PLOS Medicine - Číslo 12/2016


Cancer Genomics: Large-Scale Projects Translate into Therapeutic Advances


Overcoming Steroid Resistance in T Cell Acute Lymphoblastic Leukemia
Precision Cancer Diagnostics: Tracking Genomic Evolution in Clinical Trials
Immunotherapy in the Precision Medicine Era: Melanoma and Beyond
Sequencing Strategies to Guide Decision Making in Cancer Treatment
Blood-Based Analysis of Circulating Cell-Free DNA and Tumor Cells for Early Cancer Detection

Research Article

Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases
Expression of lncRNAs in Low-Grade Gliomas and Glioblastoma Multiforme: An In Silico Analysis
Exploratory Analysis of Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study
The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program “CASCADE”
Predictors of Chemosensitivity in Triple Negative Breast Cancer: An Integrated Genomic Analysis
Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study
Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study
Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study
IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study
Base-Position Error Rate Analysis of Next-Generation Sequencing Applied to Circulating Tumor DNA in Non-Small Cell Lung Cancer: A Prospective Study
Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine
Mutational Profile of Metastatic Breast Cancers: A Retrospective Analysis
Genomic Analysis of Uterine Lavage Fluid Detects Early Endometrial Cancers and Reveals a Prevalent Landscape of Driver Mutations in Women without Histopathologic Evidence of Cancer: A Prospective Cross-Sectional Study

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