siedner MJ, Gostin LO, Cranmer HH, Kraemer JD. Strengthening the Detection of and Early Response to Public Health Emergencies: Lessons from the West African Ebola Epidemic. PLoS Med 2015;12(3):e1001804. doi: 10.1371/journal.pmed.1001804 25803303

25. Gostin LO, Friedman EA. A retrospective and prospective analysis of the west African Ebola virus disease epidemic: robust national health systems at the foundation and an empowered WHO at the apex. Lancet 2015 May 9;385(9980):1902–1909. doi: 10.1016/S0140-6736(15)60644-4 25987158

26. Heymann DL, Chen L, Takemi K, Fidler DP, Tappero JW, Thomas MJ, et al. Global health security: the wider lessons from the west African Ebola virus disease epidemic. Lancet 2015 May 9;385(9980):1884–1901. doi: 10.1016/S0140-6736(15)60858-3 25987157

27. Liberia Institute of Statistics and Geo-Information Services (Monrovia). Liberia Demographic and Health Survey 2013. Liberia Institute of Statistics and Geo-Information Services; 2014.

28. Liberia Institute of Statistics and Geo-Information Services (Monrovia). Liberia Demographic and Health Survey 2007. Liberia Institute of Statistics and Geo-Information Services; 2008.

29. Campbell OM, Graham WJ, Lancet Maternal Survival Series steering group. Strategies for reducing maternal mortality: getting on with what works. Lancet 2006 Oct 7;368(9543):1284–1299. 17027735

30. Moyer CA, Mustafa A. Drivers and deterrents of facility delivery in sub-Saharan Africa: a systematic review. Reprod Health 2013 Aug 20;10:40-4755-10-40.

31. Moyer CA, Adanu RM, Engmann CM. The relationship between facility-based delivery and maternal and neonatal mortality in Sub-Saharan Africa. Int J Gynaecol Obstet 2013 Sep;122(3):263–265. doi: 10.1016/j.ijgo.2013.04.010 23809657

32. Darmstadt GL, Bhutta ZA, Cousens S, Adam T, Walker N, de Bernis L, et al. Evidence-based, cost-effective interventions: how many newborn babies can we save? Lancet 2005 Mar 12–18;365(9463):977–988. 15767001

33. Koblinsky M, Matthews Z, Hussein J, Mavalankar D, Mridha MK, Anwar I, et al. Going to scale with professional skilled care. Lancet 2006 Oct 14;368(9544):1377–1386. 17046470

34. Gabrysch S, Campbell OM. Still too far to walk: literature review of the determinants of delivery service use. BMC Pregnancy Childbirth 2009 Aug 11;9:34-2393-9-34.

35. Wanjira C, Mwangi M, Mathenge E, Mbugua G, Ng'ang'a Z. Delivery practices and associated factors among mothers seeking child welfare services in selected health facilities in Nyandarua South District, Kenya. BMC Public Health 2011 May 21;11:360-2458-11-360.

36. Kerber KJ, de Graft-Johnson JE, Bhutta ZA, Okong P, Starrs A, Lawn JE. Continuum of care for maternal, newborn, and child health: from slogan to service delivery. Lancet 2007 Oct 13;370(9595):1358–1369. 17933651

37. Liberia Institute of Statistics and Geo-Information Services. 2008 National Population and Housing Census: Final Results. 2009.

38. Liberia Ministry of Health and Social Welfare. Liberia Ebola Daily Sitrep no. 350 for 30th April 2015. 2015.

39. Summers A, Nyenswah TG, Montgomery JM, Neatherlin J, Tappero JW, T N, et al. Challenges in responding to the ebola epidemic—four rural counties, Liberia, August-November 2014. MMWR Morb Mortal Wkly Rep 2014 Dec 19;63(50):1202–1204. 25522089

40. Hagan JE, Smith W, Pillai SK, Yeoman K, Gupta S, Neatherlin J, et al. Implementation of Ebola case-finding using a village chieftaincy taskforce in a remote outbreak—Liberia, 2014. MMWR Morb Mortal Wkly Rep 2015 Feb 27;64(7):183–185. 25719680

41. Kateh F, Nagbe T, Kieta A, Barskey A, Gasasira AN, Driscoll A, et al. Rapid response to Ebola outbreaks in remote areas—Liberia, July-November 2014. MMWR Morb Mortal Wkly Rep 2015 Feb 27;64(7):188–192. 25719682

42. ICF International. Sampling and Household Listing Manual: Demographic and Health Surveys Methodology. 2012 September 2012.

