Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine


In a phase 2 clinical trial in which patients received afatinib, plus vinorelbine on disease progression, Charles Swanton and colleagues study the mutational events in HER2-positive inflammatory breast cancers alongside early-stage clinical outcomes.


Vyšlo v časopise: Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine. PLoS Med 13(12): e32767. doi:10.1371/journal.pmed.1002136
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pmed.1002136

Souhrn

In a phase 2 clinical trial in which patients received afatinib, plus vinorelbine on disease progression, Charles Swanton and colleagues study the mutational events in HER2-positive inflammatory breast cancers alongside early-stage clinical outcomes.


Zdroje

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