Bilateral acquired stenosis of the choans and velopharynx following radiotherapy for nasopharyngeal carcinoma
Oboustranná získaná stenóza choan a velofaryngu po radioterapii nazofaryngeálního karcinomu
Choanální i velofaryngeální stenóza představují vzácné pozdní komplikace radioterapie nazofaryngeálního karcinomu. Představujeme případ 65letého pacienta, který 4 roky po ukončení radioterapie pro nazofaryngeální karcinom začal trpět progresivní oboustrannou nosní obstrukcí, anosmií, rinoreou bez přítomnosti krvácení. Diagnóza byla stanovena na základě endoskopického vyšetření nosní dutiny, histologie a CT vyšetření. Pacient podstoupil rekanalizaci choan a velofaryngu pomocí endoskopické endonazální chirurgie s následnou kalibrací trubicovým stentem, což vedlo k výraznému zlepšení obtíží. Po 24 měsících od zákroku nebyla zaznamenána recidiva stenózy.
Klíčová slova:
radioterapie – karcinom – stenóza – nazofaryngeální – choany – velofarynx
Authors:
I. Kalivoda 1; J. Syrovátka 1; M. Matzenauer 2
Authors‘ workplace:
Oddělení otorinolaryngologie a chirurgie hlavy a krku, Nemocnice AGEL Nový Jičín, a. s.
1; Oddělení radioterapie a onkologie, Komplexní onkologické centrum, Nemocnice AGEL Nový Jičín, a. s.
2
Published in:
Otorinolaryngol Foniatr, 75, 2026, No. Ahead of Print, pp. 1-5.
Category:
Case Reports
doi:
https://doi.org/10.48095/ccorl2026-007
Overview
Choanal and velopharyngeal stenoses are rare late complications of radiotherapy for nasopharyngeal carcinoma. We present the case of a 65-year - -old patient who developed progressive bilateral nasal obstruction, anosmia, and rhinorrhea without epistaxis, occurring four years after the completion of radiotherapy. The diagnosis was established based on nasal endoscopy, histopathological analysis, and computed tomography. The patient underwent endoscopic endonasal surgical recanalization of the choanae and velopharynx, followed by stent calibration using a soft tubular silicone catheter. The procedure led to marked symptomatic improvement. No evidence of restenosis was observed at 24-month follow-up.
Keywords:
Stenosis – cancer – radiotherapy – nasopharyngeal – choanae – velopharynx
Labels
Audiology Paediatric ENT ENT (Otorhinolaryngology)Article was published in
Otorhinolaryngology and Phoniatrics
2026 Issue Ahead of Print
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