43. Turner AG. Sampling Strategies. Expert Group Meeting to Review the Draft Handbook on Designing of Household Sample Surveys 2003 November 3, 2003;ESA/STAT/AC.93/2.

44. United Nations. Designing household survey samples: practical guidelines. 2008;Series F, No. 98.

45. Kenny A, Basu G, Ballard M, Griffiths T, Kentoffio K, Niyonzima JB, et al. Remoteness and maternal and child health service utilization in rural Liberia: A population-based survey. J Glob Health 2015 Dec;5(2):020401. doi: 10.7189/jogh.05.020401 26207180

46. Milligan P, Njie A, Bennett S. Comparison of two cluster sampling methods for health surveys in developing countries. Int J Epidemiol 2004 Jun;33(3):469–476. 15020569

47. ICF Macro. Training Field Staff for DHS Surveys. 2009.

48. Williams WCL. Ebola Deaths Turn Redemption Hospital into Ghost Town. 2014. http://frontpageafricaonline.com/index.php/health-sci/1987-ebola-deaths-turn-liberia-s-redemption-hospital-into-ghost-town. Accessed April 30, 2015, 2015.

49. Front Page Africa. Deadly Ebola Bounces Back in Liberia—10 Unconfirmed Deaths. 2014. http://allafrica.com/stories/201406160729.html. Accessed April 30, 2015.

50. Gbelewala K. Report—One Dies of Ebola in Voinjama. 2014. http://allafrica.com/stories/201406190955.html. Accessed April 30, 2015.

51. StarAfrica. Liberia: Fresh Ebola Outbreak in Monrovia. 2014; Available at: http://en.starafrica.com/news/liberia-fresh-ebola-outbreak-in-monrovia.html. Accessed April 30, 2015.

52. Reuters. Sierra Leone Shuts Borders, Closes Schools to Fight Ebola. 2014. http://www.nytimes.com/reuters/2014/06/11/world/africa/11reuters-health-ebola-leone.html. Accessed April 30, 2015.

53. Press Associated. Doctors Without Borders: Ebola 'Out of Control'. 2014. http://www.nytimes.com/aponline/2014/06/20/world/africa/ap-af-west-africa-ebola.html. Accessed April 30, 2015.

54. Press Associated. Liberian Official: 7 More Deaths Linked to Ebola. 2014. http://www.nytimes.com/aponline/2014/06/17/world/africa/ap-af-west-africa-ebola.html. Accessed April 30, 2015.

55. The World Bank Group. Average Monthly Temperature and Rainfall for Liberia from 1990–2009. 2015. http://sdwebx.worldbank.org/climateportal/index.cfm?page=country_historical_climate&ThisRegion=Africa&ThisCCode=LBR. Accessed April 30, 2015.

56. Rutstein SO. The DHS Wealth Index: Approaches for Rural and Urban Areas. 2008;No. 60.

57. Kruk ME, Hermosilla S, Larson E, Vail D, Chen Q, Mazuguni F, et al. Who is left behind on the road to universal facility delivery? A cross-sectional multilevel analysis in rural Tanzania. Trop Med Int Health 2015 Apr 15.

58. Lohela TJ, Campbell OM, Gabrysch S. Distance to care, facility delivery and early neonatal mortality in Malawi and Zambia. PLoS ONE 2012;7(12):e52110. doi: 10.1371/journal.pone.0052110 23300599

59. Gabrysch S, Cousens S, Cox J, Campbell OM. The influence of distance and level of care on delivery place in rural Zambia: a study of linked national data in a geographic information system. PLoS Med 2011 Jan 25;8(1):e1000394. doi: 10.1371/journal.pmed.1000394 21283606

60. Mwaliko E, Downing R, O'Meara W, Chelagat D, Obala A, Downing T, et al. "Not too far to walk": the influence of distance on place of delivery in a western Kenya health demographic surveillance system. BMC Health Serv Res 2014 May 10;14:212-6963-14-212.

61. Gartland MG, Taryor VD, Norman AM, Vermund SH. Access to facility delivery and caesarean section in north-central Liberia: a cross-sectional community-based study. BMJ Open 2012 Oct 31;2(6):doi: 10.1136/bmjopen-2012-001602 Print 2012.

62. Newson R. Parameters behind nonparametric statistics: Kendall's tau, Somers' D and median differences. Stata Journal 2002;2(1):45–64(20).

