Polyméry s molekulovými odtlačkami


Polyméry s molekulovými odtlačkami

V súčasnosti je známych približne 28 miliónov rôznych jednoduchých alebo komplikovaných zlúčenín. Dnes si ťažko môžeme predstaviť život bez rôznorodých druhov liečiv, kozmetických prípravkov, pesticídov, prísad do potravín, alebo povzbudzujúcich prostriedkov. V poslednom čase v oblasti analytickej chémii, alebo farmácie stále viac sa vyžaduje použiť moderné techniky alebo nové metodológie, ktoré umožňujú selektívne stanovenie rôznych analytov, zvlášť v zložitých biologických vzorkách. Stále častejšie na prípravu vzoriek k analýze sa využívajú polyméry s molekulovými odtlačkami, pomocou ktorých možno značne zabrániť interferenciám pri stanovení stopových koncentrácií analytov. Tato práca sa zaoberá charakterizáciou, prípravou, vlastnosťami a aplikáciou polymérov s molekulovými odtlačkami v oblasti analýzy vzoriek liečiv, kozmetických prípravkov, potravín a biologických materiálov.

Klíčová slova:
polyméry s olekulovými odtlačkami, hromatografia, extrakcia, liečiva


Autoři: Natalia Denderz;  Jozef Lehotay;  Jozef Čižmárik
Působiště autorů: Slovak University of Technology in Bratislava, Faculty of Chemical and Food Technology, Institute of Analytical Chemistry, Slovak Republic ;  Comenius University in Bratislava, Faculty of Pharmacy, Department of Pharmaceutical Chemistry
Vyšlo v časopise: Čes. slov. Farm., 2012; 61, 79-86
Kategorie: Přehledy a odborná sdělení

Souhrn

V súčasnosti je známych približne 28 miliónov rôznych jednoduchých alebo komplikovaných zlúčenín. Dnes si ťažko môžeme predstaviť život bez rôznorodých druhov liečiv, kozmetických prípravkov, pesticídov, prísad do potravín, alebo povzbudzujúcich prostriedkov. V poslednom čase v oblasti analytickej chémii, alebo farmácie stále viac sa vyžaduje použiť moderné techniky alebo nové metodológie, ktoré umožňujú selektívne stanovenie rôznych analytov, zvlášť v zložitých biologických vzorkách. Stále častejšie na prípravu vzoriek k analýze sa využívajú polyméry s molekulovými odtlačkami, pomocou ktorých možno značne zabrániť interferenciám pri stanovení stopových koncentrácií analytov. Tato práca sa zaoberá charakterizáciou, prípravou, vlastnosťami a aplikáciou polymérov s molekulovými odtlačkami v oblasti analýzy vzoriek liečiv, kozmetických prípravkov, potravín a biologických materiálov.

Klíčová slova:
polyméry s olekulovými odtlačkami, hromatografia, extrakcia, liečiva


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