63. Newson R. Confidence intervals for rank statistics: Somers' D and extensions. Stata Journal 2006;6(3):309–334(26).

64. Weinberg CR. Toward a clearer definition of confounding. Am J Epidemiol 1993 Jan 1;137(1):1–8. 8434568

65. Dynes MM, Miller L, Sam T, Vandi MA, Tomczyk B, Centers for Disease Control and Prevention (CDC). Perceptions of the risk for Ebola and health facility use among health workers and pregnant and lactating women—Kenema District, Sierra Leone, September 2014. MMWR Morb Mortal Wkly Rep 2015 Jan 2;63(51):1226–1227. 25551595

66. Yansaneh IS. Construction and Use of Sampling Weights. Expert Group Meeting to Review the Draft Handbook on Designing of Household Sample Surveys 2003 November 3, 2003;ESA/STAT/AC.93/5.

67. Porto Alves MC, Silva NN. Variance estimation methods in samples from household surveys. Rev Saude Publica 2007 Dec;41(6):938–946. 17992355

68. Kish L, Frankel MR. Inference from complex samples. Journal of the Royal Statistical Society, Series B 1974;36:1–37.

69. Hill AB. The Environment and Disease: Association or Causation? Proc R Soc Med 1965 05;58(5):295–300.

70. Savitz DA. Interpreting epidemiologic evidence: strategies for study design and analysis. Oxford; New York: Oxford University Press; 2003.

71. Groves Robert M., Fowler Floyd J., Couper Mick., Lepkowski, James M., Singer, Eleanor.,Tourangeau, Roger.,. Survey methodology. Hoboken, N.J.: Wiley; 2009.

72. Banda JP. Nonsamping Errors in Surveys. Expert Group Meeting to Review the Draft Handbook on Designing of Household Sample Surveys 2003 November 3, 2003;ESA/STAT/AC.93/7.

73. Vaessen M, Thiam M, Le T. The Demographic and Health Surveys. In: United Nations Statistics Division, editor. Household Sample Surveys in Developing and Transition Countries New York: United Nations; 2005. p. 495–522.

74. Kobayashi M, Beer KD, Bjork A, Chatham-Stephens K, Cherry CC, Arzoaquoi S, et al. Community Knowledge, Attitudes, and Practices Regarding Ebola Virus Disease—Five Counties, Liberia, September-October, 2014. MMWR Morb Mortal Wkly Rep 2015 Jul 10;64(26):714–718. 26158352

75. Liberia Ministry of Health and Social Welfare. National Knowledge, Attitudes, and Practices (KAP) Study on Ebola Virus Disease in Liberia. 2015:1–98.

76. Barbiero VK. It's not Ebola … it's the systems. Global Health: Science and Practice 2014 December 01;2(4):374–375.

77. Wilkinson A, Leach M. BRIEFING: EBOLA—MYTHS, REALITIES, AND STRUCTURAL VIOLENCE. African Affairs 2014 December 04.

78. Kamal-Yanni M. Building Resilient Health Systems and Learning from the Ebola Crisis. 2015;Oxfam Briefing Paper 203.

79. Oliphant NP, Muniz M, Guenther T, Diaz T, Lainez YB, Counihan H, et al. Multi-country analysis of routine data from integrated community case management (iCCM) programs in sub-Saharan Africa. J Glob Health 2014 Dec;4(2):020408. doi: 10.7189/jogh.04.020408 25520798

80. Lassi ZS, Haider BA, Bhutta ZA. Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes. Cochrane Database Syst Rev 2010 Nov 10;(11):CD007754. doi(11):CD007754. doi: 10.1002/14651858.CD007754.pub2 21069697

81. Amouzou A, Morris S, Moulton LH, Mukanga D. Assessing the impact of integrated community case management (iCCM) programs on child mortality: Review of early results and lessons learned in sub-Saharan Africa. J Glob Health 2014 Dec;4(2):020411. doi: 10.7189/jogh.04.020411 25520801

82. Lewin S, Munabi-Babigumira S, Glenton C, Daniels K, Bosch-Capblanch X, van Wyk BE, et al. Lay health workers in primary and community health care for maternal and child health and the management of infectious diseases. Cochrane Database Syst Rev 2010 Mar 17;(3):CD004015. doi(3):CD004015. doi: 10.1002/14651858.CD004015.pub3 20238326

83. Risso-Gill I, Finnegan L. Children's Ebola Recovery Assessment: Sierra Leone. 2015.

84. Seifman R, Kornblet S, Standley C, Sorrell E, Fischer J, Katz R. Think big, World Bank: time for a public health safeguard. Lancet Glob Health 2015 Apr;3(4):e186–7. doi: 10.1016/S2214-109X(15)70012-4 25678307

85. American Anthropological Association. Strengthening West African Health Care Systems to Stop Ebola. 2014.

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